Evolution of the melanocortin-2 receptor in tetrapods: Studies on Xenopus tropicalis MC2R and Anolis carolinensis MC2R

General and Comparative Endocrinology

Volumn 188, Issue 1, 2013, Pages 75-84

  Davis, Perry ^a   Franquemont, Stephanie ^a   Liang, Liang ^a   Angleson, Joseph K ^a   Dores, Robert M ^a  

^a UNIVERSITY OF DENVER   (United States)

Author keywords

ACTH; Amphibian; Constructive neutral evolution; Evolutionary cell biology; Melanocortin 2 receptor; Reptile

Indexed keywords

ALANINE; LIGAND; MELANOCORTIN 2 RECEPTOR; MELANOCORTIN 2 RECEPTOR ACCESSORY PROTEIN 1; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; AMPHIBIA; ANOLIS CAROLINENSIS; ANURA; BINDING SITE; CARBOXY TERMINAL SEQUENCE; EVOLUTION; GALLUS GALLUS; GENE; GENE FUNCTION; GENE STRUCTURE; GENETIC ANALYSIS; HUMAN; MAMMAL; MC2R GENE; MRAP1 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REPTILE; REVIEW; TETRAPOD; XENOPUS TROPICALIS;

EID: 84878995561     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1016/j.ygcen.2013.04.007     Document Type: Review

References (48)

