Amount of fat in the diet affects bioavailability of lutein esters but not of α-carotene, β-carotene, and vitamin E in humans

American Journal of Clinical Nutrition

Volumn 71, Issue 5, 2000, Pages 1187-1193

  Roodenburg, Annet J C ^a   Leenen, Rianne ^a   Van Het Hof, Karin H ^a   Weststrate, Jan A ^a   Tijburg, Lilian B M ^a  

^a UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

Author keywords

Absorption; Bioavailability; Carotenoids; Dietary fat; Lutein; Netherlands; Vitamin E; carotene; tocopherol; carotene

Indexed keywords

ALPHA CAROTENE; ALPHA TOCOPHEROL; BETA CAROTENE; ESTER DERIVATIVE; XANTHOPHYLL;

ADULT; AGED; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DIET SUPPLEMENTATION; FEMALE; FOOD COMPOSITION; HUMAN; HUMAN EXPERIMENT; LIPID ABSORPTION; LIPID BLOOD LEVEL; LIPID DIET; MALE; NORMAL HUMAN; VITAMIN BLOOD LEVEL;

EID: 0034014433     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/71.5.1187     Document Type: Article

References (39)

1. Rimm EB, Stampfer MJ, Ascherio A, Giovannucci E, Colditz GA, Willett WC. Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med 1993;328:1450-6.
2. Stampfer MJ, Hennekens CH, Manson JE, Colditz GA, Rosner B, Willett WC. Vitamin E consumption and the risk of coronary disease in women. N Engl J Med 1993;328:1444-9.
3. Gey KF. Ten-year retrospective on the antioxidant hypothesis of arteriosclerosis: threshold plasma levels of antioxidant micronutrients related to minimum cardiovascular risk. J Nutr Biochem 1995;6:206-36.
4. van Poppel G, Goldbohm RA. Epidemiologic evidence for β-carotene and cancer prevention. Am J Clin Nutr 1995;62(suppl):1393S-402S.
5. Willett WC, Trichopoulos D. Nutrition and cancer: a summary of the evidence. Cancer Causes Control 1996;7:178-80.
6. Heinonen OP, Albanes D, Virtamo, et al. Prostate cancer and supplementation with α-tocopherol and β-carotene: incidence and mortality in a controlled trial. J Natl Cancer Inst 1998;90:440-6.
7. Sies H, Stahl W. Vitamins E and C, β-carotene, and other carotenoids as antioxidants. Am J Clin Nutr 1995;62(suppl):1315S-21S.
8. Federation of American Societies for Experimental Biology (FASEB). Life Sciences Research Office. Third report on nutrition monitoring in the United States: vol 2. Washington, DC: US Government Printing Office, 1995.
9. Eitenmiller RR. Vitamin E content of fats and oils - nutritional implications. Food Technol 1997;51:78-81.
10. Chug-Ahuja JK, Holden JM, Forman MR, Mangels AR, Beecher GR, Lanza E. The development and application of a carotenoid database for fruits, vegetables, and selected multicomponent foods. J Am Diet Assoc 1993;93:318-23.
11. Mangels AR, Holden JM, Beecher GR, Forman MR, Lanza E. Carotenoid content of fruits and vegetables: an evaluation of analytic data. J Am Diet Assoc 1993;93:284-96.
12. Kayden HJ, Traber MG. Absorption, lipoprotein transport, and regulation of plasma concentrations of vitamin E in humans. J Lipid Res 1993;34:343-58.
13. Parker RS. Absorption, metabolism and transport of carotenoids. FASEB J 1996;10:542-51.
14. Conn W. Bioavailability of vitamin E. Eur J Clin Nutr 1997:51:S80-5.
15. Dimitrov NV, Meyer C, Gilliland D, Ruppenthal M, Chenoweth W, Malone W. Plasma tocopherol concentrations in response to supplemental vitamin E. Am J Clin Nutr 1991;53:723-9.
16. Brink EJ, Haddeman E, Tijburg LBM. Vitamin E incorporated into a very-low-fat meal is absorbed from the intestine of young rats. Br J Nutr 1996;75:939-48.
17. Tijburg LBM, Haddeman E, Kivits GAA, Weststrate JA, Brink EJ. Dietary linoleic acid at high and reduced dietary fat level decreases the faecel excretion of vitamin E in young rats. Br J Nutr 1997; 77:327-36.
