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Volumn 12, Issue 6, 2013, Pages 1099-1111

Bisphosphorylated PEA-15 sensitizes ovarian cancer cells to paclitaxel by impairing the microtubule-destabilizing effect of SCLIP

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; PACLITAXEL; PHOSPHOPROTEIN; PHOSPHOPROTEIN ENRICHED IN ASTROCYTES 15; UNCLASSIFIED DRUG;

EID: 84879295434     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-12-0737     Document Type: Article
Times cited : (15)

References (44)
  • 2
    • 84869093022 scopus 로고    scopus 로고
    • Engineering Macaca fascicularis cytochrome P450 2C20 to reduce animal testing for new drugs
    • Rua F, Sadeghi SJ, Castrignano S, Di Nardo G, Gilardi G. Engineering Macaca fascicularis cytochrome P450 2C20 to reduce animal testing for new drugs. J Inorg Biochem 2012;117:277-84.
    • (2012) J Inorg Biochem , vol.117 , pp. 277-284
    • Rua, F.1    Sadeghi, S.J.2    Castrignano, S.3    Di Nardo, G.4    Gilardi, G.5
  • 4
    • 0019859353 scopus 로고
    • Taxol binds to polymerized tubulin in vitro
    • Parness J, Horwitz SB. Taxol binds to polymerized tubulin in vitro. J Cell Biol 1981;91:479-87.
    • (1981) J Cell Biol , vol.91 , pp. 479-487
    • Parness, J.1    Horwitz, S.B.2
  • 5
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan MA, Wilson L. Microtubules as a target for anticancer drugs. Nat Rev Cancer 2004;4:253-65.
    • (2004) Nat Rev Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 6
    • 0032933622 scopus 로고    scopus 로고
    • Taxol suppresses dynamics of individual microtubules in living human tumor cells
    • Yvon AM, Wadsworth P, Jordan MA. Taxol suppresses dynamics of individual microtubules in living human tumor cells. Mol Biol Cell 1999;10:947-59.
    • (1999) Mol Biol Cell , vol.10 , pp. 947-959
    • Yvon, A.M.1    Wadsworth, P.2    Jordan, M.A.3
  • 7
    • 34548237539 scopus 로고    scopus 로고
    • Novel agents in ovarian cancer
    • Matei D. Novel agents in ovarian cancer. Expert Opin Investig Drugs 2007;16:1227-39.
    • (2007) Expert Opin Investig Drugs , vol.16 , pp. 1227-1239
    • Matei, D.1
  • 9
    • 5644269048 scopus 로고    scopus 로고
    • Fluoxetine inhibits multidrug resistance extrusion pumps and enhances responses to chemotherapy in syngeneic and in human xenograft mouse tumor models
    • Peer D, Dekel Y, Melikhov D, Margalit R. Fluoxetine inhibits multidrug resistance extrusion pumps and enhances responses to chemotherapy in syngeneic and in human xenograft mouse tumor models. Cancer Res 2004;64:7562-9.
    • (2004) Cancer Res , vol.64 , pp. 7562-7569
    • Peer, D.1    Dekel, Y.2    Melikhov, D.3    Margalit, R.4
  • 10
    • 18444379938 scopus 로고    scopus 로고
    • Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis
    • Tan M, Jing T, Lan KH, Neal CL, Li P, Lee S, et al. Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis. Mol Cell 2002; 9:993-1004.
    • (2002) Mol Cell , vol.9 , pp. 993-1004
    • Tan, M.1    Jing, T.2    Lan, K.H.3    Neal, C.L.4    Li, P.5    Lee, S.6
  • 11
    • 0030758777 scopus 로고    scopus 로고
    • Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization
    • Giannakakou P, Sackett DL, Kang YK, Zhan Z, Buters JT, Fojo T, et al. Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization. J Biol Chem 1997;272:17118-25.
