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Volumn 91, Issue 2, 2012, Pages 303-309

Ketamine as a novel antidepressant: From synapse to behavior

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A;

EID: 84855940822     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2011.244     Document Type: Article
Times cited : (157)

References (41)
  • 2
    • 0009952205 scopus 로고    scopus 로고
    • American Psychiatric Association 4th edn., text revision American Psychiatric Association, Washington, DC
    • American Psychiatric Association. Task Force on DSM-IV. Diagnostic and Statistical Manual of Mental Disorders. 4th edn., text revision (American Psychiatric Association, Washington, DC, 2000).
    • (2000) Task Force on DSM-IV. Diagnostic and Statistical Manual of Mental Disorders
  • 4
    • 79960533628 scopus 로고    scopus 로고
    • Combining medications to enhance depression outcomes (CO-MED): Acute and long-term outcomes of a single-blind randomized study
    • Rush, A.J. et al. Combining medications to enhance depression outcomes (CO-MED): acute and long-term outcomes of a single-blind randomized study. Am. J. Psychiatry 168, 689-701 (2011).
    • (2011) Am. J. Psychiatry , vol.168 , pp. 689-701
    • Rush, A.J.1
  • 5
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan, V. & Nestler, E.J. The molecular neurobiology of depression. Nature 455, 894-902 (2008).
    • (2008) Nature , vol.455 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 9
    • 77949625234 scopus 로고    scopus 로고
    • Riluzole for relapse prevention following intravenous ketamine in treatment-resistant depression: A pilot randomized, placebocontrolled continuation trial
    • Mathew, S.J., Murrough, J.W., aan het Rot, M., Collins, K.A., Reich, D.L. & Charney, D.S. Riluzole for relapse prevention following intravenous ketamine in treatment-resistant depression: a pilot randomized, placebocontrolled continuation trial. Int. J. Neuropsychopharmacol. 13, 71-82 (2010).
    • (2010) Int. J. Neuropsychopharmacol. , vol.13 , pp. 71-82
    • Mathew, S.J.1    Murrough, J.W.2    Aanhet Rot, M.3    Collins, K.A.4    Reich, D.L.5    Charney, D.S.6
  • 10
    • 71649098114 scopus 로고    scopus 로고
    • Safety and efficacy of repeated-dose intravenous ketamine for treatment-resistant depression
    • aan het Rot, M. et al. Safety and efficacy of repeated-dose intravenous ketamine for treatment-resistant depression. Biol. Psychiatry 67, 139-145 (2010).
    • (2010) Biol. Psychiatry , vol.67 , pp. 139-145
    • Aanhet Rot, M.1
  • 11
    • 79953057998 scopus 로고    scopus 로고
    • A case of sustained remission following an acute course of ketamine in treatment-resistant depression
    • Murrough, J.W., Perez, A.M., Mathew, S.J. & Charney, D.S. A case of sustained remission following an acute course of ketamine in treatment-resistant depression. J. Clin. Psychiatry 72, 414-415 (2011).
    • (2011) J. Clin. Psychiatry , vol.72 , pp. 414-415
    • Murrough, J.W.1    Perez, A.M.2    Mathew, S.J.3    Charney, D.S.4
  • 12
    • 68049121850 scopus 로고    scopus 로고
    • Effects of intravenous ketamine on explicit and implicit measures of suicidality in treatmentresistant depression
    • Price, R.B., Nock, M.K., Charney, D.S. & Mathew, S.J. Effects of intravenous ketamine on explicit and implicit measures of suicidality in treatmentresistant depression. Biol. Psychiatry 66, 522-526 (2009).
    • (2009) Biol. Psychiatry , vol.66 , pp. 522-526
    • Price, R.B.1    Nock, M.K.2    Charney, D.S.3    Mathew, S.J.4
  • 13
    • 78650371169 scopus 로고    scopus 로고
    • Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatmentresistant major depressive disorder
    • DiazGranados, N. et al. Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatmentresistant major depressive disorder. J. Clin. Psychiatry 71, 1605-1611 (2010).
    • (2010) J. Clin. Psychiatry , vol.71 , pp. 1605-1611
    • Diazgranados, N.1
  • 14
    • 80053025475 scopus 로고    scopus 로고
    • Apreliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department
    • Larkin, G.L. & Beautrais, A.L. A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department. Int. J. Neuropsychopharmacol. 14, 1127-1131 (2011).
    • (2011) Int. J. Neuropsychopharmacol. , vol.14 , pp. 1127-1131
    • Larkin, G.L.1    Beautrais, A.L.2
  • 15
    • 0025157918 scopus 로고
    • Functional antagonists at the NMDA receptor complex exhibit antidepressant actions
    • DOI 10.1016/0014-2999(90)90204-J
    • Trullas, R. & Skolnick, P. Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. Eur. J. Pharmacol. 185, 1-10 (1990). (Pubitemid 20254891)
    • (1990) European Journal of Pharmacology , vol.185 , Issue.1 , pp. 1-10
