Baculovirus expression: Tackling the complexity challenge

Current Opinion in Structural Biology

Volumn 23, Issue 3, 2013, Pages 357-364

  Barford, David ^a   Takagi, Yuichiro ^b   Schultz, Patrick ^c,d   Berger, Imre ^e,f  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^d INSERM   (France)

^e UNIVERSITÉ DE STRASBOURG   (France)

^f EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX PROTEIN; MULTIPROTEIN COMPLEX; RNA POLYMERASE II; TRANSCRIPTION FACTOR IID; UNCLASSIFIED DRUG;

BACULOVIRUS; BACULOVIRUS EXPRESSION SYSTEM; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CRYSTAL STRUCTURE; ELECTRON MICROSCOPY; EXPRESSION VECTOR; HUMAN; INSECT CELL; MITOSIS; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; REVIEW; SACCHAROMYCES CEREVISIAE; STOICHIOMETRY; TRANSCRIPTION REGULATION; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS RECOMBINANT; X RAY CRYSTALLOGRAPHY;

ANAPHASE-PROMOTING COMPLEX-CYCLOSOME; ANIMALS; BACULOVIRIDAE; CLONING, MOLECULAR; GENETIC VECTORS; HUMANS; INSECTS; MEDIATOR COMPLEX; MULTIPROTEIN COMPLEXES; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA;

EID: 84879145033     PISSN: 0959440X     EISSN: 1879033X     Source Type: Journal    
DOI: 10.1016/j.sbi.2013.03.009     Document Type: Review

References (58)

