Precision intracellular delivery based on optofluidic polymersome rupture

ACS Nano

Volumn 6, Issue 9, 2012, Pages 7850-7857

  Vasdekis, Andreas E ^a   Scott, Evan A ^b   O'Neil, Conlin P ^b   Psaltis, Demetri ^a   Hubbell, Jeffrey A ^b  

^a Institute of Bioengineering (IBI)   (Switzerland)

^b EPFL   (Switzerland)

Author keywords

biophotonics; immunology; optofluidics; polymersomes; single cell analysis; vesicles

Indexed keywords

BIO PHOTONICS; OPTO-FLUIDICS; POLYMERSOMES; SINGLECELL ANALYSIS; VESICLES;

CELLS; CYTOLOGY; IMMUNOLOGY; LIPOSOMES; PHOTOEXCITATION; PHOTONICS; PHOTOSENSITIZERS;

POLYMERS;

NANOCAPSULE; POLYMER;

ARTICLE; CELL CULTURE; CHEMISTRY; DELAYED RELEASE FORMULATION; DENDRITIC CELL; DIFFUSION; HUMAN; LIGHT; MATERIALS TESTING; RADIATION EXPOSURE;

CELLS, CULTURED; DELAYED-ACTION PREPARATIONS; DENDRITIC CELLS; DIFFUSION; HUMANS; LIGHT; MATERIALS TESTING; NANOCAPSULES; POLYMERS;

EID: 84866704171     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn302122h     Document Type: Article

References (55)

