Endotoxin-induced acute lung injury is dependent upon oxidative response

Inhalation Toxicology

Volumn 23, Issue 14, 2011, Pages 918-926

  Lima Trajano, Eduardo Tavares ^a   Sternberg, Cinthya ^b   Caetano, Maurício ^b   Santos Silva, Marco Aurélio ^a   Porto, Lus Cristóvão ^a   Santos, Juliana Carvalho ^c   Ribeiro, Marcelo Lima ^c   Magalhães, Clarissa Bichara ^d   Zin, Walter Arajo ^d   Benjamim, Cláudia Farias ^d   Valença, Samuel Santos ^d  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO NACIONAL DE CÂNCER   (Brazil)

^c Unidade Integrada de Farmacologia e Gastroenterologia USF   (Brazil)

^d FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Acute lung injury; Inflammatory response; Lipopolysaccharide; Lung histology; Oxidative stress; Pulmonary mechanics

Indexed keywords

ACETYLCYSTEINE; CARBONYL DERIVATIVE; CATALASE; CYCLOOXYGENASE 2; GELATIN; GELATINASE A; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE; NITRITE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSISTED VENTILATION; CELL FUNCTION; CELL STRUCTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; INFLAMMATION; LEUKOCYTE; LUNG ALVEOLUS; LUNG COMPLIANCE; LUNG PRESSURE; LUNG VOLUME; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; ZYMOGRAPHY;

ACETYLCYSTEINE; ACUTE LUNG INJURY; ANIMALS; ANTIOXIDANTS; BRONCHOALVEOLAR LAVAGE FLUID; CATALASE; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GLUTATHIONE; LIPOPOLYSACCHARIDES; LUNG; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED C57BL; NITRITES; OXIDATION-REDUCTION; OXIDATIVE STRESS; PEROXIDASE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 82655169635     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958378.2011.625994     Document Type: Article

References (38)

