메뉴 건너뛰기




Volumn 296, Issue 4, 2009, Pages

Effects of BDNF, T3, and corticosterone on expression of the hypothalamic obesity gene network in vivo and in vitro

Author keywords

Anabolic orexigenic; Anorexigenic; Brain derived neurotrophic factor; Catabolic anorexigenic; Fat and lean lines; Glucocorticoids; Obesity; Orexigenic; Thyroid hormone; Triiodothyronine

Indexed keywords

AGOUTI RELATED PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; LEPTIN RECEPTOR; LIOTHYRONINE; PROOPIOMELANOCORTIN; PROTIRELIN; THYROID HORMONE; MESSENGER RNA;

EID: 65949089611     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.90813.2008     Document Type: Article
Times cited : (44)

References (51)
  • 1
    • 34347336424 scopus 로고    scopus 로고
    • Stress, eating and the reward system
    • Adam TC, Epel ES. Stress, eating and the reward system. Physiol Behav 91: 449-458, 2007.
    • (2007) Physiol Behav , vol.91 , pp. 449-458
    • Adam, T.C.1    Epel, E.S.2
  • 2
    • 65949115849 scopus 로고
    • The Yale Journal of Biology and Medicine. Volume XXIV 1951-1952 Hypothalamic control of food intake in rats and cats
    • Brobeck Nutrition classics JR
    • Anand BK, Brobeck Nutrition classics JR. The Yale Journal of Biology and Medicine. Volume XXIV 1951-1952 Hypothalamic control of food intake in rats and cats. Anat Rec 42: 354-356, 1984.
    • (1984) Anat Rec , vol.42 , pp. 354-356
    • Anand, B.K.1
  • 3
    • 0038132090 scopus 로고    scopus 로고
    • A review of neuropeptide and neuroendocrine dysregulation in anorexia and bulimia nervosa
    • Bailer UF, Kaye WH. A review of neuropeptide and neuroendocrine dysregulation in anorexia and bulimia nervosa. Curr Drug Targets CNS Neurol Disord 2: 53-59, 2003.
    • (2003) Curr Drug Targets CNS Neurol Disord , vol.2 , pp. 53-59
    • Bailer, U.F.1    Kaye, W.H.2
  • 4
    • 0031623306 scopus 로고    scopus 로고
    • The MONA LISA hypothesis in the time of leptin
    • Bray GA, York DA. The MONA LISA hypothesis in the time of leptin. Recent Prog Horm Res 53: 95-118, 1998.
    • (1998) Recent Prog Horm Res , vol.53 , pp. 95-118
    • Bray, G.A.1    York, D.A.2
  • 5
    • 0141783618 scopus 로고    scopus 로고
    • Effect of early thyroxine treatment on brain-derived neurotrophic factor mRNA expression and protein amount in the rat medial septum/diagonal band of Broca
    • Camboni D, Roskoden T, Schwegler H. Effect of early thyroxine treatment on brain-derived neurotrophic factor mRNA expression and protein amount in the rat medial septum/diagonal band of Broca. Neurosci Lett 350: 141-144, 2003.
    • (2003) Neurosci Lett , vol.350 , pp. 141-144
    • Camboni, D.1    Roskoden, T.2    Schwegler, H.3
  • 6
    • 0030610680 scopus 로고    scopus 로고
    • Familial aggregation of obesity, candidate genes and quantitative trait loci
    • Chagnon YC, Perusse L, Bouchard C. Familial aggregation of obesity, candidate genes and quantitative trait loci. Curr Opin Lipidol 8: 205-211, 1997.
    • (1997) Curr Opin Lipidol , vol.8 , pp. 205-211
    • Chagnon, Y.C.1    Perusse, L.2    Bouchard, C.3
  • 8
    • 34249951549 scopus 로고    scopus 로고
    • Appetite regulation: An overview
    • Dhillo WS. Appetite regulation: an overview. Thyroid 17: 433-445, 2007.
