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Volumn 5, Issue 3, 2013, Pages 169-181

Immunotherapeutic approaches in triple-negative breast cancer: Latest research and clinical prospects

Author keywords

basal like; breast cancer; immunotherapy; T cell

Indexed keywords

5' NUCLEOTIDASE; ANTHRACYCLINE; ANTIGEN; ARGININE; CALRETICULIN; CD134 ANTIGEN; CD137 ANTIGEN; CD27 ANTIGEN; CD30 ANTIGEN; CYTOTOXIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; EPITOPE; ESTROGEN RECEPTOR; IMMUNOGLOBULIN; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; INTERFERON; INTERLEUKIN 8; MESOTHELIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OX40 LIGAND; PLATELET DERIVED GROWTH FACTOR; PROGESTERONE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR VACCINE; WNT PROTEIN;

EID: 84879288623     PISSN: 17588340     EISSN: 17588359     Source Type: Journal    
DOI: 10.1177/1758834012475152     Document Type: Review
Times cited : (144)

References (90)
  • 1
    • 84863008358 scopus 로고    scopus 로고
    • NY-ESO-1 cancer testis antigen demonstrates high immunogenicity in triple negative breast cancer
    • Ademuyiwa F. Bshara W. Attwood K. Morrison C. Edge S. Ambrosone C. et al. (2012) NY-ESO-1 cancer testis antigen demonstrates high immunogenicity in triple negative breast cancer. PloS ONE 7: e38783.
    • (2012) PloS ONE , vol.7 , pp. e38783
    • Ademuyiwa, F.1    Bshara, W.2    Attwood, K.3    Morrison, C.4    Edge, S.5    Ambrosone, C.6
  • 2
    • 79953783229 scopus 로고    scopus 로고
    • The prognostic contribution of clinical breast cancer subtype, age, and race among patients with breast cancer brain metastases
    • Anders C. Deal A. Miller C. Khorram C. Meng H. Burrows E. et al. (2011) The prognostic contribution of clinical breast cancer subtype, age, and race among patients with breast cancer brain metastases. Cancer 117: 1602–1611.
    • (2011) Cancer , vol.117 , pp. 1602-1611
    • Anders, C.1    Deal, A.2    Miller, C.3    Khorram, C.4    Meng, H.5    Burrows, E.6
  • 3
    • 20344377896 scopus 로고    scopus 로고
    • Placental cadherin and the basal epithelial phenotype of BRCA1-related breast cancer
    • Arnes J. Brunet J. Stefansson I. Bégin L. Wong N. Chappuis P. et al. (2005) Placental cadherin and the basal epithelial phenotype of BRCA1-related breast cancer. Clin Cancer Res 11: 4003–4011.
    • (2005) Clin Cancer Res , vol.11 , pp. 4003-4011
    • Arnes, J.1    Brunet, J.2    Stefansson, I.3    Bégin, L.4    Wong, N.5    Chappuis, P.6
  • 4
    • 34247569300 scopus 로고    scopus 로고
    • Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype
    • Bauer K. Brown M. Cress R. Parise C. Caggiano V. (2007) Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype. Cancer 109: 1721–1728.
    • (2007) Cancer , vol.109 , pp. 1721-1728
    • Bauer, K.1    Brown, M.2    Cress, R.3    Parise, C.4    Caggiano, V.5
  • 6
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti–PD-L1 antibody in patients with advanced cancer
    • Brahmer J. Tykodi S. Chow L. Hwu W. Topalian S. Hwu P. et al. (2012) Safety and activity of anti–PD-L1 antibody in patients with advanced cancer. N Engl J Med 366: 2455–2465.
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.1    Tykodi, S.2    Chow, L.3    Hwu, W.4    Topalian, S.5    Hwu, P.6
  • 7
    • 0033564363 scopus 로고    scopus 로고
    • Identification of HLA-A2–restricted T-cell epitopes derived from the MUC 1 tumor antigen for broadly applicable vaccine therapies
    • Brossart P. Heinrich K. Stuhler G. Behnke L. Reichardt V. Stevanovic S. et al. (1999) Identification of HLA-A2–restricted T-cell epitopes derived from the MUC 1 tumor antigen for broadly applicable vaccine therapies. Blood 93: 4309–4317.
    • (1999) Blood , vol.93 , pp. 4309-4317
    • Brossart, P.1    Heinrich, K.2    Stuhler, G.3    Behnke, L.4    Reichardt, V.5    Stevanovic, S.6
  • 8
    • 77957110787 scopus 로고    scopus 로고
    • Prognosis and adjuvant treatment effects in selected breast cancer subtypes of very young women (<35 years) with operable breast cancer
    • Cancello G. Maisonneuve P. Rotmensz N. Viale G. Mastropasqua M. Pruneri G. et al. (2010) Prognosis and adjuvant treatment effects in selected breast cancer subtypes of very young women (<35 years) with operable breast cancer. Ann Oncol 21:1974–1981.