1. Aebi H. 1984. Catalase in vitro. Meth Enzymol 105:121-126.
2. Bannister JV, Calabrese L. 1987. Assays for superoxide dismutase. Methods Biochem Anal 32:279-312.
3. Bast A, Weseler AR, Haenen GR, den Hartog GJ. 2010. Oxidative stress and antioxidants in interstitial lung disease. Curr Opin Pulm Med 16:516-520.
4. Bates JH, Ludwig MS, Sly PD, Brown K, Martin JG, Fredberg JJ. 1988. Interrupter resistance elucidated by alveolar pressure measurement in open-chest normal dogs. J Appl Physiol 65:408-414.
5. Bates JH, Rossi A, Milic-Emili J. 1985. Analysis of the behavior of the respiratory system with constant inspiratory flow. J Appl Physiol 58:1840-1848.
6. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
7. Burchardi H. 1996. New strategies in mechanical ventilation for acute lung injury. Eur Respir J 9:1063-1072.
8. Chan E, Obaid L, Johnson ST, Bigam DL, Cheung PY. 2007. N-acetylcysteine administration improves platelet aggregation in hypoxia-reoxygenation injury. Proc West Pharmacol Soc 50:53-57.
9. Chow CW, Herrera Abreu MT, Suzuki T, Downey GP. 2003. Oxidative stress and acute lung injury. Am J Respir Cell Mol Biol 29:427-431.
10. Cross CE, Eiserich JP. 2004. Oxidative stress in acute lung injury: Déja vu or something new? Crit Care Med 32:892-893.
11. Danielsen PH, Loft S, Jacobsen NR, Jensen KA, Autrup H, Ravanat JL, Wallin H, Møller P. 2010. Oxidative stress, inflammation, and DNA damage in rats after intratracheal instillation or oral exposure to ambient air and wood smoke particulate matter. Toxicol Sci 118:574-585.
12. Dodd S, Dean O, Copolov DL, Malhi GS, Berk M. 2008. N-acetylcysteine for antioxidant therapy: Pharmacology and clinical utility. Expert Opin Biol Ther 8:1955-1962.
13. Draper HH, Hadley M. 1990. Malondialdehyde determination as index of lipid peroxidation. Meth Enzymol 186:421-431.
14. Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR. 1982. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem 126:131-138.
15. Hoffer E, Baum Y, Tabak A, Taitelman U. 1996. N-acetylcysteine increases the glutathione content and protects rat alveolar type II cells against paraquat-induced cytotoxicity. Toxicol Lett 84:7-12.
16. Huet O, Dupic L, Harrois A, Duranteau J. 2011. Oxidative stress and endothelial dysfunction during sepsis. Front Biosci 16:1986-1995.
17. Isik B, Ceylan A, Isik R. 2007. Oxidative stress in smokers and nonsmokers. Inhal Toxicol 19:767-769.
18. Karageuzyan KG. 2005. Oxidative stress in the molecular mechanism of pathogenesis at different diseased states of organism in clinics and experiment. Curr Drug Targets Inflamm Allergy 4:85-98.
19. Kuebler WM, Abels C, Schuerer L, Goetz AE. 1996. Measurement of neutrophil content in brain and lung tissue by a modified myeloperoxidase assay. Int J Microcirc Clin Exp 16:89-97.
20. Lanzetti M, Bezerra FS, Romana-Souza B, Brando-Lima AC, Koatz VL, Porto LC, Valenca SS. 2008. Mate tea reduced acute lung inflammation in mice exposed to cigarette smoke. Nutrition 24:375-381.
21. Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz AG, Ahn BW, Shaltiel S, Stadtman ER. 1990. Determination of carbonyl content in oxidatively modified proteins. Meth Enzymol 186:464-478.
22. Livak KJ, Flood SJ, Marmaro J, Giusti W, Deetz K. 1995. Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization. PCR Methods Appl 4:357-362.
23. Magalhães CB, Riva DR, DePaula LJ, Brando-Lima A, Koatz VL, Leal- Cardoso JH, Zin WA, Faffe DS. 2010. In vivo anti-inflammatory action of eugenol on lipopolysaccharide-induced lung injury. J Appl Physiol 108:845-851.
24. Matute-Bello G, Martin TR. 2003. Science review: Apoptosis in acute lung injury. Crit Care 7:355-358.
25. Mazzoli-Rocha F, Fernandes S, Einicker-Lamas M, Zin WA. 2010. Roles of oxidative stress in signaling and inflammation induced by particulate matter. Cell Biol Toxicol 26:481-498.
26. Mohamed MR, McFadden G. 2009. NFkB inhibitors: Strategies from poxviruses. Cell Cycle 8:3125-3132.
27. Mortola JP, Matsuoka T. 1993. Interaction between CO2 production and ventilation in the hypoxic kitten. J Appl Physiol 74:905-910.
28. Parasassi T, Brunelli R, Costa G, De Spirito M, Krasnowska E, Lundeberg T, Pittaluga E, Ursini F. 2010. Thiol redox transitions in cell signaling: A lesson from N-acetylcysteine. ScientificWorldJournal 10:1192-1202.
29. Pires KM, Bezerra FS, Machado MN, Zin WA, Porto LC, Valença SS. 2011. N-(2-mercaptopropionyl)-glycine but not allopurinol prevented cigarette smoke-induced alveolar enlargement in mouse. Respir Physiol Neurobiol 175:322-330.
30. Rahman I, Adcock IM. 2006. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Respir J 28:219-242.
31. Rose L. 2010. Clinical application of ventilator modes: Ventilatory strategies for lung protection. Aust Crit Care 23:71-80.
32. Saldiva PH, Zin WA, Santos RL, Eidelman DH, Milic-Emili J. 1992. Alveolar pressure measurement in open-chest rats. J Appl Physiol 72:302-306.
33. Teixeira KC, Soares FS, Rocha LG, Silveira PC, Silva LA, Valença SS, Dal Pizzol F, Streck EL, Pinho RA. 2008. Attenuation of bleomycininduced lung injury and oxidative stress by N-acetylcysteine plus deferoxamine. Pulm Pharmacol Ther 21:309-316.
34. Valença SS, da Hora K, Castro P, Moraes VG, Carvalho L, Porto LC. 2004. Emphysema and metalloelastase expression in mouse lung induced by cigarette smoke. Toxicol Pathol 32:351-356.
35. Valença SS, Pimenta WA, Rueff-Barroso CR, Ferreira TS, Resende AC, Moura RS, Porto LC. 2009. Involvement of nitric oxide in acute lung inflammation induced by cigarette smoke in the mouse. Nitric Oxide 20:175-181.
36. Valenca SS, Silva Bezerra F, Lopes AA, Romana-Souza B, Marinho Cavalcante MC, Lima AB, Gonçalves Koatz VL, Porto LC. 2008. Oxidative stress in mouse plasma and lungs induced by cigarette smoke and lipopolysaccharide. Environ Res 108:199-204.
37. Ward PA. 2010. Oxidative stress: Acute and progressive lung injury. Ann N Y Acad Sci 1203:53-59.
38. Zafarullah M, Li WQ, Sylvester J, Ahmad M. 2003. Molecular mechanisms of N-acetylcysteine actions. Cell Mol Life Sci 60:6-20.