    • Trullas, R.1    Skolnick, P.2
  • 16
    • 0030032399 scopus 로고    scopus 로고
    • Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: Implications for the pharmacotherapy of depression
    • Skolnick, P., Layer, R.T., Popik, P., Nowak, G., Paul, I.A. & Trullas, R. Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression. Pharmacopsychiatry 29, 23-26 (1996). (Pubitemid 26072654)
    • (1996) Pharmacopsychiatry , vol.29 , Issue.1 , pp. 23-26
    • Skolnick, P.1    Layer, R.T.2    Popik, P.3    Nowak, G.4    Paul, I.A.5    Trullas, R.6
  • 17
    • 77955909841 scopus 로고    scopus 로고
    • MTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists
    • Li, N. et al. mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science 329, 959-964 (2010).
    • (2010) Science , vol.329 , pp. 959-964
    • Li, N.1
  • 18
    • 79960057257 scopus 로고    scopus 로고
    • NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
    • Autry, A.E. et al. NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses. Nature 475, 91-95 (2011).
    • (2011) Nature , vol.475 , pp. 91-95
    • Autry, A.E.1
  • 19
    • 79953166373 scopus 로고    scopus 로고
    • Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure
    • Li, N. et al. Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. Biol. Psychiatry 69, 754-761 (2011).
    • (2011) Biol. Psychiatry , vol.69 , pp. 754-761
    • Li, N.1
  • 20
    • 74549122218 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist
    • Machado-Vieira, R. et al. Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist. J. Clin. Psychiatry 70, 1662-1666 (2009).
    • (2009) J. Clin. Psychiatry , vol.70 , pp. 1662-1666
    • MacHado-Vieira, R.1
  • 21
    • 63149184846 scopus 로고    scopus 로고
    • Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats
    • Garcia, L.S. et al. Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats. Prog. Neuropsychopharmacol. Biol. Psychiatry 33, 450-455 (2009).
    • (2009) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.33 , pp. 450-455
    • Garcia, L.S.1
  • 22
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman, R.S. & Monteggia, L.M. A neurotrophic model for stress-related mood disorders. Biol. Psychiatry 59, 1116-1127 (2006).
    • (2006) Biol. Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 23
    • 38349186799 scopus 로고    scopus 로고
    • Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors
    • DOI 10.1016/j.biopsych.2007.05.028, PII S0006322307005471
    • Maeng, S. et al. Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors. Biol. Psychiatry 63, 349-352 (2008). (Pubitemid 351146651)
    • (2008) Biological Psychiatry , vol.63 , Issue.4 , pp. 349-352
    • Maeng, S.1    Zarate Jr., C.A.2    Du, J.3    Schloesser, R.J.4    McCammon, J.5    Chen, G.6    Manji, H.K.7
  • 25
    • 82355182063 scopus 로고    scopus 로고
    • Cognitive dysfunction in depression: Neurocircuitry and new therapeutic strategies
    • e-pub ahead of print 16 June 2011
    • Murrough, J.W., Iacoviello, B., Neumeister, A., Charney, D.S. & Iosifescu, D.V. Cognitive dysfunction in depression: Neurocircuitry and new therapeutic strategies. Neurobiol. Learn. Mem. (2011); e-pub ahead of print 16 June 2011.
    • (2011) Neurobiol. Learn. Mem.
    • Murrough, J.W.1    Iacoviello, B.2    Neumeister, A.3    Charney, D.S.4    Iosifescu, D.V.5
  • 26
    • 0030900732 scopus 로고    scopus 로고
    • Activation of glutamatergic neurotransmission by ketamine: A novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
    • Moghaddam, B., Adams, B., Verma, A. & Daly, D. Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J. Neurosci. 17, 2921-2927 (1997). (Pubitemid 27155025)
    • (1997) Journal of Neuroscience , vol.17 , Issue.8 , pp. 2921-2927
    • Moghaddam, B.1    Adams, B.2    Verma, A.3    Daly, D.4
  • 27
    • 35548991088 scopus 로고    scopus 로고
    • NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons
    • DOI 10.1523/JNEUROSCI.2213-07.2007
    • Homayoun, H. & Moghaddam, B. NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons. J. Neurosci. 27, 11496-11500 (2007). (Pubitemid 350006886)
    • (2007) Journal of Neuroscience , vol.27 , Issue.43 , pp. 11496-11500
    • Homayoun, H.1    Moghaddam, B.2
  • 31
    • 27844508674 scopus 로고    scopus 로고
    • Effects of noncompetitive NMDA receptor blockade on anterior cingulate cerebral blood flow in volunteers with schizophrenia
    • DOI 10.1038/sj.npp.1300824, PII 1300824
    • Holcomb, H.H., Lahti, A.C., Medoff, D.R., Cullen, T. & Tamminga, C.A. Effects of noncompetitive NMDA receptor blockade on anterior cingulate cerebral blood flow in volunteers with schizophrenia. Neuropsychopharmacology 30, 2275-2282 (2005). (Pubitemid 41643980)