    • (2010) Ann Oncol , vol.21 , pp. 1974-1981
    • Cancello, G.1    Maisonneuve, P.2    Rotmensz, N.3    Viale, G.4    Mastropasqua, M.5    Pruneri, G.6
  • 9
    • 33744960226 scopus 로고    scopus 로고
    • Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
    • Carey L. (2006) Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA 295: 2492–2502.
    • (2006) JAMA , vol.295 , pp. 2492-2502
    • Carey, L.1
  • 10
    • 40949121882 scopus 로고    scopus 로고
    • Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype
    • Cheang M. Voduc D. Bajdik C. Leung S. McKinney S. Chia S. et al. (2008) Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype. Clin Cancer Res 14: 1368–1376.
    • (2008) Clin Cancer Res , vol.14 , pp. 1368-1376
    • Cheang, M.1    Voduc, D.2    Bajdik, C.3    Leung, S.4    McKinney, S.5    Chia, S.6
  • 11
    • 62449309334 scopus 로고    scopus 로고
    • Anti-CTLA-4 therapy results in higher CD4+ICOShi T cell frequency and IFN-γ levels in both nonmalignant and malignant prostate tissues
    • Chen H. Liakou C. Kamat A. Pettaway C. Ward J. Tang D. et al. (2009) Anti-CTLA-4 therapy results in higher CD4+ICOShi T cell frequency and IFN-γ levels in both nonmalignant and malignant prostate tissues. Proc Natl Acad Sci 106: 2729–2734.
    • (2009) Proc Natl Acad Sci , vol.106 , pp. 2729-2734
    • Chen, H.1    Liakou, C.2    Kamat, A.3    Pettaway, C.4    Ward, J.5    Tang, D.6
  • 12
    • 79952785519 scopus 로고    scopus 로고
    • Multiple cancer / testis antigens are preferentially expressed in hormone-receptor negative and high-grade breast cancers
    • Chen Y. Ross D. Chiu R. Zhou X. Chen Y. Lee P. et al. (2011) Multiple cancer / testis antigens are preferentially expressed in hormone-receptor negative and high-grade breast cancers. PloS ONE 6: e17876.
    • (2011) PloS ONE , vol.6 , pp. e17876
    • Chen, Y.1    Chen, Y.2    Ross, D.3    Chiu, R.4    Zhou, X.5    Lee, P.6
  • 13
    • 84865422909 scopus 로고    scopus 로고
    • Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1
    • July (Epub ahead of print).
    • Chiba S. Baghdadi M. Akiba H. Yoshiyama H. Kinoshita I. Dosaka-Akita H. et al. (2012) Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1. Nat Immunol 29 July 2012 (Epub ahead of print).
    • (2012) Nat Immunol
    • Chiba, S.1    Baghdadi, M.2    Akiba, H.3    Yoshiyama, H.4    Kinoshita, I.5    Dosaka-Akita, H.6
  • 14
    • 84857687171 scopus 로고    scopus 로고
    • TNF superfamily in inflammatory disease: translating basic insights
    • Croft M. Duan W. Choi H. Eun S. Madireddi S. Mehta A. (2012) TNF superfamily in inflammatory disease: translating basic insights. Trends Immunol 33: 144–152.
    • (2012) Trends Immunol , vol.33 , pp. 144-152
    • Croft, M.1    Duan, W.2    Choi, H.3    Eun, S.4    Madireddi, S.5    Mehta, A.6
  • 16
    • 77749279776 scopus 로고    scopus 로고
    • PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B 16 melanoma tumors
    • Curran M. Montalvo W. Yagita H. Allison J. (2010) PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B 16 melanoma tumors. Proc Natl Acad Sci 107: 4275–4280.
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 4275-4280
    • Curran, M.1    Montalvo, W.2    Yagita, H.3    Allison, J.4
  • 17
    • 84866784798 scopus 로고    scopus 로고
    • Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
    • de Nardo D. Brennan D. Rexhepaj E. Ruffell B. Shiao S. Madden S. et al. (2011) Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discovery 1: 54–67.
    • (2011) Cancer Discovery , vol.1 , pp. 54-67
    • de Nardo, D.1    Brennan, D.2    Rexhepaj, E.3    Ruffell, B.4    Shiao, S.5    Madden, S.6
  • 18
    • 73949092850 scopus 로고    scopus 로고
    • Tumor-Associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer
    • Denkert C. Loibl S. Noske A. Roller M. Müller B. Komor M. et al. (2010) Tumor-Associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer. J Clin Oncol 28: 105–113.
    • (2010) J Clin Oncol , vol.28 , pp. 105-113
    • Denkert, C.1    Loibl, S.2    Noske, A.3    Roller, M.4    Müller, B.5    Komor, M.6
  • 20
    • 34547661993 scopus 로고    scopus 로고
    • Triple-negative breast cancer: clinical features and patterns of recurrence
    • Dent R. Trudeau M. Pritchard K. Hanna W. Kahn H. Sawka C. et al. (2007) Triple-negative breast cancer: clinical features and patterns of recurrence. Clin Cancer Res 13: 4429–4434.