1. Bieniossek C., Imasaki T., Takagi Y., Berger I. MultiBac: expanding the research toolbox for multiprotein complexes. Trends Biochem Sci 2012, 37:49-57.
2. Kornberg R.D. Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 2005, 30:235.
3. Boube M., Joulia L., Cribbs D.L., Bourbon H.M. Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man. Cell 2002, 110:143-151.
4. Bourbon H.M. Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex. Nucleic Acids Res 2008, 36:3993-4008.
5. Kim Y.J., Bjorklund S., Li Y., Sayre M.H., Kornberg R.D. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 1994, 77:599-608.
6. Bjorklund S., Gustafsson C.M. The yeast Mediator complex and its regulation. Trends Biochem Sci 2005, 30:240-244.
7. Guglielmi B., van Berkum N.L., Klapholz B., Bijma T., Boube M., Boschiero C., Bourbon H.M., Holstege F.C., Werner M. A high resolution protein interaction map of the yeast Mediator complex. Nucleic Acids Res 2004, 32:5379-5391.
8. Conaway R.C., Sato S., Tomomori-Sato C., Yao T., Conaway J.W. The mammalian Mediator complex and its role in transcriptional regulation. Trends Biochem Sci 2005, 30:250-255.
9. Malik S., Roeder R.G. The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nat Rev Genet 2010, 11:761-772.
10. Firestein R., Bass A.J., Kim S.Y., Dunn I.F., Silver S.J., Guney I., Freed E., Ligon A.H., Vena N., Ogino S., et al. CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature 2008, 455:547-551.
11. Rump P., Niessen R.C., Verbruggen K.T., Brouwer O.F., de Raad M., Hordijk R. A novel mutation in MED12 causes FG syndrome (Opitz-Kaveggia syndrome). Clin Genet 2011, 79:183-188.
12. Graham J.M., Visootsak J., Dykens E., Huddleston L., Clark R.D., Jones K.L., Moeschler J.B., Opitz J.M., Morford J., Simensen R., et al. Behavior of 10 patients with FG syndrome (Opitz-Kaveggia syndrome) and the p.R961W mutation in the MED12 gene. Am J Med Genet A 2008, 146A:3011-3017.
13. Makinen N., Mehine M., Tolvanen J., Kaasinen E., Li Y., Lehtonen H.J., Gentile M., Yan J., Enge M., Taipale M., et al. MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas. Science 2011, 334:252-255.
14. Berti L., Mittler G., Przemeck G.K., Stelzer G., Gunzler B., Amati F., Conti E., Dallapiccola B., Hrabe de Angelis M., Novelli G., et al. Isolation and characterization of a novel gene from the DiGeorge chromosomal region that encodes for a mediator subunit. Genomics 2001, 74:320-332.
15. Kaufmann R., Straussberg R., Mandel H., Fattal-Valevski A., Ben-Zeev B., Naamati A., Shaag A., Zenvirt S., Konen O., Mimouni-Bloch A., et al. Infantile cerebral and cerebellar atrophy is associated with a mutation in the MED17 subunit of the transcription preinitiation mediator complex. Am J Hum Genet 2010, 87:667-670.
16. Hashimoto S., Boissel S., Zarhrate M., Rio M., Munnich A., Egly J.M., Colleaux L. MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. Science 2011, 333:1161-1163.
17. Cai G., Imasaki T., Takagi Y., Asturias F.J. Mediator structural conservation and implications for the regulation mechanism. Structure 2009, 17:559-567.
18. Davis J.A., Takagi Y., Kornberg R.D., Asturias F.A. Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction. Mol Cell 2002, 10:409-415.
19. Li Y., Bjorklund S., Jiang Y.W., Kim Y.J., Lane W.S., Stillman D.J., Kornberg R.D. Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A 1995, 92:10864-10868.
20. Lee Y.C., Kim Y.J. Requirement for a functional interaction between mediator components Med6 and Srb4 in RNA polymerase II transcription. Mol Cell Biol 1998, 18:5364-5370.
21. Lee Y.C., Park J.M., Min S., Han S.J., Kim Y.J. An activator binding module of yeast RNA polymerase II holoenzyme. Mol Cell Biol 1999, 19:2967-2976.
22. Conaway R.C., Conaway J.W. Origins and activity of the Mediator complex. Semin Cell Dev Biol 2011, 22:729-734.
23. Thompson C.M., Koleske A.J., Chao D.M., Young R.A. A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 1993, 73:1361-1375.
24. Hengartner C.J., Thompson C.M., Zhang J., Chao D.M., Liao S.M., Koleske A.J., Okamura S., Young R.A. Association of an activator with an RNA polymerase II holoenzyme. Genes Dev 1995, 9:897-910.
25. Taatjes D.J. The human Mediator complex: a versatile, genome-wide regulator of transcription. Trends Biochem Sci 2010, 35:315-322.
26. Balamotis M.A., Pennella M.A., Stevens J.L., Wasylyk B., Belmont A.S., Berk A.J. Complexity in transcription control at the activation domain-mediator interface. Sci Signal 2009, 2:ra20.
27. Koh S.S., Ansari A.Z., Ptashne M., Young R.A. An activator target in the RNA polymerase II holoenzyme. Mol Cell 1998, 1:895-904.
28. Takagi Y., Calero G., Komori H., Brown J.A., Ehrensberger A.H., Hudmon A., Asturias F., Kornberg R.D. Head module control of mediator interactions. Mol Cell 2006, 23:355-364.
29. Cai G., Imasaki T., Yamada K., Cardelli F., Takagi Y., Asturias F.J. Mediator head module structure and functional interactions. Nat Struct Mol Biol 2010, 17:273-279.
30. Imasaki T., Calero G., Cai G., Tsai K.L., Yamada K., Cardelli F., Erdjument-Bromage H., Tempst P., Berger I., Kornberg G.L., et al. Architecture of the Mediator head module. Nature 2011, 475:240-243.