1. Agulleiro M.J., Roy S., Sanchez E., Puchol S., Gallo-Payet N., Cerda-Reverter J.M. Role of melanocortin receptor accessory proteins in the function of zebrafish melanocortin receptor type 2. Mol. Cell. Endocrinol. 2010, 320:145-152.
2. Baker B. The evolution of ACTH, MSH, and LPH-structure, function, and development. Horm. Evol. 1980, 2:643-722.
3. Bentley P.J. Comparative Vertebrate Endocrinology 1998, Cambridge University Press, Cambridge. third ed.
4. Bhullar B.A.S., Marugán-Lobón J.S., Racimo F., Bever G.S., Rowe T.B., Norell M.A., Abzhanov A. Birds have paedomorphic dinosaur skulls. Nature 2012, 487:223-226.
5. Buckley D.I., Ramachandran J. Characterization of corticotropin receptors on adrenocortical cells. Proc. Natl. Acad. Sci. USA 1981, 78:7431-7435.
6. Carroll R.L. Vertebrate Paleontology and Evolution 1988, W.H. Freeman Press, New York.
7. Cheng H.H. Mapping the chicken genome. Poult. Sci. 1997, 76:1101-1107.
8. Chepurny O.G., Holz G.G. A novel cyclic adenosine monophosphate responsive luciferase reporter incorporating a nonpalindromic cyclic adenosine monophosphate response element provides optimal performance for use in G protein coupled receptor drug discovery efforts. J. Biomol. Screen. 2007, 12:740-746.
9. Chung T.T., Webb T.R., Chan L.F., Cooray S.N., Metherell L.A., King P.J., Chapple J.P., Clark A.J.L. The majority of ACTH receptor (MC2R) mutations found in familial glucocorticoid deficiency type 1 lead to defective trafficking of the receptor to the cell surface. J. Clin. Endocrinol. Metab. 2008, 93:4948-4954.
10. Clark A.J.L., McLoughlin L., Grossman A. Familial glucocorticoid deficiency associated with point mutation in the adrenocorticotropin receptor. Lancet 1993, 341:461-462.
11. Cone R.D. Studies on the physiological functions of the melanocortin system. Endocr. Rev. 2006, 27:736-749.
12. Costa J.L., Bui S., Reed P., Dores R.M., Hochgeschwender U., Brennan M.B. Mutational analysis of evolutionarily conserved ACTH residues. Gen. Comp. Endocrinol. 2004, 136:12-16.
13. Dores R.M. ACTH, the MSHs and the melanocortin receptors: revisiting the work of Robert Schwyzer - a 30year retrospective. Ann. NY Acad. Sci. 2009, 1163:93-100.
14. Dores R.M., Rubin D.A., Quinn T.W. Mini-review: is it possible to construct phylogenetic trees using polypeptide hormone sequences. Gen. Comp. Endocrinol. 1996, 103:1-12.
15. Dores R.M., Baron A.J. Evolution of POMC: origin, phylogeny, posttranslational processing, and the melanocortins. Ann. NY Acad. Sci. 2011, 1220:34-48.
16. Duellman W.E., Trueb L. The Biology of Amphibians 1986, 417-437. Johns Hopkins Press, Baltimore.
17. Eberle A., Schwyzer R. Hormone-receptor interactions. Demonstration of the two message sequences (active sites) in α-melanocotropin. Helv. Chim. Acta 1975, 58:1528-1535.
18. Eipper B.A., Mains R.E. Structure and biosynthesis of pro- adrenocorticotropin/endorphin and related peptides. Endocr. Rev. 1980, 1:1-27.
19. Engelmann M., Landgraf R., Wotjak C. The hypothalamic-neurohypophysial system regulates the hypothalamic-pituitary-adrenal axis under stress: an old concept revisited". Front. Neuroendocrinol. 2004, 25:132-149.
20. Forti F.L., Dias M.H.S., Armelin H.A. ACTH receptor: ectopic expression, activity and signaling. Mol. Cell. Biochem. 2006, 293:147-160.
21. Gantz I., Fong T.M. The melanocortin system. Am. J. Physiol. Endocrinol. Metab. 2003, 284:E468-E474.
22. Haitina T., Klovins J., Takahashi A., Löwgren M., Ringholm A., Enberg J., Kawauchi H., Larson E.T., Fredriksson R., Schiöth H.B. Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes. BMC Evol. Biol. 2007, 7:101-115.
23. Hinkle P.M., Sebag J.A. Structure and function of the melanocortin 2 receptor accessory protein. Mol. Cell. Endocrinol. 2009, 300:25-31.
24. Kemp T.S. The origin and early radiation of the therapsid mammal-like reptiles: a palaeobiological hypothesis. J. Evol. Biol. 2006, 19:1231-1247.
25. Kilianova Z., Basora N., Kilian P., Payet M.D., Gallo-Payet N. Human menaocortin receptor 2 expression and functionality: effects of protein kinase A and protein kinase C on desensitization and internalization. Endocrinology 2006, 147:2325-2337.
26. Klovins J., Haitina T., Ringholm A., Lowgren M., Fridmanis D., Slaidina M., Stier S., Schiöth H.B. Cloning of two melanocortin (MC) receptors in spiny dogfish. Eur. J. Biochem. 2004, 271:4320-4331.