    • (1997) J Biol Chem , vol.272 , pp. 17118-17125
    • Giannakakou, P.1    Sackett, D.L.2    Kang, Y.K.3    Zhan, Z.4    Buters, J.T.5    Fojo, T.6
  • 12
    • 77249130649 scopus 로고    scopus 로고
    • Glycoproteomics of paclitaxel resistance in human epithelial ovarian cancer cell lines: Towards the identification of putative bio-markers
    • Di Michele M, Marcone S, Cicchillitti L, Della Corte A, Ferlini C, Scambia G, et al. Glycoproteomics of paclitaxel resistance in human epithelial ovarian cancer cell lines: towards the identification of putative bio-markers. J Proteomics 2010;73:879-98.
    • (2010) J Proteomics , vol.73 , pp. 879-898
    • Di Michele, M.1    Marcone, S.2    Cicchillitti, L.3    Della Corte, A.4    Ferlini, C.5    Scambia, G.6
  • 13
    • 56449116341 scopus 로고    scopus 로고
    • PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival
    • Bartholomeusz C, Rosen D, Wei C, Kazansky A, Yamasaki F, Takahashi T, et al. PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival. Cancer Res 2008; 68:9302-10.
    • (2008) Cancer Res , vol.68 , pp. 9302-9310
    • Bartholomeusz, C.1    Rosen, D.2    Wei, C.3    Kazansky, A.4    Yamasaki, F.5    Takahashi, T.6
  • 14
    • 77949748262 scopus 로고    scopus 로고
    • PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase
    • Bartholomeusz C, Gonzalez-Angulo AM, Kazansky A, Krishnamurthy S, Liu P, Yuan LX, et al. PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase. Clin Cancer Res 2010;16:1802-11.
    • (2010) Clin Cancer Res , vol.16 , pp. 1802-1811
    • Bartholomeusz, C.1    Gonzalez-Angulo, A.M.2    Kazansky, A.3    Krishnamurthy, S.4    Liu, P.5    Yuan, L.X.6
  • 15
    • 33847759815 scopus 로고    scopus 로고
    • PEA-15 inhibits tumor cell invasion by binding to extracellular signal-regulated kinase 1/2
    • Glading A, Koziol JA, Krueger J, Ginsberg MH. PEA-15 inhibits tumor cell invasion by binding to extracellular signal-regulated kinase 1/2. Cancer Res 2007;67:1536-44.
    • (2007) Cancer Res , vol.67 , pp. 1536-1544
    • Glading, A.1    Koziol, J.A.2    Krueger, J.3    Ginsberg, M.H.4
  • 16
    • 69049103284 scopus 로고    scopus 로고
    • Frontiers: Ped/PEA-15, a multifunctional protein controlling cell survival and glucose metabolism
    • Fiory F, Formisano P, Perruolo G, Beguinot F. Frontiers: PED/PEA-15, a multifunctional protein controlling cell survival and glucose metabolism. Am J Physiol Endocrinol Metab 2009;297: E592-601.
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Fiory, F.1    Formisano, P.2    Perruolo, G.3    Beguinot, F.4
  • 17
    • 23044493865 scopus 로고    scopus 로고
    • Phosphor-ylation of phosphoprotein enriched in astrocytes (PEA-15) regulates extracellular signal-regulated kinase-dependent transcription and cell proliferation
    • Krueger J, Chou FL, Glading A, Schaefer E, Ginsberg MH. Phosphor-ylation of phosphoprotein enriched in astrocytes (PEA-15) regulates extracellular signal-regulated kinase-dependent transcription and cell proliferation. Mol Biol Cell 2005;16:3552-61.
    • (2005) Mol Biol Cell , vol.16 , pp. 3552-3561
    • Krueger, J.1    Chou, F.L.2    Glading, A.3    Schaefer, E.4    Ginsberg, M.H.5
  • 18
    • 84864350270 scopus 로고    scopus 로고
    • PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D
    • Sulzmaier FJ, Valmiki MK, Nelson DA, Caliva MJ, Geerts D, Matter ML, et al. PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D. Oncogene 2012;31:3547-60.
