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Volumn 17, Issue 1, 2013, Pages 57-64

Redox markers and inflammation are differentially affected by atorvastatin, pravastatin or simvastatin administered before endotoxin-induced acute lung injury

Author keywords

Acute lung injury; Atorvastatin; Inflammation; Oxidative stress; Pravastatin; Simvastatin

Indexed keywords

ALANINE AMINOTRANSFERASE; ATORVASTATIN; BIOLOGICAL MARKER; CATALASE; INTERLEUKIN 6; MALONALDEHYDE; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; PRAVASTATIN; SIMVASTATIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84879195519     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.05.016     Document Type: Article
Times cited : (39)

References (57)
  • 1
    • 0036282589 scopus 로고    scopus 로고
    • The pulmonary physician in critical care 6: The pathogenesis of ALI/ARDS
    • DOI 10.1136/thorax.57.6.540
    • Bellingan GJ. The pulmonary physician in critical care 6: the pathogenesis of ALI/ARDS. Thorax 2002;57:540-6. (Pubitemid 34627988)
    • (2002) Thorax , vol.57 , Issue.6 , pp. 540-546
    • Bellingan, G.J.1
  • 2
    • 84862735568 scopus 로고    scopus 로고
    • Clinical review: Gene-based therapies for ALI/ARDS: Where are we now?
    • Devaney J, Contreras M, Laffey JG. Clinical review: gene-based therapies for ALI/ARDS: where are we now? Crit Care 2011;15:224.
    • (2011) Crit Care , vol.15 , pp. 224
    • Devaney, J.1    Contreras, M.2    Laffey, J.G.3
  • 4
    • 0029957727 scopus 로고    scopus 로고
    • Nitric oxide regulation of superoxide-dependent lung injury: Oxidant- protective actions of endogenously produced and exogenously administered nitric oxide
    • DOI 10.1016/0891-5849(95)02226-0
    • Gutierrez HH, Nieves B, Chumley P, Rivera A, Freeman BA. Nitric oxide regulation of superoxide-dependent lung injury: oxidant-protective actions of endogenously produced and exogenously administered nitric oxide. Free Radic Biol Med 1996;21: 43-52. (Pubitemid 26230404)
    • (1996) Free Radical Biology and Medicine , vol.21 , Issue.1 , pp. 43-52
    • Gutierrez, H.H.1    Nieves, B.2    Chumley, P.3    Rivera, A.4    Freeman, B.A.5
  • 7
    • 67349266761 scopus 로고    scopus 로고
    • Amelioration of pulmonary dysfunction and neutrophilic inflammation by PPAR gamma agonist in LPS-exposed guinea pigs
    • Sharma R, Kaundal RK, Sharma SS. Amelioration of pulmonary dysfunction and neutrophilic inflammation by PPAR gamma agonist in LPS-exposed guinea pigs. Pulm Pharmacol Ther 2009;22:183-9.
    • (2009) Pulm Pharmacol Ther , vol.22 , pp. 183-189
    • Sharma, R.1    Kaundal, R.K.2    Sharma, S.S.3
  • 11
    • 2642536741 scopus 로고    scopus 로고
    • Inflammation, immunity, and HMG-CoA reductase inhibitors: Statins as antiinflammatory agents?
    • Schonbeck U, Libby P. Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents? Circulation 2004;109:II18-26. (Pubitemid 38724152)
    • (2004) Circulation , vol.109 , Issue.21 SUPPL.
    • Schonbeck, U.1    Libby, P.2
  • 12
    • 0036235053 scopus 로고    scopus 로고
    • Antiinflammatory and immunomodulatory properties of statins
    • DOI 10.1385/IR:25:3:271
    • Shovman O, Levy Y, Gilburd B, Shoenfeld Y. Antiinflammatory and immunomodulatory properties of statins. Immunol Res 2002;25:271-85. (Pubitemid 34454717)
    • (2002) Immunologic Research , vol.25 , Issue.3 , pp. 271-285
    • Shovman, O.1    Levy, Y.2    Gilburd, B.3    Shoenfeld, Y.4
  • 13
    • 33751183978 scopus 로고    scopus 로고
    • Molecular basis of differences among statins and a comparison with antioxidant vitamins
    • Mason RP. Molecular basis of differences among statins and a comparison with antioxidant vitamins. Am J Cardiol 2006;98:34P-41P.
