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Volumn 2, Issue 3, 2012, Pages 318-340

Development of a fish cell biosensor system for genotoxicity detection based on DNA damage-induced trans-activation of p21 gene expression

Author keywords

Fish cells; Genotoxicity; Luciferase; P21; P53; Trans activation

Indexed keywords

BIOSENSORS; CELL SIGNALING; CYTOLOGY; DAMAGE DETECTION; FISH; GENE EXPRESSION; MAMMALS; METABOLISM; SODIUM COMPOUNDS;

EID: 84879192739     PISSN: None     EISSN: 20796374     Source Type: Journal    
DOI: 10.3390/bios2030318     Document Type: Article
Times cited : (13)

References (74)
  • 1
    • 0029014067 scopus 로고
    • Fish micronuclei for assessing genotoxicity in water
    • Al-Sabti, K.; Metcalfe, C.D. Fish micronuclei for assessing genotoxicity in water. Mutat. Res. 1995, 343, 121-135.
    • (1995) Mutat. Res. , vol.343 , pp. 121-135
    • Al-Sabti, K.1    Metcalfe, C.D.2
  • 3
    • 1942510615 scopus 로고    scopus 로고
    • On the relevance of genotoxicity for fish populations I: Effects of a model genotoxicant on zebrafish (Danio rerio) in a complete life-cycle test
    • Diekmann, M.; Hultsch, V.; Nagel, R. On the relevance of genotoxicity for fish populations I: Effects of a model genotoxicant on zebrafish (Danio rerio) in a complete life-cycle test. Aquat. Toxicol. 2004, 68, 13-26.
    • (2004) Aquat. Toxicol. , vol.68 , pp. 13-26
    • Diekmann, M.1    Hultsch, V.2    Nagel, R.3
  • 5
    • 61549129310 scopus 로고    scopus 로고
    • In vitro and in vivo acute toxicity of fenpyroximate to flounder Paralichthys olivaceus and its gill cell line FG
    • Na, N.; Guo, H.R.; Zhang, S.C.; Li, Z.J.; Yin, L.C. In vitro and in vivo acute toxicity of fenpyroximate to flounder Paralichthys olivaceus and its gill cell line FG. Aquat. Toxicol. 2009, 92, 76-85.
    • (2009) Aquat. Toxicol. , vol.92 , pp. 76-85
    • Na, N.1    Guo, H.R.2    Zhang, S.C.3    Li, Z.J.4    Yin, L.C.5
  • 6
    • 77957019145 scopus 로고    scopus 로고
    • Evaluation of cytotoxicity, genotoxicity and teratogenicity of marine sediments from Qingdao coastal areas using in vitro fish cell assay, comet assay and zebrafish embryo test
    • Yang, F.; Zhang, Q.Q.; Guo, H.R.; Zhang, S.C. Evaluation of cytotoxicity, genotoxicity and teratogenicity of marine sediments from Qingdao coastal areas using in vitro fish cell assay, comet assay and zebrafish embryo test. Toxicol. Vitr. 2010, 24, 2003-2011.
    • (2010) Toxicol. Vitr. , vol.24 , pp. 2003-2011
    • Yang, F.1    Zhang, Q.Q.2    Guo, H.R.3    Zhang, S.C.4
  • 7
    • 0025970844 scopus 로고
    • Cytotoxicity and genotoxicity assays with cultured fish cells: A review
    • Babich, H.; Borenfreund, E. Cytotoxicity and genotoxicity assays with cultured fish cells: A review. Toxicol. Vitr. 1991, 5, 91-100.
    • (1991) Toxicol. Vitr. , vol.5 , pp. 91-100
    • Babich, H.1    Borenfreund, E.2
  • 8
  • 9
    • 0021262222 scopus 로고
    • Comparisons of the radiosensitivity of three goldfish cell lines using short term endpoints
    • Mitani, H. Comparisons of the radiosensitivity of three goldfish cell lines using short term endpoints. Int. J. Radiat. Biol. 1984, 45, 637-643.
