Induction of granulysin and perforin cytolytic mediator expression in 10-week-old infants vaccinated with BCG at birth

Clinical and Developmental Immunology

Volumn 2011, Issue , 2011, Pages

  Ress, Stanley ^a,f   Semple, Patricia L ^a   Watkins, Marcia ^a,b   Davids, Virginia ^c   Krensky, Alan M ^d   Hanekom, Willem A ^a,c   Kaplan, Gilla ^e  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b NATIONAL HEALTH LABORATORY SERVICE   (South Africa)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

^d NATIONAL CANCER INSTITUTE   (United States)

^e PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

^f UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; CD56 ANTIGEN; GRANULYSIN; PERFORIN; TUBERCULIN; GNLY PROTEIN, HUMAN; T LYMPHOCYTE ANTIGEN;

ADULT; ARTICLE; BACTERICIDAL ACTIVITY; BCG VACCINATION; BLOOD; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; HUMAN; HUMAN EXPERIMENT; INFANT; MALE; MYCOBACTERIUM TUBERCULOSIS; NATURAL KILLER CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUBERCULOSIS; UMBILICAL CORD BLOOD; UPREGULATION; BIOSYNTHESIS; FETUS BLOOD; IMMUNOLOGY; METABOLISM; MIDDLE AGED; MYCOBACTERIUM BOVIS; VACCINATION;

ADULT; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BCG VACCINE; FEMALE; FETAL BLOOD; HUMANS; INFANT; KILLER CELLS, NATURAL; MALE; MIDDLE AGED; MYCOBACTERIUM BOVIS; PERFORIN; T-LYMPHOCYTES, CYTOTOXIC; TUBERCULOSIS; UP-REGULATION; VACCINATION; YOUNG ADULT;

EID: 79952212672     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2011/438463     Document Type: Article

References (53)