    • (2006) Am J Cardiol , vol.98
    • Mason, R.P.1
  • 14
    • 1242276306 scopus 로고    scopus 로고
    • Statins in atherosclerosis: Lipid-lowering agents with antioxidant capabilities
    • DOI 10.1016/S0021-9150(03)00239-9
    • Rosenson RS. Statins in atherosclerosis: lipid-lowering agents with antioxidant capabilities. Atherosclerosis 2004;173:1-12. (Pubitemid 38228462)
    • (2004) Atherosclerosis , vol.173 , Issue.1 , pp. 1-12
    • Rosenson, R.S.1
  • 15
    • 60749131372 scopus 로고    scopus 로고
    • Statins in endothelial signaling and activation
    • Jacobson JR. Statins in endothelial signaling and activation. Antioxid Redox Signal 2009;11:811-21.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 811-821
    • Jacobson, J.R.1
  • 16
    • 84864662279 scopus 로고    scopus 로고
    • Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms
    • Kumar A, Sharma N, Gupta A, Kalonia H, Mishra J. Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms. Brain Res 2012;1471:13-22.
    • (2012) Brain Res , vol.1471 , pp. 13-22
    • Kumar, A.1    Sharma, N.2    Gupta, A.3    Kalonia, H.4    Mishra, J.5
  • 17
    • 77954040082 scopus 로고    scopus 로고
    • Using pravastatin to improve the vascular reactivity in a mousemodel of soluble fms-like tyrosine kinase-1-induced preeclampsia
    • CostantineMM, Tamayo E, Lu F, Bytautiene E, Longo M,Hankins GD, et al. Using pravastatin to improve the vascular reactivity in a mousemodel of soluble fms-like tyrosine kinase-1-induced preeclampsia. Obstet Gynecol 2010;116:114-20.
    • (2010) Obstet Gynecol , vol.116 , pp. 114-120
    • Costantine, M.M.1    Tamayo, E.2    Lu, F.3    Bytautiene, E.4    Longo Mhankins, G.D.5
  • 18
    • 84857371918 scopus 로고    scopus 로고
    • Simvastatin improves morphological and functional recovery of sciatic nerve injury in Wistar rats
    • Xavier AM, Serafim KG, Higashi DT, Vanat N, Flaiban KK, Siqueira CP, et al. Simvastatin improves morphological and functional recovery of sciatic nerve injury in Wistar rats. Injury 2012;43:284-9.
    • (2012) Injury , vol.43 , pp. 284-289
    • Xavier, A.M.1    Serafim, K.G.2    Higashi, D.T.3    Vanat, N.4    Flaiban, K.K.5    Siqueira, C.P.6
  • 19
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 20
    • 84864013454 scopus 로고    scopus 로고
    • Time course of inflammation, oxidative stress and tissue damage induced by hyperoxia in mouse lungs
    • Nagato AC, Bezerra FS, Lanzetti M, Lopes AA, Silva MA, Porto LC, et al. Time course of inflammation, oxidative stress and tissue damage induced by hyperoxia in mouse lungs. Int J Exp Pathol; 2012;93:269-78.
    • (2012) Int J Exp Pathol , vol.93 , pp. 269-278
    • Nagato, A.C.1    Bezerra, F.S.2    Lanzetti, M.3    Lopes, A.A.4    Silva, M.A.5    Porto, L.C.6
  • 21
    • 0023463279 scopus 로고
    • Aspects of the structure, function, and applications of superoxide dismutase
    • Bannister JV, Bannister WH, Rotilio G. Aspects of the structure, function, and applications of superoxide dismutase. CRC Crit Rev Biochem 1987;22:111-80.
    • (1987) CRC Crit Rev Biochem , vol.22 , pp. 111-180
    • Bannister, J.V.1    Bannister, W.H.2    Rotilio, G.3
  • 22
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Methods Enzymol 1984;105:121-6.