    • (1984) Int. J. Radiat. Biol. , vol.45 , pp. 637-643
    • Mitani, H.1
  • 10
    • 33745178831 scopus 로고    scopus 로고
    • Comparative overview of current international strategies and guidelines for genetic toxicology testing for regulatory purposes
    • Cimino, M.C. Comparative overview of current international strategies and guidelines for genetic toxicology testing for regulatory purposes. Environ. Mol. Mutagen. 2006, 47, 362-390.
    • (2006) Environ. Mol. Mutagen. , vol.47 , pp. 362-390
    • Cimino, M.C.1
  • 11
    • 0036222336 scopus 로고    scopus 로고
    • Genotoxicity testing, a regulatory requirement for drug discovery and development: Impact of ICH guidelines
    • Jena, G.B.; Kaul, C.L.; Ramarao, P. Genotoxicity testing, a regulatory requirement for drug discovery and development: Impact of ICH guidelines. Indian J. Pharmacol. 2002, 34, 86-99.
    • (2002) Indian J. Pharmacol. , vol.34 , pp. 86-99
    • Jena, G.B.1    Kaul, C.L.2    Ramarao, P.3
  • 12
    • 0016685233 scopus 로고
    • Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test
    • Ames, B.N.; Mccann, J.; Yamasaki, E. Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test. Mutat. Res. 1975, 31, 347-364.
    • (1975) Mutat. Res. , vol.31 , pp. 347-364
    • Ames, B.N.1    Mccann, J.2    Yamasaki, E.3
  • 14
    • 0030989340 scopus 로고    scopus 로고
    • The VITOTOX® test, a SOS bioluminescence Salmonella typhimurium test to measure genotoxicity kinetics
    • Vanderlelie, D.; Regniers, L.; Borremans, B.; Provoost, A.; Verschaeve, L. The VITOTOX® test, a SOS bioluminescence Salmonella typhimurium test to measure genotoxicity kinetics. Mutat. Res. 1997, 389, 279-290.
    • (1997) Mutat. Res. , vol.389 , pp. 279-290
    • Vanderlelie, D.1    Regniers, L.2    Borremans, B.3    Provoost, A.4    Verschaeve, L.5
  • 15
    • 0025951750 scopus 로고
    • A microplate version of the SOS/umu-test for rapid detection of genotoxins and genotoxic potentials of environmental samples
    • Reifferscheid, G.; Heil, J.; Oda, Y.; Zahn, R.K. A microplate version of the SOS/umu-test for rapid detection of genotoxins and genotoxic potentials of environmental samples. Mutat. Res. 1991, 253, 215-222.
    • (1991) Mutat. Res. , vol.253 , pp. 215-222
    • Reifferscheid, G.1    Heil, J.2    Oda, Y.3    Zahn, R.K.4
  • 16
    • 67349285374 scopus 로고    scopus 로고
    • Evaluation of the VitotoxTM and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development
    • Westerink, W.M.A.; Stevenson, J.C.R.; Lauwers, A.; Griffioen, G.; Horbach, G.J.; Schoonen, W.G.E.J. Evaluation of the VitotoxTM and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development. Mutat. Res. 2009, 676, 113-130.
    • (2009) Mutat. Res. , vol.676 , pp. 113-130
    • Westerink, W.M.A.1    Stevenson, J.C.R.2    Lauwers, A.3    Griffioen, G.4    Horbach, G.J.5    Schoonen, W.G.E.J.6
  • 17
    • 1542504727 scopus 로고    scopus 로고
    • Detecting carcinogens with the yeast DEL assay
    • Brennan, R.J.; Schiestl, R.H. Detecting carcinogens with the yeast DEL assay. Methods Mol. Biol. 2004, 262, 111-124.
