ATRA and the specific RARα agonist, NRX195183, have opposing effects on the clonogenicity of pre-leukemic murine AML1-ETO bone marrow cells

Leukemia

Volumn 27, Issue 6, 2013, Pages 1369-1380

  Chee, L C Y ^a,b,c   Hendy, J ^a,d   Purton, L E ^b,d   McArthur, G A ^a,b  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

^d ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

AML1 ETO; myeloid differentiation; RARa; RARg; retinoids

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; NRX 195183; NRX 204723; PROTEIN KINASE B; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETINOID; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL MATURATION; CELL RENEWAL; CELL STRUCTURE; CLONOGENESIS; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRELEUKEMIA; PRIORITY JOURNAL; UPREGULATION;

ANIMALS; CORE BINDING FACTOR ALPHA 2 SUBUNIT; FLOW CYTOMETRY; MICE; MICE, INBRED C57BL; ONCOGENE PROTEINS, FUSION; RECEPTORS, RETINOIC ACID; TRETINOIN;

EID: 84878946742     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2012.362     Document Type: Article

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