Carotenoid bioavailability is higher from salads ingested with full-fat than with fat-reduced salad dressings as measured with electrochemical detection

American Journal of Clinical Nutrition

Volumn 80, Issue 2, 2004, Pages 396-403

  Brown, Melody J ^a   Ferruzzi, Mario G ^b   Nguyen, Minhthy L ^b   Cooper, Dale A ^c   Eldridge, Alison L ^c   Schwartz, Steven J ^b   White, Wendy S ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

Bioavailability; Carotenoids; Chylomicrons; Coulometric array; Electrochemical detection; Fat; Fat reduced salad dressings; Intestinal absorption; Lycopene; Salad; Salad dressing; Vegetables; Carotene; carotene

Indexed keywords

ALPHA CAROTENE; BETA CAROTENE; CAROTENOID; CHYLOMICRON; FAT; LYCOPENE; OIL; ANTIOXIDANT; CANOLA OIL; MONOUNSATURATED FATTY ACID;

ABSORPTION; ARTICLE; BLOOD SAMPLING; CARROT; COMPARATIVE STUDY; CONTROLLED STUDY; COULOMETRY; ELECTROCHEMISTRY; FAT INTAKE; FOOD INTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INGESTION; LETTUCE; NORMAL HUMAN; PLASMA; QUANTITATIVE ANALYSIS; RANDOMIZATION; RAPESEED; SPINACH; TIME; TOMATO; ULTRACENTRIFUGATION; VEGETABLE; ADULT; BIOAVAILABILITY; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG EFFECT; FEMALE; FOOD ANALYSIS; INTESTINE ABSORPTION; MALE; METABOLISM; RANDOMIZED CONTROLLED TRIAL;

BRASSICA NAPUS VAR. NAPUS; DAUCUS CAROTA; LACTUCA; LYCOPERSICON ESCULENTUM VAR. CERASIFORME; SPINACIA OLERACEA;

ADULT; ANTIOXIDANTS; BIOLOGICAL AVAILABILITY; CAROTENOIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHYLOMICRONS; FATTY ACIDS, MONOUNSATURATED; FEMALE; FOOD ANALYSIS; HUMANS; INTESTINAL ABSORPTION; MALE; VEGETABLES;

EID: 4344675542     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/80.2.396     Document Type: Article

References (50)