    • (2004) Methods Mol. Biol. , vol.262 , pp. 111-124
    • Brennan, R.J.1    Schiestl, R.H.2
  • 19
    • 40849099992 scopus 로고    scopus 로고
    • A novel yeast-bassed tool to detect mutagenic and recombinogenic effects simultaneously
    • Schafer, B.; Neffgen, A.; Klinner, U. A novel yeast-bassed tool to detect mutagenic and recombinogenic effects simultaneously. Mutat. Res. 2008, 652, 20-29.
    • (2008) Mutat. Res. , vol.652 , pp. 20-29
    • Schafer, B.1    Neffgen, A.2    Klinner, U.3
  • 20
    • 0033984224 scopus 로고    scopus 로고
    • Application of yeast cells transformed with GFP expression constructs containing the RAD54 or RNR2 promoter as a test for the genotoxic potential of chemical substances
    • Afanassiev, V.; Sefton, M.; Anantachaiyong, T.; Barker, G.; Walmsley, R.; Wölfl, S. Application of yeast cells transformed with GFP expression constructs containing the RAD54 or RNR2 promoter as a test for the genotoxic potential of chemical substances. Mutat. Res. 2000, 464, 297-308.
    • (2000) Mutat. Res. , vol.464 , pp. 297-308
    • Afanassiev, V.1    Sefton, M.2    Anantachaiyong, T.3    Barker, G.4    Walmsley, R.5    Wölfl, S.6
  • 22
    • 0031431109 scopus 로고    scopus 로고
    • Green fluorescence protein as a reporter for the DNA damage-induced gene RAD54 in Saccharomyces cerevisiae
    • Walmsley, R.M.; Billinton, N.; Heyer, W.-D. Green fluorescence protein as a reporter for the DNA damage-induced gene RAD54 in Saccharomyces cerevisiae. Yeast 1997, 13, 1535-1545.
    • (1997) Yeast , vol.13 , pp. 1535-1545
    • Walmsley, R.M.1    Billinton, N.2    Heyer, W.-D.3
  • 23
    • 34447631687 scopus 로고    scopus 로고
    • The utilization of a Saccharomyces cerevisiae HUG1P-GFP promoter-reporter construct for the selective detection of DNA damage
    • Benton, M.G.; Glasser, N.R.; Palecek, S.P. The utilization of a Saccharomyces cerevisiae HUG1P-GFP promoter-reporter construct for the selective detection of DNA damage. Mutat. Res. 2007, 633, 21-34.
    • (2007) Mutat. Res. , vol.633 , pp. 21-34
    • Benton, M.G.1    Glasser, N.R.2    Palecek, S.P.3
  • 25
    • 36049046631 scopus 로고    scopus 로고
    • An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC)-including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds
    • Knight, A.W.; Billinton, N.; Cahill, P.A.; Scott, A.; Harvey, J.S.; Roberts, K.J.; Tweats, D.J.; Keenan, P.O.; Walmsley, R.M. An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC)-including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds. Mutagenesis 2007, 22, 409-416.
    • (2007) Mutagenesis , vol.22 , pp. 409-416
    • Knight, A.W.1    Billinton, N.2    Cahill, P.A.3    Scott, A.4    Harvey, J.S.5    Roberts, K.J.6    Tweats, D.J.7    Keenan, P.O.8    Walmsley, R.M.9
  • 26
    • 49649129964 scopus 로고    scopus 로고
    • Development of a highthroughput yeast-based assay for detection of metabolically activated genotoxins
    • Liu, X.; Kramer, J.A.; Swaffield, J.C.; Hu, Y.; Chai, G.; Wilson, A.G.E. Development of a highthroughput yeast-based assay for detection of metabolically activated genotoxins. Mutat. Res. 2008, 653, 63-69.