    • (2012) Oncogene , vol.31 , pp. 3547-3560
    • Sulzmaier, F.J.1    Valmiki, M.K.2    Nelson, D.A.3    Caliva, M.J.4    Geerts, D.5    Matter, M.L.6
  • 19
    • 0031819445 scopus 로고    scopus 로고
    • Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: Identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II in vitro
    • Kubes M, Cordier J, Glowinski J, Girault JA, Chneiweiss H. Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II in vitro. J Neurochem 1998;71:1307-14.
    • (1998) J Neurochem , vol.71 , pp. 1307-1314
    • Kubes, M.1    Cordier, J.2    Glowinski, J.3    Girault, J.A.4    Chneiweiss, H.5
  • 20
    • 0038721240 scopus 로고    scopus 로고
    • Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action
    • Trencia A, Perfetti A, Cassese A, Vigliotta G, Miele C, Oriente F, et al. Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action. Mol Cell Biol 2003;23:4511-21.
    • (2003) Mol Cell Biol , vol.23 , pp. 4511-4521
    • Trencia, A.1    Perfetti, A.2    Cassese, A.3    Vigliotta, G.4    Miele, C.5    Oriente, F.6
  • 22
    • 0036468982 scopus 로고    scopus 로고
    • The oncoprotein 18/stathmin family of microtubule destabilizers
    • Cassimeris L. The oncoprotein 18/stathmin family of microtubule destabilizers. Curr Opin Cell Biol 2002;14:18-24.
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 18-24
    • Cassimeris, L.1
  • 23
    • 0035844234 scopus 로고    scopus 로고
    • Stathmin family proteins display specific molecular and tubulin binding properties
    • Charbaut E, Curmi PA, Ozon S, Lachkar S, Redeker V, Sobel A. Stathmin family proteins display specific molecular and tubulin binding properties. J Biol Chem 2001;276:16146-54.
    • (2001) J Biol Chem , vol.276 , pp. 16146-16154
    • Charbaut, E.1    Curmi, P.A.2    Ozon, S.3    Lachkar, S.4    Redeker, V.5    Sobel, A.6
  • 24
    • 0030048731 scopus 로고    scopus 로고
    • Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules
    • Belmont LD, Mitchison TJ. Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules. Cell 1996;84:623-31.
    • (1996) Cell , vol.84 , pp. 623-631
    • Belmont, L.D.1    Mitchison, T.J.2
  • 25
    • 33644862731 scopus 로고    scopus 로고
    • Stathmin strongly increases the minus end catastrophe frequency and induces rapid treadmilling of bovine brain microtubules at steady state in vitro
    • Manna T, Thrower D, Miller HP, Curmi P, Wilson L. Stathmin strongly increases the minus end catastrophe frequency and induces rapid treadmilling of bovine brain microtubules at steady state in vitro. J Biol Chem 2006;281:2071-8.
    • (2006) J Biol Chem , vol.281 , pp. 2071-2078
    • Manna, T.1    Thrower, D.2    Miller, H.P.3    Curmi, P.4    Wilson, L.5
  • 26
    • 0031745447 scopus 로고    scopus 로고
    • The stathmin phosphoprotein family: Intracellular localization and effects on the microtubule network
    • Gavet O, Ozon S, Manceau V, Lawler S, Curmi P, Sobel A. The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network. J Cell Sci 1998;111:3333-46.
    • (1998) J Cell Sci , vol.111 , pp. 3333-3346
    • Gavet, O.1    Ozon, S.2    Manceau, V.3    Lawler, S.4    Curmi, P.5    Sobel, A.6
  • 27
    • 0036897325 scopus 로고    scopus 로고
    • Effect of stathmin on the sensitivity to antimicrotubule drugs in human breast cancer
    • Alli E, Bash-Babula J, Yang JM, Hait WN. Effect of stathmin on the sensitivity to antimicrotubule drugs in human breast cancer. Cancer Res 2002;62:6864-9.
