메뉴 건너뛰기




Volumn 50, Issue 3, 2013, Pages 600-607

PACAP protects against salsolinol-induced toxicity in dopaminergic SH-SY5Y cells: Implication for Parkinson's disease

Author keywords

Apoptosis; BDNF; Neuroprotection; p CREB; PACAP; Salsolinol; SH SY5Y cell line

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; SALSOLINOL; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2;

EID: 84878930078     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-0015-7     Document Type: Article
Times cited : (54)

References (53)
  • 1
    • 84857063922 scopus 로고    scopus 로고
    • Cyclic AMP response element-binding protein (CREB) phosphorylation: A mechanistic marker in the development of memory enhancing Alzheimer's disease therapeutics
    • 10.1016/j.bcp.2011.11.009
    • Bitner S (2012) Cyclic AMP response element-binding protein (CREB) phosphorylation: a mechanistic marker in the development of memory enhancing Alzheimer's disease therapeutics. Biochem Pharmacol 83:705-714
    • (2012) Biochem Pharmacol , vol.83 , pp. 705-714
    • Bitner, S.1
  • 2
    • 33746062079 scopus 로고    scopus 로고
    • TRPC1 protects human SH-SY5Y cells against salsolinol-induced cytotoxicity by inhibiting apoptosis
    • 16765919 10.1016/j.brainres.2006.04.104 1:CAS:528:DC%2BD28XntlWitLw%3D
    • Bollimuntha S, Ebadi M, Singh BB (2006) TRPC1 protects human SH-SY5Y cells against salsolinol-induced cytotoxicity by inhibiting apoptosis. Brain Res 1099:141-149
    • (2006) Brain Res , vol.1099 , pp. 141-149
    • Bollimuntha, S.1    Ebadi, M.2    Singh, B.B.3
  • 3
    • 79951957765 scopus 로고    scopus 로고
    • Neuroprotective effects of PACAP against ethanol-induced toxicity in the developing rat cerebellum
    • 20422475 10.1007/s12640-010-9186-y 1:CAS:528:DC%2BC3MXltVGrs7Y%3D
    • Botia B, Jolivel V, Burel D et al (2011) Neuroprotective effects of PACAP against ethanol-induced toxicity in the developing rat cerebellum. Neurotox Res 19:423-434
    • (2011) Neurotox Res , vol.19 , pp. 423-434
    • Botia, B.1    Jolivel, V.2    Burel, D.3
  • 4
    • 34548635103 scopus 로고    scopus 로고
    • Antiapoptotic effects of nicotine in its protection against salsolinol-induced cytotoxicity
    • 17513200 10.1007/BF03033901 1:CAS:528:DC%2BD2sXhtVSiu7fP
    • Copeland RL, Das JR, Kanaan YM (2007) Antiapoptotic effects of nicotine in its protection against salsolinol-induced cytotoxicity. Neurotox Res 12:61-69
    • (2007) Neurotox Res , vol.12 , pp. 61-69
    • Copeland, R.L.1    Das, J.R.2    Kanaan, Y.M.3
  • 5
    • 70349898590 scopus 로고    scopus 로고
    • Additive protective effects of donepezil and nicotine against salsolinol-induced cytotoxicity in SH-SY5Y cells
    • 19526284 10.1007/s12640-009-9040-2 1:CAS:528:DC%2BD1MXhtFOkt7nK
    • Das JR, Tizabi Y (2009) Additive protective effects of donepezil and nicotine against salsolinol-induced cytotoxicity in SH-SY5Y cells. Neurotox Res 16:194-204
    • (2009) Neurotox Res , vol.16 , pp. 194-204
    • Das, J.R.1    Tizabi, Y.2
  • 6
    • 22744432325 scopus 로고    scopus 로고
    • Neuroprotective potential of three neuropeptides PACAP, VIP and PHI
    • 15985713 1:CAS:528:DC%2BD2MXhtVClurnK
    • Dejda A, Sokolowska P, Nowak JZ (2005) Neuroprotective potential of three neuropeptides PACAP, VIP and PHI. Pharmacol Rep 57:307-320