    • (2007) Clin Cancer Res , vol.13 , pp. 4429-4434
    • Dent, R.1    Trudeau, M.2    Pritchard, K.3    Hanna, W.4    Kahn, H.5    Sawka, C.6
  • 21
    • 51349088017 scopus 로고    scopus 로고
    • Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes
    • Desmedt C. Haibe-Kains B. Wirapati P. Buyse M. Larsimont D. Bontempi G. et al. (2008) Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes. Clin Cancer Res 14: 5158–5165.
    • (2008) Clin Cancer Res , vol.14 , pp. 5158-5165
    • Desmedt, C.1    Haibe-Kains, B.2    Wirapati, P.3    Buyse, M.4    Larsimont, D.5    Bontempi, G.6
  • 23
  • 25
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: impact on clinical outcome
    • Fridman W. Pagès F. Sautès-Fridman C. Galon J. (2012) The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer 12: 298–306.
    • (2012) Nat Rev Cancer , vol.12 , pp. 298-306
    • Fridman, W.1    Pagès, F.2    Sautès-Fridman, C.3    Galon, J.4
  • 26
    • 33745660509 scopus 로고    scopus 로고
    • Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast
    • Fulford L. Easton D. Reis-Filho J. Sofronis A. Gillett C. Lakhani S. et al. (2006) Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. Histopathology 49: 22–34.
    • (2006) Histopathology , vol.49 , pp. 22-34
    • Fulford, L.1    Easton, D.2    Reis-Filho, J.3    Sofronis, A.4    Gillett, C.5    Lakhani, S.6
  • 28
    • 84859613828 scopus 로고    scopus 로고
    • Clinical significance of circulating interleukin-23 as a prognostic factor in breast cancer patients
    • Gangemi S. Minciullo P. Adamo B. Franchina T. Ricciardi G. Ferraro M. et al. (2012) Clinical significance of circulating interleukin-23 as a prognostic factor in breast cancer patients. J Cell Biochem 113: 2122–2125.
    • (2012) J Cell Biochem , vol.113 , pp. 2122-2125
    • Gangemi, S.1    Minciullo, P.2    Adamo, B.3    Franchina, T.4    Ricciardi, G.5    Ferraro, M.6
  • 29
    • 61549122071 scopus 로고    scopus 로고
    • Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma
    • Gao Q. Wang X. Qiu S. Yamato I. Sho M. Nakajima Y. et al. (2009) Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma. Clin Cancer Res 15: 971–979.
    • (2009) Clin Cancer Res , vol.15 , pp. 971-979
    • Gao, Q.1    Wang, X.2    Qiu, S.3    Yamato, I.4    Sho, M.5    Nakajima, Y.6
  • 30
    • 70350569295 scopus 로고    scopus 로고
    • Activation of the NLRP 3 inflammasome in dendritic cells induces IL-1β-dependent adaptive immunity against tumors
    • Ghiringhelli F. Apetoh L. Tesniere A. Aymeric L. Ma Y. Ortiz C. et al. (2009) Activation of the NLRP 3 inflammasome in dendritic cells induces IL-1β-dependent adaptive immunity against tumors. Nat Med 15: 1170–1178.
    • (2009) Nat Med , vol.15 , pp. 1170-1178
    • Ghiringhelli, F.1    Apetoh, L.2    Tesniere, A.3    Aymeric, L.4    Ma, Y.5    Ortiz, C.6
  • 32
    • 82655189563 scopus 로고    scopus 로고
    • Lactoferrin–endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes
    • Ha N. Nair V. Reddy D. Mudvari P. Ohshiro K. Ghanta K. et al. (2011) Lactoferrin–endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes. Cancer Res 71: 7259–7269.
    • (2011) Cancer Res , vol.71 , pp. 7259-7269
    • Ha, N.1    Nair, V.2    Reddy, D.3    Mudvari, P.4    Ohshiro, K.5    Ghanta, K.6
  • 33
    • 77954526150 scopus 로고    scopus 로고
    • American Society of Clinical Oncology / College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer
    • Hammond M. Hayes D. Dowsett M. Allred D. Hagerty K. Badve S. et al. (2010) American Society of Clinical Oncology / College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. J Clin Oncol 28: 2784–2795.
    • (2010) J Clin Oncol , vol.28 , pp. 2784-2795
    • Hammond, M.1    Hayes, D.2    Dowsett, M.3    Allred, D.4    Hagerty, K.5    Badve, S.6
  • 34
    • 13444270323 scopus 로고    scopus 로고
    • Blockade of B7–H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
    • Hirano F. Kaneko K. Tamura H. Dong H. Wang S. Ichikawa M. et al. (2005) Blockade of B7–H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity. Cancer Res 65: 1089–1096.