    • (2008) Mutat. Res. , vol.653 , pp. 63-69
    • Liu, X.1    Kramer, J.A.2    Swaffield, J.C.3    Hu, Y.4    Chai, G.5    Wilson, A.G.E.6
  • 28
    • 44449170694 scopus 로고    scopus 로고
    • Ecotoxicological applications and significance of the comet assay
    • Jha, A.N. Ecotoxicological applications and significance of the comet assay. Mutagenesis 2008, 23, 207-221.
    • (2008) Mutagenesis , vol.23 , pp. 207-221
    • Jha, A.N.1
  • 29
    • 0023919963 scopus 로고    scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh, N.P.; McCoy, M.T.; Tice, R.R.; Schneider, E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 1998, 175, 184-191.
    • (1998) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 30
    • 0029175305 scopus 로고
    • Gene mutation assays in mammalian cells
    • Clements, J. Gene mutation assays in mammalian cells. Methods Mol. Biol. 1995, 43, 277-286.
    • (1995) Methods Mol. Biol. , vol.43 , pp. 277-286
    • Clements, J.1
  • 31
    • 27744581861 scopus 로고    scopus 로고
    • Genotoxicity test system based on p53R2 gene expression in human cells: Examination with 80 chemicals
    • Ohno, K.; Tanaka-Azuma, Y.; Yoneda, Y.; Yamada, T.G. Genotoxicity test system based on p53R2 gene expression in human cells: Examination with 80 chemicals. Mutat. Res. 2005, 588, 47-57.
    • (2005) Mutat. Res. , vol.588 , pp. 47-57
    • Ohno, K.1    Tanaka-Azuma, Y.2    Yoneda, Y.3    Yamada, T.G.4
  • 32
    • 53249113140 scopus 로고    scopus 로고
    • A genotoxicity test system based on p53R2 gene expression in human cells: Assessment of its reactivity to various classes of genotoxic chemicals
    • Ohno, K.; Ishihata, K.; Ohno, K.; Tanaka-Azuma, Y.; Yamada, T. A genotoxicity test system based on p53R2 gene expression in human cells: Assessment of its reactivity to various classes of genotoxic chemicals. Mutat. Res. 2008, 656, 27-35.
    • (2008) Mutat. Res. , vol.656 , pp. 27-35
    • Ohno, K.1    Ishihata, K.2    Ohno, K.3    Tanaka-Azuma, Y.4    Yamada, T.5
  • 34
    • 33746309471 scopus 로고    scopus 로고
    • High-Specificity and high-sensitivity genotoxicity assessment in a human cell line: Validation of the GreenScreen HC GADD45a-GFP genotoxicity assay
    • Hastwell, P.W.; Chai, L.-L.; Roberts, K.J.; Webster, T.W.; Harvey, J.S.; Rees, R.W.; Walmsley, R.M. High-Specificity and high-sensitivity genotoxicity assessment in a human cell line: Validation of the GreenScreen HC GADD45a-GFP genotoxicity assay. Mutat. Res. 2006, 607, 160-175.
    • (2006) Mutat. Res. , vol.607 , pp. 160-175
    • Hastwell, P.W.1    Chai, L.-L.2    Roberts, K.J.3    Webster, T.W.4    Harvey, J.S.5    Rees, R.W.6    Walmsley, R.M.7
  • 36
    • 58849156016 scopus 로고    scopus 로고
    • Development and validation of a higher throughput screening approach to genotoxicity testing using the GADD45a-GFP GreenScreen HC assay
    • Knight, A.W.; Birrell, L.; Walmsley, R.M. Development and validation of a higher throughput screening approach to genotoxicity testing using the GADD45a-GFP GreenScreen HC assay. J. Biomol. Screen. 2009, 14, 16-30.
    • (2009) J. Biomol. Screen. , vol.14 , pp. 16-30
    • Knight, A.W.1    Birrell, L.2    Walmsley, R.M.3
  • 37
    • 0027970713 scopus 로고
    • DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cipl in normal human fibroblasts
    • Leonardo, A.D.; Linke, S.P.; Clarkin, K.; Wahl, G.M. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cipl in normal human fibroblasts. Genes Dev. 1994, 8, 2540-2551.
