Biofortified cassava increases β-carotene and vitamin A concentrations in the TAG-rich plasma layer of American women

British Journal of Nutrition

Volumn 110, Issue 2, 2013, Pages 310-320

  La Frano, Michael R ^a,b   Woodhouse, Leslie R ^a   Burnett, Dustin J ^a   Burri, Betty J ^a,b  

^a U S DEPARTMENT OF AGRICULTURE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Carotene; Biofortified cassava; Human studies; Vitamin A

Indexed keywords

ALPHA CAROTENE; BETA CAROTENE; LIPOPROTEIN; RETINOL; RETINOL PALMITATE;

ABSORPTION; ADULT; ARTICLE; BIOEQUIVALENCE; BIOTRANSFORMATION; BODY MASS; CASSAVA; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DIETARY INTAKE; FEMALE; FOOD INTAKE; FOOD PROCESSING; GLUCOSE BLOOD LEVEL; HEMATOCRIT; HUMAN; HUMAN EXPERIMENT; KIDNEY FUNCTION TEST; LIPOPROTEIN BLOOD LEVEL; LIVER FUNCTION TEST; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; SAPONIFICATION; VITAMIN BLOOD LEVEL;

ADULT; AREA UNDER CURVE; BETA CAROTENE; FEMALE; FOOD, FORTIFIED; HUMANS; LIPOPROTEINS; MANIHOT; PLANT OILS; REFERENCE VALUES; TRIGLYCERIDES; VITAMIN A; VITAMIN A DEFICIENCY; YOUNG ADULT;

ARACHIS HYPOGAEA; BRASSICA NAPUS; MANIHOT ESCULENTA;

EID: 84879189405     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114512005004     Document Type: Article

References (56)