    • (2002) Cancer Res , vol.62 , pp. 6864-6869
    • Alli, E.1    Bash-Babula, J.2    Yang, J.M.3    Hait, W.N.4
  • 28
    • 84868282628 scopus 로고    scopus 로고
    • PEA-15 unphosphorylated at both serine 104 and serine 116 inhibits ovarian cancer cell tumorigenicity and progression through blocking b-catenin
    • Lee J, Bartholomeusz C, Krishnamurthy S, Liu P, Saso H, LaFortune T, et al. PEA-15 unphosphorylated at both serine 104 and serine 116 inhibits ovarian cancer cell tumorigenicity and progression through blocking b-catenin. Oncogenesis 2012;1:e22.
    • (2012) Oncogenesis , vol.1
    • Lee, J.1    Bartholomeusz, C.2    Krishnamurthy, S.3    Liu, P.4    Saso, H.5    LaFortune, T.6
  • 29
    • 36749012914 scopus 로고    scopus 로고
    • Persistent use of "false" cell lines
    • Lacroix M. Persistent use of "false" cell lines. Int J Cancer 2008;122: 1-4.
    • (2008) Int J Cancer , vol.122 , pp. 1-4
    • Lacroix, M.1
  • 30
    • 79961160941 scopus 로고    scopus 로고
    • Synthesis and antitumor efficacy of daunorubicin-loaded magnetic nanoparticles
    • Wang J, Chen B, Chen J, Cai X, Xia G, Liu R, et al. Synthesis and antitumor efficacy of daunorubicin-loaded magnetic nanoparticles. Int J Nanomedicine 2011;6:203-11.
    • (2011) Int J Nanomedicine , vol.6 , pp. 203-211
    • Wang, J.1    Chen, B.2    Chen, J.3    Cai, X.4    Xia, G.5    Liu, R.6
  • 31
    • 34247468422 scopus 로고    scopus 로고
    • Reversal of stathmin-mediated resistance to paclitaxel and vinblastine in human breast carcinoma cells
    • Alli E, Yang JM, Ford JM, Hait WN. Reversal of stathmin-mediated resistance to paclitaxel and vinblastine in human breast carcinoma cells. Mol Pharmacol 2007;71:1233-40.
    • (2007) Mol Pharmacol , vol.71 , pp. 1233-1240
    • Alli, E.1    Yang, J.M.2    Ford, J.M.3    Hait, W.N.4
  • 33
    • 34547446548 scopus 로고    scopus 로고
    • Mitotic index determination by flow cytometry
    • Gillespie DA, Walker M. Mitotic index determination by flow cytometry. Subcell Biochem 2006;40:355-8.
    • (2006) Subcell Biochem , vol.40 , pp. 355-358
    • Gillespie, D.A.1    Walker, M.2
  • 35
    • 0027360552 scopus 로고
    • Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations
    • Jordan MA, Toso RJ, Thrower D, Wilson L. Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc Natl Acad Sci U S A 1993;90:9552-6.
    • (1993) Proc Natl Acad Sci u S A , vol.90 , pp. 9552-9556
    • Jordan, M.A.1    Toso, R.J.2    Thrower, D.3    Wilson, L.4
  • 36
    • 0034665140 scopus 로고    scopus 로고
    • Taxol mediates serine phosphorylation of the 66-kDa Shc isoform
    • Yang CP, Horwitz SB. Taxol mediates serine phosphorylation of the 66-kDa Shc isoform. Cancer Res 2000;60:5171-8.
    • (2000) Cancer Res , vol.60 , pp. 5171-5178
    • Yang, C.P.1    Horwitz, S.B.2
  • 37
    • 0018104825 scopus 로고
    • Capability of tubulin and microtubules to incorporate and to release tyrosine and phenylalanine and the effect of the incorporation of these amino acids on tubulin assembly
    • Arce CA, Hallak ME, Rodriguez JA, Barra HS, Caputto R. Capability of tubulin and microtubules to incorporate and to release tyrosine and phenylalanine and the effect of the incorporation of these amino acids on tubulin assembly. J Neurochem 1978;31:205-10.
