Oxidative stress modulates osteoblastic differentiation of vascular and bone cells

Free Radical Biology and Medicine

Volumn 31, Issue 4, 2001, Pages 509-519

  Mody, Nilam ^a   Parhami, Farhad ^a   Sarafian, Theodore A ^a   Demer, Linda L ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antioxidants; Free radicals; Hydrogen peroxide; Minimally oxidized low density lipoprotein; Osteoblastic differentiation; Reactive oxygen species; Xanthine xanthine oxidase

Indexed keywords

ALKALINE PHOSPHATASE; FLUORESCEIN; HYDROGEN PEROXIDE; LOW DENSITY LIPOPROTEIN; TROLOX C; XANTHINE; XANTHINE OXIDASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL CALCIFICATION; BONE CELL; CELL ACTIVITY; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; MINERALIZATION; MOUSE; NONHUMAN; OSTEOPOROSIS; OXIDATIVE STRESS; PRIORITY JOURNAL; TISSUE DIFFERENTIATION;

ALKALINE PHOSPHATASE; ANIMALS; BONE MARROW CELLS; CALCIUM; CATTLE; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; FORMAZANS; HYDROGEN PEROXIDE; LIPOPROTEINS, LDL; MICE; MUSCLE, SMOOTH, VASCULAR; OSTEOBLASTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDES; TETRAZOLIUM SALTS; XANTHINE; XANTHINE OXIDASE;

EID: 0035882483     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00610-4     Document Type: Article

References (52)

1. Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: Evidence that antioxidant in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit
2. Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation
3. Active oxygen species and the functions of phagocytic leukocytes
4. Bradykinin induces generation of reactive oxygen species in bovine aortic endothelial cells
5. Effect of hypoxia and reoxygenation on the formation and release of reactive oxygen species by porcine pulmonary artery endothelial cells
6. Hypercholesterolemia increases endothelial superoxide anion production
7. Oxidized low-density lipoprotein increases the production of intracellular reactive oxygen species in endothelial cells; inhibitory effect of lacidipine
8. Leptin induces oxidative stress in human endothelial cells
9. Redox control of vascular smooth muscle proliferation
10. 2 for platelet-derived growth factor signal transduction
11. Redox control of gene expression by eukaryotic transcription factors NF-κB, AP-1 and SRF/TCF
12. TGF-β1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify
13. Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation: A possible explanation for the paradox of arterial calcification in osteoporotic patients
14. Effect of degenerative spinal and aortic calcification on bone density measurements in post-menopausal women: Links between osteoporosis and cardiovascular disease?
15. Age-related loss of bone mass and aortic/aortic valve calcification - Re-evaluation of recommended dietary allowance of calcium in the elderly
16. Evidence for a diminished maturation of preosteoblasts into osteoblasts during aging in rats: An ultrastructural analysis
17. Relationship between bone formation rate and osteoblast surface on different subdivisions of the endosteal envelope in aging and osteoporosis
18. Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo
19. Hydrogen peroxide, but not superoxide, stimulates bone resorption in mouse calvariae
20. Atherogenic diet and minimally oxidized low density lipoprotein inhibit osteogenic and promote adipogenic differentiation of marrow stromal cells
21. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
22. Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate
23. bcl-2 expression decreases methyl mercury-induced free-radical generation and cell killing in a neural cell line
24. Evidence for free radical formation during the oxidation of 2′-7′-dichlorofluorescin to the fluorescent dye 2′-7′-dichlorofluorescin by horseradish peroxidase: Possible implications for oxidative stress measurements
25. Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype
26. Overexpression of human catalase gene decreases oxidized lipid-induced cytotoxicity in vascular smooth muscle cells
27. Effects of pyrrolidine dithiocarbamate on endothelial cells: Protection against oxidative stress
28. Pyrrolidine dithiocarbamate attenuates endotoxin-induced acute lung injury
29. Trolox inhibits peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes
30. Quantification of total oxidant scavenging capacity of antioxidants for peroxynitrite, peroxyl radicals, and hydroxyl radicals
31. Oxidative stress as a causal factor in differentiation and aging: A unifying hypothesis
32. Apoptosis, redifferentiation and arresting proliferation simultaneously triggered by oxidative stress in human hepatoma cells
33. Reactive oxygen species activate human peripheral blood dendritic cells
34. 2-terminal kinase)
35. 2 and phosphorylation of 30 kilodalton proteins as early responses of cell cycle-dependent inhibition of DNA synthesis by transforming growth factor beta 1
36. Inhibition of TGF-beta receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass
37. Osteoblastic responses to TGF-β during bone remodeling
38. Nitric oxide is a regulator of bone remodeling
39. NADPH-oxidase expression and in situ production of superoxide by osteoclasts actively resorbing bone
40. Nitroblue tetrazolium reduction and bone resorption by osteoclasts in vitro inhibited by a manganese-based superoxide dismutase mimic
41. 2-derived free radicals treated fibronectin substratum reduces the bone nodule formation of rat calvarial osteoblast
42. α-Tocopherol and trolox block the early intracellular events (TBARS and calcium rises) elicited by oxidized low density lipoproteins in cultured endothelial cells
43. 2-Mercaptoethanol restores the ability of nuclear factor kappa B (NFκB) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC). Evidence for oxidation of glutathione in the mechanism of inhibition of NFκB by PDTC
44. Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells
45. Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper
46. Role of oxidants and antioxidants in the induction of AP-1, NF-κB, and glutathione S-transferase gene expression
47. Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress
48. 2,7-Dihydrodichlorofluorescein diacetate as a fluorescent marker for peroxynitrite formation
49. Phenoxyl free radical formation during the oxidation of the fluorescent dye 2′,7′-dichlorofluorescein by horseradish peroxidase
50. Lymphocyte populations in atherosclerotic lesions of apoE -/- and LDL receptor -/- mice. Decreasing density with disease progression
51. Lipid clearing agents in steroid-induced osteoporosis
52. Vitamin E stimulates trabecular bone formation and alters epiphyseal cartilage morphometry