High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 14, 2012, Pages 5423-5428

  Fox, Jennifer T ^a   Sakamuru, Srilatha ^b   Huang, Ruili ^b   Teneva, Nedelina ^a   Simmons, Steven O ^c   Xia, Menghang ^b   Tice, Raymond R ^d   Austin, Christopher P ^b   Myung, Kyungjae ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Chemotherapy; High throughput screening

Indexed keywords

BAICALEIN; GENISTEIN; PROTEIN; PROTEIN ATAD5; RESVERATROL; UNCLASSIFIED DRUG;

AGING; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CARDIOVASCULAR DISEASE; CELL DEATH; CHRONIC HEPATITIS; CONTROLLED STUDY; DNA DAMAGE; GENOTOXICITY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; OSTEOPENIA; OSTEOPOROSIS; PRIORITY JOURNAL;

ANTIOXIDANTS; CELL DEATH; CELL LINE; DNA DAMAGE; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FLAVANONES; GENISTEIN; HUMANS; MUTAGENICITY TESTS; STILBENES;

EID: 84859464647     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1114278109     Document Type: Article

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