1. Black RE, Allen LH, Bhutta ZA, et al. (2008) Maternal and child undernutrition: global and regional exposures and health consequences. Lancet 371, 243-260.
2. Sayre R, Beeching JR, Cahoon EB, et al. (2011) The biocassava plus program: biofortification of cassava for sub-saharan Africa. Annu Rev Plant Biol 62, 251-272.
3. Montagnac JA, Davis CR & Tanumihardjo SA (2009) Nutritional value of cassava for use as a staple food and recent advances for improvement. Compr Rev Food Sci Food Saf 8, 181-194.
4. Gegios A, Amthor R, Maziya-Dixon B, et al. (2010) Children consuming cassava as a staple food are at risk for inadequate zinc, iron, and vitamin A intake. Plant Food Hum Nutr 65, 64-70.
5. Nhassico D, Mubquingue H, Cliff J, et al. (2008) Rising African cassava production, diseases due to high cyanide intake and control measures. J Sci Food Agric 88, 2043-2049.
6. Bouis HE, Hotz C, McClafferty B, et al. (2011) Biofortification: a new tool to reduce micronutrient malnutrition. Food Nutr Bull 32, S31-S40.
7. Pfeiffer WH & McClafferty B (2008) HarvestPlus: breeding crops for better nutrition. Crop Sci 47, S88-S105.
8. Bradbury JH & Denton IC (2011) Mild methods of processing cassava leaves to remove cyanogens and conserve key nutrients. Food Chem 127, 1755-1759.
9. Chavez AL, Sanchez T, Ceballos H, et al. (2007) Retention of carotenoids in cassava roots submitted to different processing methods. J Sci Food Agric 87, 388-393.
10. Vimala B, Thushara R, Nambisan B, et al. (2011) Effect of processing on the retention of carotenoids in yellow-fleshed cassava (Manihot esculenta Crantz) roots. Int J Food Sci Technol 46, 166-169.
11. Yeum KJ & Russell RM (2002) Carotenoid bioavailability and bioconversion. Annu Rev Nutr 22, 483-504.
12. Howe JA, Maziya-Dixon B & Tanumihardjo SA (2009) Cassava with enhanced b-carotene maintains adequate vitamin A status in Mongolian gerbils (Meriones unguiculatus) despite substantial cis-isomer content. Br J Nutr 102, 342-349.
13. van Vliet T, Schreurs WHP & van den Berg H (1995) Intestinal b-carotene absorption and cleavage in men: response of b-carotene and retinyl esters in the triglyceride-rich lipoprotein fraction after a single oral dose of b-carotene. Am J Clin Nutr 62, 110-116.
14. ESA (2008) Application note. Simultaneous analysis of carotenoids, retinoids, tocopherols, vitamin K1 and coenzyme Q10 in plasma. http://www.esainc.com/download/?id204 (accessed December 2010).
15. Berr F & Kern F (1984) Plasma clearance of chylomicrons labeled with retinyl palmitate in healthy human subjects. J Lipid Res 25, 805-812.
16. Li S, Nugroho A, Rocheford T, et al. (2010) Vitamin A equivalence of the b-carotene in b-carotene-biofortified maize porridge consumed by women. Am J Clin Nutr 92, 1105-1112.
17. Sivakumar B & Reddy V (1972) Absorption of labelled vitamin A in children during infection. Br J Nutr 27, 299-304.
18. Biesalski HK (1997) Bioavailability of vitamin A. Eur J Clin Nutr 51, S71-S75.
19. O'Neill ME & Thurnham DI (1998) Intestinal absorption of b-carotene, lycopene and lutein in men and women following a standard meal: response curves in the triacylglycerolrich lipoprotein fraction. Br J Nutr 79, 149-159.
20. Cortner JA, Coates PM, Le NA, et al. (1987) Kinetics of chylomicron remnant clearance in normal and in hyperlipoproteinemic subjects. J Lipid Res 28, 195-206.
21. Goodman DWS, Blomstrand R, Werner B, et al. (1966) Intestinal absorption and metabolism of vitamin A and b-carotene in man. J Clin Invest 45, 1615-1623.
22. Grundy SM & Mok HYI (1976) Chylomicron clearance in normal and hyperlipidemic man. Metabolism 25, 1225-1239.
23. Harrison EH (2012) Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoids. Biochim Biophys Acta 1821, 70-77.
24. Boer P (1984) Estimated lean body mass as an index for normalization of body fluid volumes in humans. Am J Physiol 247, F632-F636.
25. Tang G, Qin J, Dolnikowski GG, et al. (2005) Spinach or carrots can supply significant amounts of vitamin A as assessed by feeding with intrinsically deuterated vegetables. Am J Clin Nutr 82, 821-828.
26. Berr F, Eckel R & Kern F (1985) Plasma decay of chylomicron remnants is not affected by heparin-stimulated plasma lipolytic activity in normal fasting man. J Lipid Res 26, 852-859.
27. Berr F, Eckel RH & Kern F (1986) Contraceptive steroids increase hepatic uptake of chylomicron remnants in healthy young women. J Lipid Res 27, 645-651.
28. Hu X, Jandacek RJ & White WS (2000) Intestinal absorption of b-carotene ingested with a meal rich in sunflower oil or beef tallow: postprandial appearance in triacylglycerol-rich lipoproteins in women. Am J Clin Nutr 71, 1170-1180.
29. Johnson EJ & Russell RM (1992) Distribution of orally administered b-carotene among lipoproteins in healthy men. Am J Clin Nutr 56, 128-135.