1. Hubbell, J. A.; Thomas, S. N.; Swartz, M. A. Materials Engineering for Immunomodulation Nature 2009, 462, 449-460
2. Luo, D.; Saltzman, W. M. Synthetic DNA Delivery Systems Nat. Biotechnol. 2000, 18, 33-37
3. Pack, D. W.; Hoffman, A. S.; Pun, S.; Stayton, P. S. Design and Development of Polymers for Gene Delivery Nat. Rev. Drug Discovery 2005, 4, 581-593
4. Peer, D.; Karp, J. M.; Hong, S.; FaroKhzad, O. C.; Margalit, R.; Langer, R. Nanocarriers as an Emerging Platform for Cancer Therapy Nat. Nanotechnol. 2007, 2, 751-760
5. Prokop, A. Intracellular Delivery Fundamentals and Applications; Springer: Berlin, 2011.
6. Okada, C. Y.; Rechsteiner, M. Introduction of Macromolecules into Cultured Mammalian-Cells by Osmotic Lysis of Pinocytic Vesicles Cell 1982, 29, 33-41
7. O'Brien, J. A.; Lummis, S. C. R. Biolistic Transfection of Neuronal Cultures Using a Hand-Held Gene Gun Nat. Protoc. 2006, 1, 977-981
8. Harding, C. V. Electroporation of Exogenous Antigen into the Cytosol for Antigen Processing and Class I Major Histocompatibility Complex (MHC) Presentation: Weak Base Amines and Hypothermia (18°C) Inhibit the Class I MHC Processing Pathway Eur. J. Immunol. 1992, 22, 1865-1869
9. Boukany, P. E.; Morss, A.; Liao, W.-C.; Henslee, B.; Jung, H.; Zhang, X.; Yu, B.; Wang, B.; Wu, Y.; Li, L. et al. Nanochannel Electroporation Delivers Precise Amounts of Biomolecules into Living Cells Nat. Nanotechnol. 2011, 6, 747-754
10. Tirlapur, U. K.; Konig, K. Cell Biology-Targeted Transfection by Femtosecond Laser Nature 2002, 418, 290-291
11. Paterson, L.; Agate, B.; Comrie, M.; Ferguson, R.; Lake, T. K.; Morris, J. E.; Carruthers, A. E.; Brown, C. T. A.; Sibbett, W.; Bryant, P. E. et al. Photoporation and Cell Transfection Using a Violet Diode Laser Opt. Express 2005, 13, 595-600
12. Berg, K.; Folini, M.; Prasmickaite, L.; Selbo, P. K.; Bonsted, A.; Engesaeter, B. O.; Zaffaroni, N.; Weyergang, A.; Dietze, A.; Maelandsmo, G. M. et al. Photochemical Internalization: A New Tool for Drug Delivery Curr. Pharm. Biotechnol. 2007, 8, 362-372
13. de Bruin, K. G.; Fella, C.; Ogris, M.; Wagner, E.; Ruthardt, N.; Brauchle, C. Dynamics of Photoinduced Endosomal Release of Polyplexes J. Controlled Release 2008, 130, 175-182
14. Berg, K.; Selbo, P. K.; Prasmickaite, L.; Tjelle, T. E.; Sandvig, K.; Moan, D.; Gaudernack, G.; Fodstad, O.; Kjolsrud, S.; Anholt, H. et al. Photochemical Internalization: A Novel Technology for Delivery of Macromolecules into Cytosol Cancer Res. 1999, 59, 1180-1183
15. Nayak, S.; Herzog, R. W. Progress and Prospects: Immune Responses to Viral Vectors Gene Ther. 2010, 17, 295-304
16. Adams, S. R.; Tsien, R. Y. Controlling Cell Chemistry with Caged Compounds Annu. Rev. Physiol. 1993, 55, 755-784
17. Palankar, R.; Skirtach, A. G.; Kreft, O.; Bedard, M.; Garstka, M.; Gould, K.; Mohwald, H.; Sukhorukov, G. B.; Winterhalter, M.; Springer, S. Controlled Intracellular Release of Peptides from Microcapsules Enhances Antigen Presentation on MHC Class I Molecules Small 2009, 5, 2168-2176
18. Javier, A. M.; del Pino, P.; Bedard, M. F.; Ho, D.; Skirtach, A. G.; Sukhorukov, G. B.; Plank, C.; Parak, W. J. Photoactivated Release of Cargo from the Cavity of Polyelectrolyte Capsules to the Cytosol of Cells Langmuir 2008, 24, 12517-12520
19. Hope, M. J.; Bally, M. B.; Webb, G.; Cullis, P. R. Production of Large Unilamellar Vesicles by a Rapid Extrusion Procedure-Characterization of Size Distribution, Trapped Volume and Ability To Maintain a Membrane Potential Biochim. Biophys. Acta, Bioenerg. 1985, 812, 55-65
20. Napoli, A.; Valentini, M.; Tirelli, N.; Muller, M.; Hubbell, J. A. Oxidation-Responsive Polymeric Vesicles Nat. Mater. 2004, 3, 183-189
21. Discher, D. E.; Eisenberg, A. Polymer Vesicles Science 2002, 297, 967-973
22. Spiller, D. G.; Wood, C. D.; Rand, D. A.; White, M. R. H. Measurement of Single-Cell Dynamics Nature 2010, 465, 736-745
23. Cerritelli, S.; O'Neil, C. P.; Velluto, D.; Fontana, A.; Adrian, M.; Dubochet, J.; Hubbell, J. A. Aggregation Behavior of Poly(ethylene glycol- bl -propylene sulfide) Di- and Triblock Copolymers in Aqueous Solution Langmuir 2009, 25, 11328-11335
24. Psaltis, D.; Quake, S. R.; Yang, C. H. Developing Optofluidic Technology through the Fusion of Microfluidics and Optics Nature 2006, 442, 381-386
25. Monat, C.; Domachuk, P.; Eggleton, B. J. Integrated Optofluidics: A New River of Light Nat. Photonics 2007, 1, 106-114
26. Alvarez-Lorenzo, C.; Bromberg, L.; Concheiro, A. Light-Sensitive Intelligent Drug Delivery Systems Photochem. Photobiol. 2009, 85, 848-860
27. Timko, B. P.; Dvir, T.; Kohane, D. S. Remotely Triggerable Drug Delivery Systems Adv. Mater. 2010, 22, 4925-4943
28. Mabrouk, E.; Cuvelier, D.; Brochard-Wyart, F.; Nassoy, P.; Li, M. H. Bursting of Sensitive Polymersomes Induced by Curling Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 7294-7298
29. Anderson, V. C.; Thompson, D. H. Triggered Release of Hydrophilic Agents from Plasmalogen Liposomes Using Visible Light or Acid Biochim. Biophys. Acta, Bioenerg. 1992, 1109, 33-42
