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Volumn 304, Issue 12, 2013, Pages

Identification of hypothalamic neuron-derived neurotrophic factor as a novel factor modulating appetite

Author keywords

Agouti related protein; Brain derived neurotrophic factor; Melanocortin; Neural circuitry; Whole body energy balance

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MELANOCORTIN; MESSENGER RNA; NEURON DERIVED NEUROTROPHIC FACTOR; RECOMBINANT BRAIN DERIVED NEUROTROPHIC FACTOR; UNCLASSIFIED DRUG;

EID: 84879165521     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00368.2012     Document Type: Article
Times cited : (35)

References (63)
  • 3
    • 72449134987 scopus 로고    scopus 로고
    • Allen Mouse Brain Atlas. Seattle, WA: Allen Institute for Brain Science
    • Allen Institute for Brain Science. Allen Mouse Brain Atlas. Seattle, WA: Allen Institute for Brain Science. http://mouse.brain-map.org, 2009.
    • (2009) Allen Institute for Brain Science
  • 4
    • 76949125582 scopus 로고
    • Hypothalamic control of food intake in rats and cats
    • Anand BK, Brobeck JR. Hypothalamic control of food intake in rats and cats. Yale J Biol Med 24: 124-140, 1951.
    • (1951) Yale J Biol Med , vol.24 , pp. 124-140
    • Anand, B.K.1    Brobeck, J.R.2
  • 6
    • 66649122305 scopus 로고    scopus 로고
    • BDNF/TrkB signaling is a downstream effector of the brainstem melano-cortin system in food intake control
    • Bariohay B, Roux J, Tardivel C, Trouslard J, Jean A, Lebrun B. BDNF/TrkB signaling is a downstream effector of the brainstem melano-cortin system in food intake control. Endocrinology 150: 2646-2653, 2009.
    • (2009) Endocrinology , vol.150 , pp. 2646-2653
    • Bariohay, B.1    Roux, J.2    Tardivel, C.3    Trouslard, J.4    Jean, A.5    Lebrun, B.6
  • 7
    • 84855500856 scopus 로고    scopus 로고
    • Metabolic and hedonic drives in the neural control of appetite: Who is the boss?
    • Berthoud HR. Metabolic and hedonic drives in the neural control of appetite: who is the boss? Curr Opin Neurobiol 21: 888-896, 2011.
    • (2011) Curr Opin Neurobiol , vol.21 , pp. 888-896
    • Berthoud, H.R.1
  • 9
    • 78149482636 scopus 로고    scopus 로고
    • Molecular pathways controlling development of thalamus and hypothalamus: From neural specification to circuit formation
    • Blackshaw S, Scholpp S, Placzek M, Ingraham H, Simerly R, Shi-mogori T. Molecular pathways controlling development of thalamus and hypothalamus: from neural specification to circuit formation. J Neurosci 30: 14925-14930, 2010.
    • (2010) J Neurosci , vol.30 , pp. 14925-14930
    • Blackshaw, S.1    Scholpp, S.2    Placzek, M.3    Ingraham, H.4    Simerly, R.5    Shi-Mogori, T.6
  • 10
    • 0030862358 scopus 로고    scopus 로고
    • Developmental expression pattern of phototransduction components in mammalian pineal implies a light-sensing function
    • Blackshaw S, Snyder SH. Developmental expression pattern of phototransduction components in mammalian pineal implies a light-sensing function. J Neurosci 17: 8074-8082, 1997.
    • (1997) J Neurosci , vol.17 , pp. 8074-8082
    • Blackshaw, S.1    Snyder, S.H.2
  • 12
    • 84875664465 scopus 로고    scopus 로고
    • Estrogen-related receptor beta deletion modulates whole-body energy balance via estrogen-related receptor gamma and attenuates neuropeptide Y gene expression
    • Byerly MS, Al Salayta M, Swanson RD, Kwon K, Peterson JM, Wei Z, Aja S, Moran TH, Blackshaw S, Wong GW. Estrogen-related receptor beta deletion modulates whole-body energy balance via estrogen-related receptor gamma and attenuates neuropeptide Y gene expression. EurJ Neurosci 37: 1033-1047, 2013.
