메뉴 건너뛰기




Volumn 14, Issue 6, 2013, Pages 12806-12826

Putative genes involved in saikosaponin biosynthesis in Bupleurum species

Author keywords

Anti hepatitis; Anti inflammation; Bupleurum species; Ethylene response factor; Medicinal herb; Methyl jasmonate (MeJA); Saikosaponin; Triterpenoid

Indexed keywords

BETA AMYRIN; JASMONIC ACID METHYL ESTER; SAIKOSAPONIN; SAIKOSAPONIN A; SAIKOSAPONIN C; SAIKOSAPONIN D; TRITERPENE; TRITERPENOID; OLEANOLIC ACID; SAPONIN;

EID: 84879329431     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms140612806     Document Type: Review
Times cited : (35)

References (104)
  • 1
    • 79952231420 scopus 로고    scopus 로고
    • Genus Bupleurum: A review of its phytochemistry, pharmacology and modes of action
    • Ashour, M.L.; Wink, M. Genus Bupleurum: A review of its phytochemistry, pharmacology and modes of action. J. Pharm. Pharmacol. 2011, 63, 305-332.
    • (2011) J. Pharm. Pharmacol , vol.63 , pp. 305-332
    • Ashour, M.L.1    Wink, M.2
  • 4
    • 84881289890 scopus 로고    scopus 로고
    • Network analysis for gene discovery in plant specialized metabolism
    • doi:10.1111/pce.12069
    • Higashi, Y.; Saito, K. Network analysis for gene discovery in plant specialized metabolism. Plant Cell Environ. 2013, doi:10.1111/pce.12069.
    • (2013) Plant Cell Environ
    • Higashi, Y.1    Saito, K.2
  • 5
    • 37849020436 scopus 로고    scopus 로고
    • Decoding genes with coexpression 603 networks and metabolomics-'Majority report by precogs'
    • Saito, K.; Hirai, M.Y.; Yonekura-Sakakibara, K. Decoding genes with coexpression 603 networks and metabolomics-'Majority report by precogs'. Trends Plant Sci. 2008, 13, 36-43.
    • (2008) Trends Plant Sci , vol.13 , pp. 36-43
    • Saito, K.1    Hirai, M.Y.2    Yonekura-Sakakibara, K.3
  • 7
    • 42549149198 scopus 로고    scopus 로고
    • Rapid authentication of Bupleurum species using an array of immobilized sequence-specific oligonucleotide probes
    • Lin, W.Y.; Chen, L.R.; Lin, T.Y. Rapid authentication of Bupleurum species using an array of immobilized sequence-specific oligonucleotide probes. Planta Med. 2008, 74, 464-469.
    • (2008) Planta Med , vol.74 , pp. 464-469
    • Lin, W.Y.1    Chen, L.R.2    Lin, T.Y.3
  • 8
    • 21144443928 scopus 로고    scopus 로고
    • The hepatoprotective effect of Bupleurum kaoi, an endemic plant to Taiwan, against dimethylnitrosamine-induced hepatic fibrosis in rats
    • Yen, M.H.; Weng, T.C.; Liu, S.Y.; Chai, C.Y.; Lin, C.C. The hepatoprotective effect of Bupleurum kaoi, an endemic plant to Taiwan, against dimethylnitrosamine-induced hepatic fibrosis in rats. Biol. Pharm. Bull. 2005, 28, 442-448.
    • (2005) Biol. Pharm. Bull , vol.28 , pp. 442-448
    • Yen, M.H.1    Weng, T.C.2    Liu, S.Y.3    Chai, C.Y.4    Lin, C.C.5
  • 12
    • 23244460963 scopus 로고    scopus 로고
    • Determination of saikosaponins a, c, and d in Bupleurum Chinese DC from different areas by capillary zone electrophoresis
    • Lin, X.; Xue, L.; Zhang, H.; Zhu, C. Determination of saikosaponins a, c, and d in Bupleurum Chinese DC from different areas by capillary zone electrophoresis. Anal. Bioanal. Chem. 2005, 382, 1610-1615.
    • (2005) Anal. Bioanal. Chem , vol.382 , pp. 1610-1615
    • Lin, X.1    Xue, L.2    Zhang, H.3    Zhu, C.4
  • 13
    • 62749122903 scopus 로고    scopus 로고
    • Fast determination of saikosaponins in Bupleurum by rapid resolution liquid chromatography with evaporative light scattering detection
    • Huang, H.Q.; Zhang, X.; Xu, Z.X.; Su, J.; Yan, S.K.; Zhang, W.D. Fast determination of saikosaponins in Bupleurum by rapid resolution liquid chromatography with evaporative light scattering detection. J. Pharm. Biomed. Anal. 2009, 49, 1048-1055.
    • (2009) J. Pharm. Biomed. Anal , vol.49 , pp. 1048-1055
    • Huang, H.Q.1    Zhang, X.2    Xu, Z.X.3    Su, J.4    Yan, S.K.5    Zhang, W.D.6
  • 15
    • 33845416990 scopus 로고    scopus 로고
    • Antiproliferative constituents from Umbelliferae plants. IX. New triterpenoid glycosides from the fruits of Bupleurum rotundifolium
    • Fujioka, T.; Yoshida, K.; Shibao, H.; Nagao, T.; Yoshida, M.; Matsunaga, K.; Takata, J.; Karube, Y.; Iwase, Y.; Okabe, H., et al. Antiproliferative constituents from Umbelliferae plants. IX. New triterpenoid glycosides from the fruits of Bupleurum rotundifolium. Chem. Pharm. Bull. 2006, 54, 1694-1704.
    • (2006) Chem. Pharm. Bull , vol.54 , pp. 1694-1704
    • Fujioka, T.1    Yoshida, K.2    Shibao, H.3    Nagao, T.4    Yoshida, M.5    Matsunaga, K.6    Takata, J.7    Karube, Y.8    Iwase, Y.9    Okabe, H.10
  • 16
    • 0027630537 scopus 로고
    • Saikosaponin derivatives from Bupleurum wenchuanense
    • Luo, S.Q.; Lin, L.Z.; Cordell, G.A. Saikosaponin derivatives from Bupleurum wenchuanense. Phytochemistry 1993, 33, 1197-1205.