    • (2005) Cancer Res , vol.65 , pp. 1089-1096
    • Hirano, F.1    Kaneko, K.2    Tamura, H.3    Dong, H.4    Wang, S.5    Ichikawa, M.6
  • 35
    • 84863936531 scopus 로고    scopus 로고
    • Gene modules and response to neoadjuvant chemotherapy in breast cancer subtypes: a pooled analysis
    • Ignatiadis M. Singhal S. Desmedt C. Haibe-Kains B. Criscitiello C. Andre F. et al. (2012) Gene modules and response to neoadjuvant chemotherapy in breast cancer subtypes: a pooled analysis. J Clin Oncol 30: 1996–2004.
    • (2012) J Clin Oncol , vol.30 , pp. 1996-2004
    • Ignatiadis, M.1    Singhal, S.2    Desmedt, C.3    Haibe-Kains, B.4    Criscitiello, C.5    Andre, F.6
  • 36
    • 77956535599 scopus 로고    scopus 로고
    • Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor
    • Jena B. Dotti G. Cooper L. (2010) Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor. Blood 116: 1035–1044.
    • (2010) Blood , vol.116 , pp. 1035-1044
    • Jena, B.1    Dotti, G.2    Cooper, L.3
  • 37
    • 0037168608 scopus 로고    scopus 로고
    • A unique molecular chaperone Cosmc required for activity of the mammalian core 1 B3-galactosyltransferase
    • Ju T. Cummings R. (2002) A unique molecular chaperone Cosmc required for activity of the mammalian core 1 B3-galactosyltransferase. Proc Natl Acad Sci 99: 16613–16618.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 16613-16618
    • Ju, T.1    Cummings, R.2
  • 38
    • 79953653271 scopus 로고    scopus 로고
    • Treatment and side effect management of CTLA-4 antibody therapy in metastatic melanoma
    • Kähler K. Hauschild A. (2011) Treatment and side effect management of CTLA-4 antibody therapy in metastatic melanoma. J Dtsch Dermatol Ges 9: 277–286.
    • (2011) J Dtsch Dermatol Ges , vol.9 , pp. 277-286
    • Kähler, K.1    Hauschild, A.2
  • 39
    • 83255185240 scopus 로고    scopus 로고
    • Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation
    • Karn T. Pusztai L. Ruckhäberle E. Liedtke C. Müller V. Schmidt M. et al. (2012) Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation. Eur J Cancer 48: 12–23.
    • (2012) Eur J Cancer , vol.48 , pp. 12-23
    • Karn, T.1    Pusztai, L.2    Ruckhäberle, E.3    Liedtke, C.4    Müller, V.5    Schmidt, M.6
  • 40
    • 84856000561 scopus 로고    scopus 로고
    • Immune recognition of tumor-associated mucin MUC 1 is achieved by a fully synthetic aberrantly glycosylated MUC 1 tripartite vaccine
    • Lakshminarayanan V. Thompson P. Wolfert M. Buskas T. Bradley J. Pathangey L. et al. (2012) Immune recognition of tumor-associated mucin MUC 1 is achieved by a fully synthetic aberrantly glycosylated MUC 1 tripartite vaccine. Proc Natl Acad Sci 109: 261–266.
    • (2012) Proc Natl Acad Sci , vol.109 , pp. 261-266
    • Lakshminarayanan, V.1    Thompson, P.2    Wolfert, M.3    Buskas, T.4    Bradley, J.5    Pathangey, L.6
  • 42
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • Lehmann B. Bauer J. Chen X. Sanders M. Chakravarthy A. Shyr Y. et al. (2011) Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 121: 2750–2767.
    • (2011) J Clin Invest , vol.121 , pp. 2750-2767
    • Lehmann, B.1    Bauer, J.2    Chen, X.3    Sanders, M.4    Chakravarthy, A.5    Shyr, Y.6
  • 43
    • 41649102048 scopus 로고    scopus 로고
    • Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
    • Liedtke C. Mazouni C. Hess K. André F. Tordai A. Mejia J. et al. (2008) Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer. J Clin Oncol 26: 1275–1281.
    • (2008) J Clin Oncol , vol.26 , pp. 1275-1281
    • Liedtke, C.1    Mazouni, C.2    Hess, K.3    André, F.4    Tordai, A.5    Mejia, J.6
  • 44
    • 84862784272 scopus 로고    scopus 로고
    • CD8+ lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer
    • Liu S. Lachapelle J. Leung S. Gao D. Foulkes W. Nielsen T. (2012) CD8+ lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer. Breast Cancer Res 14: R48.
    • (2012) Breast Cancer Res , vol.14 , pp. R48
    • Liu, S.1    Lachapelle, J.2    Leung, S.3    Gao, D.4    Foulkes, W.5    Nielsen, T.6
  • 45
    • 33846197980 scopus 로고    scopus 로고
    • Identification of a basal-like subtype of breast ductal carcinoma in situ
    • Livasy C. Perou C. Karaca G. Cowan D. Maia D. Jackson S. et al. (2007) Identification of a basal-like subtype of breast ductal carcinoma in situ. Hum Pathol 38: 197–204.
