-
1
-
-
77449110096
-
Cracking the phosphatase code: docking interactions determine substrate specificity
-
Roy J, Cyert MS, (2009) Cracking the phosphatase code: docking interactions determine substrate specificity. Science Signalling 2: re9.
-
(2009)
Science Signalling
, vol.2
-
-
Roy, J.1
Cyert, M.S.2
-
2
-
-
70350340056
-
Serine/threonine phosphatases: mechanism through structure
-
Shi Y, (2009) Serine/threonine phosphatases: mechanism through structure. Cell 139: 468.
-
(2009)
Cell
, vol.139
, pp. 468
-
-
Shi, Y.1
-
3
-
-
0033779701
-
Calcineurin: form and function
-
Rusnak F, Mertz P, (2000) Calcineurin: form and function. Physiological reviews 80: 1483-1521.
-
(2000)
Physiological Reviews
, vol.80
, pp. 1483-1521
-
-
Rusnak, F.1
Mertz, P.2
-
4
-
-
0033804760
-
The role of calcineurin in lymphocyte activation
-
Baksh S, Burakoff SJ, (2000) The role of calcineurin in lymphocyte activation. 12 (4): 405-415.
-
(2000)
, vol.12
, Issue.4
, pp. 405-415
-
-
Baksh, S.1
Burakoff, S.J.2
-
5
-
-
0031789983
-
Signal-transduction cascades as targets for therapeutic intervention by natural products
-
Cardenas ME, Sanfridson A, Cutler NS, Heitman J, (1998) Signal-transduction cascades as targets for therapeutic intervention by natural products. Trends in biotechnology 16: 427-433.
-
(1998)
Trends in Biotechnology
, vol.16
, pp. 427-433
-
-
Cardenas, M.E.1
Sanfridson, A.2
Cutler, N.S.3
Heitman, J.4
-
6
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
-
Schreiber SL, (1991) Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66: 807-815.
-
(1991)
Cell
, vol.66
, pp. 807-815
-
-
Schreiber, S.L.1
-
7
-
-
0141642015
-
c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling
-
Liang Q, Bueno OF, Wilkins BJ, Kuan CY, Xia Y, et al. (2003) c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling. The EMBO journal 22: 5079-5089.
-
(2003)
The EMBO Journal
, vol.22
, pp. 5079-5089
-
-
Liang, Q.1
Bueno, O.F.2
Wilkins, B.J.3
Kuan, C.Y.4
Xia, Y.5
-
9
-
-
0027527305
-
Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology
-
Bierer BE, Holländer G, Fruman D, Burakoff SJ, (1993) Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology. Current opinion in immunology 5: 763-773.
-
(1993)
Current Opinion in Immunology
, vol.5
, pp. 763-773
-
-
Bierer, B.E.1
Holländer, G.2
Fruman, D.3
Burakoff, S.J.4
-
10
-
-
0027772408
-
Calcineurin Is a Key Signaling Enzyme in T Lymphocyte Activation and the Target of the Immunosuppressive Drugs Cyclosporin A and FK506a
-
Clipstone NA, Crabtree GR, (1993) Calcineurin Is a Key Signaling Enzyme in T Lymphocyte Activation and the Target of the Immunosuppressive Drugs Cyclosporin A and FK506a. Annals of the New York Academy of Sciences 696: 20-30.
-
(1993)
Annals of the New York Academy of Sciences
, vol.696
, pp. 20-30
-
-
Clipstone, N.A.1
Crabtree, G.R.2
-
11
-
-
0029797189
-
The mechanism of action of cyclosporin A and FK506
-
Ho S, Clipstone N, Timmermann L, Northrop J, Graef I, et al. (1996) The mechanism of action of cyclosporin A and FK506. Clinical immunology and immunopathology 80: S40-S45.
-
(1996)
Clinical Immunology and Immunopathology
, vol.80
-
-
Ho, S.1
Clipstone, N.2
Timmermann, L.3
Northrop, J.4
Graef, I.5
-
12
-
-
0037323992
-
Calcineurin phosphatase activity and immunosuppression. A review on the role of calcineurin phosphatase activity and the immunosuppressive effect of cyclosporin A and tacrolimus
-
Jørgensen KA, Koefoed-Nielsen P, Karamperis N, (2003) Calcineurin phosphatase activity and immunosuppression. A review on the role of calcineurin phosphatase activity and the immunosuppressive effect of cyclosporin A and tacrolimus. Scandinavian journal of immunology 57: 93-98.