    • (1993) Phytochemistry , vol.33 , pp. 1197-1205
    • Luo, S.Q.1    Lin, L.Z.2    Cordell, G.A.3
  • 17
    • 0028199779 scopus 로고
    • Biologically active triterpene saponins from Bupleurum fruticosum
    • Guinea, M.C.; Parellada, J.; Lacaille-Dubois, M.A.; Wagner, H. Biologically active triterpene saponins from Bupleurum fruticosum. Planta Med. 1994, 60, 163-167.
    • (1994) Planta Med , vol.60 , pp. 163-167
    • Guinea, M.C.1    Parellada, J.2    Lacaille-Dubois, M.A.3    Wagner, H.4
  • 18
    • 0016810474 scopus 로고
    • Structure and actions of saikosaponins isolated from Bupleurum falcatum L. I. Anti-inflammatory action of saikosaponins
    • Yamamoto, M.; Kumagai, A.; Yamamura, Y. Structure and actions of saikosaponins isolated from Bupleurum falcatum L. I. Anti-inflammatory action of saikosaponins. Arzneimittelforschung 1975, 25, 1021-1023.
    • (1975) Arzneimittelforschung , vol.25 , pp. 1021-1023
    • Yamamoto, M.1    Kumagai, A.2    Yamamura, Y.3
  • 19
    • 0019170333 scopus 로고
    • Pharmacological actions of saikosaponins isolated from Bupleurum falcatum. 1. Effects of saikosaponins on liver function
    • Abe, H.; Sakaguchi, M.; Yamada, M.; Arichi, S.; Odashima, S. Pharmacological actions of saikosaponins isolated from Bupleurum falcatum. 1. Effects of saikosaponins on liver function. Planta Med. 1980, 40, 366-372.
    • (1980) Planta Med , vol.40 , pp. 366-372
    • Abe, H.1    Sakaguchi, M.2    Yamada, M.3    Arichi, S.4    Odashima, S.5
  • 21
    • 32344449646 scopus 로고    scopus 로고
    • Haemolytic activities and adjuvant effect of Bupleurum chinense saponins on the immune responses to ovalbumin in mice
    • Sun, H.X. Haemolytic activities and adjuvant effect of Bupleurum chinense saponins on the immune responses to ovalbumin in mice. Vaccine 2006, 24, 1324-1331.
    • (2006) Vaccine , vol.24 , pp. 1324-1331
    • Sun, H.X.1
  • 22
    • 0035951418 scopus 로고    scopus 로고
    • In vivo anti-inflammatory activity of saponins from Bupleurum rotundifolium
    • Navarro, P.; Giner, R.M.; Recio, M.C.; Manez, S.; Cerda-Nicolas, M.; Rios, J.L. In vivo anti-inflammatory activity of saponins from Bupleurum rotundifolium. Life Sci. 2001, 68, 1199-1206.
    • (2001) Life Sci , vol.68 , pp. 1199-1206
    • Navarro, P.1    Giner, R.M.2    Recio, M.C.3    Manez, S.4    Cerda-Nicolas, M.5    Rios, J.L.6
  • 24
    • 0026341494 scopus 로고
    • The effects of saikosaponin on macrophage functions and lymphocyte proliferation
    • Ushio, Y.; Abe, H. The effects of saikosaponin on macrophage functions and lymphocyte proliferation. Planta Med. 1991, 57, 511-514.
    • (1991) Planta Med , vol.57 , pp. 511-514
    • Ushio, Y.1    Abe, H.2
  • 25
    • 66149145372 scopus 로고    scopus 로고
    • Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation
    • Wong, V.K.; Zhou, H.; Cheung, S.S.; Li, T.; Liu, L. Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation. J. Cell. Biochem. 2009, 107, 303-315.
    • (2009) J. Cell. Biochem , vol.107 , pp. 303-315
    • Wong, V.K.1    Zhou, H.2    Cheung, S.S.3    Li, T.4    Liu, L.5
  • 26
    • 0036287107 scopus 로고    scopus 로고
    • Effect of saikosaponin-A, a triterpenoid glycoside, isolated from Bupleurum falcatum on experimental allergic asthma
    • Park, K.H.; Park, J.; Koh, D.; Lim, Y. Effect of saikosaponin-A, a triterpenoid glycoside, isolated from Bupleurum falcatum on experimental allergic asthma. Phytother. Res. 2002, 16, 359-363.
    • (2002) Phytother. Res , vol.16 , pp. 359-363
    • Park, K.H.1    Park, J.2    Koh, D.3    Lim, Y.4
  • 27
    • 70649092057 scopus 로고    scopus 로고
    • Estrogen-like activities of saikosaponin-d in vitro: A pilot study
    • Wang, P.; Ren, J.; Tang, J.; Zhang, D.; Li, B.; Li, Y. Estrogen-like activities of saikosaponin-d in vitro: A pilot study. Eur. J. Pharmacol. 2010, 626, 159-165.
    • (2010) Eur. J. Pharmacol , vol.626 , pp. 159-165
    • Wang, P.1    Ren, J.2    Tang, J.3    Zhang, D.4    Li, B.5    Li, Y.6
  • 28
    • 67349212587 scopus 로고    scopus 로고
    • Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis
    • Sun, Y.; Cai, T.T.; Zhou, X.B.; Xu, Q. Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis. Int. Immunopharmacol. 2009, 9, 978-983.
    • (2009) Int. Immunopharmacol , vol.9 , pp. 978-983
    • Sun, Y.1    Cai, T.T.2    Zhou, X.B.3    Xu, Q.4
  • 29
    • 79957993237 scopus 로고    scopus 로고
    • Inactivation of cysteine-aspartic acid protease (caspase)-1 by saikosaponin A
    • Han, N.R.; Kim, H.M.; Jeong, H.J. Inactivation of cysteine-aspartic acid protease (caspase)-1 by saikosaponin A. Biol. Pharm. Bull. 2011, 34, 817-823.
    • (2011) Biol. Pharm. Bull , vol.34 , pp. 817-823
    • Han, N.R.1    Kim, H.M.2    Jeong, H.J.3
  • 30
    • 78649784579 scopus 로고    scopus 로고
    • Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells
    • Wang, Q.; Zheng, X.L.; Yang, L.; Shi, F.; Gao, L.B.; Zhong, Y.J.; Sun, H.; He, F.; Lin, Y.; Wang, X. Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells. J. Exp. Clin. Cancer Res. 2010, 29, 159-166.