    • (2007) Hum Pathol , vol.38 , pp. 197-204
    • Livasy, C.1    Perou, C.2    Karaca, G.3    Cowan, D.4    Maia, D.5    Jackson, S.6
  • 46
    • 58149236915 scopus 로고    scopus 로고
    • Race and triple negative threats to breast cancer survival: a population-based study in Atlanta, GA
    • Lund M. Trivers K. Porter P. Coates R. Leyland-Jones B. Brawley O. et al. (2009) Race and triple negative threats to breast cancer survival: a population-based study in Atlanta, GA. Breast Cancer Res Treat 113: 357–370.
    • (2009) Breast Cancer Res Treat , vol.113 , pp. 357-370
    • Lund, M.1    Trivers, K.2    Porter, P.3    Coates, R.4    Leyland-Jones, B.5    Brawley, O.6
  • 47
    • 79956329617 scopus 로고    scopus 로고
    • Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer
    • Mahmoud S. Paish E. Powe D. Macmillan R. Grainge M. Lee A. et al. (2011) Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer. J Clin Oncol 29: 1949–1955.
    • (2011) J Clin Oncol , vol.29 , pp. 1949-1955
    • Mahmoud, S.1    Paish, E.2    Powe, D.3    Macmillan, R.4    Grainge, M.5    Lee, A.6
  • 48
    • 79960426821 scopus 로고    scopus 로고
    • Pivotal role of innate and adaptive immunity in anthracycline chemotherapy of established tumors
    • Mattarollo S. Loi S. Duret H. Ma Y. Zitvogel L. Smyth M. (2011) Pivotal role of innate and adaptive immunity in anthracycline chemotherapy of established tumors. Cancer Res 71: 4809–4820.
    • (2011) Cancer Res , vol.71 , pp. 4809-4820
    • Mattarollo, S.1    Loi, S.2    Duret, H.3    Ma, Y.4    Zitvogel, L.5    Smyth, M.6
  • 49
    • 84879319750 scopus 로고    scopus 로고
    • 11 Lymph node ratio is an independent risk classifier in node positive breast cancer patients: results of the phase III BIG 02–98 trial
    • Metzger O. de Azambuja E. Quinaux E. Francis P. Buyse M. Crown J. et al. (2010) 11 Lymph node ratio is an independent risk classifier in node positive breast cancer patients: results of the phase III BIG 02–98 trial. Eur J Cancer Suppl 8: 61.
    • (2010) Eur J Cancer Suppl , vol.8 , pp. 61
    • Metzger, O.1    de Azambuja, E.2    Quinaux, E.3    Francis, P.4    Buyse, M.5    Crown, J.6
  • 50
    • 79952093380 scopus 로고    scopus 로고
    • Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction
    • Mlecnik B. Tosolini M. Kirilovsky A. Berger A. Bindea G. Meatchi T. et al. (2011) Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction. J Clin Oncol 29: 610–618.
    • (2011) J Clin Oncol , vol.29 , pp. 610-618
    • Mlecnik, B.1    Tosolini, M.2    Kirilovsky, A.3    Berger, A.4    Bindea, G.5    Meatchi, T.6
  • 51
    • 77956218241 scopus 로고    scopus 로고
    • BRCA 1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
    • Molyneux G. Geyer F. Magnay F. McCarthy A. Kendrick H. Natrajan R. et al. (2010) BRCA 1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell 7: 403–417.
    • (2010) Cell Stem Cell , vol.7 , pp. 403-417
    • Molyneux, G.1    Geyer, F.2    Magnay, F.3    McCarthy, A.4    Kendrick, H.5    Natrajan, R.6
  • 52
    • 77950475517 scopus 로고    scopus 로고
    • Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
    • Morgan R. Yang J. Kitano M. Dudley M. Laurencot C. Rosenberg S. (2010) Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther 18: 843–851.
    • (2010) Mol Ther , vol.18 , pp. 843-851
    • Morgan, R.1    Yang, J.2    Kitano, M.3    Dudley, M.4    Laurencot, C.5    Rosenberg, S.6
  • 53
    • 77950403194 scopus 로고    scopus 로고
    • CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on Both hematopoietic and nonhematopoietic cells
    • Narazaki H. Zhu Y. Luo L. Zhu G. Chen L. (2010) CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on Both hematopoietic and nonhematopoietic cells. Blood 115: 1941–1948.
    • (2010) Blood , vol.115 , pp. 1941-1948
    • Narazaki, H.1    Zhu, Y.2    Luo, L.3    Zhu, G.4    Chen, L.5
  • 54
    • 79956103042 scopus 로고    scopus 로고
    • Anti-TIM3 antibody promotes T Ccell IFN-γ–mediated antitumor immunity and suppresses established tumors
    • Ngiow S. von Scheidt B. Akiba H. Yagita H. Teng M. Smyth M. (2011) Anti-TIM3 antibody promotes T Ccell IFN-γ–mediated antitumor immunity and suppresses established tumors. Cancer Res 71: 3540–3551.