-
(2003)
Scandinavian Journal of Immunology
, vol.57
, pp. 93-98
-
-
Jørgensen, K.A.1
Koefoed-Nielsen, P.2
Karamperis, N.3
-
13
-
-
0034023906
-
Immunosuppressive agents in organ transplantation: past, present, and future
-
Hong JC, Kahan BD, (2000) Immunosuppressive agents in organ transplantation: past, present, and future. 20 (2): 108.
-
(2000)
, vol.20
, Issue.2
, pp. 108
-
-
Hong, J.C.1
Kahan, B.D.2
-
14
-
-
52949137354
-
Medicinal properties of mangosteen (Garcinia mangostana)
-
Pedraza-Chaverri J, Cárdenas-Rodríguez N, Orozco-Ibarra M, Pérez-Rojas JM, (2008) Medicinal properties of mangosteen (Garcinia mangostana). Food and chemical toxicology 46: 3227-3239.
-
(2008)
Food and Chemical Toxicology
, vol.46
, pp. 3227-3239
-
-
Pedraza-Chaverri, J.1
Cárdenas-Rodríguez, N.2
Orozco-Ibarra, M.3
Pérez-Rojas, J.M.4
-
15
-
-
76949102296
-
New medicinal properties of mangostins: Analgesic activity and pharmacological characterization of active ingredients from the fruit hull of Garcinia mangostana L
-
Cui J, Hu W, Cai Z, Liu Y, Li S, et al. (2010) New medicinal properties of mangostins: Analgesic activity and pharmacological characterization of active ingredients from the fruit hull of Garcinia mangostana L. Pharmacology Biochemistry and Behavior 95: 166-172.
-
(2010)
Pharmacology Biochemistry and Behavior
, vol.95
, pp. 166-172
-
-
Cui, J.1
Hu, W.2
Cai, Z.3
Liu, Y.4
Li, S.5
-
16
-
-
34147189022
-
Phenolics from hull of Garcinia mangostana fruit and their antioxidant activities
-
Yu L, Zhao M, Yang B, Zhao Q, Jiang Y, (2007) Phenolics from hull of Garcinia mangostana fruit and their antioxidant activities. Food Chemistry 104: 176-181.
-
(2007)
Food Chemistry
, vol.104
, pp. 176-181
-
-
Yu, L.1
Zhao, M.2
Yang, B.3
Zhao, Q.4
Jiang, Y.5
-
17
-
-
79952535147
-
Quercetin binds to calcineurin at a similar region to cyclosporin A and tacrolimus
-
Lei H, Luo J, Tong L, Peng L, Qi Y, et al. (2011) Quercetin binds to calcineurin at a similar region to cyclosporin A and tacrolimus. Food Chemistry 127: 1169-1174.
-
(2011)
Food Chemistry
, vol.127
, pp. 1169-1174
-
-
Lei, H.1
Luo, J.2
Tong, L.3
Peng, L.4
Qi, Y.5
-
18
-
-
67349201766
-
Studies on the interactions of kaempferol to calcineurin by spectroscopic methods and docking
-
Lei H, Qi Y, Jia Z, Lin W, Wei Q, (2009) Studies on the interactions of kaempferol to calcineurin by spectroscopic methods and docking. Biochimica et Biophysica Acta (BBA)-Proteins & Proteomics 1794: 1269-1275.
-
(2009)
Biochimica Et Biophysica Acta (BBA)-Proteins & Proteomics
, vol.1794
, pp. 1269-1275
-
-
Lei, H.1
Qi, Y.2
Jia, Z.3
Lin, W.4
Wei, Q.5
-
19
-
-
77957022665
-
Immunosuppressive activity on the murine immune responses of glycyrol from Glycyrrhiza uralensis via inhibition of calcineurin activity
-
Li J, Tu Y, Tong L, Zhang W, Zheng J, et al. (2010) Immunosuppressive activity on the murine immune responses of glycyrol from Glycyrrhiza uralensis via inhibition of calcineurin activity. Pharmaceutical biology 48: 1177-1184.
-
(2010)
Pharmaceutical Biology
, vol.48
, pp. 1177-1184
-
-
Li, J.1
Tu, Y.2
Tong, L.3
Zhang, W.4
Zheng, J.5
-
20
-
-
79951988180
-
Interaction of glycyrol with calcineurin A studied by spectroscopic methods and docking
-
Peng L, Qi Y, Wu H, Wei Q, (2011) Interaction of glycyrol with calcineurin A studied by spectroscopic methods and docking. IUBMB life 63: 14-20.