    • (1994) Genes Dev , vol.8 , pp. 2540-2551
    • Leonardo, A.D.1    Linke, S.P.2    Clarkin, K.3    Wahl, G.M.4
  • 38
    • 0028849274 scopus 로고
    • p21 is necessary for the p53-mediated G1 arrest in human cancer cells
    • Waldman, T.; Kinzler, K.W.; Vogelstein, B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res. 1995, 55, 5187-5190.
    • (1995) Cancer Res , vol.55 , pp. 5187-5190
    • Waldman, T.1    Kinzler, K.W.2    Vogelstein, B.3
  • 39
    • 77950174369 scopus 로고    scopus 로고
    • Development of human cell biosensor system for genotoxicity detection based on DNA damage-induced gene expression
    • Zager, V.; Cemazar, M.; Hreljac, I.; Lah, T.T.; Sersa, G.; Filipic, M. Development of human cell biosensor system for genotoxicity detection based on DNA damage-induced gene expression. Radiol. Oncol. 2010, 44, 42-51.
    • (2010) Radiol. Oncol. , vol.44 , pp. 42-51
    • Zager, V.1    Cemazar, M.2    Hreljac, I.3    Lah, T.T.4    Sersa, G.5    Filipic, M.6
  • 40
    • 78649863340 scopus 로고    scopus 로고
    • Cytotoxicity and genotoxicity of polyethylenimine and nickel chloride in red sea bream(Pagrosomus major)fin cell line RSBF
    • Guo, H.R.; Zhang, S.C. Cytotoxicity and genotoxicity of polyethylenimine and nickel chloride in red sea bream(Pagrosomus major)fin cell line RSBF. Chin. J. Oceanol. Limnol. 2002, 20, 323-331.
    • (2002) Chin. J. Oceanol. Limnol. , vol.20 , pp. 323-331
    • Guo, H.R.1    Zhang, S.C.2
  • 41
    • 0034756182 scopus 로고    scopus 로고
    • In vitro cytotoxicity of the organophosphorus pesticide parathion to FG-9307 cells
    • Li, H.Y.; Zhang, S.C. In vitro cytotoxicity of the organophosphorus pesticide parathion to FG-9307 cells. Toxicol. Vitr. 2001, 15, 643-647.
    • (2001) Toxicol. Vitr. , vol.15 , pp. 643-647
    • Li, H.Y.1    Zhang, S.C.2
  • 42
    • 61549084124 scopus 로고    scopus 로고
    • Study on the acute toxicity and genotoxicity of herbicide butachlor in flounder, Paralichihys olivaceus, and flounder gill (FG) cells
    • Yin, L.C.; Guo, H.R.; Zhang, S.C.; Wang, J. Study on the acute toxicity and genotoxicity of herbicide butachlor in flounder, Paralichihys olivaceus, and flounder gill (FG) cells. J. Ocean Univ. China 2007, 37, 167-171.
    • (2007) J. Ocean Univ. China , vol.37 , pp. 167-171
    • Yin, L.C.1    Guo, H.R.2    Zhang, S.C.3    Wang, J.4
  • 43
    • 61549126414 scopus 로고    scopus 로고
    • In vitro acute cytotoxicity of abamectin to the gill cell line of flounder Paralichthy olivaceus
    • Xu, Y.Y.; Guo, H.R.; Qin, X.; SU, F.; Yin, L.C. In vitro acute cytotoxicity of abamectin to the gill cell line of flounder Paralichthy olivaceus. J. Ocean Univ. China 2007, 6, 369-372.