    • (2011) Cancer Res , vol.71 , pp. 3540-3551
    • Ngiow, S.1    von Scheidt, B.2    Akiba, H.3    Yagita, H.4    Teng, M.5    Smyth, M.6
  • 55
    • 4143150688 scopus 로고    scopus 로고
    • Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma
    • Nielsen T. Hsu F. Jensen K. Cheang M. Karaca G. Hu Z. et al. (2004) Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res 10: 5367–5374.
    • (2004) Clin Cancer Res , vol.10 , pp. 5367-5374
    • Nielsen, T.1    Hsu, F.2    Jensen, K.3    Cheang, M.4    Karaca, G.5    Hu, Z.6
  • 56
    • 79551524395 scopus 로고    scopus 로고
    • Agonist ati-CD137 m Ab act on tumor endothelial cells to enhance recruitment of activated T lymphocytes
    • Palazón A. Teijeira A. Martínez-Forero I. Hervás-Stubbs S. Roncal C. Peñuelas I. et al. (2011) Agonist ati-CD137 m Ab act on tumor endothelial cells to enhance recruitment of activated T lymphocytes. Cancer Res 71: 801–811.
    • (2011) Cancer Res , vol.71 , pp. 801-811
    • Palazón, A.1    Teijeira, A.2    Martínez-Forero, I.3    Hervás-Stubbs, S.4    Roncal, C.5    Peñuelas, I.6
  • 58
    • 42249097689 scopus 로고    scopus 로고
    • OX 40 Triggering blocks suppression by regulatory T cells and facilitates tumor rejection
    • Piconese S. Valzasina B. Colombo M. (2008) OX 40 Triggering blocks suppression by regulatory T cells and facilitates tumor rejection. J Exp Med 205: 825–839.
    • (2008) J Exp Med , vol.205 , pp. 825-839
    • Piconese, S.1    Valzasina, B.2    Colombo, M.3
  • 59
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor–modified T cells in chronic lymphoid leukemia
    • Porter D. Levine B. Kalos M. Bagg A. June C. (2011) Chimeric antigen receptor–modified T cells in chronic lymphoid leukemia. N Engl J Med 365: 725–733.
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.1    Levine, B.2    Kalos, M.3    Bagg, A.4    June, C.5
  • 60
    • 78049308800 scopus 로고    scopus 로고
    • Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
    • Prat A. Parker J. Karginova O. Fan C. Livasy C. Herschkowitz J. et al. (2010) Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res 12: 1–18.
    • (2010) Breast Cancer Res , vol.12 , pp. 1-18
    • Prat, A.1    Parker, J.2    Karginova, O.3    Fan, C.4    Livasy, C.5    Herschkowitz, J.6
  • 61
    • 33745851479 scopus 로고    scopus 로고
    • CTLA 4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells
    • Quezada S. Peggs K. Curran M. Allison J. (2006) CTLA 4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells. J Clin Invest 116: 1935–1945.
    • (2006) J Clin Invest , vol.116 , pp. 1935-1945
    • Quezada, S.1    Peggs, K.2    Curran, M.3    Allison, J.4
  • 62
    • 57749092800 scopus 로고    scopus 로고
    • Triple-negative/basal-like breast cancer
    • Rakha E. Ellis I. (2009) Triple-negative/basal-like breast cancer. Pathology 41: 40–47.
    • (2009) Pathology , vol.41 , pp. 40-47
    • Rakha, E.1    Ellis, I.2
  • 63
    • 84868669212 scopus 로고    scopus 로고
    • Bat 3 promotes T cell responses and autoimmunity by repressing Tim-3-mediated cell death and exhaustion
    • Rangachari M. Zhu C. Sakuishi K. Xiao S. Karman J. Chen A. et al. (2012) Bat 3 promotes T cell responses and autoimmunity by repressing Tim-3-mediated cell death and exhaustion. Nat Med 18: 1394–1400.
    • (2012) Nat Med , vol.18 , pp. 1394-1400
    • Rangachari, M.1    Zhu, C.2    Sakuishi, K.3    Xiao, S.4    Karman, J.5    Chen, A.6
  • 65
    • 79960299888 scopus 로고    scopus 로고
    • Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
    • Rosenberg S. Yang J. Sherry R. Kammula U. Hughes M. Phan G. et al. (2011) Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy. Clin Cancer Res 17: 4550–4557.
    • (2011) Clin Cancer Res , vol.17 , pp. 4550-4557
    • Rosenberg, S.1    Yang, J.2    Sherry, R.3    Kammula, U.4    Hughes, M.5    Phan, G.6
  • 66
    • 77957744369 scopus 로고    scopus 로고
    • Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
    • Sakuishi K. Apetoh L. Sullivan J. Blazar B. Kuchroo V. Anderson A. (2010) Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J Exp Med 207: 2187–2194.