-
(2011)
IUBMB Life
, vol.63
, pp. 14-20
-
-
Peng, L.1
Qi, Y.2
Wu, H.3
Wei, Q.4
-
21
-
-
76949108466
-
Inhibition of calcineurin by quercetin in vitro and in Jurkat cells
-
Wang H, Zhou CL, Lei H, Wei Q, (2010) Inhibition of calcineurin by quercetin in vitro and in Jurkat cells. Journal of biochemistry 147: 185-190.
-
(2010)
Journal of Biochemistry
, vol.147
, pp. 185-190
-
-
Wang, H.1
Zhou, C.L.2
Lei, H.3
Wei, Q.4
-
22
-
-
52049122868
-
Kaempferol: a new immunosuppressant of calcineurin
-
Wang H, Zhou CL, Lei H, Zhang SD, Zheng J, et al. (2008) Kaempferol: a new immunosuppressant of calcineurin. IUBMB life 60: 549-554.
-
(2008)
IUBMB Life
, vol.60
, pp. 549-554
-
-
Wang, H.1
Zhou, C.L.2
Lei, H.3
Zhang, S.D.4
Zheng, J.5
-
23
-
-
34347388388
-
The regulatory domains of CNA have different effects on the inhibition of CN activity by FK506 and CsA
-
Wang H, Du Y, Xiang B, Lin W, Wei Q, (2008) The regulatory domains of CNA have different effects on the inhibition of CN activity by FK506 and CsA. IUBMB life 59: 388-393.
-
(2008)
IUBMB Life
, vol.59
, pp. 388-393
-
-
Wang, H.1
Du, Y.2
Xiang, B.3
Lin, W.4
Wei, Q.5
-
24
-
-
84894403701
-
-
Moussay E, Palissot V, Vallar L, Poirel HA, Wenner T, et al. (2010) Research Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia.
-
(2010)
Research Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia
-
-
Moussay, E.1
Palissot, V.2
Vallar, L.3
Poirel, H.A.4
Wenner, T.5
-
26
-
-
0036791694
-
Low dose of resveratrol enhanced immune response of mice
-
Feng YH, Zhou WL, Wu QL, Li XY, Zhao WM, et al. (2002) Low dose of resveratrol enhanced immune response of mice. Acta Pharmacologica Sinica 23: 893-897.
-
(2002)
Acta Pharmacologica Sinica
, vol.23
, pp. 893-897
-
-
Feng, Y.H.1
Zhou, W.L.2
Wu, Q.L.3
Li, X.Y.4
Zhao, W.M.5
-
27
-
-
27744534829
-
(5 R)-5-hydroxytriptolide (LLDT-8), a novel triptolide analog mediates immunosuppressive effects in vitro and in vivo
-
Zhou R, Zhang F, He PL, Zhou WL, Wu QL, et al. (2005) (5 R)-5-hydroxytriptolide (LLDT-8), a novel triptolide analog mediates immunosuppressive effects in vitro and in vivo. International immunopharmacology 5: 1895-1903.
-
(2005)
International Immunopharmacology
, vol.5
, pp. 1895-1903
-
-
Zhou, R.1
Zhang, F.2
He, P.L.3
Zhou, W.L.4
Wu, Q.L.5
-
30
-
-
78149460388
-
A new xanthone from the bark extract of rheedia acuminata and antiplasmodial activity of its major compounds
-
Marti G, Eparvier V, Litaudon M, Grellier P, Guéritte F, (2010) A new xanthone from the bark extract of rheedia acuminata and antiplasmodial activity of its major compounds. Molecules 15: 7106-7114.
-
(2010)
Molecules
, vol.15
, pp. 7106-7114
-
-
Marti, G.1
Eparvier, V.2
Litaudon, M.3
Grellier, P.4
Guéritte, F.5
-
31
-
-
21144442100
-
An antibacterial biphenyl derivative from Garcinia bancana MIQ
-
Rukachaisirikul V, Naklue W, Sukpondma Y, Phongpaichit S, (2005) An antibacterial biphenyl derivative from Garcinia bancana MIQ. Chemical and pharmaceutical bulletin 53: 342-343.
-
(2005)
Chemical and Pharmaceutical Bulletin
, vol.53
, pp. 342-343
-
-
Rukachaisirikul, V.1
Naklue, W.2
Sukpondma, Y.3
Phongpaichit, S.4
-
32
-
-
0029993740
-
Antibacterial activity of some Garcinia benzophenone derivatives against methicillin-resistant Staphylococcus aureus
-
Iinuma M, Tosa H, Tanaka T, Kanamaru S, Asai F, et al. (1996) Antibacterial activity of some Garcinia benzophenone derivatives against methicillin-resistant Staphylococcus aureus. Biological & pharmaceutical bulletin 19: 311.