    • (2010) J. Exp. Clin. Cancer Res , vol.29 , pp. 159-166
    • Wang, Q.1    Zheng, X.L.2    Yang, L.3    Shi, F.4    Gao, L.B.5    Zhong, Y.J.6    Sun, H.7    He, F.8    Lin, Y.9    Wang, X.10
  • 31
    • 0031919320 scopus 로고    scopus 로고
    • Inhibitory effect of bupleuri radix saponins on adhesion of some solid tumor cells and relation to hemolytic action: Screening of 232 herbal drugs for anti-cell adhesion
    • Ahn, B.Z.; Yoon, Y.D.; Lee, Y.H.; Kim, B.H.; Sok, D.E. Inhibitory effect of bupleuri radix saponins on adhesion of some solid tumor cells and relation to hemolytic action: Screening of 232 herbal drugs for anti-cell adhesion. Planta Med. 1998, 64, 220-224.
    • (1998) Planta Med , vol.64 , pp. 220-224
    • Ahn, B.Z.1    Yoon, Y.D.2    Lee, Y.H.3    Kim, B.H.4    Sok, D.E.5
  • 33
    • 12044254693 scopus 로고
    • Enzymatic cyclization of squalene and oxidosqualene to sterols and triterpenes
    • Abe, I.; Rohmer, M.; Prestwich, G.D. Enzymatic cyclization of squalene and oxidosqualene to sterols and triterpenes. Chem. Rev. 1993, 93, 2189-2206.
    • (1993) Chem. Rev , vol.93 , pp. 2189-2206
    • Abe, I.1    Rohmer, M.2    Prestwich, G.D.3
  • 34
    • 36349025257 scopus 로고    scopus 로고
    • Enzymatic synthesis of cyclic triterpenes
    • Abe, I. Enzymatic synthesis of cyclic triterpenes. Nat. Prod. Rep. 2007, 24,1311-1331.
    • (2007) Nat. Prod. Rep , vol.24 , pp. 1311-1331
    • Abe, I.1
  • 36
    • 0036959970 scopus 로고    scopus 로고
    • A genomics approach to the early stages of triterpene saponin biosynthesis in Medicago truncatula
    • Suzuki, H.; Achnine, L.; Xu, R.; Matsuda, S.P.T.; Dixon, R.A. A genomics approach to the early stages of triterpene saponin biosynthesis in Medicago truncatula. Plant J. 2002, 32, 1033-1048.
    • (2002) Plant J , vol.32 , pp. 1033-1048
    • Suzuki, H.1    Achnine, L.2    Xu, R.3    Matsuda, S.P.T.4    Dixon, R.A.5
  • 37
    • 20144376484 scopus 로고    scopus 로고
    • Methyl jasmonate and yeast elicitor induce differential transcriptional and metabolic re-programming in cell suspension cultures of the model legume Medicago truncatula
    • Suzuki, H.; Reddy, M.S.S.; Naoumkina, M.; Aziz, N.; May, G.D.; Huhman, D.V.; Sumner, L.W.; Blount, J.W.; Mendes, P.; Dixon, R.A. Methyl jasmonate and yeast elicitor induce differential transcriptional and metabolic re-programming in cell suspension cultures of the model legume Medicago truncatula. Planta 2005, 220, 696-707.
    • (2005) Planta , vol.220 , pp. 696-707
    • Suzuki, H.1    Reddy, M.S.S.2    Naoumkina, M.3    Aziz, N.4    May, G.D.5    Huhman, D.V.6    Sumner, L.W.7    Blount, J.W.8    Mendes, P.9    Dixon, R.A.10
  • 38
    • 0035126341 scopus 로고    scopus 로고
    • UDP-glucuronosyltransferase activity is correlated to saponin production in Gypsophila paniculata root in vitro cultures
    • Hérold, M.C.; Henry, M. UDP-glucuronosyltransferase activity is correlated to saponin production in Gypsophila paniculata root in vitro cultures. Biotechnol. Lett. 2001, 23, 335-337.
    • (2001) Biotechnol. Lett , vol.23 , pp. 335-337
    • Hérold, M.C.1    Henry, M.2
  • 39
    • 77952516353 scopus 로고    scopus 로고
    • Diversification of P450 genes during land plant evolution
    • Mizutani, M.; Ohta, D. Diversification of P450 genes during land plant evolution. Annu. Rev. Plant Biol. 2010, 61, 291-315.
    • (2010) Annu. Rev. Plant Biol , vol.61 , pp. 291-315
    • Mizutani, M.1    Ohta, D.2
  • 41
    • 34248524534 scopus 로고    scopus 로고
    • Genome-wide identification and characterization of putative cytochrome P450 genes in the model legume Medicago truncatula
    • Li, L.; Cheng, H.; Gai, J.; Yu, D. Genome-wide identification and characterization of putative cytochrome P450 genes in the model legume Medicago truncatula. Planta 2007, 226, 109-123.
    • (2007) Planta , vol.226 , pp. 109-123
    • Li, L.1    Cheng, H.2    Gai, J.3    Yu, D.4
  • 42
    • 3042674420 scopus 로고    scopus 로고
    • Comparative genomics of rice and Arabidopsis. Analysis of 727 cytochrome P450 genes and pseudogenes from a monocot and a dicot
    • Nelson, D.R.; Schuler, M.A.; Paquette, S.M.; Werck-Reichhart, D; Bak, S. Comparative genomics of rice and Arabidopsis. Analysis of 727 cytochrome P450 genes and pseudogenes from a monocot and a dicot. Plant Physiol. 2004, 135, 756-772.
    • (2004) Plant Physiol , vol.135 , pp. 756-772
    • Nelson, D.R.1    Schuler, M.A.2    Paquette, S.M.3    Werck-Reichhart, D.4    Bak, S.5
  • 44
    • 84855180697 scopus 로고    scopus 로고
    • Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin
    • Seki, H.; Sawai, S.; Ohyama, K.; Mizutani, M.; Ohnishi, T.; Sudo, H.; Fukushima, E.O.; Akashi, T.; Aoki, T.; Saito, K., et al. Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin. Plant Cell 2011, 23, 4112-4123.