    • (2010) J Exp Med , vol.207 , pp. 2187-2194
    • Sakuishi, K.1    Apetoh, L.2    Sullivan, J.3    Blazar, B.4    Kuchroo, V.5    Anderson, A.6
  • 67
    • 44849101184 scopus 로고    scopus 로고
    • The humoral immune system has a key prognostic impact in node-negative breast cancer
    • Schmidt M. Böhm D. von Törne C. Steiner E. Puhl A. Pilch H. et al. (2008) The humoral immune system has a key prognostic impact in node-negative breast cancer. Cancer Res 68: 5405–5413.
    • (2008) Cancer Res , vol.68 , pp. 5405-5413
    • Schmidt, M.1    Böhm, D.2    von Törne, C.3    Steiner, E.4    Puhl, A.5    Pilch, H.6
  • 68
    • 84860532352 scopus 로고    scopus 로고
    • A comprehensive analysis of human gene expression profiles identifies stromal immunoglobulin kappa c as a compatible prognostic marker in human solid tumors
    • Schmidt M. Hellwig B. Hammad S. Othman A. Lohr M. Chen Z. et al. (2012) A comprehensive analysis of human gene expression profiles identifies stromal immunoglobulin kappa c as a compatible prognostic marker in human solid tumors. Clin Cancer Res 18: 2695–2703.
    • (2012) Clin Cancer Res , vol.18 , pp. 2695-2703
    • Schmidt, M.1    Hellwig, B.2    Hammad, S.3    Othman, A.4    Lohr, M.5    Chen, Z.6
  • 69
    • 84862526929 scopus 로고    scopus 로고
    • The clonal and mutational evolution spectrum of primary triple-negative breast cancers
    • Shah S. Roth A. Goya R. Oloumi A. Ha G. Zhao Y. et al. (2012) The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature 486: 395–399.
    • (2012) Nature , vol.486 , pp. 395-399
    • Shah, S.1    Roth, A.2    Goya, R.3    Oloumi, A.4    Ha, G.5    Zhao, Y.6
  • 72
    • 79954576658 scopus 로고    scopus 로고
    • CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis
    • Stagg J. Divisekera U. Duret H. Sparwasser T. Teng M. Darcy P. et al. (2011) CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis. Cancer Res 71: 2892–2900.
    • (2011) Cancer Res , vol.71 , pp. 2892-2900
    • Stagg, J.1    Divisekera, U.2    Duret, H.3    Sparwasser, T.4    Teng, M.5    Darcy, P.6
  • 74
    • 35748972927 scopus 로고    scopus 로고
    • From cancer immunosurveillance to cancer immunotherapy
    • Stagg J. Johnstone R. Smyth M. (2007) From cancer immunosurveillance to cancer immunotherapy. Immunol Rev 220: 82–101.
    • (2007) Immunol Rev , vol.220 , pp. 82-101
    • Stagg, J.1    Johnstone, R.2    Smyth, M.3
  • 75
    • 77957564570 scopus 로고    scopus 로고
    • Extracellular adenosine triphosphate and adenosine in cancer
    • Stagg J. Smyth M. (2010) Extracellular adenosine triphosphate and adenosine in cancer. Oncogene 29: 5346–5358.
    • (2010) Oncogene , vol.29 , pp. 5346-5358
    • Stagg, J.1    Smyth, M.2
  • 76
    • 84861576201 scopus 로고    scopus 로고
    • The landscape of cancer genes and mutational processes in breast cancer
    • Stephens P. Tarpey P. Davies H. Loo P. Greenman C. Wedge D. et al. (2012) The landscape of cancer genes and mutational processes in breast cancer. Nature 486: 400–404.
    • (2012) Nature , vol.486 , pp. 400-404
    • Stephens, P.1    Tarpey, P.2    Davies, H.3    Loo, P.4    Greenman, C.5    Wedge, D.6
  • 78
    • 79952746350 scopus 로고    scopus 로고
    • Anti-IL-23 monoclonal antibody synergizes in combination with targeted therapies or IL-2 to suppress tumor growth and metastases
    • Teng M. von Scheidt B. Duret H. Towne J. Smyth M. (2011) Anti-IL-23 monoclonal antibody synergizes in combination with targeted therapies or IL-2 to suppress tumor growth and metastases. Cancer Res 71: 2077–2086.
    • (2011) Cancer Res , vol.71 , pp. 2077-2086
    • Teng, M.1    von Scheidt, B.2    Duret, H.3    Towne, J.4    Smyth, M.5
  • 79
    • 34648829133 scopus 로고    scopus 로고
    • An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer
    • Teschendorff A. Miremadi A. Pinder S. Ellis I. Caldas C. (2007) An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer. Genome Biol 8: R157.
