An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC) - Including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds

Mutagenesis

Volumn 22, Issue 6, 2007, Pages 409-416

  Knight, Andrew W ^a   Billinton, N ^a   Cahill, P A ^a   Scott, A ^b   Harvey, J S ^c   Roberts, K J ^c,e   Tweats, D J ^d   Keenan, P O ^a,f   Walmsley, R M ^a  

^a Gentronix Ltd   (United Kingdom)

^b UNILEVER RESEARCH   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d SWANSEA UNIVERSITY   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f LANCASTER UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; GREEN FLUORESCENT PROTEIN; RAD54 PROTEIN;

AMES TEST; ANIMAL CELL; ARTICLE; AUTOFLUORESCENCE; CARCINOGENICITY; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; CYTOTOXICITY; FALSE POSITIVE RESULT; GENOTOXICITY; GREENSCREEN MICROPLATE ASSAY; MAMMAL CELL; MOUSE; MUTAGEN TESTING; NONHUMAN; PRIORITY JOURNAL; RAT; REPRODUCIBILITY; RODENT; TOXICITY TESTING;

ANIMALS; CARCINOGENS; COLORING AGENTS; COMET ASSAY; DNA DAMAGE; FLUORESCENCE; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; LIVER; MUTAGENICITY TESTS; PROMOTER REGIONS (GENETICS); RATS; REPRODUCIBILITY OF RESULTS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SENSITIVITY AND SPECIFICITY;

MAMMALIA; RODENTIA;

EID: 36049046631     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gem036     Document Type: Article

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