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 23
    • 0027366166 scopus 로고
    • A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials
    • DOI 10.1016/0891-5849(93)90035-S
    • Draper HH, Squires EJ,Mahmoodi H,Wu J, Agarwal S, Hadley M. A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials. Free Radic Biol Med 1993;15:353-63. (Pubitemid 23283552)
    • (1993) Free Radical Biology and Medicine , vol.15 , Issue.4 , pp. 353-363
    • Draper, H.H.1    Squires, E.J.2    Mahmoodi, H.3    Wu, J.4    Agarwal, S.5    Hadley, M.6
  • 24
    • 0029114548 scopus 로고
    • Quantification of lipid peroxidation in tissue extracts based on Fe(III)xylenol orange complex formation
    • Hermes-Lima M, Willmore WG, Storey KB. Quantification of lipid peroxidation in tissue extracts based on Fe(III)xylenol orange complex formation. Free Radic Biol Med 1995;19:271-80.
    • (1995) Free Radic Biol Med , vol.19 , pp. 271-280
    • Hermes-Lima, M.1    Willmore, W.G.2    Storey, K.B.3
  • 25
    • 0024590274 scopus 로고
    • Determination of carbonyl groups in oxidatively modified proteins by reduction with tritiated sodium borohydride
    • DOI 10.1016/0003-2697(89)90077-8
    • Lenz AG, Costabel U, Shaltiel S, Levine RL. Determination of carbonyl groups in oxidatively modified proteins by reduction with tritiated sodium borohydride. Anal Biochem 1989;177:419-25. (Pubitemid 19088284)
    • (1989) Analytical Biochemistry , vol.177 , Issue.2 , pp. 419-425
    • Lenz, A.-G.1    Costabel, U.2    Shaltiel, S.3    Levine, R.L.4
  • 26
    • 0020550892 scopus 로고
    • Assay method for myeloperoxidase in human polymorphonuclear leukocytes
    • Suzuki K, Ota H, Sasagawa S, Sakatani T, Fujikura T. Assay method formyeloperoxidase in human polymorphonuclear leukocytes. Anal Biochem 1983;132:345-52. (Pubitemid 13048589)
    • (1983) Analytical Biochemistry , vol.132 , Issue.2 , pp. 345-352
    • Suzuki, K.1    Ota, H.2    Sasagawa, S.3
  • 27
    • 34248232009 scopus 로고    scopus 로고
    • Comparison of nitrite/nitrate concentration in human plasma and serum samples measured by the enzymatic batch Griess assay, ion-pairing HPLC and ion-trap GC-MS: The importance of a correct removal of proteins in the Griess assay
    • DOI 10.1016/j.jchromb.2007.02.003, PII S1570023207001006, Analysis of the L-Arginine/NO Pathway
    • Romitelli F, Santini SA, Chierici E, Pitocco D, Tavazzi B, Amorini AM, et al. Comparison of nitrite/nitrate concentration in human plasma and serum samples measured by the enzymatic batch Griess assay, ion-pairing HPLC and ion-trap GC-MS: the importance of a correct removal of proteins in the Griess assay. J Chromatogr B Analyt Technol Biomed Life Sci 2007;851:257-67. (Pubitemid 46720148)
    • (2007) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.851 , Issue.1-2 , pp. 257-267
    • Romitelli, F.1    Santini, S.A.2    Chierici, E.3    Pitocco, D.4    Tavazzi, B.5    Amorini, A.M.6    Lazzarino, G.7    Di Stasio, E.8
  • 28
    • 0035710746 scopus 로고    scopus 로고
    • -CT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402-8. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 30
    • 0022256369 scopus 로고
    • Analysis of the behavior of the respiratory system with constant inspiratory flow
    • Bates JH, Rossi A, Milic-Emili J. Analysis of the behavior of the respiratory system with constant inspiratory flow. J Appl Physiol 1985;58:1840-8. (Pubitemid 15013843)
    • (1985) Journal of Applied Physiology , vol.58 , Issue.6 , pp. 1840-1848
    • Bates, J.H.T.1    Rossi, A.2    Milic-Emili, J.3
  • 31
    • 0023747156 scopus 로고
    • Interrupter resistance elucidated by alveolar pressure measurement in open-chest normal dogs
    • Bates JH, Ludwig MS, Sly PD, Brown K, Martin JG, Fredberg JJ. Interrupter resistance elucidated by alveolar pressure measurement in open-chest normal dogs. J Appl Physiol 1988;65:408-14.
