Complexes between linoleate and native or aggregated β-lactoglobulin: Interaction parameters and in vitro cytotoxic effect

Food Chemistry

Volumn 141, Issue 3, 2013, Pages 2305-2313

  Le Maux, Solène ^a,b   Bouhallab, Saïd ^a   Giblin, Linda ^b   Brodkorb, André ^b   Croguennec, Thomas ^a  

^a UMR1253   (France)

^b TEAGASC FOOD RESEARCH CENTRE   (Ireland)

Author keywords

Aggregation; Cytotoxicity; Interaction; Linoleate; Lactoglobulin

Indexed keywords

AGGLOMERATION; BINDING SITES; BINS; FATTY ACIDS; FOOD PRODUCTS; NANOCAPSULES; NANOPARTICLES;

ASSOCIATION CONSTANT; CYTOTOXICITY ASSAYS; INDUSTRIAL PROCESSING; INTERACTION; INTERACTION PARAMETERS; ISOTHERMAL TITRATION CALORIMETRY; LACTOGLOBULIN; LINOLEATE;

CYTOTOXICITY;

BETA LACTOGLOBULIN; LINOLEIC ACID; NANOPARTICLE;

ARTICLE; BINDING SITE; CELL STRAIN CACO 2; COMPLEX FORMATION; DRUG CYTOTOXICITY; FLUORESCENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOTHERMAL TITRATION CALORIMETRY; PARTICLE SIZE; PROTEIN AGGREGATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; STOICHIOMETRY;

BOVINAE;

EID: 84879244104     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2013.05.031     Document Type: Article

References (38)

