Neurotrophic activity of neudesin, a novel extracellular heme-binding protein, is dependent on the binding of heme to its cytochrome b 5-like heme/steroid-binding domain

Journal of Biological Chemistry

Volumn 283, Issue 7, 2008, Pages 4323-4331

  Kimura, Ikuo ^a   Nakayama, Yoshiaki ^b   Yamauchi, Hajime ^b   Konishi, Morichika ^b   Miyake, Ayumi ^b   Mori, Masahiro ^a   Ohta, Mitsuhiro ^c   Itoh, Nobuyuki ^b   Fujimoto, Masafumi ^a  

^a CHIBA INSTITUTE OF SCIENCE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; HEMOGLOBIN; IRON COMPOUNDS; NEURONS; NUCLEIC ACIDS; PURIFICATION; RNA;

ABSORBANCE PEAKS; AFFINITY COLUMNS; BINDING DOMAINS; BINDING PROTEINS; CELL SURVIVALS; CULTURE MEDIUMS; CULTURED NEURONS; CYTOCHROME B; EXTRACELLULAR; MUTANT LACKING; NEURAL CELLS; NEUROTROPHIC ACTIVITIES; PROTOPORPHYRIN IX; RNA INTERFERENCES; SECRETED PROTEINS; TRANSDUCING;

PORPHYRINS;

BINDING PROTEIN; CYTOCHROME B5; HEMATIN; HEME; HEMIN; NEUDESIN; NEUROTROPHIC FACTOR; PROTOPORPHYRIN; UNCLASSIFIED DRUG; NERVE PROTEIN; NEUDESIN PROTEIN, MOUSE; PRIMER DNA; SMALL INTERFERING RNA; STEROID;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BRAIN CELL; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; MOUSE; NERVE CELL CULTURE; NEUROTROPISM; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; STEROID BINDING; ANIMAL; BRAIN CORTEX; CHEMISTRY; CYTOLOGY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN BINDING; SEQUENCE HOMOLOGY; TUMOR CELL LINE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; CEREBRAL CORTEX; CYTOCHROMES B5; DNA PRIMERS; HEME; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PROTEIN BINDING; RNA, SMALL INTERFERING; SEQUENCE HOMOLOGY, AMINO ACID; STEROIDS;

EID: 42949138989     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M706679200     Document Type: Article

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