    • (1988) J Appl Physiol , vol.65 , pp. 408-414
    • Bates, J.H.1    Ludwig, M.S.2    Sly, P.D.3    Brown, K.4    Martin, J.G.5    Fredberg, J.J.6
  • 33
    • 41649093814 scopus 로고    scopus 로고
    • Lipopolysaccharide sensing an important factor in the innate immune response to Gram-negative bacterial infections: Benefits and hazards of LPS hypersensitivity
    • Freudenberg MA, Tchaptchet S, Keck S, Fejer G, Huber M, Schutze N, et al. Lipopolysaccharide sensing an important factor in the innate immune response to Gram-negative bacterial infections: benefits and hazards of LPS hypersensitivity. Immunobiology 2008;213:193-203.
    • (2008) Immunobiology , vol.213 , pp. 193-203
    • Freudenberg, M.A.1    Tchaptchet, S.2    Keck, S.3    Fejer, G.4    Huber, M.5    Schutze, N.6
  • 34
    • 78650043236 scopus 로고    scopus 로고
    • The value of the lipopolysaccharide-induced acute lung injury model in respiratory medicine
    • Chen H, Bai C, Wang X. The value of the lipopolysaccharide-induced acute lung injury model in respiratory medicine. Expert Rev Respir Med 2010;4:773-83.
    • (2010) Expert Rev Respir Med , vol.4 , pp. 773-783
    • Chen, H.1    Bai, C.2    Wang, X.3
  • 35
    • 33747649790 scopus 로고    scopus 로고
    • Pathophysiology of acute lung injury and the acute respiratory distress syndrome
    • DOI 10.1055/s-2006-948288
    • Ware LB. Pathophysiology of acute lung injury and the acute respiratory distress syndrome. Semin Respir Crit Care Med 2006;27:337-49. (Pubitemid 44272603)
    • (2006) Seminars in Respiratory and Critical Care Medicine , vol.27 , Issue.4 , pp. 337-349
    • Ware, L.B.1
  • 39
    • 3042638413 scopus 로고    scopus 로고
    • Simvastatin modulates TNF-induced adhesion molecules expression in human endothelial cells
    • DOI 10.1016/j.lfs.2004.03.005, PII S0024320504004163
    • Zapolska-Downar D, Siennicka A, Kaczmarczyk M, Kolodziej B, Naruszewicz M. Simvastatin modulates TNFalpha-induced adhesion molecules expression in human endothelial cells. Life Sci 2004;75:1287-302. (Pubitemid 38845028)
    • (2004) Life Sciences , vol.75 , Issue.11 , pp. 1287-1302
    • Zapolska-Downar, D.1    Siennicka, A.2    Kaczmarczyk, M.3    Kolodziej, B.4    Naruszewicz, M.5
  • 41
    • 84857637931 scopus 로고    scopus 로고
    • Residual cardiovascular risk despite optimal LDL cholesterol reduction with statins: The evidence etiology and therapeutic challenges
    • Sampson UK, Fazio S, Linton MF. Residual cardiovascular risk despite optimal LDL cholesterol reduction with statins: the evidence, etiology, and therapeutic challenges. Curr Atheroscler Rep; 2012;14:1-10.
    • (2012) Curr Atheroscler Rep , vol.14 , pp. 1-10
    • Sampson, U.K.1    Fazio, S.2    Linton, M.F.3
  • 42
    • 84858389340 scopus 로고    scopus 로고
    • Biomarkers in acute lung injury
    • Bhargava M, Wendt CH. Biomarkers in acute lung injury. Transl Res; 2012;159: 205-17.
    • (2012) Transl Res , vol.159 , pp. 205-217
    • Bhargava, M.1    Wendt, C.H.2
  • 43
    • 84856225815 scopus 로고    scopus 로고
    • The differential effect of statins on oxidative stress and endothelial function: Atorvastatin versus pravastatin
    • Murrow JR, Sher S, Ali S, Uphoff I, Patel R, Porkert M, et al. The differential effect of statins on oxidative stress and endothelial function: atorvastatin versus pravastatin. J Clin Lipidol; 2012;6:42-9.
