Gene expression of IL17 and IL23 in the lungs of patients with active tuberculosis

Thorax

Volumn 63, Issue 6, 2008, Pages 566-568

  Dheda, K ^a,b   Chang, J S ^a   Lala, S ^b   Huggett, J F ^a   Zumla, A ^a   Rook, G A W ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 4; MESSENGER RNA; RNA; TRANSFORMING GROWTH FACTOR BETA;

ANALYTICAL PARAMETERS; BRONCHOSCOPY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COMPARTMENTALIZATION; CELL ISOLATION; CELL LINEAGE; CYTOKINE PRODUCTION; GENE EXPRESSION; GENE EXPRESSION PROFILING; HELPER CELL; HUMAN; IMMUNOPATHOGENESIS; LETTER; LUNG LAVAGE; LUNG TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BRONCHOALVEOLAR LAVAGE FLUID; GENE EXPRESSION; HUMANS; INTERFERON TYPE II; INTERLEUKIN-17; INTERLEUKIN-23; INTERLEUKIN-4; TUBERCULOSIS, PULMONARY;

EID: 45149086964     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.2007.092205     Document Type: Letter

References (5)

1. Dheda K, Chang J-S, Breen RA, et al. In vivo and in vitro studies of a novel cytokine, interleukin-4delta2, in pulmonary tuberculosis. Am J Respir Crit Care Med 2005;172:501-8.
2. Stockinger B, Veldhoen M. Differentiation and function of Th17 T cells. Curr Opin Immunol 2007;19:281-6.
3. Lockhart E, Green AM, Flynn JL. IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection. J Immunol 2006;177:4662-9.
4. Umemura M, Yahagi A, Hamada S, et al. IL-17-mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis bacille Calmette-Guerin infection. J Immunol 2007;178:3786-96.
5. Chen Z, Tato CM, Muul L, et al. Distinct regulation of interleukin-17 in human T helper lymphocytes. Arthritis Rheum 2007;56:2936-46.