1. Stahl W, van den Berg H, Arthur J, et al. Bioavailability and metabolism. Mol Aspects Med 2002;23:39-100.
2. Tyssandier V, Reboul E, Dumas J-F, et al. Processing of vegetable-borne carotenoids in the human stomach and duodenum. Am J Physiol Gastrointest Liver Physiol 2003;284:G913-23.
3. Hedrén E, Diaz V, Svanberg U. Estimation of carotenoid accessibility from carrots determined by an in vitro digestion method. Eur J Clin Nutr 2002;56:425-30.
4. Gärtner C, Stahl W, Sies H. Lycopene is more bioavailable from tomato paste than from fresh tomatoes. Am J Clin Nutr 1997;66:116-22.
5. Rock CL, Lovalvo JL, Emenhiser C, Ruffin MT, Flatt SW, Schwartz SJ. Bioavailability of β-carotene is lower in raw than in processed carrots and spinach in women. J Nutr 1998;128:913-6.
6. van het Hof KH, de Boer BCJ, Tijburg LBM, et al. Carotenoid bioavailability in humans from tomatoes processed in different ways determined from the carotenoid response in the triglyceride-rich lipoprotein fraction of plasma after a single consumption and in plasma after four days of consumption. J Nutr 2000;130:1189-96.
7. Dimitrov NV, Meyer C, Ullrey DE,et al. Bioavailability of β-carotene in humans. Am J Clin Nutr 1988;48:298-04.
8. Prince MR, Frisoli JK. Beta-carotene accumulation in serum and skin. Am J Clin Nutr 1993;57:175-81.
9. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids (macronutrients). Washington, DC: National Academy Press, 2002.
10. Keenan DP, Achterberg C, Kris-Etherton PM, Abusabha R, Von Eye A. Use of qualitative and quantitative methods to define behavioral fat-reduction strategies and their relationship to dietary fat reduction in the Patterns of Dietary Change Study. J Am Diet Assoc 1996;96:1245-50.
11. Kennedy E, Bowman S. Assessment of the effect of fat-modified foods on diet quality in adults, 19 to 50 years, using data from the Continuing Survey of Food Intake by Individuals. J Am Diet Assoc 2001;101:455-60.
12. Krebs-Smith SM, Cronin FJ, Haytowitz DB, Cook DA. Food sources of energy, macronutrients, cholesterol, and fiber in diets of women. J Am Diet Assoc 1992;92:168-74.
13. Sandrou DK, Arvanitoyannis IS. Low-fat/calorie foods: current state and perspectives. Crit Rev Food Sci Nutr 2000;40:427-47.
14. Capps O, Cleveland L, Park J. Dietary behaviors associated with total fat and saturated fat intake. J Am Diet Assoc 2002;102:490-502.
15. D'Odorico A, Martines D, Kiechl S, et al. High plasma levels of α- and β-carotene are associated with a lower risk of atherosclerosis: results from the Bruneck study. Atherosclerosis 2000;153:231-9.
16. Rissanen TH, Voutilainen S, Nyyssönen K, et al. Low serum lycopene concentration is associated with an excess incidence of acute coronary events and stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study. Br J Nutr 2001;85:749-54.
17. Michaud DS, Feskanich D, Rimm EB, et al. Intake of specific carotenoids and risk of lung cancer in 2 prospective US cohorts. Am J Clin Nutr 2000;72:990-7.
18. Gale CR, Hall NF, Phillips DI, Martyn CN. Lutein and zeaxanthin status and risk of age-related macular degeneration. Invest Ophthalmol Vis Sci 2003;44:2461-5.
19. Ferruzzi MG, Sander LC, Rock CL, Schwartz SJ. Carotenoid determination in biological microsamples using liquid chromatography with a coulometric electrochemical array detector. Anal Biochem 1998;256:74-81.
20. White WS, Stacewicz-Sapuntzakis M, Erdman JW, Bowen PE. Pharmacokinetics of β-carotene and canthaxanthin after ingestion of individual and combined doses by human subjects. J Am Coll Nutr 1994;13:665-71.
21. US Department of Agriculture, Agricultural Research Service. Results from USDA's 1994-1996 Continuing Survey of Food Intakes by Individuals and 1994-96 Diet and Health Knowledge Survey, table set 10, table 4. In: 1994-96 Continuing Survey of Food Intakes by Individuals and 1994-96 Diet and Health Knowledge Survey. (CD-ROM). (NTIS accession no. PB98-500457.)
22. Rabbani S, Beyer P, von Lintig J, Hugueney P, Kleinig H. Induced β-carotene synthesis driven by triacylglycerol deposition in the unicellular alga Dunaliella bardawil. Plant Physiol 1998;116:1239-48.
23. AOAC International. Official methods of analysis. 16th ed. Vol 1. Gaithersburg, MD: AOAC International, 1995:945.02.
24. van Vliet T, Schreurs WHP, van den Berg H. Intestinal β-carotene absorption and cleavage in men: response of β-carotene and retinyl esters in the triglyceride-rich lipoprotein fraction after a single oral dose of β-carotene. Am J Clin Nutr 1995;62:110-6.
25. Redgrave TG, Carlson LA. Changes in plasma very low density and low density lipoprotein content, composition, and size after a fatty meal in normo- and hypertriglyceridemic man. J Lipid Res 1979;20:217-29.