    • (2012) J Clin Lipidol , vol.6 , pp. 42-49
    • Murrow, J.R.1    Sher, S.2    Ali, S.3    Uphoff, I.4    Patel, R.5    Porkert, M.6
  • 44
    • 0033398822 scopus 로고    scopus 로고
    • Simvastatin inhibits leukocyte-endothelial cell interactions and protects against inflammatory processes in normocholesterolemic rats
    • Pruefer D, Scalia R, Lefer AM. Simvastatin inhibits leukocyte-endothelial cell interactions and protects against inflammatory processes in normocholesterolemic rats. Arterioscler Thromb Vasc Biol 1999;19:2894-900. (Pubitemid 30029815)
    • (1999) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.19 , Issue.12 , pp. 2894-2900
    • Pruefer, D.1    Scalia, R.2    Lefer, A.M.3
  • 45
    • 33750606896 scopus 로고    scopus 로고
    • Neutrophil superoxide anion generation during atorvastatin and fluvastatin therapy used in coronary heart disease primary prevention
    • DOI 10.1097/01.fjc.0000246150.52382.07, PII 0000534420061000000002
    • Kowalski J, Barylski M, Banach M, Grycewicz J, Irzmanski R, Pawlicki L. Neutrophil superoxide anion generation during atorvastatin and fluvastatin therapy used in coronary heart disease primary prevention. J Cardiovasc Pharmacol 2006;48: 143-7. (Pubitemid 44691215)
    • (2006) Journal of Cardiovascular Pharmacology , vol.48 , Issue.4 , pp. 143-147
    • Kowalski, J.1    Barylski, M.2    Banach, M.3    Grycewicz, J.4    Irzmanski, R.5    Pawlicki, L.6
  • 46
    • 19444379395 scopus 로고    scopus 로고
    • Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses
    • DOI 10.1667/RR3302
    • Gaugler MH, Vereycken-Holler V, Squiban C, Vandamme M, Vozenin-Brotons MC, BenderitterM. Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses. Radiat Res 2005;163:479-87. (Pubitemid 41490643)
    • (2005) Radiation Research , vol.163 , Issue.5 , pp. 479-487
    • Gaugler, M.-H.1    Vereycken-Holler, V.2    Squiban, C.3    Vandamme, M.4    Vozenin-Brotons, M.-C.5    Benderitter, M.6
  • 47
    • 77953807933 scopus 로고    scopus 로고
    • Statins and inflammation: An update
    • Quist-Paulsen P. Statins and inflammation: an update. Curr Opin Cardiol; 2010;25:399-405.
    • (2010) Curr Opin Cardiol , vol.25 , pp. 399-405
    • Quist-Paulsen, P.1
  • 48
    • 84859260939 scopus 로고    scopus 로고
    • Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells
    • Iwata A, Shirai R, Ishii H, Kushima H, Otani S, Hashinaga K, et al. Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells. Clin Exp Immunol 2012;168:234-40.
    • (2012) Clin Exp Immunol , vol.168 , pp. 234-240
    • Iwata, A.1    Shirai, R.2    Ishii, H.3    Kushima, H.4    Otani, S.5    Hashinaga, K.6
  • 49
    • 84869467720 scopus 로고    scopus 로고
    • Restoration of alveolar type II cell function contributes to simvastatin-induced attenuation of lung ischemiareperfusion injury
    • Wu Y, Lv J, Feng D, Jiang F, Fan X, Zhang Z, et al. Restoration of alveolar type II cell function contributes to simvastatin-induced attenuation of lung ischemiareperfusion injury. Int J Mol Med 2012;30:1294-306.