    • (2013) EurJ Neurosci , vol.37 , pp. 1033-1047
    • Byerly, M.S.1    Al Salayta, M.2    Swanson, R.D.3    Kwon, K.4    Peterson, J.M.5    Wei, Z.6    Aja, S.7    Moran, T.H.8    Blackshaw, S.9    Wong, G.W.10
  • 17
    • 2442663015 scopus 로고    scopus 로고
    • A mechanism underlying mature-onset obesity: Evidence from the hyperphagic phenotype of brain-derived neurotrophic factor mutants
    • Fox EA, Byerly MS. A mechanism underlying mature-onset obesity: evidence from the hyperphagic phenotype of brain-derived neurotrophic factor mutants. Am J Physiol Regul Integr Comp Physiol 286: R994-R1004, 2004.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Fox, E.A.1    Byerly, M.S.2
  • 20
    • 0032400808 scopus 로고    scopus 로고
    • Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight
    • Grill HJ, Ginsberg AB, Seeley RJ, Kaplan JM. Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight. J Neurosci 18: 10128-10135, 1998.
    • (1998) J Neurosci , vol.18 , pp. 10128-10135
    • Grill, H.J.1    Ginsberg, A.B.2    Seeley, R.J.3    Kaplan, J.M.4
  • 21
    • 18044381195 scopus 로고    scopus 로고
    • Role of brain-derived neurotrophic factor in eating disorders: Recent findings and its pathophysiological implications
    • Hashimoto K, Koizumi H, Nakazato M, Shimizu E, Iyo M. Role of brain-derived neurotrophic factor in eating disorders: recent findings and its pathophysiological implications. Prog Neuropsychopharmacol Biol Psychiatry 29: 499-504, 2005.
    • (2005) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 499-504
    • Hashimoto, K.1    Koizumi, H.2    Nakazato, M.3    Shimizu, E.4    Iyo, M.5
  • 22
    • 85027474023 scopus 로고
    • Hypothalamic lesions and adiposity in the rat
    • Hetherington A, Ranson S. Hypothalamic lesions and adiposity in the rat. Anatom Record 78: 149-182, 1940.
    • (1940) Anatom Record , vol.78 , pp. 149-182
    • Hetherington, A.1    Ranson, S.2
  • 23
    • 0025279814 scopus 로고
    • Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain
    • Hofer M, Pagliusi SR, Hohn A, Leibrock J, Barde YA. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. EMBO J 9: 2459-2464, 1990.
    • (1990) EMBO J , vol.9 , pp. 2459-2464
    • Hofer, M.1    Pagliusi, S.R.2    Hohn, A.3    Leibrock, J.4    Barde, Y.A.5
  • 24
    • 0041488911 scopus 로고    scopus 로고
    • Trk receptors: Roles in neuronal signal transduction
    • Huang EJ, Reichardt LF. Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem 72: 609-642, 2003.
    • (2003) Annu Rev Biochem , vol.72 , pp. 609-642
    • Huang, E.J.1    Reichardt, L.F.2
  • 25
    • 0242353028 scopus 로고    scopus 로고
    • Altered levels of POMC, AgRP and MC4-R mRNA expression in the hypothalamus and other parts of the limbic system of mice prone or resistant to chronic high-energy diet-induced obesity
    • Huang XF, Han M, South T, Storlien L. Altered levels of POMC, AgRP and MC4-R mRNA expression in the hypothalamus and other parts of the limbic system of mice prone or resistant to chronic high-energy diet-induced obesity. Brain Res 992: 9-19, 2003.
    • (2003) Brain Res , vol.992 , pp. 9-19
    • Huang, X.F.1    Han, M.2    South, T.3    Storlien, L.4
  • 26
    • 67651174760 scopus 로고    scopus 로고
    • Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI
    • Kalnina I, Kapa I, Pirags V, Ignatovica V, Schioth HB, Klovins J. Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI. BMC Med Genet 10: 63, 2009.
    • (2009) BMC Med Genet , vol.10 , pp. 63
    • Kalnina, I.1    Kapa, I.2    Pirags, V.3    Ignatovica, V.4    Schioth, H.B.5    Klovins, J.6
  • 27
    • 0034653422 scopus 로고    scopus 로고
    • BDNF regulates eating behavior and locomotor activity in mice
    • Kernie SG, Liebl DJ, Parada LF. BDNF regulates eating behavior and locomotor activity in mice. EMBO J 19: 1290-1300, 2000.
    • (2000) EMBO J , vol.19 , pp. 1290-1300
    • Kernie, S.G.1    Liebl, D.J.2    Parada, L.F.3
  • 29
    • 33744909851 scopus 로고    scopus 로고
    • Neudesin, a secreted factor, promotes neural cell proliferation and neuronal differentiation in mouse neural precursor cells
    • Kimura I, Konishi M, Miyake A, Fujimoto M, Itoh N. Neudesin, a secreted factor, promotes neural cell proliferation and neuronal differentiation in mouse neural precursor cells. J Neurosci Res 83: 1415-1424, 2006.