    • (2007) J. Ocean Univ. China , vol.6 , pp. 369-372
    • Xu, Y.Y.1    Guo, H.R.2    Qin, X.3    Su, F.4    Yin, L.C.5
  • 44
    • 61549091966 scopus 로고    scopus 로고
    • In vitro acute cytotoxicity of neonicotinoid insecticide imidacloprid to gill cell line of flounder Paralichthy olivaceus
    • Su, F.; Zhang, S.C.; Li, H.Y.; Guo, H.R. In vitro acute cytotoxicity of neonicotinoid insecticide imidacloprid to gill cell line of flounder Paralichthy olivaceus. Chin. J. Oceanol. Limnol. 2007, 25, 209-214.
    • (2007) Chin. J. Oceanol. Limnol. , vol.25 , pp. 209-214
    • Su, F.1    Zhang, S.C.2    Li, H.Y.3    Guo, H.R.4
  • 45
    • 34247350720 scopus 로고    scopus 로고
    • Nonylphenol causes decrease in antioxidant enzyme activities, increase in O2- content, and alteration in ultrastructures of FG cells, a flounder (Paralichthy olivaceus) gill cell line
    • Xiao, Q.; Zhang, S.C.; Guo, H.R.; Su, F.; Xu, Y.Y. Nonylphenol causes decrease in antioxidant enzyme activities, increase in O2- content, and alteration in ultrastructures of FG cells, a flounder (Paralichthy olivaceus) gill cell line. Toxicol. Mech. Methods 2007, 17, 127-134.
    • (2007) Toxicol. Mech. Methods , vol.17 , pp. 127-134
    • Xiao, Q.1    Zhang, S.C.2    Guo, H.R.3    Su, F.4    Xu, Y.Y.5
  • 46
    • 0030781450 scopus 로고    scopus 로고
    • The establishment and partial characterization of a continuous fish cell line FG-9307 from the gill of flounder Paralichthys olivaceus
    • Tong, S.L.; Li, H.; Miao, H.Z. The establishment and partial characterization of a continuous fish cell line FG-9307 from the gill of flounder Paralichthys olivaceus. Aquaculture 1997, 156, 327-333.
    • (1997) Aquaculture , vol.156 , pp. 327-333
    • Tong, S.L.1    Li, H.2    Miao, H.Z.3
  • 47
    • 0018742394 scopus 로고
    • Unusual sensitivity of ataxia telangiectasia cells to bleomycin
    • Taylor, A.M.R.; Rosney, C.M.; Campbell, J.B. Unusual sensitivity of ataxia telangiectasia cells to bleomycin. Cancer Res. 1979, 39, 1046-1050.
    • (1979) Cancer Res , vol.39 , pp. 1046-1050
    • Taylor, A.M.R.1    Rosney, C.M.2    Campbell, J.B.3
  • 48
    • 0028204160 scopus 로고
    • DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways
    • Nelson, W.G.; Kastan, M.B. DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell Biol. 1994, 14, 1815-1823.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 1815-1823
    • Nelson, W.G.1    Kastan, M.B.2
  • 50
    • 40349108452 scopus 로고    scopus 로고
    • Mouse embryo fibroblast (MEF) feeder cell preparation
    • doi: 10.1002/0471142727
    • Conner, D.A. Mouse embryo fibroblast (MEF) feeder cell preparation. Curr. Protoc. Mol. Biol. 2000, doi: 10.1002/0471142727.
    • Curr. Protoc. Mol. Biol. , vol.2000
    • Conner, D.A.1
  • 51
    • 49649113454 scopus 로고    scopus 로고
    • Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: A follow-up to an ECVAM workshop
    • Kirkland, D.; Kasper, P.; Müller, L.; Corvi, R.; Speit, G. Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: A follow-up to an ECVAM workshop. Mutat. Res. 2008, 653, 99-108.