    • (2012) Int J Mol Med , vol.30 , pp. 1294-1306
    • Wu, Y.1    Lv, J.2    Feng, D.3    Jiang, F.4    Fan, X.5    Zhang, Z.6
  • 50
    • 84907275421 scopus 로고    scopus 로고
    • Inhibitory effects of simvastatin on staphylococcus aureus lipoteichoic acid-induced inflammation in human alveolar macrophages
    • Wu BQ, Luo JM,Wang YH, Shi YF, Liu H, Ba JH, et al. Inhibitory effects of simvastatin on staphylococcus aureus lipoteichoic acid-induced inflammation in human alveolar macrophages. Clin Exp Med 2013, http://dx.doi.org/10.1007/s10238- 013-0231-z.
    • (2013) Clin Exp Med
    • Wu, B.Q.1    Luo Jmwang, Y.H.2    Shi, Y.F.3    Liu, H.4    Ba, J.H.5
  • 51
    • 80054698411 scopus 로고    scopus 로고
    • Endotoxin-induced cardiovascular dysfunction in mice: Effect of simvastatin
    • Suda K, Eom J, Jaw JE, Mui T, Bai N, Or C, et al. Endotoxin-induced cardiovascular dysfunction in mice: effect of simvastatin. J Appl Physiol; 2011;111:1118-24.
    • (2011) J Appl Physiol , vol.111 , pp. 1118-1124
    • Suda, K.1    Eom, J.2    Jaw, J.E.3    Mui, T.4    Bai, N.5    Or, C.6
  • 52
    • 33747073147 scopus 로고    scopus 로고
    • Protective effects of pravastatin in murine lipopolysaccharideinduced acute lung injury
    • YaoHW, Mao LG, Zhu JP. Protective effects of pravastatin in murine lipopolysaccharideinduced acute lung injury. Clin Exp Pharmacol Physiol 2006;33:793-7.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 793-797
    • Yao, H.W.1    Mao, L.G.2    Zhu, J.P.3
  • 53
    • 84862201630 scopus 로고    scopus 로고
    • Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation
    • Grommes J, Vijayan S, Drechsler M, Hartwig H, Morgelin M, Dembinski R, et al. Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation. PLoS One; 2012;7:e38917.
    • (2012) PLoS One , vol.7
    • Grommes, J.1    Vijayan, S.2    Drechsler, M.3    Hartwig, H.4    Morgelin, M.5    Dembinski, R.6
  • 54
    • 80051534221 scopus 로고    scopus 로고
    • Long-term simvastatin attenuates lung injury and oxidative stress in murine acute lung injury models induced by oleic Acid and endotoxin
    • Altintas ND, Atilla P, Iskit AB, Topeli A. Long-term simvastatin attenuates lung injury and oxidative stress in murine acute lung injury models induced by oleic Acid and endotoxin. Respir Care; 2011;56:1156-63.
    • (2011) Respir Care , vol.56 , pp. 1156-1163
    • Altintas, N.D.1    Atilla, P.2    Iskit, A.B.3    Topeli, A.4
  • 55
    • 0347419370 scopus 로고    scopus 로고
    • Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA
    • Passi S, Stancato A, Aleo E, Dmitrieva A, Littarru GP. Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA. Biofactors 2003;18:113-24. (Pubitemid 38030705)
    • (2003) BioFactors , vol.18 , Issue.1-4 , pp. 113-124
    • Passi, S.1    Stancato, A.2    Aleo, E.3    Dmitrieva, A.4    Littarru, G.P.5
  • 56
    • 79952247425 scopus 로고    scopus 로고
    • Acute lung injury and alveolar epithelial function
    • Uchida T. Acute lung injury and alveolar epithelial function. J Anesth; 2011;25:152-4.
    • (2011) J Anesth , vol.25 , pp. 152-154
    • Uchida, T.1
  • 57
    • 79952240186 scopus 로고    scopus 로고
    • A randomized clinical trial of hydroxymethylglutaryl- coenzymea reductase inhibition for acute lung injury (The HARP Study)
    • Craig TR, Duffy MJ, Shyamsundar M, McDowell C, O'Kane CM, Elborn JS, et al. A randomized clinical trial of hydroxymethylglutaryl- coenzymea reductase inhibition for acute lung injury (The HARP Study). Am J Respir Crit Care Med; 2011;183:620-6.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 620-626
    • Craig, T.R.1    Duffy, M.J.2    Shyamsundar, M.3    McDowell, C.4    O'Kane, C.M.5    Elborn, J.S.6


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