    • (2007) Genome Biol , vol.8 , pp. R157
    • Teschendorff, A.1    Miremadi, A.2    Pinder, S.3    Ellis, I.4    Caldas, C.5
  • 80
    • 34247364939 scopus 로고    scopus 로고
    • NY-ESO-1 protein expression in primary breast carcinoma and metastases–correlation with CD8+ T-cell and CD79a+ plasmacytic/B-cell Infiltration
    • Theurillat J. Ingold F. Frei C. Zippelius A. Varga Z. Seifert B. et al. (2007) NY-ESO-1 protein expression in primary breast carcinoma and metastases–correlation with CD8+ T-cell and CD79a+ plasmacytic/B-cell Infiltration. Int J Cancer 120: 2411–2417.
    • (2007) Int J Cancer , vol.120 , pp. 2411-2417
    • Theurillat, J.1    Ingold, F.2    Frei, C.3    Zippelius, A.4    Varga, Z.5    Seifert, B.6
  • 81
  • 82
    • 77249089345 scopus 로고    scopus 로고
    • MAGRIT: the largest-ever phase III lung cancer trial aims to establish a novel tumor-specific approach to therapy
    • Tyagi P. Mirakhur B. (2009) MAGRIT: the largest-ever phase III lung cancer trial aims to establish a novel tumor-specific approach to therapy. Clin Lung Cancer 10: 371–374.
    • (2009) Clin Lung Cancer , vol.10 , pp. 371-374
    • Tyagi, P.1    Mirakhur, B.2
  • 83
    • 0034662639 scopus 로고    scopus 로고
    • Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients
    • Valmori D. Dutoit V. Liénard D. Rimoldi D. Pittet M. Champagne P. et al. (2000) Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients. Cancer Res 60: 4499–4506.
    • (2000) Cancer Res , vol.60 , pp. 4499-4506
    • Valmori, D.1    Dutoit, V.2    Liénard, D.3    Rimoldi, D.4    Pittet, M.5    Champagne, P.6
  • 84
    • 17344392248 scopus 로고    scopus 로고
    • Survival in early breast cancer patients is favorably influenced by a natural humoral immune response to polymorphic epithelial mucin
    • von Mensdorff-Pouilly S. Verstraeten A. Kenemans P. Snijdewint F. Kok A. Kamp G. et al. (2000) Survival in early breast cancer patients is favorably influenced by a natural humoral immune response to polymorphic epithelial mucin. J Clin Oncol 18: 574–575.
    • (2000) J Clin Oncol , vol.18 , pp. 574-575
    • von Mensdorff-Pouilly, S.1    Verstraeten, A.2    Kenemans, P.3    Snijdewint, F.4    Kok, A.5    Kamp, G.6
  • 85
    • 79957921286 scopus 로고    scopus 로고
    • CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice
    • Wang L. Fan J. Thompson L. Zhang Y. Shin T. Curiel T. et al. (2011) CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice. J Clin Invest 121: 2371–2382.
    • (2011) J Clin Invest , vol.121 , pp. 2371-2382
    • Wang, L.1    Fan, J.2    Thompson, L.3    Zhang, Y.4    Shin, T.5    Curiel, T.6
  • 86
    • 82955217260 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
    • West N. Milne K. Truong P. Macpherson N. Nelson B. Watson P. (2011) Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer. Breast Cancer Res 13: R126.
    • (2011) Breast Cancer Res , vol.13 , pp. R126
    • West, N.1    Milne, K.2    Truong, P.3    Macpherson, N.4    Nelson, B.5    Watson, P.6
  • 87
    • 33847147313 scopus 로고    scopus 로고
    • American Society of Clinical Oncology / College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
    • Wolff A. Hammond M. Schwartz J. Hagerty K. Allred D. Cote R. et al. (2006) American Society of Clinical Oncology / College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol 25: 118–145.
    • (2006) J Clin Oncol , vol.25 , pp. 118-145
    • Wolff, A.1    Hammond, M.2    Schwartz, J.3    Hagerty, K.4    Allred, D.5    Cote, R.6
  • 88
    • 84863115998 scopus 로고    scopus 로고
    • Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape
    • Woo S. Turnis M. Goldberg M. Bankoti J. Selby M. Nirschl C. et al. (2012) Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Res 72: 917–927.
    • (2012) Cancer Res , vol.72 , pp. 917-927
    • Woo, S.1    Turnis, M.2    Goldberg, M.3    Bankoti, J.4    Selby, M.5    Nirschl, C.6
  • 90
    • 37349014037 scopus 로고    scopus 로고
    • Chemopreventive agents induce programmed death-1-ligand 1 (PD-L1) surface expression in breast cancer cells and promote PD-L1-mediated T cell apoptosis
    • Zhang P. Su D. Liang M. Fu J. (2008) Chemopreventive agents induce programmed death-1-ligand 1 (PD-L1) surface expression in breast cancer cells and promote PD-L1-mediated T cell apoptosis. Mol Immunol 45: 1470–1476.
    • (2008) Mol Immunol , vol.45 , pp. 1470-1476
    • Zhang, P.1    Su, D.2    Liang, M.3    Fu, J.4


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