    • (2006) J Neurosci Res , vol.83 , pp. 1415-1424
    • Kimura, I.1    Konishi, M.2    Miyake, A.3    Fujimoto, M.4    Itoh, N.5
  • 30
    • 42949138989 scopus 로고    scopus 로고
    • Neurotrophic activity of neudesin, a novel extracellular heme-binding protein, is dependent on the binding of heme to its cytochrome b5-like heme/steroid-binding domain
    • Kimura I, Nakayama Y, Yamauchi H, Konishi M, Miyake A, Mori M, Ohta M, Itoh N, Fujimoto M. Neurotrophic activity of neudesin, a novel extracellular heme-binding protein, is dependent on the binding of heme to its cytochrome b5-like heme/steroid-binding domain. J Biol Chem 283: 4323-4331, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 4323-4331
    • Kimura, I.1    Nakayama, Y.2    Yamauchi, H.3    Konishi, M.4    Miyake, A.5    Mori, M.6    Ohta, M.7    Itoh, N.8    Fujimoto, M.9
  • 31
    • 14044276944 scopus 로고    scopus 로고
    • Neudesin, a novel secreted protein with a unique primary structure and neurotrophic activity
    • Kimura I, Yoshioka M, Konishi M, Miyake A, Itoh N. Neudesin, a novel secreted protein with a unique primary structure and neurotrophic activity. J Neurosci Res 79: 287-294, 2005.
    • (2005) J Neurosci Res , vol.79 , pp. 287-294
    • Kimura, I.1    Yoshioka, M.2    Konishi, M.3    Miyake, A.4    Itoh, N.5
  • 33
    • 56849099017 scopus 로고    scopus 로고
    • Central and peripheral regulation of food intake and physical activity: Pathways and genes
    • Lenard NR, Berthoud HR. Central and peripheral regulation of food intake and physical activity: pathways and genes. Obesity (Silver Spring) 16 Suppl 3: S11-S22, 2008.
    • (2008) Obesity (Silver Spring) , vol.16 , Issue.SUPPL. 3
    • Lenard, N.R.1    Berthoud, H.R.2
  • 34
    • 0037135258 scopus 로고    scopus 로고
    • A high-fat, refined sugar diet reduces hippocampal brain-derived neu-rotrophic factor, neuronal plasticity, and learning
    • Molteni R, Barnard RJ, Ying Z, Roberts CK, Gomez-Pinilla F. A high-fat, refined sugar diet reduces hippocampal brain-derived neu-rotrophic factor, neuronal plasticity, and learning. Neuroscience 112: 803-814, 2002.
    • (2002) Neuroscience , vol.112 , pp. 803-814
    • Molteni, R.1    Barnard, R.J.2    Ying, Z.3    Roberts, C.K.4    Gomez-Pinilla, F.5
  • 35
    • 0348048769 scopus 로고    scopus 로고
    • Exercise reverses the harmful effects of consumption of a high-fat diet on synaptic and behavioral plasticity associated to the action of brain-derived neurotrophic factor
    • Molteni R, Wu A, Vaynman S, Ying Z, Barnard RJ, Gomez-Pinilla F. Exercise reverses the harmful effects of consumption of a high-fat diet on synaptic and behavioral plasticity associated to the action of brain-derived neurotrophic factor. Neuroscience 123: 429-440, 2004.
    • (2004) Neuroscience , vol.123 , pp. 429-440
    • Molteni, R.1    Wu, A.2    Vaynman, S.3    Ying, Z.4    Barnard, R.J.5    Gomez-Pinilla, F.6
  • 36
    • 55449100566 scopus 로고    scopus 로고
    • Genetic susceptibility to eating disorders: Associated polymorphisms and pharmacogenetic suggestions
    • Monteleone P, Maj M. Genetic susceptibility to eating disorders: associated polymorphisms and pharmacogenetic suggestions. Pharmacog-enomics 9: 1487-1520, 2008.
    • (2008) Pharmacog-enomics , vol.9 , pp. 1487-1520
    • Monteleone, P.1    Maj, M.2
  • 39
    • 34548694082 scopus 로고    scopus 로고
    • Alpha-melano-cyte stimulating hormone and ghrelin: Central interaction in feeding control
    • Olszewski PK, Bomberg EM, Grace MK, Levine AS. Alpha-melano-cyte stimulating hormone and ghrelin: central interaction in feeding control. Peptides 28: 2084-2089, 2007.