27. Li C.H., Geschwind I.I., Cole R.D., Raake I.D., Harris J.I., Dixon J.S. Amino-acid sequence of alpha-corticotrophin. Nature 1955, 176:687-689.
28. Liang L., Sebag J.A., Eagelston L., Serasinghe M.N., Veo K., Reinick C., Angleson J., Hinkle P.M., Dores R.M. Functional expression of frog and rainbow trout melanocortin 2 receptors using heterologous MRAP1s. Gen. Comp. Endocrinol. 2011, 174:5-14.
29. Liang L., Angleson J.K., Dores R.M. Review: using the human melanocortin-2 receptor as a model for analyzing hormone/receptor interactions between a mammalian MC2 receptor and ACTH(1-24). Gen. Comp. Endocrinol. 2013, http://dx.doi.org/10.11016/j.ygcen.2012.11.011.
30. Ling M.K., Hotta E., Kilanova Z., Haitina T., Ringholm A., Johansson L., Gallo-Payet N., Takeuchi S., Schhioth H.N. The melanocortin receptor subtypes in chicken have high preference to ACTH-derived peptides. Br. J. Pharm. 2004, 143:626-637.
31. Metherell L.A., Chapple J.P., Cooray S., David A., Becker C., Ruschendorf F., Naville D., Begeot M., Khoo B., Nurnberg P., Huebner A., Cheethan M.E., Clark A.J. Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2. Nat. Genet. 2005, 37:166-170.
32. Mountjoy K.G., Robbins L.S., Mortrud M.T., Cone R.D. The cloning of a family of genes that encode the melanocortin receptors. Science 1992, 257:1248-1251.
33. Nakanishi S., Inoue A., Kita T., Nakamura M., Chung A.C.Y., Cohen S.N., Numa S. Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor. Nature 1979, 278:423-427.
34. Nelson J.S. Fishes of the World 1994, Wiley Press, New York. third ed.
35. Panchen A.L., Smithson T.R. The relationship of the earliest tetrapods. The Phylogeny and Classification of the Tetrapods, Volume 1: Amphibians, Reptiles, and Birds, The Systematics Association Special Volume NO 35A 1988, 1-32. Clarendon Press, Oxford. M.J. Benton (Ed.).
36. Pogozheva I.D., Chai B.-X., Lomize A.L., Fong T.M., Weinberg D.H., Nargund R.P., Mulholland M.W., Grantz I., Mosberg H.I. Interactions of human melanocortin 4 receptors with nonpeptide and peptide agonists. Biochemistry 2005, 44:11329-11341.
37. Rachel M., El Mourabit H., Buronfosse A., Blondet A., Naville D., Begeot M., Penhoat A. Expression of the human melanocortin-2 receptor in different eukaryotic cells. Peptides 2005, 26:1842-1847.
38. Reinick C.L., Liang L., Angleson J.K., Dores R.M. Functional expression of Squalus acanthias melanocortin 5 Receptor in CHO Cells, ligand selectivity and interaction with MRAP. Eur. J. Pharm. 2012, 680:1-7.
39. Reinick C.L., Liang L., Angleson J.K., Dores R.M. Identification of an MRAP-independent melanocortin-2 receptor: functional expression of the cartilaginous fish, Callorhinchus milii, melanocortin-2 receptor in CHO cells. Endocrinology 2012, 153:4757-4765.
40. Ringholm A., Klovins J., Fredriksson R., Poliakova N., Larson E.T., Kukkonen J.P., Larhammar D., Schiöth H.D. Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin system. Eur. J. Biochem. 2003, 270:213-221.
41. Roy S., Rachel M., Gallo-Payet N. Differential regulation of the human adrenocorticotropin receptor [melanocortin-2 receptor (MC2R)] by human MC2R accessory protein isoforms α and β in isogenic human embryonic kidney 293 cells. Mol. Endocrinol. 2007, 21:1656-1669.
42. Sahney S., Benton M.J., Ferry P.A. Links between global taxonomic diversity, ecological diversity, and expansion of vertebrates on land. Biol. Lett. 2010, 6:544-547.
43. Schwyzer R. ACTH: a short introductory review. Ann. NY Acad. Sci. 1977, 297:3-26.
44. Sebag J.A., Hinkle P.M. Melanocortin-2 receptor accessory protein MRAP forms antiparallel homodimers. Proc. Natl. Acad. Sci. USA 2007, 104:20244-20249.
45. Sebag J.A., Hinkle P.M. Regions of melanocortin w (MC2) receptor accessory protein necessary for duel topology and MC2 receptor trafficking and signaling. J. Biol. Chem. 2009, 284:610-618.
46. Stolzfus A. On the possibility of constructive neutral evolution. J. Mol. Evol. 1999, 49:169-181.
47. Vastermark A., Schiöth H.B. The early origin of melanocortin receptors, agouti-related peptide, agouti signaling peptide, and melanocortin receptor-accessory proteins, with emphasis on pufferfishes, elephant shark, lampreys, and amphioxus. Eur. J. Pharmacol. 2011, 10.1016/j.ejphar.2010.10.106.
48. Webb T.R., Clark J.L. Minireview: the melanocortin 2 receptor accessory proteins. Mol. Endocrinol. 2010, 24:475-484.