    • (2005) Pharmacol Rep , vol.57 , pp. 307-320
    • Dejda, A.1    Sokolowska, P.2    Nowak, J.Z.3
  • 7
    • 59149103611 scopus 로고    scopus 로고
    • Isolation of peptide transport system-6 from brain endothelial cells: Therapeutic effects with antisense inhibition in Alzheimer and stroke models
    • 19002200 10.1038/jcbfm.2008.131 1:CAS:528:DC%2BD1MXhtFOrtbo%3D
    • Dogrukol-Ak D, Kumar VB, Ryerse JS, Farr SA, Verma S, Nonaka N (2009) Isolation of peptide transport system-6 from brain endothelial cells: therapeutic effects with antisense inhibition in Alzheimer and stroke models. J Cereb Blood Flow Metab 29:411-422
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 411-422
    • Dogrukol-Ak, D.1    Kumar, V.B.2    Ryerse, J.S.3    Farr, S.A.4    Verma, S.5    Nonaka, N.6
  • 8
    • 84859259397 scopus 로고    scopus 로고
    • Updates in the medical management of Parkinson disease
    • 22219231 10.3949/ccjm.78gr.11005
    • Fernandez HH (2012) Updates in the medical management of Parkinson disease. Cleve Clin J Med 79:28-35
    • (2012) Cleve Clin J Med , vol.79 , pp. 28-35
    • Fernandez, H.H.1
  • 9
    • 0035901719 scopus 로고    scopus 로고
    • BDNF mediates the neuroprotective effect of PACAP-38 on rat cortical neurons
    • 11303760 10.1097/00001756-200104170-00011 1:CAS:528:DC%2BD3MXjtVWhu7o%3D
    • Frechilla D, Garcia-Osta A, Palacios S, Cenarruzabebeitia E, Del Rio J (2001) BDNF mediates the neuroprotective effect of PACAP-38 on rat cortical neurons. Neuroreport 12:919-923
    • (2001) Neuroreport , vol.12 , pp. 919-923
    • Frechilla, D.1    Garcia-Osta, A.2    Palacios, S.3    Cenarruzabebeitia, E.4    Del Rio, J.5
  • 10
    • 49549103772 scopus 로고    scopus 로고
    • PACAP38 increases vesicular monoamine transporter 2 (VMAT2) expression and attenuates methamphetamine toxicity
    • 18533255 10.1016/j.npep.2008.04.003 1:CAS:528:DC%2BD1cXhtVeis7%2FL
    • Guillot TS, Richardson JR, Wang MZ et al (2008) PACAP38 increases vesicular monoamine transporter 2 (VMAT2) expression and attenuates methamphetamine toxicity. Neuropeptides 42:423-434
    • (2008) Neuropeptides , vol.42 , pp. 423-434
    • Guillot, T.S.1    Richardson, J.R.2    Wang, M.Z.3
  • 11
    • 0342546527 scopus 로고    scopus 로고
    • BDNF blocks caspase-3 activation in neonatal hypoxia-ischemia
    • 10671321 10.1006/nbdi.1999.0275 1:STN:280:DC%2BD3c7jvVGgsA%3D%3D
    • Han BH, D'Costa A, Back SA et al (2000) BDNF blocks caspase-3 activation in neonatal hypoxia-ischemia. Neurobiol Dis 7:38-53
    • (2000) Neurobiol Dis , vol.7 , pp. 38-53
    • Han, B.H.1    D'Costa, A.2    Back, S.A.3
  • 12
    • 5644228612 scopus 로고    scopus 로고
    • PINK, PANK, or PARK? A clinicians' guide to familial parkinsonism
    • 15488458 10.1016/S1474-4422(04)00905-6 1:CAS:528:DC%2BD2cXhtVaks7jM
    • Healy DG, Abou-Sleiman PM, Wood NW (2004) PINK, PANK, or PARK? A clinicians' guide to familial parkinsonism. Lancet Neurol 3:652-662
    • (2004) Lancet Neurol , vol.3 , pp. 652-662
    • Healy, D.G.1    Abou-Sleiman, P.M.2    Wood, N.W.3
  • 13
    • 41149163183 scopus 로고    scopus 로고
    • Parkinson's disease: Clinical features and diagnosis
    • 18344392 10.1136/jnnp.2007.131045 1:STN:280:DC%2BD1c7oslamtA%3D%3D
    • Jankovic J (2008) Parkinson's disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry 79:368-376