    • (2007) Peptides , vol.28 , pp. 2084-2089
    • Olszewski, P.K.1    Bomberg, E.M.2    Grace, M.K.3    Levine, A.S.4
  • 40
    • 78650052319 scopus 로고    scopus 로고
    • C1q/TNF-related protein-3 (CTRP3), a novel adipokine that regulates hepatic glucose output
    • Peterson JM, Wei Z, Wong GW. C1q/TNF-related protein-3 (CTRP3), a novel adipokine that regulates hepatic glucose output. J Biol Chem 285: 39691-39701, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 39691-39701
    • Peterson, J.M.1    Wei, Z.2    Wong, G.W.3
  • 46
    • 0034792085 scopus 로고    scopus 로고
    • Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity
    • Rios M, Fan G, Fekete C, Kelly J, Bates B, Kuehn R, Lechan RM, Jaenisch R. Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol Endocrinol 15: 1748-1757, 2001.
    • (2001) Mol Endocrinol , vol.15 , pp. 1748-1757
    • Rios, M.1    Fan, G.2    Fekete, C.3    Kelly, J.4    Bates, B.5    Kuehn, R.6    Lechan, R.M.7    Jaenisch, R.8
  • 49
    • 0042357460 scopus 로고    scopus 로고
    • Selectivity in neurotrophin signaling: Theme and variations
    • Segal RA. Selectivity in neurotrophin signaling: theme and variations. Annu Rev Neurosci 26: 299-330, 2003.
    • (2003) Annu Rev Neurosci , vol.26 , pp. 299-330
    • Segal, R.A.1
  • 51
    • 37549055474 scopus 로고    scopus 로고
    • Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity
    • Unger TJ, Calderon GA, Bradley LC, Sena-Esteves M, Rios M. Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity. J Neurosci 27: 14265-14274, 2007.
    • (2007) J Neurosci , vol.27 , pp. 14265-14274
    • Unger, T.J.1    Calderon, G.A.2    Bradley, L.C.3    Sena-Esteves, M.4    Rios, M.5
  • 54
    • 0037343350 scopus 로고    scopus 로고
    • Evidence for a role of the 5-HT2C receptor in central lipopolysaccharide- interleukin-1 beta-, and leptin-induced anorexia
    • von Meyenburg C, Langhans W, Hrupka BJ. Evidence for a role of the 5-HT2C receptor in central lipopolysaccharide-, interleukin-1 beta-, and leptin-induced anorexia. Pharmacol Biochem Behav 74: 1025-1031, 2003.
    • (2003) Pharmacol Biochem Behav , vol.74 , pp. 1025-1031
    • von Meyenburg, C.1    Langhans, W.2    Hrupka, B.J.3
  • 57
    • 1842633557 scopus 로고    scopus 로고
    • The interplay between oxidative stress and brain-derived neurotrophic factor modulates the outcome of a saturated fat diet on synaptic plasticity and cognition
    • Wu A, Ying Z, Gomez-Pinilla F. The interplay between oxidative stress and brain-derived neurotrophic factor modulates the outcome of a saturated fat diet on synaptic plasticity and cognition. Eur J Neurosci 19: 1699-1707, 2004.
    • (2004) Eur J Neurosci , vol.19 , pp. 1699-1707
    • Wu, A.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 60
    • 68949155359 scopus 로고    scopus 로고
    • A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats
    • Zeeni N, Chaumontet C, Moyse E, Fromentin G, Tardivel C, Tome D, Jean A, Darcel N. A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats. Brain Res 1289: 49-55, 2009.
    • (2009) Brain Res , vol.1289 , pp. 49-55
    • Zeeni, N.1    Chaumontet, C.2    Moyse, E.3    Fromentin, G.4    Tardivel, C.5    Tome, D.6    Jean, A.7    Darcel, N.8
  • 62
    • 67649523146 scopus 로고    scopus 로고
    • Appetite control and energy balance regulation in the modern world: Reward-driven brain overrides repletion signals
    • Zheng H, Lenard NR, Shin AC, Berthoud HR. Appetite control and energy balance regulation in the modern world: reward-driven brain overrides repletion signals. Int J Obes (Lond) 33 SUPPL.2: S8-S13, 2009.
    • (2009) Int J Obes (Lond , vol.33 , Issue.SUPPL. 2
    • Zheng, H.1    Lenard, N.R.2    Shin, A.C.3    Berthoud, H.R.4
  • 63
    • 0043030280 scopus 로고    scopus 로고
    • Minireview: From anorexiato obesity-the yin and yang of body weight control
    • Zigman JM, Elmquist JK. Minireview: From anorexia to obesity-the yin and yang of body weight control. Endocrinology 144: 3749-3756, 2003.
    • (2003) Endocrinology , vol.144 , pp. 3749-3756
    • Zigman, J.M.1    Elmquist, J.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.