Microsphere embolism-induced endothelial nitric oxide synthase expression mediates disruption of the blood-brain barrier in rat brain

Journal of Neurochemistry

Volumn 99, Issue 1, 2006, Pages 97-106

  Han, Feng ^a   Shirasaki, Yasufumi ^b   Fukunaga, Kohji ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

Blood brain barrier; Cerebral ischemia; Endothelial cells; Microsphere; Nitric oxide synthase; Tyrosine nitration

Indexed keywords

3 [2 [4 (3 CHLORO 2 METHYLPHENYL) 1 PIPERAZINYL]ETHYL] 5,6 DIMETHOXY 1 (4 IMIDAZOLYLMETHYL 1H INDAZOLE DIHYDROCHLORIDE 3.5 HYDRATE; BIOLOGICAL MARKER; CALMODULIN; DY 9760 E; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EVANS BLUE; IMMUNOGLOBULIN G; MICROSPHERE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXYNITRITE; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN EMBOLISM; BRAIN ISCHEMIA; CELL DISRUPTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; IMMUNOREACTIVITY; MALE; MEMBRANE DAMAGE; MICROSPHERE EMBOLISM; MICROVASCULATURE; NITRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; UPREGULATION; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; BRAIN ISCHEMIA; CALMODULIN; CEREBROVASCULAR CIRCULATION; EMBOLISM; ENDOTHELIUM, VASCULAR; ENZYME INDUCTION; IMMUNOHISTOCHEMISTRY; INDAZOLES; MICROSPHERES; NITRIC OXIDE SYNTHASE TYPE III; RATS;

ORYCTOLAGUS CUNICULUS;

EID: 33748699104     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04048.x     Document Type: Article

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