30. Brown MJ, Ferruzzi MG, Nguyen ML, et al. (2004) Carotenoid bioavailability is higher from salads ingested with full-fat than with fat-reduced salad dressings as measured with electrochemical detection. Am J Clin Nutr 80, 396-403.
31. Paetau I, Chen H, Goh NM, et al. (1997) Interactions in the postprandial appearance of b-carotene and canthaxanthin in plasma triacylglycerol-rich lipoproteins in humans. Am J Clin Nutr 66, 1133-1143.
32. Jalal F, Nesheim MC, Agus Z, et al. (1998) Serum retinol concentrations in children are affected by food sources of b-carotene, fat intake, and anthelmintic drug treatment. Am J Clin Nutr 68, 623-629.
33. Jayarajan P, Reddy V & Mohanram M (1980) Effect of dietaryfat on absorption of beta-carotene from green leafy vegetables in children. Indian J Med Res 71, 53-56.
34. Roodenburg AJC, Leenen R, van het Hof KH, et al. (2000) Amount of fat in the diet affects bioavailability of lutein esters but not of a-carotene, b-carotene, and vitamin E in humans. Am J Clin Nutr 71, 1187-1193.
35. Dmitrov NV, Meyer C, Ullrey DE, et al. (1988) Bioavailability of b-carotene in humans. Am J Clin Nutr 48, 298-304.
36. Cardinault N, Tyssandier V, Grolier P, et al. (2003) Comparison of the postprandial chylomicron carotenoid responses in young and older subjects. Eur J Nutr 42, 315-323.
37. Tyssandier V, Cardinault N, Caris-Veyrat C, et al. (2002) Vegetable-borne lutein, lycopene, and beta-carotene compete for incorporation into chylomicrons, with no adverse effect on the medium-term (3-wk) plasma status of carotenoids in human. Am J Clin Nutr 75, 526-534.
38. van den Berg H & van Vliet T (1998) Effect of simultaneous, single oral doses of b-carotene with lutein or lycopene on the b-carotene and retinyl ester responses in the triacylglycerol-rich lipoprotein fraction of men. Am J Clin Nutr 68, 82-89.
39. Khachik F, Beecher GR, Goli MB, et al. (1991) Separation, identification, and quantification of carotenoids in fruits, vegetables and human plasma by high performance liquid chromatography. Pure Appl Chem 63, 71-80.
40. Dietz JM, Kantha SS & Erdman JW (1988) Reversed phase HPLC analysis of alpha-carotene and beta-carotene from selected raw and cooked vegetables. Plant Foods Hum Nutr 38, 333-341.
41. Borel P, Grolier P, Mekki N, et al. (1998) Low and high responders to pharmacological doses of b-carotene: proportion in the population, mechanisms involved and consequences on b-carotene metabolism. J Lipid Res 39, 2250-2260.
42. Hickenbottom SJ, Follet JR, Lin Y, et al. (2002) Variability in conversion of b-carotene to vitamin A in men as measured by using a double-tracer study design. Am J Clin Nutr 75, 900-907.
43. Lin Y, Dueker SR, Burri BJ, et al. (2000) Variability of the conversion of b-carotene to vitamin A in women measured by using a double-tracer study design. Am J Clin Nutr 71, 1545-1554.
44. von Lintig J (2010) Colors with functions: elucidating the biochemical and molecular basis of carotenoid metabolism. Annu Rev Nutr 30, 35-56.
45. Muzhingi T, Gadaga TH, Siwela AH, et al. (2011) Yellow maize with high b-carotene is an effective source of vitamin A in healthy Zimbabwean men. Am J Clin Nutr 94, 510-519.
46. Lee CM, Boileau AC, Boileau TW, et al. (1999) Review of animal models in carotenoid research. J Nutr 129, 2271-2277.
47. Tanumihardjo SA, Palacios N & Pixley KV (2010) Provitamin A carotenoid bioavailability: what really matters? Int J Vitam Nutr Res 80, 336-350.
48. Tang G, Qin J, Dolnikowski GG, et al. (2009) Golden rice is an effective source of vitamin A. Am J Clin Nutr 89, 1776-1783.
49. de Pee S, West CE, Permaesih D, et al. (1998) Orange fruit is more effective than are dark-green, leafy vegetables in increasing serum concentrations of retinol and b-carotene in schoolchildren in Indonesia. Am J Clin Nutr 68, 1058-1067.
50. Haskell MJ, Jamil KM, Hassan F, et al. (2004) Daily consumption of Indian spinach (Basella alba) or sweet potatoes has a positive effect on total-body vitamin A stores in Bangladeshi men. Am J Clin Nutr 80, 705-714.
51. Khan NC, West CE, de Pee S, et al. (2007) The contribution of plant foods to the vitamin A supply of lactating women in Vietnam: a randomized controlled trial. Am J Clin Nutr 85, 1112-1120.
52. Tang G, Gu XF, Hu SM, et al. (1999) Green and yellow vegetables can maintain body stores of vitamin A in Chinese children. Am J Clin Nutr 70, 1069-1076.
53. Tang G (2010) Bioconversion of dietary provitamin A carotenoids to vitamin A in humans. Am J Clin Nutr 91, S1468-S1473.
54. Iglesias C, Mayer J, Chavez L, et al. (1997) Genetic potential and stability of carotene content in cassava roots. Euphytica 94, 367-373.
55. Montagnac JA, Davis CR & Tanumihardjo SA (2009) Processing techniques to reduce toxicity and antinutrients of cassava for use as a staple food. Compr Rev Food Sci Food Saf 8, 17-27.
56. Ubalua AO (2010) Cyanogenic glycosides and the fate of cyanide in soil. Aust J Crop Sci 4, 223-237.