-
(1996)
Biological & Pharmaceutical Bulletin
, vol.19
, pp. 311
-
-
Iinuma, M.1
Tosa, H.2
Tanaka, T.3
Kanamaru, S.4
Asai, F.5
-
33
-
-
0346035902
-
Polyprenylated Benzophenones from Garcinia a ssigu and Their Potential Cancer Chemopreventive Activities
-
Ito C, Itoigawa M, Miyamoto Y, Onoda S, Rao KS, et al. (2003) Polyprenylated Benzophenones from Garcinia a ssigu and Their Potential Cancer Chemopreventive Activities. Journal of natural products 66: 206-209.
-
(2003)
Journal of Natural Products
, vol.66
, pp. 206-209
-
-
Ito, C.1
Itoigawa, M.2
Miyamoto, Y.3
Onoda, S.4
Rao, K.S.5
-
34
-
-
0642286438
-
Cytotoxic benzophenone derivatives from Garcinia species display a strong apoptosis-inducing effect against human leukemia cell lines
-
Matsumoto K, Akao Y, Kobayashi E, Ito T, Ohguchi K, et al. (2003) Cytotoxic benzophenone derivatives from Garcinia species display a strong apoptosis-inducing effect against human leukemia cell lines. Biological and Pharmaceutical Bulletin 26: 569-571.
-
(2003)
Biological and Pharmaceutical Bulletin
, vol.26
, pp. 569-571
-
-
Matsumoto, K.1
Akao, Y.2
Kobayashi, E.3
Ito, T.4
Ohguchi, K.5
-
35
-
-
34250308083
-
Specific inhibition of p300-HAT alters global gene expression and represses HIV replication
-
Mantelingu K, Reddy B, Swaminathan V, Kishore AH, Siddappa NB, et al. (2007) Specific inhibition of p300-HAT alters global gene expression and represses HIV replication. Chemistry & biology 14: 645-657.
-
(2007)
Chemistry & Biology
, vol.14
, pp. 645-657
-
-
Mantelingu, K.1
Reddy, B.2
Swaminathan, V.3
Kishore, A.H.4
Siddappa, N.B.5
-
38
-
-
84862816986
-
Icaritin inhibits T cell activation and prolongs skin allograft survival in mice
-
Li X, Hu Y, He L, Wang S, Zhou H, et al. (2012) Icaritin inhibits T cell activation and prolongs skin allograft survival in mice. International immunopharmacology.
-
(2012)
International Immunopharmacology
-
-
Li, X.1
Hu, Y.2
He, L.3
Wang, S.4
Zhou, H.5
-
39
-
-
27744476617
-
Immunomodulatory and therapeutic properties of the Nigella sativa L. seed
-
Salem ML, (2005) Immunomodulatory and therapeutic properties of the Nigella sativa L. seed. International immunopharmacology 5: 1749-1770.
-
(2005)
International Immunopharmacology
, vol.5
, pp. 1749-1770
-
-
Salem, M.L.1
-
40
-
-
3142588813
-
New immunosuppressants with potential implication in multiple sclerosis
-
Gonsette R, (2004) New immunosuppressants with potential implication in multiple sclerosis. Journal of the neurological sciences 223: 87-93.
-
(2004)
Journal of the Neurological Sciences
, vol.223
, pp. 87-93
-
-
Gonsette, R.1
-
42
-
-
0021740451
-
Cyclosporine: immunology, toxicity and pharmacology in experimental animals
-
Thomson A, Whiting P, Simpson J, (1984) Cyclosporine: immunology, toxicity and pharmacology in experimental animals. Inflammation Research 15: 306-327.
-
(1984)
Inflammation Research
, vol.15
, pp. 306-327
-
-
Thomson, A.1
Whiting, P.2
Simpson, J.3
-
43
-
-
20944443148
-
Organ transplantation-how much of the promise has been realized?
-
Lechler RI, Sykes M, Thomson AW, Turka LA, (2005) Organ transplantation-how much of the promise has been realized? Nature medicine 11: 605-613.
-
(2005)
Nature Medicine
, vol.11
, pp. 605-613
-
-
Lechler, R.I.1
Sykes, M.2
Thomson, A.W.3
Turka, L.A.4
-
44
-
-
84879041703
-
Immunosuppressants: A Review
-
Rathee P, Chaudhary H, Rathee S, Rathee D, Kumar V, (2012) Immunosuppressants: A Review. The Pharma Innovation- Journal 1: 90-101.
-
(2012)
The Pharma Innovation - Journal
, vol.1
, pp. 90-101
-
-
Rathee, P.1
Chaudhary, H.2
Rathee, S.3
Rathee, D.4
Kumar, V.5
|