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , pp. 368-376
    • Jankovic, J.1
  • 14
    • 38349168650 scopus 로고    scopus 로고
    • The attenuating effect of memantine on staurosporine-, salsolinol- and doxorubicin-induced apoptosis in human neuroblastoma SH-SY5Y cells
    • 10.1016/j.neuint.2007.10.003 1:CAS:528:DC%2BD1cXhsVKgs7g%3D
    • Jantas D, Pytel M, Mozrzymas JW et al (2008) The attenuating effect of memantine on staurosporine-, salsolinol- and doxorubicin-induced apoptosis in human neuroblastoma SH-SY5Y cells. Eurochem Int 52:864-877
    • (2008) Eurochem Int , vol.52 , pp. 864-877
    • Jantas, D.1    Pytel, M.2    Mozrzymas, J.W.3
  • 15
    • 24644509224 scopus 로고    scopus 로고
    • BDNF protects neurons following injury by modulation of caspase activity
    • 16159102 10.1385/NCC:3:1:071 1:CAS:528:DC%2BD2MXhtFWqsLvE
    • Kim DH, Zhao X (2005) BDNF protects neurons following injury by modulation of caspase activity. Neurocrit Care 3:71-76
    • (2005) Neurocrit Care , vol.3 , pp. 71-76
    • Kim, D.H.1    Zhao, X.2
  • 16
    • 61949278122 scopus 로고    scopus 로고
    • When and how should treatment be started in Parkinson disease
    • 19221313 10.1212/WNL.0b013e318198e177 1:CAS:528:DC%2BD1MXhslygsL4%3D
    • Lang AE (2009) When and how should treatment be started in Parkinson disease. Neurology 72:S39-S43
    • (2009) Neurology , vol.72
    • Lang, A.E.1
  • 17
    • 84868213729 scopus 로고    scopus 로고
    • Multimodal neuroprotection induced by PACAP38 in oxygen-glucose deprivation and middle cerebral artery occlusion stroke models
    • 22678884 10.1007/s12031-012-9818-1 1:CAS:528:DC%2BC38XhtlKkurbI
    • Lazarovici P, Cohen G, Arien-Zakay H et al (2012) Multimodal neuroprotection induced by PACAP38 in oxygen-glucose deprivation and middle cerebral artery occlusion stroke models. J Mol Neurosci 48:526-540
    • (2012) J Mol Neurosci , vol.48 , pp. 526-540
    • Lazarovici, P.1    Cohen, G.2    Arien-Zakay, H.3
  • 18
    • 1642323631 scopus 로고    scopus 로고
    • Tyrosine hydroxylase transcription depends primarily on cAMP response element activity, regardless of the type of inducing stimulus
    • 15033181 10.1016/j.mcn.2003.10.010 1:CAS:528:DC%2BD2cXitFKmtrg%3D
    • Lewis-Tuffin LJ, Quinn PG, Chikaraishi DM (2004) Tyrosine hydroxylase transcription depends primarily on cAMP response element activity, regardless of the type of inducing stimulus. Mol Cell Neurosci 25:536-547
    • (2004) Mol Cell Neurosci , vol.25 , pp. 536-547
    • Lewis-Tuffin, L.J.1    Quinn, P.G.2    Chikaraishi, D.M.3
  • 19
    • 77749233728 scopus 로고    scopus 로고
    • The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice
    • 20154710 10.1038/aps.2010.3
    • Li N, Liu GT (2010) The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice. Acta Pharmacol Sin 31:265-272
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 265-272
    • Li, N.1    Liu, G.T.2
  • 20
    • 16544388655 scopus 로고    scopus 로고
    • Neuroprotective function of R-(-)-1-(benzofuran-2-yl)-2- propylaminopentane, [R-(-)-BPAP], against apoptosis induced by N-methyl(R)salsolinol, an endogenous dopaminergic neurotoxin, in human dopaminergic neuroblastoma SH-SY5Y cells
    • 15102525 10.1016/j.lfs.2003.12.001 1:CAS:528:DC%2BD2cXjsVWrtb0%3D