    • (2007) Thyroid , vol.17 , pp. 433-445
    • Dhillo, W.S.1
  • 9
    • 26244451356 scopus 로고    scopus 로고
    • Potential role of leptin in increase of fatty acid synthase gene expression in chicken liver
    • Dridi S, Buyse J, Decuypere E, Taouis M. Potential role of leptin in increase of fatty acid synthase gene expression in chicken liver. Domest Anim Endocrinol 29: 646-660, 2005.
    • (2005) Domest Anim Endocrinol , vol.29 , pp. 646-660
    • Dridi, S.1    Buyse, J.2    Decuypere, E.3    Taouis, M.4
  • 10
    • 0032751356 scopus 로고    scopus 로고
    • Metabolic differences between genetically lean and fat chickens are partly attributed to the alteration of insulin signaling in liver
    • Dupont J, Chen J, Derouet M, Simon J, Leclercq B, Taouis M. Metabolic differences between genetically lean and fat chickens are partly attributed to the alteration of insulin signaling in liver. J Nutr 129: 1937-1944, 1999.
    • (1999) J Nutr , vol.129 , pp. 1937-1944
    • Dupont, J.1    Chen, J.2    Derouet, M.3    Simon, J.4    Leclercq, B.5    Taouis, M.6
  • 11
    • 0035851907 scopus 로고    scopus 로고
    • Hypothalamic pathways underlying the endocrine, autonomic, and behavioral effects of leptin
    • Elmquist JK. Hypothalamic pathways underlying the endocrine, autonomic, and behavioral effects of leptin. Physiol Behav 74: 703-708, 2001.
    • (2001) Physiol Behav , vol.74 , pp. 703-708
    • Elmquist, J.K.1
  • 12
    • 2442663015 scopus 로고    scopus 로고
    • A mechanism underlying mature-onset obesity: Evidence from the hyperphagic phenotype of brain-derived neurotrophic factor mutants
    • Fox EA, Byerly MS. A mechanism underlying mature-onset obesity: evidence from the hyperphagic phenotype of brain-derived neurotrophic factor mutants. Am J Physiol Regul Integr Comp Physiol 286: R994-R1004, 2004.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Fox, E.A.1    Byerly, M.S.2
  • 14
    • 0023902146 scopus 로고
    • Altered triiodothyronine metabolism in Zucker fatty rats
    • Goldberg JR, Ehrmann B, Katzeff HL. Altered triiodothyronine metabolism in Zucker fatty rats. Endocrinology 122: 689-693, 1988.
    • (1988) Endocrinology , vol.122 , pp. 689-693
    • Goldberg, J.R.1    Ehrmann, B.2    Katzeff, H.L.3
  • 16
    • 0035726527 scopus 로고    scopus 로고
    • BDNF increases the early expression of TRH mRNA in fetal TrkB+ hypothalamic neurons in primary culture
    • Guerra-Crespo M, Ubieta R, Joseph-Bravo P, Charli JL, Perez-Martinez L. BDNF increases the early expression of TRH mRNA in fetal TrkB+ hypothalamic neurons in primary culture. Eur J Neurosci 14: 483-494, 2001.
    • (2001) Eur J Neurosci , vol.14 , pp. 483-494
    • Guerra-Crespo, M.1    Ubieta, R.2    Joseph-Bravo, P.3    Charli, J.L.4    Perez-Martinez, L.5
  • 17
    • 0022521950 scopus 로고
    • Synergism of triiodothyronine and corticosterone on muscle protein breakdown
    • Hayashi K, Kayali AG, Young VR. Synergism of triiodothyronine and corticosterone on muscle protein breakdown. Biochim Biophys Acta 883: 106-111, 1986.
    • (1986) Biochim Biophys Acta , vol.883 , pp. 106-111
    • Hayashi, K.1    Kayali, A.G.2    Young, V.R.3
  • 19
    • 0020740906 scopus 로고
    • Nutrition Classics. The Anatomical Record, Volume 78, 1940: Hypothalamic lesions and adiposity in the rat
    • Hetherington A, Ranson S. Nutrition Classics. The Anatomical Record, Volume 78, 1940: Hypothalamic lesions and adiposity in the rat. Anat Rec 41: 124-127, 1983.