    • (2008) Mutat. Res. , vol.653 , pp. 99-108
    • Kirkland, D.1    Kasper, P.2    Müller, L.3    Corvi, R.4    Speit, G.5
  • 52
    • 77950155012 scopus 로고    scopus 로고
    • GADD45a-GFP GreenScreen HC assay results for the ECVAM recommended lists of genotoxic and non-genotoxic chemicals for assessment of new genotoxicity tests
    • Birrell, L.; Cahill, P.; Hughesa, C.; Tatea, M.; Walmsley, R.M. GADD45a-GFP GreenScreen HC assay results for the ECVAM recommended lists of genotoxic and non-genotoxic chemicals for assessment of new genotoxicity tests. Mutat. Res. 2010, 695, 87-95.
    • (2010) Mutat. Res. , vol.695 , pp. 87-95
    • Birrell, L.1    Cahill, P.2    Hughesa, C.3    Tatea, M.4    Walmsley, R.M.5
  • 55
    • 0028842645 scopus 로고
    • Cellular responses to DNA damage: Cell-Cycle checkpoints, apoptosis and the roles of p53 and ATM
    • Enoch, T.; Norbury, C. Cellular responses to DNA damage: Cell-Cycle checkpoints, apoptosis and the roles of p53 and ATM. Trends Biochem. Sci. 1995, 20, 426-430.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 426-430
    • Enoch, T.1    Norbury, C.2
  • 56
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell response to p53
    • Vousden, K.H.; Lu, X. Live or let die: The cell response to p53. Nat. Rev. Cancer 2002, 2, 594-604.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 58
    • 0027109075 scopus 로고
    • Cancer. p53, guardian of the genome
    • Lane, D.P. Cancer. p53, guardian of the genome. Nature 1992, 358, 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 59
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A.J. p53, the cellular gatekeeper for growth and division. Cell 1997, 88, 323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 60
    • 0037253985 scopus 로고    scopus 로고
    • Spontaneous neoplastic transformation of the cell line FG-9307 from Olive flounder
    • Guo, H.R.; Zhang, S.C.; Li, H.Y. Spontaneous neoplastic transformation of the cell line FG-9307 from Olive flounder. N. Am. J. Aquac. 2003, 65, 44-48.
    • (2003) N. Am. J. Aquac. , vol.65 , pp. 44-48
    • Guo, H.R.1    Zhang, S.C.2    Li, H.Y.3
  • 61
    • 33846278350 scopus 로고    scopus 로고
    • A p53-like protein from a freshwater mollusc Lamellidens corrianus
    • Mohanty, B.P. A p53-like protein from a freshwater mollusc Lamellidens corrianus. Indian J. Biochem. Biophys. 2006, 43, 247-250.
    • (2006) Indian J. Biochem. Biophys. , vol.43 , pp. 247-250
    • Mohanty, B.P.1
  • 62
    • 0031172274 scopus 로고    scopus 로고
    • Characterization of gene expression of a p53 homologue in the soft-shell clam (Mya arenaria)
    • Van Beneden, R.J.; Walker, C.W.; Laughner, E.S. Characterization of gene expression of a p53 homologue in the soft-shell clam (Mya arenaria). Mol. Mar. Biol. Biotechnol. 1997, 6, 116-122.
    • (1997) Mol. Mar. Biol. Biotechnol. , vol.6 , pp. 116-122
    • Van Beneden, R.J.1    Walker, C.W.2    Laughner, E.S.3
  • 63
    • 0029028352 scopus 로고
    • Mutational analysis of the carboxy-terminal portion of p53 using both yeast and mammalian cell assays in vivo
    • Ishioka, C.; Englert, C.; Winge, P.; Yan, Y.X.; Engelstein, M.; Friend, S.H. Mutational analysis of the carboxy-terminal portion of p53 using both yeast and mammalian cell assays in vivo. Oncogene 1995, 10, 1485-1492.
    • (1995) Oncogene , vol.10 , pp. 1485-1492
    • Ishioka, C.1    Englert, C.2    Winge, P.3    Yan, Y.X.4    Engelstein, M.5    Friend, S.H.6
  • 65
    • 0023626862 scopus 로고
    • Cloning and characterization of a cDNA from Xenopus laevis coding for a protein homologous to human and murine p53
    • Soussi, T.; Caron de Fromentel, C.; Méchali, M.; May, P.; Kress, M. Cloning and characterization of a cDNA from Xenopus laevis coding for a protein homologous to human and murine p53. Oncogene 1987, 1, 71-78.