    • Maruyama W, Yi H, Takahashi T et al (2004) Neuroprotective function of R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane, [R-(-)-BPAP], against apoptosis induced by N-methyl(R)salsolinol, an endogenous dopaminergic neurotoxin, in human dopaminergic neuroblastoma SH-SY5Y cells. Life Sci 75:107-117
    • (2004) Life Sci , vol.75 , pp. 107-117
    • Maruyama, W.1    Yi, H.2    Takahashi, T.3
  • 21
    • 0026539332 scopus 로고
    • Binding sites for pituitary adenylate cyclase activating polypeptide (PACAP): Comparison with vasoactive intestinal polypeptide (VIP) binding site localization in rat brain sections
    • 1324082 10.1016/0006-8993(92)90430-H 1:CAS:528:DyaK38Xit1ylsL8%3D
    • Masuo Y, Ohtaki T, Masuda Y, Tsuda M, Fujino M (1992) Binding sites for pituitary adenylate cyclase activating polypeptide (PACAP): comparison with vasoactive intestinal polypeptide (VIP) binding site localization in rat brain sections. Brain Res 575:113-123
    • (1992) Brain Res , vol.575 , pp. 113-123
    • Masuo, Y.1    Ohtaki, T.2    Masuda, Y.3    Tsuda, M.4    Fujino, M.5
  • 22
    • 0027476845 scopus 로고
    • Regional distribution of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat central nervous system as determined by sandwich-enzyme immunoassay
    • 10.1016/0006-8993(93)90241-E
    • Masuo Y, Suzuki N, Matsumoto H et al (1993) Regional distribution of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat central nervous system as determined by sandwich-enzyme immunoassay. Brain Res 602:657-663
    • (1993) Brain Res , vol.602 , pp. 657-663
    • Masuo, Y.1    Suzuki, N.2    Matsumoto, H.3
  • 23
    • 17844365594 scopus 로고    scopus 로고
    • Genetics of Parkinson's disease
    • 16026116 10.1080/07853890510007269 1:CAS:528:DC%2BD2MXjvFWqsbk%3D
    • Morris HR (2005) Genetics of Parkinson's disease. Ann Med 37:86-96
    • (2005) Ann Med , vol.37 , pp. 86-96
    • Morris, H.R.1
  • 24
    • 84868203425 scopus 로고    scopus 로고
    • IL-6 and PACAP receptor expression and localization after global brain ischemia in mice
    • 22669509 10.1007/s12031-012-9819-0 1:CAS:528:DC%2BC38XhtlKkurbM
    • Nakamachi T, Tsuchida M, Kagami N et al (2012) IL-6 and PACAP receptor expression and localization after global brain ischemia in mice. J Mol Neurosci 48:518-525
    • (2012) J Mol Neurosci , vol.48 , pp. 518-525
    • Nakamachi, T.1    Tsuchida, M.2    Kagami, N.3
  • 25
    • 0346154811 scopus 로고    scopus 로고
    • Dopamine-derived salsolinol derivatives as endogenous monoamine oxidase inhibitors: Occurrence, metabolism and function in human brains
    • 14697894 10.1016/S0161-813X(03)00099-8 1:CAS:528:DC%2BD3sXhtVSjtLvN
    • Naoi M, Maruyama W, Nagy GM (2004) Dopamine-derived salsolinol derivatives as endogenous monoamine oxidase inhibitors: occurrence, metabolism and function in human brains. Neurotoxicology 25:193-204
    • (2004) Neurotoxicology , vol.25 , pp. 193-204
    • Naoi, M.1    Maruyama, W.2    Nagy, G.M.3
  • 26
    • 0033964778 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide (VIP) prevents neurotoxicity in neuronal cultures: Relevance to neuroprotection in Parkinson's disease
    • 10784133 10.1016/S0006-8993(99)02375-6 1:CAS:528:DC%2BD3cXhtlyitL0%3D
    • Offen D, Sherki Y, Melamed E, Fridkin M, Brenneman DE, Gozes I (2000) Vasoactive intestinal peptide (VIP) prevents neurotoxicity in neuronal cultures: relevance to neuroprotection in Parkinson's disease. Brain Res 854:257-262