    • (1983) Anat Rec , vol.41 , pp. 124-127
    • Hetherington, A.1    Ranson, S.2
  • 20
    • 0348047587 scopus 로고    scopus 로고
    • Hypothalamic neuropeptide Y/Y1 receptor pathway activated by a reduction in circulating leptin, but not by an increase in circulating ghrelin, contributes to hyperphagia associated with triiodothyronine-induced thyrotoxicosis
    • Ishii S, Kamegai J, Tamura H, Shimizu T, Sugihara H, Oikawa S. Hypothalamic neuropeptide Y/Y1 receptor pathway activated by a reduction in circulating leptin, but not by an increase in circulating ghrelin, contributes to hyperphagia associated with triiodothyronine-induced thyrotoxicosis. Neuroendocrinology 78: 321-330, 2003.
    • (2003) Neuroendocrinology , vol.78 , pp. 321-330
    • Ishii, S.1    Kamegai, J.2    Tamura, H.3    Shimizu, T.4    Sugihara, H.5    Oikawa, S.6
  • 21
    • 0035123756 scopus 로고    scopus 로고
    • Effects of neuropeptides and leptin on nutrient partitioning: Dysregulations in obesity
    • Jeanrenaud B, Rohner-Jeanrenaud F. Effects of neuropeptides and leptin on nutrient partitioning: dysregulations in obesity. Annu Rev Med 52: 339-351, 2001.
    • (2001) Annu Rev Med , vol.52 , pp. 339-351
    • Jeanrenaud, B.1    Rohner-Jeanrenaud, F.2
  • 22
    • 0034653422 scopus 로고    scopus 로고
    • BDNF regulates eating behavior and locomotor activity in mice
    • Kernie SG, Liebl DJ, Parada LF. BDNF regulates eating behavior and locomotor activity in mice. Embo J 19: 1290-1300, 2000.
    • (2000) Embo J , vol.19 , pp. 1290-1300
    • Kernie, S.G.1    Liebl, D.J.2    Parada, L.F.3
  • 23
    • 33646139871 scopus 로고    scopus 로고
    • Induction of brain-derived neurotrophic factor by leptin in the ventromedial hypothalamus
    • Komori T, Morikawa Y, Nanjo K, Senba E. Induction of brain-derived neurotrophic factor by leptin in the ventromedial hypothalamus. Neuroscience 139: 1107-1115, 2006.
    • (2006) Neuroscience , vol.139 , pp. 1107-1115
    • Komori, T.1    Morikawa, Y.2    Nanjo, K.3    Senba, E.4
  • 25
    • 0034455592 scopus 로고    scopus 로고
    • Effects of leptin receptor mutation on Agrp gene expression in fed and fasted lean and obese (LA/N-faf) rats
    • Korner J, Wardlaw SL, Liu SM, Conwell IM, Leibel RL, Chua SC Jr. Effects of leptin receptor mutation on Agrp gene expression in fed and fasted lean and obese (LA/N-faf) rats. Endocrinology 141: 2465-2471, 2000.
    • (2000) Endocrinology , vol.141 , pp. 2465-2471
    • Korner, J.1    Wardlaw, S.L.2    Liu, S.M.3    Conwell, I.M.4    Leibel, R.L.5    Chua Jr., S.C.6
  • 26
    • 0033120846 scopus 로고    scopus 로고
    • Neural sites and pathways regulating food intake in birds: A comparative analysis to mammalian systems
    • Kuenzel WJ, Beck MM, Teruyama R. Neural sites and pathways regulating food intake in birds: a comparative analysis to mammalian systems. J Exp Zool 283: 348-364, 1999.
    • (1999) J Exp Zool , vol.283 , pp. 348-364
    • Kuenzel, W.J.1    Beck, M.M.2    Teruyama, R.3
  • 28
    • 0000188952 scopus 로고
    • Selecting broilers for low or high abdominal fat: Initial observations
    • Leclercq B, Blum JC, Boyer JP. Selecting broilers for low or high abdominal fat: initial observations. Br Poult Sci 21: 107-113, 1980.