1. WHO, Global Atlas of Infectious Diseases 2007 Geneva, Switzerland World Health Organisation
2. Colditz G. A., Berkey C. S., Mosteller F., Brewer T. F., Wilson M. E., Burdick E., Fineberg H. V., The efficacy of bacillus Calmette-Guerin vaccination of newborns and infants in the prevention of tuberculosis: meta-analyses of the published literature Pediatrics 1995 96 1 29 35
3. Fine P., Reichman L., Hirschfield E. S., BCG vaccines and vaccination Tuberculosis 2007
4. Stensballe L. G., Nante E., Jensen I. P., Kofoed P.-E., Poulsen A., Jensen H., Newport M., Marchant A., Aaby P., Acute lower respiratory tract infections and respiratory syncytial virus in infants in Guinea-Bissau: a beneficial effect (Pubitemid 40126528)
5. Al Jarad N., Empey D. W., Duckworth G., Administration of the BCG vaccination using the multipuncture method in schoolchildren: a comparison with the intradermal method Thorax 1999 54 9 762 764 (Pubitemid 29401537)
6. Hart P. D., Efficacy and applicability of mass B. C.G. vaccination in tuberculosis control British Medical Journal 1967 1 540 587 592
7. Kemp E. B., Belshe R. B., Hoft D. F., Immune responses stimulated by percutaneous and intradermal bacille Calmette-Guerin Journal of Infectious Diseases 1996 174 1 113 119 (Pubitemid 26255562)
8. Ormerod L. P., Palmer C., Tuberculin reactivity after neonatal percutaneous BCG immunisation Archives of Disease in Childhood 1993 69 1 155 (Pubitemid 23233014)
9. Davids V., Hanekom W. A., Mansoor N., Gamieldien H., Gelderbloem S. J., Hawkridge A., Hussey G. D., Hughes E. J., Soler J., Murray R. A., Ress S. R., Kaplan G., The effect of bacille Calmette-Gurin vaccine strain and route of administration on induced immune responses in vaccinated infants Journal of Infectious Diseases 2006 193 4 531 536 (Pubitemid 43202744)
10. Khanna M., Srivastava L. M., Kumar P., Defective interleukin-2 production and interleukin-2 receptor expression in pulmonary tuberculosis Journal of Communicable Diseases 2003 35 2 65 70 (Pubitemid 39164102)
11. Kaufmann S. H. E., Andersen P., Immunity to mycobacteria with emphasis on tuberculosis: implications for rational design of an effective tuberculosis vaccine Chemical Immunology 1998 70 21 59 (Pubitemid 28059685)
12. Stenger S., Modlin R. L., T cell mediated immunity to Mycobacterium tuberculosis Current Opinion in Microbiology 1999 2 1 89 93 (Pubitemid 29130221)
13. Adkins B., Leclerc C., Marshall-Clarke S., Neonatal adaptive immunity comes of age Nature Reviews Immunology 2004 4 7 553 564 (Pubitemid 38931770)
14. Harris D. T., Schumacher M. J., Locascio J., Besencon F. J., Olson G. B., DeLuca D., Shenker L., Bard J., Boyse E. A., Phenotypic and functional immaturity of human umbilical cord blood T lymphocytes Proceedings of the National Academy of Sciences of the United States of America 1992 89 21 10006 10010
15. Suen Y., Lee S. M., Qian J., Van De Ven C., Cairo M. S., Dysregulation of lymphokine production in the neonate and its impact on neonatal cell mediated immunity Vaccine 1998 16 14-15 1369 1377 (Pubitemid 28364670)
16. Trivedi H. N., Hayglass K. T., Gangur V., Allardice J. G., Embree J. E., Plummer F. A., Analysis of neonatal T cell and antigen presenting cell functions Human Immunology 1997 57 2 69 79 (Pubitemid 28020904)
17. Elias D., Akuffo H., Britton S., PPD induced in vitro interferon gamma production is not a reliable correlate of protection against Mycobacterium tuberculosis Transactions of the Royal Society of Tropical Medicine and Hygiene 2005 99 5 363 368 (Pubitemid 40361566)
18. Mittrcker H.-W., Steinhoff U., Khler A., Krause M., Lazar D., Mex P., Miekley D., Kaufmann S. H. E., Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis Proceedings of the National Academy of Sciences of the United States of America 2007 104 30 12434 12439 (Pubitemid 47206155)
19. Stenger S., Hanson D. A., Teitelbaum R., Dewan P., Niazi K. R., Froelich C. J., Ganz T., Thoma-Uszynski S., Melin A., Bogdan C., Porcelli S. A., Bloom B. R., Krensky A. M., Modlin R. L., An antimicrobial activity of cytolytic T cells mediated by granulysin Science 1998 282 5386 121 125 (Pubitemid 28471143)