    • (2000) Brain Res , vol.854 , pp. 257-262
    • Offen, D.1    Sherki, Y.2    Melamed, E.3    Fridkin, M.4    Brenneman, D.E.5    Gozes, I.6
  • 27
    • 84867807348 scopus 로고    scopus 로고
    • Limiting spinal cord injury by pharmacological intervention
    • 23098731 10.1016/B978-0-444-52137-8.00029-2
    • Priestley JV, Michael-Titus AT, Tetziaff W (2012) Limiting spinal cord injury by pharmacological intervention. Handb Clin Neurol 109:463-484
    • (2012) Handb Clin Neurol , vol.109 , pp. 463-484
    • Priestley, J.V.1    Michael-Titus, A.T.2    Tetziaff, W.3
  • 28
    • 77951206413 scopus 로고    scopus 로고
    • Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF
    • 20109548 10.1016/j.nbd.2010.01.013 1:CAS:528:DC%2BC3cXksFCmtL0%3D
    • Puerta E, Hervias I, Barros-Minones L et al (2010) Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF. Neurobiol Dis 38:237-245
    • (2010) Neurobiol Dis , vol.38 , pp. 237-245
    • Puerta, E.1    Hervias, I.2    Barros-Minones, L.3
  • 30
    • 33746467019 scopus 로고    scopus 로고
    • Involvement of ERK and CREB signaling pathways in the protective effect of PACAP in monosodium glutamate-induced retinal lesion
    • 16891269 10.1196/annals.1317.070 1:CAS:528:DC%2BD28XpvVehu7k%3D
    • Racz B, Tamas A, Kiss P et al (2006) Involvement of ERK and CREB signaling pathways in the protective effect of PACAP in monosodium glutamate-induced retinal lesion. Ann N Y Acad Sci 1070:507-511
    • (2006) Ann N y Acad Sci , vol.1070 , pp. 507-511
    • Racz, B.1    Tamas, A.2    Kiss, P.3
  • 31
    • 84855712568 scopus 로고    scopus 로고
    • Toxic effects of low alcohol and nicotine combinations in SH-SY5Y cells are apoptotically mediated
    • 21222065 10.1007/s12640-011-9239-x 1:CAS:528:DC%2BC3MXhtFGnsrrO
    • Ramlochansingh C, Taylor RE, Tizabi Y (2011) Toxic effects of low alcohol and nicotine combinations in SH-SY5Y cells are apoptotically mediated. Neurotox Res 20:263-269
    • (2011) Neurotox Res , vol.20 , pp. 263-269
    • Ramlochansingh, C.1    Taylor, R.E.2    Tizabi, Y.3
  • 32
    • 80052679017 scopus 로고    scopus 로고
    • Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice
    • 21593432 10.1096/fj.10-180133 1:CAS:528:DC%2BC3MXhtFOht7vF
    • Rat D, Schmitt U, Tippmann F et al (2011) Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice. FASEB J 25:3208-3218
    • (2011) FASEB J , vol.25 , pp. 3208-3218
    • Rat, D.1    Schmitt, U.2    Tippmann, F.3
  • 33
    • 0034035403 scopus 로고    scopus 로고
    • Delayed systemic administration of PACAP38 is neuroprotective in transient middle cerebral artery occlusion in the rat
    • 10835464 10.1161/01.STR.31.6.1411
    • Reglödi D, Somogyvari-Vigh A, Vigh S, Kozicz T, Arimura A (2000) Delayed systemic administration of PACAP38 is neuroprotective in transient middle cerebral artery occlusion in the rat. Stroke 31:1411-1417
    • (2000) Stroke , vol.31 , pp. 1411-1417
    • Reglödi, D.1    Somogyvari-Vigh, A.2    Vigh, S.3    Kozicz, T.4    Arimura, A.5
  • 34
    • 7044227726 scopus 로고    scopus 로고
    • Morphological and functional effects of PACAP in 6-hydroxydopamine- induced lesion of the substantia nigra in rats
    • 15518897 10.1016/j.regpep.2004.05.016