    • (1978) J Neurochem , vol.31 , pp. 205-210
    • Arce, C.A.1    Hallak, M.E.2    Rodriguez, J.A.3    Barra, H.S.4    Caputto, R.5
  • 38
    • 0023389780 scopus 로고
    • Identification of an acetylation site of Chlamydomonas alpha-tubulin
    • LeDizet M, Piperno G. Identification of an acetylation site of Chlamydomonas alpha-tubulin. Proc Natl Acad Sci U S A 1987; 84:5720-4.
    • (1987) Proc Natl Acad Sci u S A , vol.84 , pp. 5720-5724
    • LeDizet, M.1    Piperno, G.2
  • 39
    • 0024593690 scopus 로고
    • Dynamics of alpha-tubulin dea-cetylation in intact neurons
    • Black MM, Baas PW, Humphries S. Dynamics of alpha-tubulin dea-cetylation in intact neurons. J Neurosci 1989;9:358-68.
    • (1989) J Neurosci , vol.9 , pp. 358-368
    • Black, M.M.1    Baas, P.W.2    Humphries, S.3
  • 40
    • 0023371190 scopus 로고
    • Postpolymerization detyro-sination of alpha-tubulin: A mechanism for subcellular differentiation of microtubules
    • Gundersen GG, Khawaja S, Bulinski JC. Postpolymerization detyro-sination of alpha-tubulin: a mechanism for subcellular differentiation of microtubules. J Cell Biol 1987;105:251-64.
    • (1987) J Cell Biol , vol.105 , pp. 251-264
    • Gundersen, G.G.1    Khawaja, S.2    Bulinski, J.C.3
  • 41
    • 0032740020 scopus 로고    scopus 로고
    • The phosphoprotein protein PEA-15 inhibits Fasbut increases TNF-R1-mediated caspase-8 activity and apoptosis
    • Estelles A, Charlton CA, Blau HM. The phosphoprotein protein PEA-15 inhibits Fasbut increases TNF-R1-mediated caspase-8 activity and apoptosis. Dev Biol 1999;216:16-28.
    • (1999) Dev Biol , vol.216 , pp. 16-28
    • Estelles, A.1    Charlton, C.A.2    Blau, H.M.3
  • 42
    • 80052245462 scopus 로고    scopus 로고
    • Modulating microtubule stability enhances the cytotoxic response of cancer cells to Paclitaxel
    • Ahmed AA, Wang X, Lu Z, Goldsmith J, Le XF, Grandjean G, et al. Modulating microtubule stability enhances the cytotoxic response of cancer cells to Paclitaxel. Cancer Res 2011;71:5806-17.
    • (2011) Cancer Res , vol.71 , pp. 5806-5817
    • Ahmed, A.A.1    Wang, X.2    Lu, Z.3    Goldsmith, J.4    Le, X.F.5    Grandjean, G.6
  • 43
    • 0030783012 scopus 로고    scopus 로고
    • Stathmin: A tubulin-sequestering protein which forms a ternary T2S complex with two tubulin molecules
    • Jourdain L, Curmi P, Sobel A, Pantaloni D, Carlier MF. Stathmin: a tubulin-sequestering protein which forms a ternary T2S complex with two tubulin molecules. Biochemistry 1997;36:10817-21.
    • (1997) Biochemistry , vol.36 , pp. 10817-10821
    • Jourdain, L.1    Curmi, P.2    Sobel, A.3    Pantaloni, D.4    Carlier, M.F.5
  • 44
    • 0347994021 scopus 로고    scopus 로고
    • Altered levels and regulation of stathmin in paclitaxel-resistant ovarian cancer cells
    • Balachandran R, Welsh MJ, Day BW. Altered levels and regulation of stathmin in paclitaxel-resistant ovarian cancer cells. Oncogene 2003; 22:8924-30.
    • (2003) Oncogene , vol.22 , pp. 8924-8930
    • Balachandran, R.1    Welsh, M.J.2    Day, B.W.3


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