    • (1980) Br Poult Sci , vol.21 , pp. 107-113
    • Leclercq, B.1    Blum, J.C.2    Boyer, J.P.3
  • 29
    • 0023735892 scopus 로고
    • Thyroid hormones in genetically lean or fat chickens: Effects of age and triiodothyronine supplementation
    • Leclercq B, Guy G, Rudeaux F. Thyroid hormones in genetically lean or fat chickens: effects of age and triiodothyronine supplementation. Reprod Nutr Dev 28: 931-937, 1988.
    • (1988) Reprod Nutr Dev , vol.28 , pp. 931-937
    • Leclercq, B.1    Guy, G.2    Rudeaux, F.3
  • 30
    • 0022116886 scopus 로고
    • Laying performances, egg composition, and glucose tolerance of genetically lean or fat meat-type breeders
    • Leclercq B, Kouassi-Kouakou J, Simon J. Laying performances, egg composition, and glucose tolerance of genetically lean or fat meat-type breeders. Poult Sci 64: 1609-1616, 1985.
    • (1985) Poult Sci , vol.64 , pp. 1609-1616
    • Leclercq, B.1    Kouassi-Kouakou, J.2    Simon, J.3
  • 31
    • 0001897943 scopus 로고
    • Selecting broilers for low or high abdominal fat - Comparison of energy-metabolism of the lean and fat lines
    • Leclercq B, Saadoun A. Selecting broilers for low or high abdominal fat - comparison of energy-metabolism of the lean and fat lines. Poult Sci 61: 1799-1803, 1982.
    • (1982) Poult Sci , vol.61 , pp. 1799-1803
    • Leclercq, B.1    Saadoun, A.2
  • 33
    • 2942692043 scopus 로고    scopus 로고
    • Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression
    • Abstract
    • Makimura H, Mizuno TM, Isoda F, Beasley J, Silverstein JH, Mobbs CV. Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression (Abstract). BMC Physiol 3: 5, 2003.
    • (2003) BMC Physiol , vol.3 , pp. 5
    • Makimura, H.1    Mizuno, T.M.2    Isoda, F.3    Beasley, J.4    Silverstein, J.H.5    Mobbs, C.V.6
  • 35
  • 37
    • 14844331776 scopus 로고    scopus 로고
    • Ontogeny of pituitary thyrotrophs and regulation by endogenous thyroid hormone feedback in the chick embryo
    • Muchow M, Bossis I, Porter TE. Ontogeny of pituitary thyrotrophs and regulation by endogenous thyroid hormone feedback in the chick embryo. J Endocrinol 184: 407-416, 2005.
    • (2005) J Endocrinol , vol.184 , pp. 407-416
    • Muchow, M.1    Bossis, I.2    Porter, T.E.3
  • 40
    • 0345096658 scopus 로고    scopus 로고
    • Molecular cloning and expression of the turkey leptin receptor gene
    • Richards MP, Poch SM. Molecular cloning and expression of the turkey leptin receptor gene. Comp Biochem Physiol B Biochem Mol Biol 136: 833-847, 2003.
    • (2003) Comp Biochem Physiol B Biochem Mol Biol , vol.136 , pp. 833-847
    • Richards, M.P.1    Poch, S.M.2
  • 41
    • 0034792085 scopus 로고    scopus 로고
    • Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity
    • Rios M, Fan G, Fekete C, Kelly J, Bates B, Kuehn R, Lechan RM, Jaenisch R. Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol Endocrinol 15: 1748-1757, 2001.
    • (2001) Mol Endocrinol , vol.15 , pp. 1748-1757
    • Rios, M.1    Fan, G.2    Fekete, C.3    Kelly, J.4    Bates, B.5    Kuehn, R.6    Lechan, R.M.7    Jaenisch, R.8
  • 42
    • 0023279254 scopus 로고
    • In vivo lipogenesis of genetically lean and fat chickens: Effects of nutritional state and dietary fat
    • Saadoun A, Leclercq B. In vivo lipogenesis of genetically lean and fat chickens: effects of nutritional state and dietary fat. J Nutr 117: 428-435, 1987.