    • Reglödi D, Tamas A, Lubics A, Szalontay L, Lengvari I (2004) Morphological and functional effects of PACAP in 6-hydroxydopamine-induced lesion of the substantia nigra in rats. Regul Pept 123:85-94
    • (2004) Regul Pept , vol.123 , pp. 85-94
    • Reglödi, D.1    Tamas, A.2    Lubics, A.3    Szalontay, L.4    Lengvari, I.5
  • 35
    • 33746456340 scopus 로고    scopus 로고
    • Comparative study on the effects of PACAP in young, aging, and castrated males in a rat model of Parkinson's disease
    • 16888218 10.1196/annals.1317.072
    • Reglödi D, Tamas A, Lengvari I, Toth G, Szalontay L, Lubics A (2006) Comparative study on the effects of PACAP in young, aging, and castrated males in a rat model of Parkinson's disease. Ann NY Acad Sci 1070:518-524
    • (2006) Ann NY Acad Sci , vol.1070 , pp. 518-524
    • Reglödi, D.1    Tamas, A.2    Lengvari, I.3    Toth, G.4    Szalontay, L.5    Lubics, A.6
  • 36
    • 79958167912 scopus 로고    scopus 로고
    • Review on the protective effect of PACAP in models of neurodegenerative diseases in vitro and in vivo
    • 21524257 10.2174/138161211795589355
    • Reglödi D, Kiss P, Lubics A, Tamas A (2011) Review on the protective effect of PACAP in models of neurodegenerative diseases in vitro and in vivo. Curr Pharm Des 17:962-972
    • (2011) Curr Pharm des , vol.17 , pp. 962-972
    • Reglödi, D.1    Kiss, P.2    Lubics, A.3    Tamas, A.4
  • 37
    • 84868198185 scopus 로고    scopus 로고
    • PACAP is an endogenous protective factor-insights from PACAP-deficient mice
    • 22528455 10.1007/s12031-012-9762-0
    • Reglödi D, Kiss P, Szabadfi K et al (2012) PACAP is an endogenous protective factor-insights from PACAP-deficient mice. J Mol Neurosci 48:482-492
    • (2012) J Mol Neurosci , vol.48 , pp. 482-492
    • Reglödi, D.1    Kiss, P.2    Szabadfi, K.3
  • 38
    • 2542596183 scopus 로고    scopus 로고
    • Parkinson's disease
    • 15172778 10.1016/S0140-6736(04)16305-8 1:CAS:528:DC%2BD2cXksVanu7k%3D
    • Samii A, Nutt JG, Ransom BR (2004) Parkinson's disease. Lancet 363:1783-1793
    • (2004) Lancet , vol.363 , pp. 1783-1793
    • Samii, A.1    Nutt, J.G.2    Ransom, B.R.3
  • 39
    • 4444305508 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide: A potential neuroprotective peptide
    • 15379674 10.2174/1381612043383548 1:CAS:528:DC%2BD2cXmslKkuro%3D
    • Somogyvari-Vigh A, Reglödi D (2004) Pituitary adenylate cyclase activating polypeptide: a potential neuroprotective peptide. Curr Pharm Des 10:2861-2889
    • (2004) Curr Pharm des , vol.10 , pp. 2861-2889
    • Somogyvari-Vigh, A.1    Reglödi, D.2
  • 40
    • 84869399110 scopus 로고    scopus 로고
    • Understanding the substrate specificity of conventional calpains
    • 22944687 10.1515/hsz-2012-0143 1:CAS:528:DC%2BC38XhsVGiur3J
    • Sorimachi H, Mamitsuka H, Ono Y (2012) Understanding the substrate specificity of conventional calpains. Biol Chem 393:853-871
    • (2012) Biol Chem , vol.393 , pp. 853-871
    • Sorimachi, H.1    Mamitsuka, H.2    Ono, Y.3
  • 41
    • 18344395117 scopus 로고    scopus 로고
    • Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: Studies using heterologous expression systems of the dopamine transporter
    • 11911843 10.1016/S0006-2952(01)00922-4 1:CAS:528:DC%2BD38XitFWlsrk%3D
    • Storch A, Ott S, Hwang YI et al (2002) Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: studies using heterologous expression systems of the dopamine transporter. Biochem Pharmacol 63:909-920