    • (2011) Plant Cell , vol.23 , pp. 4112-4123
    • Seki, H.1    Sawai, S.2    Ohyama, K.3    Mizutani, M.4    Ohnishi, T.5    Sudo, H.6    Fukushima, E.O.7    Akashi, T.8    Aoki, T.9    Saito, K.10
  • 45
    • 33644949950 scopus 로고    scopus 로고
    • Identification of β-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay
    • Shibuya, M.; Hoshino, M.; Katsube, Y.; Hayashi, H.; Kushiro, T.; Ebizuka, Y. Identification of β-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay. FEBS J. 2006, 273, 948-959.
    • (2006) FEBS J , vol.273 , pp. 948-959
    • Shibuya, M.1    Hoshino, M.2    Katsube, Y.3    Hayashi, H.4    Kushiro, T.5    Ebizuka, Y.6
  • 46
    • 15544364507 scopus 로고    scopus 로고
    • Genomics-based selection and functional characterization of triterpene glycosyltransferases from the model legume Medicago truncatula
    • Achnine, L.; Huhman, D.V.; Farag, M.A.; Sumner, L.W.; Blount, J.W.; Dixon, R.A. Genomics-based selection and functional characterization of triterpene glycosyltransferases from the model legume Medicago truncatula. Plant J. 2005, 41, 875-887.
    • (2005) Plant J , vol.41 , pp. 875-887
    • Achnine, L.1    Huhman, D.V.2    Farag, M.A.3    Sumner, L.W.4    Blount, J.W.5    Dixon, R.A.6
  • 47
    • 0034647914 scopus 로고    scopus 로고
    • ORCA3, a jasmonate-responsive transcriptional regulator of plant primary and secondary metabolism
    • van der Fits, L.; Memelink, J. ORCA3, a jasmonate-responsive transcriptional regulator of plant primary and secondary metabolism, Science 2000, 289, 295-297.
    • (2000) Science , vol.289 , pp. 295-297
    • van der Fits, L.1    Memelink, J.2
  • 48
    • 0034760932 scopus 로고    scopus 로고
    • Efficient production of saikosaponins in Bupleurum falcatum root fragments combined with signal transducers
    • Aoyagi, H.; Kobayashi, Y.; Yamada, K.; Yokoyama, M.; Kusakari, K.; Tanaka, H. Efficient production of saikosaponins in Bupleurum falcatum root fragments combined with signal transducers. Appl. Microbiol. Biotechnol. 2001, 57, 482-488.
    • (2001) Appl. Microbiol. Biotechnol , vol.57 , pp. 482-488
    • Aoyagi, H.1    Kobayashi, Y.2    Yamada, K.3    Yokoyama, M.4    Kusakari, K.5    Tanaka, H.6
  • 49
    • 0026520785 scopus 로고
    • Jasmonic acid is a signal transducer in elicitor-induced plant cell cultures
    • Gundlach, H.; Muller, M.J.; Kutchan, T.M.; Zenk, M.H. Jasmonic acid is a signal transducer in elicitor-induced plant cell cultures. Proc. Natl. Acad. Sci. USA 1992, 89, 2389-2393.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2389-2393
    • Gundlach, H.1    Muller, M.J.2    Kutchan, T.M.3    Zenk, M.H.4
  • 50
    • 34248637893 scopus 로고    scopus 로고
    • MeJA-induced transcriptional changes in adventitious roots of Bupleurum kaoi
    • Chen, L.R.; Chen, Y.J.; Lee, C.Y.; Lin, T.Y. MeJA-induced transcriptional changes in adventitious roots of Bupleurum kaoi. Plant Sci. 2007, 173, 12-24.
    • (2007) Plant Sci , vol.173 , pp. 12-24
    • Chen, L.R.1    Chen, Y.J.2    Lee, C.Y.3    Lin, T.Y.4
  • 51
    • 80055112904 scopus 로고    scopus 로고
    • Transcriptome analysis of Bupleurum chinense focusing on genes involved in the biosynthesis of saikosaponins
    • Sui, C.; Zhang, J.; Wei, J.; Chen, S.; Li, Y.; Xu, J.; Jin, Y.; Xie, C.; Gao, Z.; Chen, H., et al. Transcriptome analysis of Bupleurum chinense focusing on genes involved in the biosynthesis of saikosaponins. BMC Genomics 2011, 12, 539.
    • (2011) BMC Genomics , vol.12 , pp. 539
    • Sui, C.1    Zhang, J.2    Wei, J.3    Chen, S.4    Li, Y.5    Xu, J.6    Jin, Y.7    Xie, C.8    Gao, Z.9    Chen, H.10
  • 52
    • 79251597651 scopus 로고    scopus 로고
    • Gene regulation patterns in triterpene biosynthetic pathway driven by overexpression of squalene synthase and methyl jasmonate elicitation in Bupleurum falcatum
    • Kim, Y.S.; Cho, J.H.; Park, S.; Han, J.Y.; Back, K.; Choi, Y.E. Gene regulation patterns in triterpene biosynthetic pathway driven by overexpression of squalene synthase and methyl jasmonate elicitation in Bupleurum falcatum. Planta 2011, 233, 343-355.
    • (2011) Planta , vol.233 , pp. 343-355
    • Kim, Y.S.1    Cho, J.H.2    Park, S.3    Han, J.Y.4    Back, K.5    Choi, Y.E.6
  • 53
    • 77951121533 scopus 로고    scopus 로고
    • De novo sequencing and analysis of the American ginseng root transcriptome using a GS FLX Titanium platform to discover putative genes involved in ginsenoside biosynthesis
    • Sun, C.; Li, Y.; Wu, Q.; Luo, H.M.; Sun, Y.Z.; Song, J.Y.; Lui, E.; Chen, S.L. De novo sequencing and analysis of the American ginseng root transcriptome using a GS FLX Titanium platform to discover putative genes involved in ginsenoside biosynthesis. BMC Genomics 2010, 11, 262.