20. Ridings J., Weedon H., Ioannou C., Flego L., Macardle P. J., Zola H., Purification of cord blood lymphocytes Journal of Immunological Methods 1996 195 1-2 43 48 (Pubitemid 26292686)
21. Pea S. V., Hanson D. A., Carr B. A., Goralski T. J., Krensky A. M., Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins Journal of Immunology 1997 158 6 2680 2688 (Pubitemid 127470525)
22. Gansert J. L., Kieler V., Engele M., Wittke F., Rllinghoff M., Krensky A. M., Porcelli S. A., Modlin R. L., Stenger S., Human NKT cells express granulysin and exhibit antimycobacterial activity Journal of Immunology 2003 170 6 3154 3161 (Pubitemid 36302192)
23. + T cells kill intracellular Mycobacterium tuberculosis by a perforin and Fas/Fas ligand-independent mechanism Journal of Immunology 2001 167 5 2734 2742 (Pubitemid 32768904)
24. Berthou C., Legros-Maida S., Soulie A., Wargnier A., Guillet J., Rabian C., Gluckman E., Sasportes M., Cord blood T lymphocytes lack constitutive perforin expression in contrast to adult peripheral blood T lymphocytes Blood 1995 85 6 1540 1546
25. Agarwal R., Loganath A., Roy A. C., Wong Y. C., Ng S. C., Expression profiles of interleukin-15 in early and late gestational human placenta and in pre-eclamptic placenta Molecular Human Reproduction 2001 7 1 97 101 (Pubitemid 32101770)
26. Sable S. B., Kaur S., Verma I., Khuller G. K., Immunodominance of low molecular weight secretory polypeptides of Mycobacterium tuberculosis to induce cytotoxic T-lymphocyte response Vaccine 2005 23 41 4947 4954 (Pubitemid 41242872)
27. Santosuosso M., Zhang X., McCormick S., Wang J., Hitt M., Xing Z., Mechanisms of mucosal and parenteral tuberculosis vaccinations: adenoviral-based mucosal immunization preferentially elicits sustained accumulation of immune protective CD4 and CD8 T cells within the airway lumen Journal of Immunology 2005 174 12 7986 7994 (Pubitemid 40806309)
28. + T cells in human tuberculosis Proceedings of the National Academy of Sciences of the United States of America 2000 97 22 12210 12215
29. Hussey G. D., Watkins M. L. V., Goddard E. A., Gottschalk S., Hughes E. J., Iloni K., Kibel M. A., Ress S. R., Neonatal mycobacterial specific cytotoxic T-lymphocyte and cytokine profiles in response to distinct BCG vaccination strategies Immunology 2002 105 3 314 324 (Pubitemid 34304408)
30. + T cells Journal of Experimental Medicine 2004 199 7 925 936 (Pubitemid 38481084)
31. Murray R. A., Mansoor N., Harbacheuski R., Soler J., Davids V., Soares A., Hawkridge A., Hussey G. D., Maecker H., Kaplan G., Hanekom W. A., Bacillus Calmette Guerin vaccination of human newborns induces a specific, functional CD8+ T cell response Journal of Immunology 2006 177 8 5647 5651 (Pubitemid 44527640)
32. Capinos Scherer C. F., Endsley J. J., De Aguiar J. B., Jacobs W. R. Jr., Larsen M. H., Palmer M. V., Nonnecke B. J., Ray Waters W., Mark Estes D., Evaluation of granulysin and perforin as candidate biomarkers for protection following vaccination with mycobacterium bovis BCG or M. bovisRD1 Transboundary and Emerging Diseases 2009 56 6-7 228 239
33. Mardi L., Innate cellular immune responses in newborns Clinical Immunology 2006 118 2-3 137 144
34. Watkins M. L. V., Semple P. L., Abel B., Hanekom W. A., Kaplan G., Ress S. R., Exposure of cord blood to Mycobacterium bovis BCG induces an innate response but not a T-cell cytokine response Clinical and Vaccine Immunology 2008 15 11 1666 1673
35. White G. P., Watt P. M., Holt B. J., Holt P. G., Differential patterns of methylation of the IFN- promoter at CpG and non-CpG sites underlie differences in IFN- gene expression between human neonatal and adult CD45RO- T cells Journal of Immunology 2002 168 6 2820 2827 (Pubitemid 34211661)
36. Endsley J. J., Endsley M. A., Mark Estes D., Bovine natural killer cells acquire cytotoxic/effector activity following activation with IL-12/15 and reduce Mycobacterium bovis BCG in infected macrophages Journal of Leukocyte Biology 2006 79 1 71 79 (Pubitemid 43054251)
