A biodegradable polymersome containing Bcl-xL siRNA and doxorubicin as a dual delivery vehicle for a synergistic anticancer effect

Macromolecular Bioscience

Volumn 13, Issue 6, 2013, Pages 745-754

  Kim, Hyun Ouk ^a   Kim, Eunjung ^a   An, Yonghee ^a   Choi, Jihye ^a   Jang, EunjiH O ^a   Choi, Eun Bi ^a   Kukreja, Aastha ^a   Kim, Myeong Hoon ^a   Kang, Byunghoon ^a   Kim, Dong Joo ^a   Suh, Jin Suck ^a   Huh, Yong Min ^a   Haam, Seungjoo ^a  

^a Yonsei University   (South Korea)

Author keywords

Bcl xL specific siRNA; Biodegradable; Doxorubicin; Drug delivery systems; Polymersomes

Indexed keywords

BCL-XL-SPECIFIC SIRNA; BIODEGRADABLE; DOXORUBICIN; DRUG DELIVERY SYSTEM; POLYMERSOMES;

BLOCK COPOLYMERS; CELL CULTURE; DRUG DELIVERY; GENES; MOTION PICTURE EXPERTS GROUP STANDARDS; POLYETHYLENE GLYCOLS;

BIODEGRADABLE POLYMERS;

DOXORUBICIN; METHOXY POLY(ETHYLENE GLYCOL) BLOCK POLY(DEXTRO,LEVO LACTIC ACID); POLYETHYLENE; POLYMER; POLYMERSOME; PROTEIN BCL XL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG MECHANISM; HUMAN; HUMAN CELL; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; CELL SURVIVAL; CRYOELECTRON MICROSCOPY; DOXORUBICIN; DRUG DELIVERY SYSTEMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; INHIBITORY CONCENTRATION 50; KINETICS; POLYESTERS; POLYETHYLENE GLYCOLS; RNA, MESSENGER; RNA, SMALL INTERFERING; TIME FACTORS;

EID: 84879459868     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201200448     Document Type: Article

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