31. Pines J. Cubism and the cell cycle: the many faces of the APC/C. Nat Rev Mol Cell Biol 2011, 12:427-438.
32. Sullivan M., Morgan D.O. Finishing mitosis, one step at a time. Nat Rev Mol Cell Biol 2007, 8:894-903.
33. Barford D Structural insights into anaphase-promoting complex function and mechanism. Philos Trans R Soc Lond B Biol Sci 2011, 366:3605-3624.
34. Schreiber A., Stengel F., Zhang Z., Enchev R.I., Kong E.H., Morris E.P., Robinson C.V., da Fonseca P.C., Barford D. Structural basis for the subunit assembly of the anaphase-promoting complex. Nature 2011, 470:227-232.
35. Zhang Z., Yang J., Kong E.H., Chao W.C., Morris E.P., da Fonseca P.C., Barford D. Recombinant expression, reconstitution and structure of human Anaphase Promoting Complex (APC/C). Biochem J 2013, 449:365-371.
36. Berger I., Fitzgerald D.J., Richmond T.J. Baculovirus expression system for heterologous multiprotein complexes. Nat Biotechnol 2004, 22:1583-1587.
37. Bieniossek C., Richmond T.J., Berger I. MultiBac: multigene baculovirus-based eukaryotic protein complex production. Curr Protoc Protein Sci. 2008, 5:20. (chapter 5).
38. Fitzgerald D.J., Berger P., Schaffitzel C., Yamada K., Richmond T.J., Berger I. Protein complex expression by using multigene baculoviral vectors. Nat Methods 2006, 3:1021-1032.
39. Fitzgerald D.J., Schaffitzel C., Berger P., Wellinger R., Bieniossek C., Richmond T.J., Berger I. Multiprotein expression strategy for structural biology of eukaryotic complexes. Structure 2007, 15:275-279.
40. Trowitzsch S., Bieniossek C., Nie Y., Garzoni F., Berger I. New baculovirus expression tools for recombinant protein complex production. J Struct Biol 2010, 172:45-54.
41. Vijayachandran L.S., Viola C., Garzoni F., Trowitzsch S., Bieniossek C., Chaillet M., Schaffitzel C., Busso D., Romier C., Poterszman A., et al. Robots, pipelines, polyproteins: enabling multiprotein expression in prokaryotic and eukaryotic cells. J Struct Biol 2011, 175:198-208.
42. Thornton B.R., Ng T.M., Matyskiela M.E., Carroll C.W., Morgan D.O., Toczyski D.P. An architectural map of the anaphase-promoting complex. Genes Dev 2006, 20:449-460.
43. Zhang Z., Kulkarni K., Hanrahan S.J., Thompson A.J., Barford D. The APC/C subunit Cdc16/Cut9 is a contiguous tetratricopeptide repeat superhelix with a homo-dimer interface similar to Cdc27. EMBO J 2010, 29:3733-3744.
44. da Fonseca P.C., Kong E.H., Zhang Z., Schreiber A., Williams M.A., Morris E.P., Barford D. Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor. Nature 2011, 470:274-278.
45. Uzunova K., Dye B.T., Schutz H., Ladurner R., Petzold G., Toyoda Y., Jarvis M.A., Brown N.G., Poser I., Novatchkova M., et al. APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex. Nat Struct Mol Biol 2012, 19:1116-1123.
46. Bitinaite J., Rubino M., Varma K.H., Schildkraut I., Vaisvila R., Vaiskunaite R. USER friendly DNA engineering and cloning method by uracil excision. Nucleic Acids Res 2007, 35:1992-2002.
47. Geu-Flores F., Nour-Eldin H.H., Nielsen M.T., Halkier B.A. USER fusion: a rapid and efficient method for simultaneous fusion and cloning of multiple PCR products. Nucleic Acids Res 2007, 35:e55.
48. Hutchins J.R., Toyoda Y., Hegemann B., Poser I., Heriche J.K., Sykora M.M., Augsburg M., Hudecz O., Buschhorn B.A., Bulkescher J., et al. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science 2010, 328:593-599.
49. Musacchio A., Salmon E.D. The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol 2007, 8:379-393.
50. Chao W.C., Kulkarni K., Zhang Z., Kong E.H., Barford D. Structure of the mitotic checkpoint complex. Nature 2012, 484:208-213.
51. Herzog F., Primorac I., Dube P., Lenart P., Sander B., Mechtler K., Stark H., Peters J.M. Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. Science 2009, 323:1477-1481.
52. Cler E., Papai G., Schultz P., Davidson I. Recent advances in understanding the structure and function of general transcription factor TFIID. Cell Mol Life Sci 2009, 66:2123-2134.
53. Müller F., Zaucker A., Tora L. Developmental regulation of transcription initiation: more than just changing the actors. Curr Opin Genet Dev 2010, 20:533-540.
54. Papai G., Weil P.A., Schultz P. New insights into the function of transcription factor TFIID from recent structural studies. Curr Opin Genet Dev 2011, 21:219-224.
55. Wright K.J., Marr MT2nd, Tjian R. TAF4 nucleates a core subcomplex of TFIID and mediates activated transcription from a TATA-less promoter. Proc Natl Acad Sci U S A 2006, 103:12347-12352.
56. Papai G., Tripathi M.K., Ruhlmann C., Werten S., Crucifix C., Weil P.A., Schultz P. Mapping the initiator binding Taf2 subunit in the structure of hydrated yeast TFIID. Structure 2009, 17:363-373.
57. Bieniossek C., Papai G., Schaffitzel C., Garzoni F., Chaillet M., Scheer E., Papadopoulos P., Tora L., Schultz P., Berger I. The architecture of human general transcription factor TFIID core complex. Nature 2013, 493:699-702.
58. Sharon M., Robinson C.V. The role of mass spectrometry in structure elucidation of dynamic protein complexes. Annu Rev Biochem 2007, 76:167-193.