37. Dieli F., Sireci G., Caccamo N., Di Sano C., Titone L., Romano A., Di Carlo P., Barera A., Accardo-Palumbo A., Krensky A. M., Salerno A., Selective depression of interferon- and granulysin production with increase of proliferative response by V 9/V 2 T cells in children with tuberculosis Journal of Infectious Diseases 2002 186 12 1835 1839 (Pubitemid 35469162)
38. Sahiratmadja E., Alisjahbana B., Buccheri S., Di Liberto D., de Boer T., Adnan I., van Crevel R., Klein M. R., van Meijgaarden K. E., Nelwan R. H. H., van de Vosse E., Dieli F., Ottenhoff T. H. M., Plasma granulysin levels and cellular interferon- production correlate with curative host responses in tuberculosis, while plasma interferon- levels correlate with tuberculosis disease activity in adults Tuberculosis 2007 87 4 312 321 (Pubitemid 46936241)
39. Van Rie A., Madhi S. A., Heera J. R., Meddows-Taylor S., Wendelboe A. M., Anthony F., Violari A., Tiemessen C. T., Gamma interferon production in response to Mycobacterium bovis BCG and Mycobacterium tuberculosis antigens in infants born to human immunodeficiency virus-infected mothers Clinical and Vaccine Immunology 2006 13 2 246 252 (Pubitemid 43383794)
40. Endsley J. J., Hogg A., Shell L. J., McAulay M., Coffey T., Howard C., Capinos Scherer C. F., Waters W. R., Nonnecke B., Estes D. M., Villarreal-Ramos B., Mycobacterium bovis BCG vaccination induces memory CD4+ T cells characterized by effector biomarker expression and anti-mycobacterial activity Vaccine 2007 25 50 8384 8394 (Pubitemid 350137604)
41. + T cells use granulysin to kill Cryptococcus neoformans, and activation of this pathway is defective in HIV patients Blood 2007 109 5 2049 2057 (Pubitemid 46348205)
42. Ochoa M.-T., Stenger S., Sieling P. A., Thoma-Uszynski S., Sabet S., Cho S., Krensky A. M., Rollinghoff M., Nunes Sarno E., Burdick A. E., Rea T. H., Modlin R. L., T-cell release of granulysin contributes to host defense in leprosy Nature Medicine 2001 7 2 174 179 (Pubitemid 32148483)
43. Andersson J., Samarina A., Fink J., Rahman S., Grundstrm S., Impaired expression of perforin and granulysin in CD8+ T cells at the site of infection in human chronic pulmonary tuberculosis Infection and Immunity 2007 75 11 5210 5222 (Pubitemid 350033607)
44. Tsunetsugu-Yokota Y., Tamura H., Tachibana M., Ogata K., Honda M., Takemori T., Selective expansion of perforin-positive CD8+ T cells by immature dendritic cells infected with live Bacillus Calmette-Gurin mycobacteria Journal of Leukocyte Biology 2002 72 1 115 124
45. Ma L. L., Spurrell J. C. L., Wang J. F., Neely G. G., Epelman S., Krensky A. M., Mody C. H., CD8 T cell-mediated killing of Cryptococcus neoformans requires granulysin and is dependent on CD4 T cells and IL-15 Journal of Immunology 2002 169 10 5787 5795 (Pubitemid 35291681)
46. Leonard W. J., Spolski R., Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation Nature Reviews Immunology 2005 5 9 688 698 (Pubitemid 43086171)
47. Rook G. A. W., Lowrie D. B., Hernndez-Pando R., Immunotherapeutics for tuberculosis in experimental animals: is there a common pathway activated by effective protocols? Journal of Infectious Diseases 2007 196 2 191 198 (Pubitemid 47047457)
48. Marchant A., Goetghebuer T., Ota M. O., Wolfe I., Ceesay S. J., De Groote D., Corrah T., Bennett S., Wheeler J., Huygen K., Aaby P., McAdam K. P. W. J., Newport M. J., Newborns develop a Th1-type immune response to Mycobacterium bovis bacillus Calmette-Guerin vaccination Journal of Immunology 1999 163 4 2249 2255 (Pubitemid 29382234)
49. Doherty T. M., Rook G., Progress and hindrances in tuberculosis vaccine development The Lancet 2006 367 9514 947 949
50. Rook G. A. W., Hernandez-Pando R., Dheda K., Teng Seah G., IL-4 in tuberculosis: implications for vaccine design Trends in Immunology 2004 25 9 483 488 (Pubitemid 39490255)
51. Ahlers J. D., Belyakov I. M., Memories that last forever: strategies for optimizing vaccine T-cell memory Blood 2010 115 9 1678 1689
52. Sterne J. A. C., Rodrigues L. C., Guedes I. N., Does the efficacy of BCG decline with time since vaccination? International Journal of Tuberculosis and Lung Disease 1998 2 3 200 207 (Pubitemid 28123518)
53. Behr M. A., Correlation between BCG genomics and protective efficacy Scandinavian Journal of Infectious Diseases 2001 33 4 249 252 (Pubitemid 32366647