    • (2002) Biochem Pharmacol , vol.63 , pp. 909-920
    • Storch, A.1    Ott, S.2    Hwang, Y.I.3
  • 42
    • 5044234125 scopus 로고    scopus 로고
    • Neuropeptide PACAP inhibits hypoxic activation of brain microglia: A protective mechanism against microglial neurotoxicity in ischemia
    • 15476707 10.1016/j.brainres.2004.08.017 1:CAS:528:DC%2BD2cXot12ju7g%3D
    • Suk K, Park JH, Lee WH (2004) Neuropeptide PACAP inhibits hypoxic activation of brain microglia: a protective mechanism against microglial neurotoxicity in ischemia. Brain Res 1026:151-156
    • (2004) Brain Res , vol.1026 , pp. 151-156
    • Suk, K.1    Park, J.H.2    Lee, W.H.3
  • 43
    • 84856243830 scopus 로고    scopus 로고
    • Mice deficient in pituitary adenylate cyclase activating polypeptide (PACAP) are more susceptible to retinal ischemic injury in vivo
    • 21717232 10.1007/s12640-011-9254-y 1:CAS:528:DC%2BC3MXhs1GhtLzJ
    • Szabadfi K, Atlasz T, Kiss P et al (2012) Mice deficient in pituitary adenylate cyclase activating polypeptide (PACAP) are more susceptible to retinal ischemic injury in vivo. Neurotox Res 21:41-48
    • (2012) Neurotox Res , vol.21 , pp. 41-48
    • Szabadfi, K.1    Atlasz, T.2    Kiss, P.3
  • 44
    • 84864352714 scopus 로고    scopus 로고
    • Effect of PACAP in central and peripheral nerve injuries
    • 22942712 10.3390/ijms13078430 1:CAS:528:DC%2BC38XhtVCiu73O
    • Tamas A, Reglödi D, Farkas O et al (2012a) Effect of PACAP in central and peripheral nerve injuries. Int J Mol Sci 13:8430-8448
    • (2012) Int J Mol Sci , vol.13 , pp. 8430-8448
    • Tamas, A.1    Reglödi, D.2    Farkas, O.3
  • 45
    • 84861457185 scopus 로고    scopus 로고
    • Comparative examination of inner ear in wild type and pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice
    • 22203609 10.1007/s12640-011-9298-z 1:CAS:528:DC%2BC38Xjs1Clt7o%3D
    • Tamas A, Szabadfi K, Nemeth A et al (2012b) Comparative examination of inner ear in wild type and pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice. Neurotox Res 21:435-444
    • (2012) Neurotox Res , vol.21 , pp. 435-444
    • Tamas, A.1    Szabadfi, K.2    Nemeth, A.3
  • 46
    • 84868215248 scopus 로고    scopus 로고
    • Neuroprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on spinal cord injury
    • 22674051 10.1007/s12031-012-9817-2 1:CAS:528:DC%2BC38XhtlKkurbN
    • Tsuchikawa D, Nakamachi T, Tsuchida M et al (2012) Neuroprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on spinal cord injury. J Mol Neurosci 48:508-517
    • (2012) J Mol Neurosci , vol.48 , pp. 508-517
    • Tsuchikawa, D.1    Nakamachi, T.2    Tsuchida, M.3
  • 47
    • 84858866417 scopus 로고    scopus 로고
    • Antioxidant and anti-apoptotic activity of vasoactive intestinal peptide (VIP) against 6-hydroxy dopamine toxicity in the rat corpus striatum
    • 21850490 10.1007/s12031-011-9618-z 1:CAS:528:DC%2BC38XosFKhtg%3D%3D
    • Tuncel N, Korkmaz OT, Tekin N, Sener E, Akyuz F, Inal M (2012) Antioxidant and anti-apoptotic activity of vasoactive intestinal peptide (VIP) against 6-hydroxy dopamine toxicity in the rat corpus striatum. J Mol Neurosci 46:51-57
    • (2012) J Mol Neurosci , vol.46 , pp. 51-57
    • Tuncel, N.1    Korkmaz, O.T.2    Tekin, N.3    Sener, E.4    Akyuz, F.5    Inal, M.6