    • (1987) Oncogene , vol.1 , pp. 71-78
    • Soussi, T.1    Caron de Fromentel, C.2    Méchali, M.3    May, P.4    Kress, M.5
  • 67
    • 33646789152 scopus 로고    scopus 로고
    • Lessons from p53 in non-mammalian models
    • Lu, W.-J.; Abrams, J.M. Lessons from p53 in non-mammalian models. Cell Death Differ. 2006, 13, 909-912.
    • (2006) Cell Death Differ , vol.13 , pp. 909-912
    • Lu, W.-J.1    Abrams, J.M.2
  • 68
    • 0036898541 scopus 로고    scopus 로고
    • Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signalling
    • Langheinrich, U.; Hennen, E.; Stott, G.; Vacun, G. Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signalling. Curr. Biol. 2002, 12, 2023-2028.
    • (2002) Curr. Biol. , vol.12 , pp. 2023-2028
    • Langheinrich, U.1    Hennen, E.2    Stott, G.3    Vacun, G.4
  • 69
    • 0029360580 scopus 로고
    • Small, fast and deadly (but very selective)
    • Tomasz, M. Mitomycin C: Small, fast and deadly (but very selective). Chem. Biol. 1995, 2, 575-579.
    • (1995) Chem. Biol. , vol.2 , pp. 575-579
    • Tomasz, M.1    Mitomycin, C.2
  • 70
    • 0000357885 scopus 로고    scopus 로고
    • Nucleic acid recognition by metal complexes of bleomycin
    • Claussen, C.A.; Long, E.C. Nucleic acid recognition by metal complexes of bleomycin. Chem. Rev. 1999, 99, 2797-2816.
    • (1999) Chem. Rev. , vol.99 , pp. 2797-2816
    • Claussen, C.A.1    Long, E.C.2
  • 71
    • 34250617024 scopus 로고    scopus 로고
    • Alcohol, neurotransmitter systems, and behavior
    • Chastain, G. Alcohol, neurotransmitter systems, and behavior. J. Gen. Psychol. 2006, 133, 329-335.
    • (2006) J. Gen. Psychol. , vol.133 , pp. 329-335
    • Chastain, G.1
  • 72
    • 0014836063 scopus 로고
    • Enzymatic basis of cyclophosphamide activation by hepatic microsomes of the rat
    • Cohen, J.L.; Jao, J.Y. Enzymatic basis of cyclophosphamide activation by hepatic microsomes of the rat. J. Pharmacol. Exp. Ther. 1970, 174, 206-210.
    • (1970) J. Pharmacol. Exp. Ther. , vol.174 , pp. 206-210
    • Cohen, J.L.1    Jao, J.Y.2
  • 73
    • 0029239792 scopus 로고
    • Residue levels of phthalate esters in water and sediment samples from the Klang River basin
    • Tan, G.H. Residue levels of phthalate esters in water and sediment samples from the Klang River basin. Bull. Environ. Contam. Toxicol. 1995, 54, 171-176.
    • (1995) Bull. Environ. Contam. Toxicol. , vol.54 , pp. 171-176
    • Tan, G.H.1
  • 74
    • 84865622415 scopus 로고    scopus 로고
    • Genotoxicity and Potential Carcinogenic Mechanisms-A Review Available online (accessed on 27 July)
    • Caldwell, J.C. DEHP: Genotoxicity and Potential Carcinogenic Mechanisms-A Review. Available online: http://dx.doi.org/10.1016/j.mrrev.2012.03.001 (accessed on 27 July 2012).
    • (2012) DEHP
    • Caldwell, J.C.1


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