1. Alghazeer, R., Gao, H. L., & Howell, N. K. (2008). Cytotoxicity of oxidised lipids in cultured colonal human intestinal cancer cells (caco-2 cells). Toxicology Letters, 180(3), 202-211.
2. Bouchemal, K. (2008). New challenges for pharmaceutical formulations and drug delivery systems characterization using isothermal titration calorimetry. Drug Discovery Today, 13(21-22), 960-972.
3. Braunitzer, G., Chen, R., Schrank, B., & Stangl, A. (1973). Die sequenzanalyse des blactoglobulins. Hoppe-Seyleŕs Zeitschrift für physiologische Chemie, 354(2), 867-878.
4. Coakley, M., Ross, R. P., Nordgren, M., Fitzgerald, G., Devery, R., & Stanton, C. (2003). Conjugated linoleic acid biosynthesis by human-derived Bifidobacterium species. Journal of Applied Microbiology, 94(1), 138-145. (Pubitemid 36051315)
5. Cogan, U., Kopelman, M., Mokady, S., & Shinitzky, M. (1976). Binding affinities of retinol and related compounds to retinol binding proteins. European Journal of Biochemistry, 65(1), 71-78.
6. Considine, T., Patel, H. A., Anema, S. G., Singh, H., & Creamer, L. K. (2007). Interactions of milk proteins during heat and high hydrostatic pressure treatments -A review. Innovative Food Science & Emerging Technologies, 8(1), 1-23. (Pubitemid 46217251)
7. Creamer, L. K., Parry, D. A. D., & Malcolm, G. N. (1983). Secondary structure of bovine beta-lactoglobulin B. Archives of Biochemistry and Biophysics, 227(1), 98-105.
8. de Wit, J. N. (2009). Thermal behaviour of bovine beta-lactoglobulin at temperatures up to 150 °C. A review. Trends in Food Science and Technology, 20(1), 27-34.
9. Frémont, L., Belguendouz, L., & Delpal, S. (1999). Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids. Life Sciences, 64(26), 2511-2521. (Pubitemid 29268427)
10. Gulzar, M., Croguennec, T., Jardin, J., Piot, M., & Bouhallab, S. (2009). Copper modulates the heat-induced sulfhydryl/disulfide interchange reactions of betalactoglobulin. Food Chemistry, 116(4), 884-891.
11. Jensen, R. G. (2002). The composition of bovine milk lipids: January 1995 to December 2000. Journal of Dairy Science, 85(2), 295-350. (Pubitemid 38562804)
12. Kleinveld, H. A., Hak-Lemmers, H., Stalenhoef, A., & Demacker, P. (1992). Improved measurement of low-density-lipoprotein susceptibility to copper-induced oxidation: Application of a short procedure for isolating low-density lipoprotein. Clinical Chemistry, 38(10), 2066-2072.
13. Kontopidis, G., Holt, C., & Sawyer, L. (2004). Invited review: Beta-lactoglobulin: Binding properties, structure, and function. Journal of Dairy Science, 87(4), 785-796. (Pubitemid 44151704)
14. Le Maux, S., Giblin, L., Croguennec, T., Bouhallab, S., & Brodkorb, A. (2012). Betalactoglobulin as a molecular carrier of linoleate: Characterisation and effects on intestinal epithelial cells in vitro. Journal of Agricultural and Food Chemistry, 60(37), 9476-9483.
15. Lišková, K., Auty, M. A. E., Chaurin, V., Min, S., Mok, K. H., O'Brien, N., et al. (2011). Cytotoxic complexes of sodium oleate with beta-lactoglobulin. European Journal of Lipid Science and Technology, 1207-1218.
16. Loch, J., Polit, A., Bonarek, P., Ries, D., Kurpiewska, K., Dziedzicka Wasylewska, M., & Lewi ski, K. (2012b). Bovine beta-lactoglobulin complex with linoleic acid. In URL (http://www.rcsb.org/pdb/explore/explore.do? structureId=4DQ4) DOI:10.2210/pdb4dq4/pdb, vol. (most recent, accessed 5.06.12)).
17. Loch, J., Polit, A., Bonarek, P., Olszewska, D., Kurpiewska, K., Dziedzicka-Wasylewska, M., et al. (2012a). Structural and thermodynamic studies of binding saturated fatty acids to bovine beta-lactoglobulin. International Journal of Biological Macromolecules, 50(4), 1095-1102.
18. Lu, X., He, G., Yu, H., Ma, Q., Shen, S., & Das, U. N. (2010). Colorectal cancer cell growth inhibition by linoleic acid is related to fatty acid composition changes. Journal of Zhejiang University Science B, 11(12), 923-930.
19. Mantzioris, E., James, M. J., Gibson, R. A., & Cleland, L. G. (1995). Differences exist in the relationships between dietary linoleic and alpha-linoleic acids and their respective long-chain metabolites. American Journal of Clinical Nutrition, 61(2), 320-324.
20. Mu, H. (2008). Bioavailability of omega-3 long-chain polyunsaturated fatty acids from foods. Agro Food Industry Hi-Tech: Focus on Omega-3, 19(4), 24-26.
21. O'Neill, T., & Kinsella, J. (1988). Effect of heat treatment and modification on conformation and flavor binding by beta-lactoglobulin. Journal of Food Science, 53(3), 906-909.
22. Palmquist, D. L., & Jenkins, T. C. (2003). Challenges with fats and fatty acid methods. Journal of Animal Science, 81(12), 3250-3254. (Pubitemid 38571606)
23. Perez, M. D., Sanchez, L., Aranda, P., Ena, J., Oria, R., & Calvo, M. (1992). Effect of betalactoglobulin on the activity of pregastric lipase. A possible role for this protein in ruminant milk. Biochimica et Biophysica Acta (BBA), Lipids and Lipid Metabolism, 1123(2), 151-155.
24. Ragona, L., Zetta, L., Fogolari, F., Molinari, H., Pérez, D. M., Puyol, P., et al. (2000). Bovine beta-lactoglobulin: Interaction studies with palmitic acid. Protein Science, 9(7), 1347-1356. (Pubitemid 30602288)
25. Renard, D., Lefebvre, J., Griffin, M. C. A., & Griffin, W. G. (1998). Effects of pH and salt environment on the association of beta-lactoglobulin revealed by intrinsic fluorescence studies. International Journal of Biological Macromolecules, 22(1), 41-49. (Pubitemid 28073619)
26. Ron, N., Zimet, P., Bargarum, J., & Livney, Y. (2010). Beta-lactoglobulin-polysaccharide complexes as nanovehicles for hydrophobic nutraceuticals in non-fat foods and clear beverages. International Dairy Journal, 20(10), 686-693.
27. Russo, G. L. (2009). Dietary n 6 and n 3 polyunsaturated fatty acids: From biochemistry to clinical implications in cardiovascular prevention. Biochemical Pharmacology, 77(6), 937-946.
28. Sawyer, L., & Kontopidis, G. (2000). The core lipocalin, bovine beta-lactoglobulin. Biochimica et Biophysica Acta (BBA), Protein Structure and Molecular Enzymology, 1482(1-2), 136-148.
29. Schmitt, C., Bovay, C., Vuilliomenet, A. M., Rouvet, M., Bovetto, L., Barbar, R., et al. (2009). Multiscale characterization of individualized beta-lactoglobulin microgels formed upon heat treatment under narrow pH range conditions. Langmuir, 25(14), 7899-7909.
30. Shpigelman, A., Israeli, G., & Livney, Y. D. (2010). Thermally-induced proteinpolyphenol co-Assemblies: Beta lactoglobulin-based nanocomplexes as protective nanovehicles for EGCG. Food Hydrocolloids, 24(8), 735-743.
31. Singh, H., Ye, A., & Horne, D. (2009). Structuring food emulsions in the gastrointestinal tract to modify lipid digestion. Progress in Lipid Research, 48(2), 92-100.
32. Spector, A. A., & Fletcher, J. E. (1970). Binding of long chain fatty acids to betalactoglobulin. Lipids, 5(4), 403-411.
33. Wang, Q. W. Q., Allen, J. C., & Swaisgood, H. E. (1998). Protein concentration dependence of palmitate binding to beta-lactoglobulin. Journal of Dairy Science, 81(1), 76-81. (Pubitemid 128458519)
34. Wu, S. Y., Pérez, M. D., Puyol, P., & Sawyer, L. (1999). Beta-lactoglobulin binds palmitate within its central cavity. Journal of Biological Chemistry, 274(1), 170-174. (Pubitemid 29035045)
35. Yang, M. C., Chen, N. C., Chen, C. J., Wu, C. Y., & Mao, S. J. T. (2009). Evidence for betalactoglobulin involvement in vitamin D transport in vivo-Role of the c-Turn (Leu-Pro-Met) of beta-lactoglobulin in vitamin D binding. FEBS Journal, 276(8), 2251-2265.
36. Yang, M. C., Guan, H. H., Liu, M. Y., Lin, Y. H., Yang, J. M., Chen, W. L., et al. (2008). Crystal structure of a secondary vitamin D3 binding site of milk betalactoglobulin. Proteins: Structure, Function, and Bioinformatics, 71(3), 1197-1210.
37. Zhao, G., Etherton, T. D., Martin, K. R., Vanden Heuvel, J. P., Gillies, P. J., & West, S. G. (2005). Anti-inflammatory effects of polyunsaturated fatty acids in THP-1 cells. Biochemical and Biophysical Research Communications, 336(3), 909-917. (Pubitemid 41338355)
38. Zock, P. L., & Katan, M. B. (1998). Linoleic acid intake and cancer risk: A review and meta-Analysis. American Journal of Clinical Nutrition, 68(1), 142-153. (Pubitemid 28307666)