Progression of genotype-specific oral cancer leads to senescence of cancer-associated fibroblasts and is mediated by oxidative stress and TGF-β

Carcinogenesis

Volumn 34, Issue 6, 2013, Pages 1286-1295

  Hassona, Yazan ^a   Cirillo, Nicola ^a,b   Lim, Kue Peng ^a,c   Herman, Andrew ^a   Mellone, Max ^d   Thomas, Gareth J ^d   Pitiyage, Gayani N ^e   Ken Parkinson, E ^e   Prime, Stephen S ^a,e  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c CANCER RESEARCH INITIATIVES FOUNDATION   (Malaysia)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2;

ARTICLE; CANCER GROWTH; CONTROLLED STUDY; DNA DAMAGE; FIBROBLAST; GENETICALLY UNSTABLE ORAL SQUAMOUS CELL CARCINOMA; GENOTYPE; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; MOUTH SQUAMOUS CELL CARCINOMA; OXIDATIVE STRESS; PRIORITY JOURNAL; SENESCENCE;

ANTIOXIDANTS; BETA-GALACTOSIDASE; CARCINOMA, SQUAMOUS CELL; CELL AGING; CELL LINE, TUMOR; CULTURE MEDIA, CONDITIONED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DISEASE PROGRESSION; DNA DAMAGE; FIBROBLASTS; GENOTYPE; HUMANS; HYDROGEN PEROXIDE; KERATINOCYTES; MOUTH MUCOSA; MOUTH NEOPLASMS; OXIDANTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84878986001     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgt035     Document Type: Article

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