30. De Geest, B. G.; McShane, M. J.; Demeester, J.; De Smedt, S. C.; Hennink, W. E. Microcapsules Ejecting Nanosized Species into the Environment J. Am. Chem. Soc. 2008, 130, 14480-14482
31. Robbins, G. P.; Jimbo, M.; Swift, J.; Therien, M. J.; Hammer, D. A.; Dmochowski, I. J. Photoinitiated Destruction of Composite Porphyrin-Protein Polymersomes J. Am. Chem. Soc. 2009, 131, 3872-3874
32. Miller, C. R.; Clapp, P. J.; O'Brien, D. F. Visible Light-Induced Destabilization of Endocytosed Liposomes FEBS Lett. 2000, 467, 52-56
33. Yavlovich, A.; Singh, A.; Blumenthal, R.; Puri, A. A Novel Class of Photo-Triggerable Liposomes Containing DPPC:DC(8,9)PC as Vehicles for Delivery of Doxorubcin to Cells Biochim. Biophys. Acta, Biomembr. 2011, 1808, 117-126
34. Lee, S. E.; Liu, G. L.; Kim, F.; Lee, L. P. Remote Optical Switch for Localized and Selective Control of Gene Interference Nano Lett. 2009, 9, 562-570
35. Huschka, R.; Neumann, O.; Barhoumi, A.; Halas, N. J. Visualizing Light-Triggered Release of Molecules Inside Living Cells Nano Lett. 2010, 10, 4117-4122
36. Gregersen, K. A. D.; Hill, Z. B.; Gadd, J. C.; Fujimoto, B. S.; Maly, D. J.; Chiu, D. T. Intracellular Delivery of Bioactive Molecules Using Light-Addressable Nanocapsules ACS Nano 2010, 4, 7603-7611
37. Norum, O.-J.; Selbo, P. K.; Weyergang, A.; Giercksky, K.-E.; Berg, K. Photochemical Internalization (PCI) in Cancer Therapy: From Bench towards Bedside Medicine J. Photochem. Photobiol., B 2009, 96, 83-92
38. Christian, D. A.; Cai, S.; Bowen, D. M.; Kim, Y.; Pajerowski, J. D.; Discher, D. E. Polymersome Carriers: From Self-Assembly to siRNA and Protein Therapeutics Eur. J. Pharm. Biopharm. 2009, 71, 463-474
39. Foote, C. S. Mechanisms of Photosensitized Oxidation Science 1968, 162, 963-970
40. Valenzeno, D. P. Photomodification of Biological Membranes with Emphasis on Singlet Oxygen Mechanisms Photochem. Photobiol. 1987, 46, 147-160
41. Zhu, T. F.; Szostak, J. W. Exploding Vesicles J. Syst. Chem. 2011, 2, 1-6
42. Beghetto, C.; Renken, C.; Eriksson, O.; Jori, G.; Bernardi, P.; Ricchelli, F. Implications of the Generation of Reactive Oxygen Species by Photoactivated Calcein for Mitochondrial Studies Eur. J. Biochem. 2000, 267, 5585-5592
43. Cerritelli, S.; Velluto, D.; Hubbell, J. A. PEG-SS-PPS: Reduction-Sensitive Disulfide Block Copolymer Vesicles for Intracellular Drug Delivery Biomacromolecules 2007, 8, 1966-1972
44. Yuba, E.; Kojima, C.; Harada, A.; Tana; Watarai, S.; Kono, K. pH-Sensitive Fusogenic Polymer-Modified Liposomes as a Carrier of Antigenic Proteins for Activation of Cellular Immunity Biomaterials 2010, 31, 943-951
45. Neil, A. E.; Madler, L.; Velegol, D.; Xia, T.; Hoelk, E. M. V.; Somasundaran, P.; Klaessig, F.; Castranova, V.; Thompson, M. Understanding Biophysicochemical Interactions at the Nano-Bio Interface Nat. Mater. 2009, 8, 543-557
46. Skirtach, A. G.; Javier, A. M.; Kreft, O.; Kohler, K.; Alberola, A. P.; Mohwald, H.; Parak, W. J.; Sukhorukov, G. B. Laser-Induced Release of Encapsulated Materials Inside Living Cells Angew. Chem., Int. Ed. 2006, 45, 4612-4617
47. Cho, N.-H.; Cheong, T.-C.; Min, J.-H.; Wu, J.-H.; Lee, S.-J.; Kim, D.; Yang, J.-S.; Kim, S.; Kim, Y.-K.; Seong, S.-Y. A Multifunctional Core-Shell Nanoparticle for Dendritic Cell-Based Cancer Immunotherapy Nat. Nanotechnol. 2011, 6, 675-682
48. Reits, E.; Griekspoor, A.; Neijssen, J.; Groothuis, T.; Jalink, K.; van Veelen, P.; Janssen, H.; Calafat, J.; Drijfhout, J. W.; Neefjes, J. Peptide Diffusion, Protection, and Degradation in Nuclear and Cytoplasmic Compartments Before Antigen Presentation by MHC Class I Immunity 2003, 18, 97-108
49. Yewdell, J. W. Not Such a Dismal Science: The Economics of Protein Synthesis, Folding, Degradation and Antigen Processing Trends Cell Biol. 2001, 11, 294-297
50. Kukutsch, N. A.; Rossner, S.; Austyn, J. M.; Schuler, G.; Lutz, M. B. Formation and Kinetics of MHC Class I-Ovalbumin Peptide Complexes on Immature and Mature Murine Dendritic Cells J. Invest. Dermatol. 2000, 115, 449-453
51. Kim, D. T.; Mitchell, D. J.; Brockstedt, D. G.; Fong, L.; Nolan, G. P.; Fathman, C. G.; Engleman, E. G.; Rothbard, J. B. Introduction of Soluble Proteins into the MHC Class I Pathway by Conjugation to an HIV Tat Peptide J. Immunol. 1997, 159, 1666-1668
52. Napoli, A.; Tirelli, N.; Kilcher, G.; Hubbell, J. A. New Synthetic Methodologies for Amphiphilic Multiblock Copolymers of Ethylene Glycol and Propylene Sulfide Macromolecules 2001, 34, 8913-8917
53. Oyama, T.; Naka, K.; Chujo, Y. Polymer Homologue of DMSO: Synthesis of Poly(ethylene sulfoxide) by Selective Oxidation of Poly(ethylene sulfide) Macromolecules 1999, 32, 5240-5242
54. Dubochet, J.; Adrian, M.; Chang, J. J.; Homo, J. C.; Lepault, J.; Mcdowall, A. W.; Schultz, P. Cryo-Electron Microscopy of Vitrified Specimens Q. Rev. Biophys. 1988, 21, 129-228
55. Cuennet, J.; Vasdekis, A. E.; De Sio, L.; Psaltis, D. Optofluidic Modulator Based on Peristaltic Nematogen Microflows Nat. Photonics 2011, 5, 234-238