    • (2010) BMC Genomics , vol.11 , pp. 262
    • Sun, C.1    Li, Y.2    Wu, Q.3    Luo, H.M.4    Sun, Y.Z.5    Song, J.Y.6    Lui, E.7    Chen, S.L.8
  • 54
    • 84892719565 scopus 로고    scopus 로고
    • Triterpenoid biosynthesis and engineering in plants
    • Sawai, S.; Saito, K. Triterpenoid biosynthesis and engineering in plants. Front. Plant Sci. 2011, 2, 25.
    • (2011) Front. Plant Sci , vol.2 , pp. 25
    • Sawai, S.1    Saito, K.2
  • 55
    • 77953200019 scopus 로고    scopus 로고
    • Genomic and coexpression analyses predict multiple genes involved in triterpene saponin biosynthesis in Medicago truncatula
    • Naoumkina, M.A.; Modolo, L.V.; Huhman, D.V.; Urbanczyk-Wochniak, E.; Tang, Y.H.; Sumner, L.W.; Dixon, R.A. Genomic and coexpression analyses predict multiple genes involved in triterpene saponin biosynthesis in Medicago truncatula. Plant Cell 2010, 22, 850-866.
    • (2010) Plant Cell , vol.22 , pp. 850-866
    • Naoumkina, M.A.1    Modolo, L.V.2    Huhman, D.V.3    Urbanczyk-Wochniak, E.4    Tang, Y.H.5    Sumner, L.W.6    Dixon, R.A.7
  • 57
    • 29244486464 scopus 로고    scopus 로고
    • Functional and structural analysis of genes encoding oxidosqualene cyclases of Lotus japonicus
    • Sawai, S.; Shindo, T.; Sato, S.; Kaneko, T.; Tabata, S.; Ayabe, S.; Aoki, T. Functional and structural analysis of genes encoding oxidosqualene cyclases of Lotus japonicus. Plant Sci. 2006, 170, 247-257.
    • (2006) Plant Sci , vol.170 , pp. 247-257
    • Sawai, S.1    Shindo, T.2    Sato, S.3    Kaneko, T.4    Tabata, S.5    Ayabe, S.6    Aoki, T.7
  • 58
    • 0037356157 scopus 로고    scopus 로고
    • Molecular cloning and characterization of triterpene synthases from Medicago truncatula and Lotus japonicus
    • Iturbe-Ormaetxe, I.; Haralampidis, K.; Papadopoulou, K.; Osbourn, A.E. Molecular cloning and characterization of triterpene synthases from Medicago truncatula and Lotus japonicus. Plant Mol. Biol. 2003, 51, 731-743.
    • (2003) Plant Mol. Biol , vol.51 , pp. 731-743
    • Iturbe-Ormaetxe, I.1    Haralampidis, K.2    Papadopoulou, K.3    Osbourn, A.E.4
  • 60
    • 0034862884 scopus 로고    scopus 로고
    • Cloning and characterization of a cDNA encoding β-amyrin synthase involved in glycyrrhizin and soyasaponin biosyntheses in licorice
    • Hayashi, H.; Huang, P.; Kirakosyan, A.; Inoue, K.; Hiraoka, N.; Ikeshiro, Y.; Kushiro, T.; Shibuya, M.; Ebizuka, Y. Cloning and characterization of a cDNA encoding β-amyrin synthase involved in glycyrrhizin and soyasaponin biosyntheses in licorice. Biol. Pharm. Bull. 2001, 24, 912-916.
    • (2001) Biol. Pharm. Bull , vol.24 , pp. 912-916
    • Hayashi, H.1    Huang, P.2    Kirakosyan, A.3    Inoue, K.4    Hiraoka, N.5    Ikeshiro, Y.6    Kushiro, T.7    Shibuya, M.8    Ebizuka, Y.9
  • 61
    • 78650984754 scopus 로고    scopus 로고
    • Two oxidosqualene cyclases responsible for biosynthesis of tomato fruit cuticular triterpenoids
    • Wang, Z.; Guhling, O.; Yao, R.; Li, F.; Yeats, T.H.; Rose, J.K.C.; Jetter, R. Two oxidosqualene cyclases responsible for biosynthesis of tomato fruit cuticular triterpenoids. Plant Physiol. 2011, 155, 540-552.
    • (2011) Plant Physiol , vol.155 , pp. 540-552
    • Wang, Z.1    Guhling, O.2    Yao, R.3    Li, F.4    Yeats, T.H.5    Rose, J.K.C.6    Jetter, R.7
  • 62
    • 0001031993 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of triterpene synthases from pea (Pisum sativum) new α-amyrin-producing enzyme is a multifunctional triterpene synthase
    • Morita, M.; Shibuya, M.; Kushiro, T.; Masuda, K.; Ebizuka, Y. Molecular cloning and functional expression of triterpene synthases from pea (Pisum sativum) new α-amyrin-producing enzyme is a multifunctional triterpene synthase. Eur. J. Biochem. 2000, 267, 3453-3460.
    • (2000) Eur. J. Biochem , vol.267 , pp. 3453-3460
    • Morita, M.1    Shibuya, M.2    Kushiro, T.3    Masuda, K.4    Ebizuka, Y.5
  • 63
    • 34247267753 scopus 로고    scopus 로고
    • Saponin biosynthesis in Saponaria vaccaria. cDNAs encoding β-amyrin synthase and a triterpene carboxylic acid glucosyltransferase
    • Meesapyodsuk, D.; Balsevich, J.; Reed, D.W.; Covello, P.S. Saponin biosynthesis in Saponaria vaccaria. cDNAs encoding β-amyrin synthase and a triterpene carboxylic acid glucosyltransferase. Plant Physiol. 2007, 143, 959-969.
    • (2007) Plant Physiol , vol.143 , pp. 959-969
    • Meesapyodsuk, D.1    Balsevich, J.2    Reed, D.W.3    Covello, P.S.4
  • 64
    • 2542634233 scopus 로고    scopus 로고
    • A gene cluster for secondary metabolism in oat: Implications for the evolution of metabolic diversity in plants
    • Qi, X.; Bakht, S.; Leggett, M.; Maxwell, C.; Melton, R.; Osbourn, A. A gene cluster for secondary metabolism in oat: implications for the evolution of metabolic diversity in plants. Proc. Natl. Acad. Sci. USA 2004, 101, 8233-8238.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 8233-8238
    • Qi, X.1    Bakht, S.2    Leggett, M.3    Maxwell, C.4    Melton, R.5    Osbourn, A.6
  • 66
    • 0034734610 scopus 로고    scopus 로고
    • A novel multifunctional triterpene synthase from Arabidopsis thaliana
    • Kushiro, T.; Shibuya, M.; Masuda, K.; Ebizuka, Y. A novel multifunctional triterpene synthase from Arabidopsis thaliana. Tetrahedron Lett. 2000, 41, 7705-7710.
