Nobiletin, a citrus flavonoid, ameliorates cognitive impairment, oxidative burden, and hyperphosphorylation of tau in senescence-accelerated mouse

Behavioural Brain Research

Volumn 250, Issue , 2013, Pages 351-360

  Nakajima, Akira ^a   Aoyama, Yuki ^a   Nguyen, Thuy Ty Lan ^b   Shin, Eun Joo ^b   Kim, Hyoung Chun ^b   Yamada, Shinnosuke ^a   Nakai, Tsuyoshi ^a   Nagai, Taku ^a   Yokosuka, Akihito ^c   Mimaki, Yoshihiro ^c   Ohizumi, Yasushi ^d,e,f   Yamada, Kiyofumi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Kangwon National University   (South Korea)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^d UNIVERSITY OF SHIZUOKA   (Japan)

^e YOKOHAMA COLLEGE OF PHARMACY   (Japan)

^f TOHOKU UNIVERSITY   (Japan)

Author keywords

Aging; Hyperphosphorylated tau; Memory; Nobiletin; Oxidative stress; SAM

Indexed keywords

CARBONYL DERIVATIVE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MANGANESE SUPEROXIDE DISMUTASE; NOBILETIN; TAU PROTEIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CEREBELLUM; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVITY; FEAR MEMORY; HIPPOCAMPUS; MALE; MEMORY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; RECOGNITION MEMORY; SENESCENCE ACCELERATED MOUSE;

AGING; ANALYSIS OF VARIANCE; ANIMALS; ANTIOXIDANTS; BODY WEIGHT; CASE-CONTROL STUDIES; COGNITION DISORDERS; CONDITIONING (PSYCHOLOGY); DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPLORATORY BEHAVIOR; FEAR; FLAVONES; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIPID METABOLISM; MALE; MAZE LEARNING; MICE; MICE, TRANSGENIC; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN CARBONYLATION; SUPEROXIDE DISMUTASE; TAU PROTEINS;

EID: 84879169263     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2013.05.025     Document Type: Article

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