    • (1987) J Nutr , vol.117 , pp. 428-435
    • Saadoun, A.1    Leclercq, B.2
  • 43
    • 0019992944 scopus 로고
    • Quantitative analysis of growth and myelination of cutaneous nerve fibers in the chick
    • Saxod R, Bouvet J. Quantitative analysis of growth and myelination of cutaneous nerve fibers in the chick. Dev Neurosci 5: 143-155, 1982.
    • (1982) Dev Neurosci , vol.5 , pp. 143-155
    • Saxod, R.1    Bouvet, J.2
  • 45
    • 0020434321 scopus 로고
    • Longitudinal study of adiposity in chickens selected for high or low abdominal fat content: Further evidence of a glucose-insulin imbalance in the fat line
    • Simon J, Leclercq B. Longitudinal study of adiposity in chickens selected for high or low abdominal fat content: further evidence of a glucose-insulin imbalance in the fat line. J Nutr 112: 1961-1973, 1982.
    • (1982) J Nutr , vol.112 , pp. 1961-1973
    • Simon, J.1    Leclercq, B.2
  • 46
    • 0019445783 scopus 로고
    • Evidence of a glucose-insulin imbalance and effect of dietary protein and energy level in chickens selected for high abdominal fat content
    • Touchburn S, Simon J, Leclercq B. Evidence of a glucose-insulin imbalance and effect of dietary protein and energy level in chickens selected for high abdominal fat content. J Nutr 111: 325-335, 1981.
    • (1981) J Nutr , vol.111 , pp. 325-335
    • Touchburn, S.1    Simon, J.2    Leclercq, B.3
  • 47
    • 34548825102 scopus 로고    scopus 로고
    • BDNF up-regulates pre-pro-TRH mRNA expression in the fetal/neonatal paraventricular nucleus of the hypothalamus. Properties of the transduction pathway
    • Ubieta R, Uribe RM, Gonzalez JA, Garcia-Vazquez A, Perez-Monter C, Perez-Martinez L, Joseph-Bravo P, Charli JL. BDNF up-regulates pre-pro-TRH mRNA expression in the fetal/neonatal paraventricular nucleus of the hypothalamus. Properties of the transduction pathway. Brain Res 1174: 28-38, 2007.
    • (2007) Brain Res , vol.1174 , pp. 28-38
    • Ubieta, R.1    Uribe, R.M.2    Gonzalez, J.A.3    Garcia-Vazquez, A.4    Perez-Monter, C.5    Perez-Martinez, L.6    Joseph-Bravo, P.7    Charli, J.L.8
  • 48
    • 37549055474 scopus 로고    scopus 로고
    • Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity
    • Unger TJ, Calderon GA, Bradley LC, Sena-Esteves M, Rios M. Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity. J Neurosci 27: 14265-14274, 2007.
    • (2007) J Neurosci , vol.27 , pp. 14265-14274
    • Unger, T.J.1    Calderon, G.A.2    Bradley, L.C.3    Sena-Esteves, M.4    Rios, M.5
  • 49
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • Abstract. RESEARCH0034
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes (Abstract). Genome Biol 3: RESEARCH0034, 2002.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 51
    • 0028199062 scopus 로고
    • Half-site arrangement of hybrid glucocorticoid and thyroid hormone response elements specifies thyroid hormone receptor complex binding to DNA and transcriptional activity
    • Yen PM, Ikeda M, Wilcox EC, Brubaker JH, Spanjaard RA, Sugawara A, Chin WW. Half-site arrangement of hybrid glucocorticoid and thyroid hormone response elements specifies thyroid hormone receptor complex binding to DNA and transcriptional activity. J Biol Chem 269: 12704-12709, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 12704-12709
    • Yen, P.M.1    Ikeda, M.2    Wilcox, E.C.3    Brubaker, J.H.4    Spanjaard, R.A.5    Sugawara, A.6    Chin, W.W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.