    • (2000) Tetrahedron Lett , vol.41 , pp. 7705-7710
    • Kushiro, T.1    Shibuya, M.2    Masuda, K.3    Ebizuka, Y.4
  • 68
    • 0032529028 scopus 로고    scopus 로고
    • β-amyrin synthase. Cloning of oxidosqualene cyclase that catalyzes the formation of the most popular triterpene among higher plants
    • Kushiro, T.; Shibuya, M.; Ebizuka, Y. β-amyrin synthase. Cloning of oxidosqualene cyclase that catalyzes the formation of the most popular triterpene among higher plants. Eur. J. Biochem. 1998, 256, 238-244.
    • (1998) Eur. J. Biochem , vol.256 , pp. 238-244
    • Kushiro, T.1    Shibuya, M.2    Ebizuka, Y.3
  • 69
    • 0035111648 scopus 로고    scopus 로고
    • Molecular cloning and expression in yeast of 2,3-oxidosqualene-triterpenoid cyclases from Arabidopsis thaliana
    • Husselstein-Muller, T.; Schaller, H.; Benveniste, P. Molecular cloning and expression in yeast of 2,3-oxidosqualene-triterpenoid cyclases from Arabidopsis thaliana. Plant Mol. Biol. 2001, 45, 75-92.
    • (2001) Plant Mol. Biol , vol.45 , pp. 75-92
    • Husselstein-Muller, T.1    Schaller, H.2    Benveniste, P.3
  • 70
    • 0033199227 scopus 로고    scopus 로고
    • Cytochrome P450 and the individuality of species
    • Nelson, D.R. Cytochrome P450 and the individuality of species. Arch. Biochem. Biophys. 1999, 369, 1-10.
    • (1999) Arch. Biochem. Biophys , vol.369 , pp. 1-10
    • Nelson, D.R.1
  • 71
    • 79951571893 scopus 로고    scopus 로고
    • Unusual P450 reactions in plant secondary metabolism
    • Mizutani, M.; Sato F. Unusual P450 reactions in plant secondary metabolism. Arch. Biochem. Biophys. 2011, 507, 194-203.
    • (2011) Arch. Biochem. Biophys , vol.507 , pp. 194-203
    • Mizutani, M.1    Sato, F.2
  • 75
    • 84861900283 scopus 로고    scopus 로고
    • Impacts of diversification of cytochrome P450 on plant metabolism
    • Mizutani, M. Impacts of diversification of cytochrome P450 on plant metabolism. Biol. Pharm. Bull. 2012, 35, 824-832.
    • (2012) Biol. Pharm. Bull , vol.35 , pp. 824-832
    • Mizutani, M.1
  • 77
    • 42549088178 scopus 로고    scopus 로고
    • Metabolic diversification-independent assembly of operon-like gene clusters in different plants
    • Field, B.; Osbourn, A.E. Metabolic diversification-independent assembly of operon-like gene clusters in different plants. Science 2008, 320, 543-547.
    • (2008) Science , vol.320 , pp. 543-547
    • Field, B.1    Osbourn, A.E.2
  • 78
    • 68049142239 scopus 로고    scopus 로고
    • Functional genomics of family 1 glycosyltransferases in Arabidopsis
    • Yonekura-Sakakibara, K. Functional genomics of family 1 glycosyltransferases in Arabidopsis. Plant Biotechnol. 2009, 26, 267-274.
    • (2009) Plant Biotechnol , vol.26 , pp. 267-274
    • Yonekura-Sakakibara, K.1
  • 79
    • 27644476269 scopus 로고    scopus 로고
    • Plant secondary metabolism glycosyltransferases: The emerging functional analysis
    • Gachon, C.M.M.; Langlois-Meurinne, M.; Saindrenan, P. Plant secondary metabolism glycosyltransferases: The emerging functional analysis. Trends Plant Sci. 2005, 10, 542-549.
    • (2005) Trends Plant Sci , vol.10 , pp. 542-549
    • Gachon, C.M.M.1    Langlois-Meurinne, M.2    Saindrenan, P.3
  • 80
    • 0028312482 scopus 로고
    • Multiple secondary plant product UDP-glucose glucosyltransferase genes expressed in cassava (Manihot esculenta Crantz) cotyledons
    • Hughes, J.; Hughes, M.A. Multiple secondary plant product UDP-glucose glucosyltransferase genes expressed in cassava (Manihot esculenta Crantz) cotyledons. DNA Seq. 1994, 5, 41-49.
    • (1994) DNA Seq , vol.5 , pp. 41-49
    • Hughes, J.1    Hughes, M.A.2
  • 83
    • 84255163349 scopus 로고    scopus 로고
    • Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers
    • Luo, H.; Sun, C.; Sun, Y.; Wu, Q.; Li, Y.; Song, J.; Niu, Y.; Cheng, X.; Xu, H.; Li, C., et al. Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. BMC Genomics 2011, 12, S5.
    • (2011) BMC Genomics , vol.12
    • Luo, H.1    Sun, C.2    Sun, Y.3    Wu, Q.4    Li, Y.5    Song, J.6    Niu, Y.7    Cheng, X.8    Xu, H.9    Li, C.10
  • 85
    • 33846815083 scopus 로고    scopus 로고
    • Characterization and engineering of glycosyltransferases responsible for steroid saponin biosynthesis in Solanaceous plants
    • Kohara, A.; Nakajima, C.; Yoshida, S.; Muranaka, T. Characterization and engineering of glycosyltransferases responsible for steroid saponin biosynthesis in Solanaceous plants. Phytochemistry 2007, 68, 478-486.