  • 48
    • 0034700111 scopus 로고    scopus 로고
    • The neuroprotective effect of pituitary adenylate cyclase-activating polypeptide on cerebellar granule cells in mediated through inhibition of the CED3-related cysteine protease caspase-3/CPP32
    • 11087878 10.1073/pnas.97.24.13390 1:CAS:528:DC%2BD3cXosVOjsL4%3D
    • Vaudry D, Gonzalez BJ, Basille M et al (2000) The neuroprotective effect of pituitary adenylate cyclase-activating polypeptide on cerebellar granule cells in mediated through inhibition of the CED3-related cysteine protease caspase-3/CPP32. Proc Natl Acad Sci USA 97:13390-13395
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13390-13395
    • Vaudry, D.1    Gonzalez, B.J.2    Basille, M.3
  • 49
    • 70349922918 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery
    • 19805477 10.1124/pr.109.001370 1:CAS:528:DC%2BC3cXhsVWmu7vK
    • Vaudry D, Falluel-Morel A, Bougault S et al (2009) Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev 61:283-357
    • (2009) Pharmacol Rev , vol.61 , pp. 283-357
    • Vaudry, D.1    Falluel-Morel, A.2    Bougault, S.3
  • 50
    • 3242695252 scopus 로고    scopus 로고
    • Genes, proteins, and neurotoxins involved in Parkinson's disease
    • 10.1016/j.pneurobio.2004.05.002
    • von Bohlen, Halbach O, Schober A, Krieglstein K (2004) Genes, proteins, and neurotoxins involved in Parkinson's disease. Prog Neurobiol 73:151-177
    • (2004) Prog Neurobiol , vol.73 , pp. 151-177
    • Von Bohlen1    Halbach, O.2    Schober, A.3    Krieglstein, K.4
  • 51
    • 21844450845 scopus 로고    scopus 로고
    • PACAP protects neuronal differentiated PC12 cells against the neurotoxicity induced by a mitochondrial complex i inhibitor, rotenone
    • 16004991 10.1016/j.febslet.2005.06.013 1:CAS:528:DC%2BD2MXmt1eisrw%3D
    • Wang G, Qi C, Fan GH, Zhou HY, Chen SD (2005) PACAP protects neuronal differentiated PC12 cells against the neurotoxicity induced by a mitochondrial complex I inhibitor, rotenone. FEBS Lett 579:4005-4011
    • (2005) FEBS Lett , vol.579 , pp. 4005-4011
    • Wang, G.1    Qi, C.2    Fan, G.H.3    Zhou, H.Y.4    Chen, S.D.5
  • 52
    • 44649200377 scopus 로고    scopus 로고
    • Neuroprotective effects of PACAP27 in mice model of Parkinson's disease involved in the modulation of K (ATP) subunits and D2 receptors in the striatum
    • 18440632 10.1016/j.npep.2008.03.002 1:CAS:528:DC%2BD1cXmvFSrsLw%3D
    • Wang G, Pan J, Tan YY et al (2008) Neuroprotective effects of PACAP27 in mice model of Parkinson's disease involved in the modulation of K (ATP) subunits and D2 receptors in the striatum. Neuropeptides 42:267-276
    • (2008) Neuropeptides , vol.42 , pp. 267-276
    • Wang, G.1    Pan, J.2    Tan, Y.Y.3
  • 53
    • 0037646486 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP(1-38)) enhances N-methyl-d-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1
    • 12524444 10.1074/jbc.M209141200 1:CAS:528:DC%2BD3sXhvV2itLs%3D
    • Yaka R, He DY, Phamluong K, Ron D (2003) Pituitary adenylate cyclase-activating polypeptide (PACAP(1-38)) enhances N-methyl-d-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1. J Biol Chem 278:9630-9963
    • (2003) J Biol Chem , vol.278 , pp. 9630-9963
    • Yaka, R.1    He, D.Y.2    Phamluong, K.3    Ron, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.