18. Gallo-Torres HE, Weber F, Wiss O. The effect of dietary lipids on the lymphatic appearance of vitamin E. Int J Vitam Nutr Res 1971;41:504-15.
19. Jayarajan P, Reddy V, Mohanram M. Effect of dietary fat on absorption of β-carotene from green leafy vegetables in children. Indian J Med Res 1980;71:53-6.
20. Dimitrov NV, Meyer C, Ullrey DE, et al. Bioavailability of β-carotene in humans. Am J Clin Nutr 1988;48:298-304.
21. Prince MR, Frisoli JK. Beta-carotene accumulation in serum and skin. Am J Clin Nutr 1993;57:175-81.
22. Shiau A, Mobarhan S, Stacewicz-Sapuntzakis M, et al. Assessment of the intestinal retention of β-carotene in humans. J Am Coll Nutr 1994;13:369-75.
23. Jalal F, Nesheim MC, Agus Z, Sanjur D, Habicht JP. Serum retinol concentrations in children are affected by food sources of β-carotene, fat intake, and anthelmintic drug treatment. Am J Clin Nutr 1998;68:623-9.
24. Dutch Nutrition Information Centre. The Netherlands eats, 1992. Results of the dietary intake survey 1992. The Hague, Netherlands: Dutch Nutrition Information Centre, 1992.
25. Van Amelsvoort JMM, Stratum P, Kraal JH, Lussenburg RN, Houtsmuller UMT. Effects of varying the carbohydrate:fat ratio in a hot lunch on postprandial variables in male volunteers. Br J Nutr 1989;61:267-83.
26. National Research Council. Recommended dietary allowances. 10th ed. Washington, DC: National Academy Press, 1989.
27. Dutch Nutrition Council. Dutch recommended dietary intake of nutrients 1989. The Hague, Netherlands: Dutch Nutrition Information Centre, 1989.
28. Goldbohm RA, Brants HAM, Hulshof KFAM, Van den Brandt PA. The contribution of various foods to intake of vitamin A and carotenoids in the Netherlands. Int J Vitam Nutr Res 1998;68: 378-83.
29. Traber MG, Diamond SR, Lane JC, Brody RI, Kayden HJ. β-Carotene transport in human lipoproteins. Comparisons with α-tocopherol. Lipids 1994;29:665-9.
30. During A, Nagao A, Terao J. β-Carotene 15.15′-dioxygenase activity and cellular retinol-binding protein type II are enhanced by dietary unsaturated triacylglycerols in rat intestines. J Nutr 1998; 128:1614-9.
31. Granado F, Olmedilla B, Gil-Martinez E, Blanco I. Lutein ester in serum after lutein supplementation in human subjects. Br J Nutr 1998;80:445-9.
32. Straub O. Key to carotenoids. 2nd ed. Basel, Switzerland: Birkhäuser Verlag, 1987.
33. Tso P. Intestinal lipid absorption. In: Johnson LR, ed. Physiology of the gastrointestinal tract. 3rd ed. New York: Raven Press, 1994: 1867-900.
34. Wingerath T, Stahl W. Sies H. β-Cryptoxanthin selectively increases in human chylomicrons upon ingestion of tangerine concentrate rich in β-cryptoxanthin esters. Arch Biochem Biophys 1995;324: 385-90.
35. Herbst S, Bowen PE, Hussain E, Stacewics-Sapuntzakis M, Damayanti B, Burns J. Evaluation of the bioavailability of lutein and lutein diesters in humans. FASEB J 1997;11:2587 (abstr).
36. Khachik F, Beecher GR, Goli MB. Separation, identification, and quantification of carotenoids in fruits, vegetables and human plasma by high performance liquid chromatography. Pure Appl Chem 1991;63:71-80.
37. Castenmiller JJM, West CE, Linssen JPH, van het Hof KH, Voragen AGJ. Food matrix of spinach is a limiting factor in determining the bioavailability of beta-carotene but to a lesser extent of lutein. J Nutr 1999;129:349-55.
38. van het Hof KH, Brouwer IA, West CE, et al. Bioavailability of lutein from vegetables is 5 times higher than that of β-carotene. Am J Clin Nutr 1999;70:261-8.
39. van het Hof KH, Tijburg LBM, De Boer HSM, Wiseman SA, West-strate JA. Antioxidant fortified margarine increases the antioxidant status. Eur J Clin Nutr 1998;52:292-9.