    • (2007) Phytochemistry , vol.68 , pp. 478-486
    • Kohara, A.1    Nakajima, C.2    Yoshida, S.3    Muranaka, T.4
  • 86
    • 79251523542 scopus 로고    scopus 로고
    • Expression and functional characterization of three squalene synthase genes associated with saponin biosynthesis in Panax ginseng
    • Kim, T.D.; Han, J.Y.; Huh, G.H.; Choi, Y.E. Expression and functional characterization of three squalene synthase genes associated with saponin biosynthesis in Panax ginseng. Plant Cell Physiol. 2011, 52, 125-137.
    • (2011) Plant Cell Physiol , vol.52 , pp. 125-137
    • Kim, T.D.1    Han, J.Y.2    Huh, G.H.3    Choi, Y.E.4
  • 87
    • 33846043164 scopus 로고    scopus 로고
    • Upregulation of isoprenoid pathway genes during enhanced saikosaponin biosynthesis in the hairy roots of Bupleurum falcatum
    • Kim, Y.S.; Cho, J.H.; Ahn, J.; Hwang, B. Upregulation of isoprenoid pathway genes during enhanced saikosaponin biosynthesis in the hairy roots of Bupleurum falcatum. Mol. Cells 2006, 22, 269-274.
    • (2006) Mol. Cells , vol.22 , pp. 269-274
    • Kim, Y.S.1    Cho, J.H.2    Ahn, J.3    Hwang, B.4
  • 88
    • 0033377995 scopus 로고    scopus 로고
    • Meristem-localized inducible expression of a UDP-glycosyltransferase gene is essential for growth and development in pea and alfalfa
    • Woo, H.H.; Orbach, M.J.; Hirsch, A.M.; Hawes, M.C. Meristem-localized inducible expression of a UDP-glycosyltransferase gene is essential for growth and development in pea and alfalfa. Plant Cell 1999, 11, 2303-2315.
    • (1999) Plant Cell , vol.11 , pp. 2303-2315
    • Woo, H.H.1    Orbach, M.J.2    Hirsch, A.M.3    Hawes, M.C.4
  • 89
    • 14544307566 scopus 로고    scopus 로고
    • A red beet (Beta vulgaris) UDP-glucosyltransferase gene induced by wounding, bacterial infiltration and oxidative stress
    • Sepúlveda-Jiménez, G.; Rueda-Benítez, P.; Porta, H.; Rocha-Sosa, M. A red beet (Beta vulgaris) UDP-glucosyltransferase gene induced by wounding, bacterial infiltration and oxidative stress. J. Exp. Bot. 2005, 56, 605-611.
    • (2005) J. Exp. Bot , vol.56 , pp. 605-611
    • Sepúlveda-Jiménez, G.1    Rueda-Benítez, P.2    Porta, H.3    Rocha-Sosa, M.4
  • 90
    • 82755176592 scopus 로고    scopus 로고
    • The transcription factor CrWRKY1 positively regulates the terpenoid indole alkaloid biosynthesis in Catharanthus roseus
    • Suttipanta, N.; Pattanaik, S.; Kulshrestha, M.; Patra, B.; Singh, S.K.; Yuan, L. The transcription factor CrWRKY1 positively regulates the terpenoid indole alkaloid biosynthesis in Catharanthus roseus. Plant Physiol. 2011, 157, 2081-2093.
    • (2011) Plant Physiol , vol.157 , pp. 2081-2093
    • Suttipanta, N.1    Pattanaik, S.2    Kulshrestha, M.3    Patra, B.4    Singh, S.K.5    Yuan, L.6
  • 91
    • 33745093748 scopus 로고    scopus 로고
    • DOF transcription factor AtDof1.1 (OBP2) is part of a regulatory network controlling glucosinolate biosynthesis in Arabidopsis
    • Skirycz, A.; Reichelt, M.; Burow, M.; Birkemeyer, C.; Rolcik, J.; Kopka, J.; Zanor, M.I.; Gershenzon, J.; Strnad, M.; Szopa, J., et al. DOF transcription factor AtDof1.1 (OBP2) is part of a regulatory network controlling glucosinolate biosynthesis in Arabidopsis. Plant J. 2006, 47, 10-24.
    • (2006) Plant J , vol.47 , pp. 10-24
    • Skirycz, A.1    Reichelt, M.2    Burow, M.3    Birkemeyer, C.4    Rolcik, J.5    Kopka, J.6    Zanor, M.I.7    Gershenzon, J.8    Strnad, M.9    Szopa, J.10
  • 93
    • 0037297787 scopus 로고    scopus 로고
    • OsDREB genes in rice, Oryza sativa L., encode transcription activators that function in drought-, high-salt- and cold-responsive gene expression
    • Dubouzet, J.G.; Sakuma, Y.; Ito, Y.; Kasuga, M.; Dubouzet, E.G.; Miura, S.; Seki, M.; Shinozaki, K.; Yamaguchi-Shinozaki, K. OsDREB genes in rice, Oryza sativa L., encode transcription activators that function in drought-, high-salt- and cold-responsive gene expression. Plant J. 2003, 33, 751-763.
    • (2003) Plant J , vol.33 , pp. 751-763
    • Dubouzet, J.G.1    Sakuma, Y.2    Ito, Y.3    Kasuga, M.4    Dubouzet, E.G.5    Miura, S.6    Seki, M.7    Shinozaki, K.8    Yamaguchi-Shinozaki, K.9
  • 94
    • 33646832415 scopus 로고    scopus 로고
    • Genome-wide analysis of the ERF gene family in Arabidopsis and rice
    • Nakano, T.; Suzuki, K.; Fujimura, T.; Shinshi, H. Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol. 2006, 140, 411-432.
    • (2006) Plant Physiol , vol.140 , pp. 411-432
    • Nakano, T.1    Suzuki, K.2    Fujimura, T.3    Shinshi, H.4
  • 95
    • 78651437404 scopus 로고    scopus 로고
    • Functional characterization of three ethylene response factor genes from Bupleurum kaoi indicates that BkERFs mediate resistance to Botrytis cinerea
    • Liu, W.Y.; Chiou, S.J.; Ko, C.Y.; Lin, T.Y. Functional characterization of three ethylene response factor genes from Bupleurum kaoi indicates that BkERFs mediate resistance to Botrytis cinerea. J. Plant Physiol. 2011, 168, 375-381.