    • (2005) Neuropsychopharmacology , vol.30 , Issue.12 , pp. 2275-2282
    • Holcomb, H.H.1    Lahti, A.C.2    Medoff, D.R.3    Cullen, T.4    Tamminga, C.A.5
  • 32
    • 38949173198 scopus 로고    scopus 로고
    • Glutamate and the neural basis of the subjective effects of ketamine: A pharmaco-magnetic resonance imaging study
    • DOI 10.1001/archgenpsychiatry.2007.37
    • Deakin, J.F., Lees, J., McKie, S., Hallak, J.E., Williams, S.R. & Dursun, S.M. Glutamate and the neural basis of the subjective effects of ketamine: a pharmaco-magnetic resonance imaging study. Arch. Gen. Psychiatry 65, 154-164 (2008). (Pubitemid 351214314)
    • (2008) Archives of General Psychiatry , vol.65 , Issue.2 , pp. 154-164
    • Deakin, J.F.W.1    Lees, J.2    McKie, S.3    Hallak, J.E.C.4    Williams, S.R.5    Dursun, S.M.6
  • 34
    • 84855969139 scopus 로고    scopus 로고
    • Lack of effect of ketamine on cortical glutamate and glutamine in healthy volunteers: A proton magnetic resonance spectroscopy study
    • e-pub ahead of print 26 May 2011
    • Taylor, M.J., Tiangga, E.R., Ní Mhuircheartaigh, R. & Cowen, P. Lack of effect of ketamine on cortical glutamate and glutamine in healthy volunteers: a proton magnetic resonance spectroscopy study. J. Psychopharmacol. (2011); e-pub ahead of print 26 May 2011.
    • (2011) J. Psychopharmacol.
    • Taylor, M.J.1    Tiangga, E.R.2    Ní Mhuircheartaigh, R.3    Cowen, P.4
  • 35
    • 78649731928 scopus 로고    scopus 로고
    • Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex
    • Covington, H.E. 3rd et al. Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex. J. Neurosci. 30, 16082-16090 (2010).
    • (2010) J. Neurosci. , vol.30 , pp. 16082-16090
    • Covington Iii, H.E.1
  • 36
    • 58749093029 scopus 로고    scopus 로고
    • Increased anterior cingulate cortical activity in response to fearful faces: A neurophysiological biomarker that predicts rapid antidepressant response to ketamine
    • Salvadore, G. et al. Increased anterior cingulate cortical activity in response to fearful faces: a neurophysiological biomarker that predicts rapid antidepressant response to ketamine. Biol. Psychiatry 65, 289-295 (2009).
    • (2009) Biol. Psychiatry , vol.65 , pp. 289-295
    • Salvadore, G.1
  • 37
    • 77952428840 scopus 로고    scopus 로고
    • Anterior cingulate desynchronization and functional connectivity with the amygdala during a working memory task predict rapid antidepressant response to ketamine
    • Salvadore, G. et al. Anterior cingulate desynchronization and functional connectivity with the amygdala during a working memory task predict rapid antidepressant response to ketamine. Neuropsychopharmacology 35, 1415-1422 (2010).
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1415-1422
    • Salvadore, G.1
  • 38
    • 58049211903 scopus 로고    scopus 로고
    • Family history of alcohol dependence and initial antidepressant response to an N-methyl-D-aspartate antagonist
    • Phelps, L.E., Brutsche, N., Moral, J.R., Luckenbaugh, D.A., Manji, H.K. & Zarate, C.A. Jr. Family history of alcohol dependence and initial antidepressant response to an N-methyl-D-aspartate antagonist. Biol. Psychiatry 65, 181-184 (2009).
    • (2009) Biol. Psychiatry , vol.65 , pp. 181-184
    • Phelps, L.E.1    Brutsche, N.2    Moral, J.R.3    Luckenbaugh, D.A.4    Manji, H.K.5    Zarate Jr., C.A.6
  • 39
    • 38349097619 scopus 로고    scopus 로고
    • Acute administration of ketamine induces antidepressantlike effects in the forced swimming test and increases BDNF levels in the rat hippocampus
    • Garcia, L.S. et al. Acute administration of ketamine induces antidepressantlike effects in the forced swimming test and increases BDNF levels in the rat hippocampus. Prog. Neuropsychopharmacol. Biol. Psychiatry 32, 140-144 (2008).
    • (2008) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.32 , pp. 140-144
    • Garcia, L.S.1
  • 40
    • 79959350106 scopus 로고    scopus 로고
    • Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression
    • Koike, H., Iijima, M. & Chaki, S. Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression. Behav. Brain Res. 224, 107-111 (2011).
    • (2011) Behav. Brain Res. , vol.224 , pp. 107-111
    • Koike, H.1    Iijima, M.2    Chaki, S.3
  • 41
    • 77955891255 scopus 로고    scopus 로고
    • A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression
    • Diazgranados, N. et al. A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression. Arch Gen Psychiatry 67(8), 793-802 (2010).
    • (2010) Arch Gen Psychiatry , vol.67 , Issue.8 , pp. 793-802
    • Diazgranados, N.1


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