26. Lindgren FT. Preparative ultracentrifugal laboratory procedures and suggestions for lipoprotein analysis. In: Perkins EG, ed. Analysis of lipids and lipoproteins. Champaign, IL: American Oil Chemists' Society, 1975:204-24.
27. Hu X, Jandacek RJ, White WS. Intestinal absorption of β-carotene ingested with a meal rich in sunflower oil or beef tallow: postprandial appearance in triacylglycerol-rich lipoproteins in women. Am J Clin Nutr 2000;71:1170-80.
28. Paetau I, Chen H, Goh NM, White WS. Interactions in the postprandial appearance of β-carotene and canthaxanthin in plasma triacylglycerol-rich lipoproteins in humans. Am J Clin Nutr 1997;66:1133-43.
29. Hart DJ, Scott KJ. Development and evaluation of an HPLC method for the analysis of carotenoids in foods, and the measurement of the carotenoid content of vegetables and fruits commonly consumed in the UK. Food Chem 1995;54:101-11.
30. Lessin WJ, Catigani GL, Schwartz SJ. Quantification of cis-trans isomers of provitamin A carotenoids in fresh and processed fruits and vegetables. J Agric Food Chem 1997;45:3728-32.
31. The USDA-NCC carotenoid database for U.S. foods. 1998. Version current 20 August 1998. Internet: http://www.nal.usda.gov/fnic/foodcomp/Data/car98/car98. html (accessed 21 July 1999).
32. Demming-Adams B. Carotenoids and photoprotection in plants: a role for the xanthophyll zeaxanthin. Biochim Biophys Acta 1990;1020:1-24.
33. Brown ED, Micozzi MS, Craft NE, et al. Plasma carotenoids in normal men after a single ingestion of vegetables or purified β-carotene. Am J Clin Nutr 1989;49:1258-65.
34. van den Berg H, van Vliet T. Effect of simultaneous, single oral doses of β-carotene with lutein or lycopene on the β-carotene and retinyl ester responses in the triacylglycerol-rich lipoprotein fraction of men. Am J Clin Nutr 1998;68:82-9.
35. Edwards AJ, You C-S, Swanson JE, Parker RS. A novel extrinsic reference method for assessing the vitamin A value of plant foods. Am J Clin Nutr 2001;74:348-55.
36. Edwards AJ, Nguyen CH, You C-S, Swanson JE, Emenhiser C, Parker RS. α- and β-Carotene from a commercial carrot puree are more bioavailable to humans than from boiled-mashed carrots, as determined using an extrinsic stable isotope reference method. J Nutr 2002;132:159-67.
37. Roodenburg AJC, Leenen R, van het Hof KH, Weststrate JA, Tijberg LBM. Amount of fat in the diet affects bioavailability of lutein esters but not of α-carotene, β-carotene, and vitamin E in humans. Am J Clin Nutr 2000;71:1187-93.
38. Rock CL, Swendseid ME. Plasma β-carotene response in humans after meals supplemented with dietary pectin. Am J Clin Nutr 1992;55:96-9.
39. Lairon D. Soluble fibers and dietary lipids. In: Kritchevsky D, Bonfield C, eds. Dietary fiber in health and disease. New York: Plenum Press, 1997:99-108.
40. During A, Hussain MM, Morel DW, Harrison EH. Carotenoid uptake and secretion by CaCo-2 cells: beta-carotene isomer selectivity and carotenoid interactions. J Lipid Res 2002;43:1086-95.
41. van Lieshout M, West CE, Muhilal, et al. Bioefficacy of β-carotene dissolved in oil studied in children in Indonesia. Am J Clin Nutr 2001;73:949-58.
42. Hickenbottom SJ, Follett JR, Lin Y, et al. Variability in conversion of β-carotene to vitamin A in men as measured by using a double-tracer study design. Am J Clin Nutr 2002;75:900-7.
43. Jalal F, Nesheim MC, Agus Z, Sanjur D, Habicht JP. Serum retinol concentrations in children are affected by food sources of β-carotene, fat intake, and anthelmintic drug treatment. Am J Clin Nutr 1998;68:623-9.
44. Jayarajan P, Reddy V, Mohanram M. Effect of dietary fat on absorption of β-carotene from green leafy vegetables in children. Indian J Med Res 1980;71:53-6.
45. Takyi EEK. Children's consumption of dark green, leafy vegetables with added fat enhances serum retinol. J Nutr 1999;129:1549-54.
46. Alam DS, Yunus M, Aziz KMA,et al. Effects of dietary fat supplementation during pregnancy/lactation on maternal blood and breastmilk vitamin A in rural Bangladesh. FASEB J 1999;13:A895(abstr).
47. Nimsakul S, Ausayakun S, Kootathep S, et al. Effect of supplementary fat on vitamin A status of ethnic Karen children in northern Thailand. In: IVACG Secretariat, ed. Vitamin A and other micronutrients: biologic interactions and integrated interventions. Washington, DC: ILSI Research Foundation, 1999:88(abstr).
48. Nestel P, Nalubola R. As little as one teaspoon of dietary fat in a meal enhances the absorption of β-carotene. Washington, DC: ILSI, 2003.
49. US Department of Agriculture, US Department of Health and Human Services. Nutrition and your health: dietary guidelines for Americans. Internet: http://www.usda.gov/cnpp/DietGd.pdf (accessed 20 June 2001).
50. Djuric Z, Uhley VE, Naegeli L, Lababidi S, Macha S, Heilbrun LK. Plasma carotenoids, tocopherols, and antioxidant capacity in a 12-week intervention study to reduce fat and/or energy intakes. Nutrition 2003;19:244-9.