    • (2011) J. Plant Physiol , vol.168 , pp. 375-381
    • Liu, W.Y.1    Chiou, S.J.2    Ko, C.Y.3    Lin, T.Y.4
  • 96
    • 0029240488 scopus 로고
    • Ethylene-inducible DNA binding proteins that interact with an ethylene-responsive element
    • Ohme-Takagi, M.; Shinshi, H. Ethylene-inducible DNA binding proteins that interact with an ethylene-responsive element. Plant Cell 1995, 7, 173-182.
    • (1995) Plant Cell , vol.7 , pp. 173-182
    • Ohme-Takagi, M.1    Shinshi, H.2
  • 97
    • 0035999378 scopus 로고    scopus 로고
    • Tomato transcription factors pti4, pti5, and pti6 activate defense responses when expressed in Arabidopsis
    • Gu, Y.Q.; Wildermuth, M.C.; Chakravarthy, S.; Loh, Y.T.; Yang, C.; He, X.; Han, Y.; Martin, G.B. Tomato transcription factors pti4, pti5, and pti6 activate defense responses when expressed in Arabidopsis. Plant Cell 2002, 14, 817-831.
    • (2002) Plant Cell , vol.14 , pp. 817-831
    • Gu, Y.Q.1    Wildermuth, M.C.2    Chakravarthy, S.3    Loh, Y.T.4    Yang, C.5    He, X.6    Han, Y.7    Martin, G.B.8
  • 98
    • 16644380820 scopus 로고    scopus 로고
    • Overexpression of the AP2/EREBP transcription factor OPBP1 enhances disease resistance and salt tolerance in tobacco
    • Guo, Z.J.; Chen, X.J.; Wu, X.L.; Ling, J.Q.; Xu, P. Overexpression of the AP2/EREBP transcription factor OPBP1 enhances disease resistance and salt tolerance in tobacco. Plant Mol. Biol. 2004, 55, 607-618.
    • (2004) Plant Mol. Biol , vol.55 , pp. 607-618
    • Guo, Z.J.1    Chen, X.J.2    Wu, X.L.3    Ling, J.Q.4    Xu, P.5
  • 99
    • 0037259469 scopus 로고    scopus 로고
    • ETHYLENE RESPONSE FACTOR1 integrates signals from ethylene and jasmonate pathways in plant defense
    • Lorenzo, O.; Piqueras, R.; Sanchez-Serrano, J.J.; Solano, R. ETHYLENE RESPONSE FACTOR1 integrates signals from ethylene and jasmonate pathways in plant defense. Plant Cell 2003, 15, 165-178.
    • (2003) Plant Cell , vol.15 , pp. 165-178
    • Lorenzo, O.1    Piqueras, R.2    Sanchez-Serrano, J.J.3    Solano, R.4
  • 100
    • 33644655130 scopus 로고    scopus 로고
    • Repressor-and activator-type ethylene response factors functioning in jasmonate signaling and disease resistance identified via a genome-wide screen of Arabidopsis transcription factor gene expression
    • McGrath, K.C.; Dombrecht, B.; Manners, J.M.; Schenk, P.M.; Edgar, C.I.; Maclean, D.J.; Scheible, W.R.; Udvardi, M.K.; Kazan, K. Repressor-and activator-type ethylene response factors functioning in jasmonate signaling and disease resistance identified via a genome-wide screen of Arabidopsis transcription factor gene expression. Plant Physiol. 2005, 139, 949-959.
    • (2005) Plant Physiol , vol.139 , pp. 949-959
    • McGrath, K.C.1    Dombrecht, B.2    Manners, J.M.3    Schenk, P.M.4    Edgar, C.I.5    Maclean, D.J.6    Scheible, W.R.7    Udvardi, M.K.8    Kazan, K.9
  • 101
    • 0036007581 scopus 로고    scopus 로고
    • Constitutive expression of ETHYLENE-RESPONSE-FACTOR1 in Arabidopsis confers resistance to several necrotrophic fungi
    • Berrocal-Lobo, M.; Molina, A.; Solano, R. Constitutive expression of ETHYLENE-RESPONSE-FACTOR1 in Arabidopsis confers resistance to several necrotrophic fungi. Plant J. 2002, 29, 23-32.
    • (2002) Plant J , vol.29 , pp. 23-32
    • Berrocal-Lobo, M.1    Molina, A.2    Solano, R.3
  • 102
    • 51549112366 scopus 로고    scopus 로고
    • The AP2/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense
    • Pre, M.; Atallah, M.; Champion, A.; de Vos, M.; Pieterse, C.M.; Memelink, J. The AP2/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense. Plant Physiol. 2008, 147, 1347-1357.
    • (2008) Plant Physiol , vol.147 , pp. 1347-1357
    • Pre, M.1    Atallah, M.2    Champion, A.3    de Vos, M.4    Pieterse, C.M.5    Memelink, J.6
  • 103
    • 84876775560 scopus 로고    scopus 로고
    • Phosphorylation of an ERF transcription factor by Arabidopsis MPK3/MPK6 regulates plant defense gene induction and fungal resistance
    • Meng, X.; Xu, J.; He, Y.; Yang, K.Y.; Mordorski, B.; Liu, Y.; Zhang, S. Phosphorylation of an ERF transcription factor by Arabidopsis MPK3/MPK6 regulates plant defense gene induction and fungal resistance. Plant Cell 2013, 25, 1126-1142.
    • (2013) Plant Cell , vol.25 , pp. 1126-1142
    • Meng, X.1    Xu, J.2    He, Y.3    Yang, K.Y.4    Mordorski, B.5    Liu, Y.6    Zhang, S.7
  • 104
    • 84859128468 scopus 로고    scopus 로고
    • The jasmonate-responsive AP2/ERF transcription factors AaERF1 and AaERF2 positively regulate artemisinin biosynthesis in Artemisia annua L
    • Yu, Z.X.; Li, J.X.; Yang, C.Q.; Hu, W.L.; Wang, L.J.; Chen, X.Y. The jasmonate-responsive AP2/ERF transcription factors AaERF1 and AaERF2 positively regulate artemisinin biosynthesis in Artemisia annua L. Mol. Plant 2012, 5, 353-365.
    • (2012) Mol. Plant , vol.5 , pp. 353-365
    • Yu, Z.X.1    Li, J.X.2    Yang, C.Q.3    Hu, W.L.4    Wang, L.J.5    Chen, X.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.