Immunosuppressive activity on the murine immune responses of glycyrol from Glycyrrhiza uralensis via inhibition of calcineurin activity

Pharmaceutical Biology

Volumn 48, Issue 10, 2010, Pages 1177-1184

  Li, Jiayu ^a,b   Tu, Ying ^a   Tong, Li ^a   Zhang, Wen ^a   Zheng, Jianquan ^c   Wei, Qun ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

^b FUJIAN AGRICULTURE AND FORESTRY UNIVERSITY   (China)

^c BEIJING UNION UNIVERSITY   (China)

Author keywords

Calcineurin; Glycyrol; Immunosuppressive; Inhibit; T lymphocytes

Indexed keywords

CALCINEURIN; CONCANAVALIN A; GLYCYROL; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; GLYCYRRHIZA URALENSIS; GRAFT REJECTION; HUMAN; HUMAN CELL; IC 50; IMMUNE RESPONSE; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL LINE; LYMPHOCYTE PROLIFERATION; MALE; MAXIMUM TOLERATED DOSE; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN ALLOGRAFT; SPLEEN CELL; T LYMPHOCYTE;

ANIMALS; CALCINEURIN; CELL PROLIFERATION; CONCANAVALIN A; DOSE-RESPONSE RELATIONSHIP, DRUG; EARLY GROWTH RESPONSE PROTEIN 3; FLAVONOIDS; GLYCYRRHIZA URALENSIS; GRAFT SURVIVAL; HUMANS; HYPERSENSITIVITY, DELAYED; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-2; JURKAT CELLS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CULTURE TEST, MIXED; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NFATC TRANSCRIPTION FACTORS; PLANT EXTRACTS; PLANT ROOTS; SIGNAL TRANSDUCTION; SPLEEN; T-LYMPHOCYTES;

FABACEAE; GLYCYRRHIZA URALENSIS; MURINAE; MUS;

EID: 77957022665     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880200903573169     Document Type: Article

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