메뉴 건너뛰기




Volumn 19, Issue 3, 2011, Pages 423-434

Neuroprotective effects of PACAP against ethanol-induced toxicity in the developing rat cerebellum

Author keywords

Cell death; Cerebellum; Differentiation; Ethanol; PACAP

Indexed keywords

ALCOHOL; CASPASE 3; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; PROTEIN C JUN;

EID: 79951957765     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12640-010-9186-y     Document Type: Article
Times cited : (27)

References (42)
  • 1
    • 0035881044 scopus 로고    scopus 로고
    • Acute exposure of cerebellar granule neurons to ethanol suppresses stress-activated protein kinase-1 and concomitantly induces AP-1
    • DOI 10.1006/taap.2001.9229
    • GK Acquaah-Mensah SW Leslie JP Kehrer 2001 Acute exposure of cerebellar granule neurons to ethanol suppresses stress-activated protein kinase-1 and concomitantly induces AP-1 Toxicol Appl Pharmacol 175 10 18 1:CAS:528: DC%2BD3MXlvFKgu7w%3D 10.1006/taap.2001.9229 11509022 (Pubitemid 32783531)
    • (2001) Toxicology and Applied Pharmacology , vol.175 , Issue.1 , pp. 10-18
    • Acquaah-Mensah, G.K.1    Leslie, S.W.2    Kehrer, J.P.3
  • 2
    • 0027169379 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide (PACAP) can cross the vascular component of the blood-testis barrier in the mouse
    • WA Banks AJ Kastin G Komaki A Arimura 1993 Pituitary adenylate cyclase activating polypeptide (PACAP) can cross the vascular component of the blood-testis barrier in the mouse J Androl 14 170 173 1:CAS:528: DyaK2cXhtVaqsLY%3D 8407571 (Pubitemid 23219244)
    • (1993) Journal of Andrology , vol.14 , Issue.3 , pp. 170-173
    • Banks, W.A.1    Kastin, A.J.2    Komaki, G.3    Arimura, A.4
  • 3
    • 33750972552 scopus 로고    scopus 로고
    • Ontogeny of PACAP receptors in the human cerebellum: Perspectives of therapeutic applications
    • DOI 10.1016/j.regpep.2006. 03.010, PII S0167011506001157
    • M Basille A Falluel-Morel D Vaudry N Aubert A Fournier P Freger N Gallo-Payet H Vaudry B Gonzalez 2006 Ontogeny of PACAP receptors in the human cerebellum: perspectives of therapeutic applications Regul Pept 137 27 33 1:CAS:528:DC%2BD28Xht1ersr3E 10.1016/j.regpep.2006.03.010 16963135 (Pubitemid 44751194)
    • (2006) Regulatory Peptides , vol.137 , Issue.1-2 , pp. 27-33
    • Basille, M.1    Falluel-Morel, A.2    Vaudry, D.3    Aubert, N.4    Fournier, A.5    Freger, P.6    Gallo-Payet, N.7    Vaudry, H.8    Gonzalez, B.9
  • 4
    • 57449113473 scopus 로고    scopus 로고
    • Alcohol impairs long-term depression at the cerebellar parallel fiber-Purkinje cell synapse
    • 1:CAS:528:DC%2BD1MXnsV2kuw%3D%3D 10.1152/jn.90384.2008 18922952
    • A Belmeguenai P Botta JT Weber M Carta M De Ruiter CI De Zeeuw CF Valenzuela C Hansel 2008 Alcohol impairs long-term depression at the cerebellar parallel fiber-Purkinje cell synapse J Neurophysiol 100 3167 3174 1:CAS:528:DC%2BD1MXnsV2kuw%3D%3D 10.1152/jn.90384.2008 18922952
    • (2008) J Neurophysiol , vol.100 , pp. 3167-3174
    • Belmeguenai, A.1    Botta, P.2    Weber, J.T.3    Carta, M.4    De Ruiter, M.5    De Zeeuw, C.I.6    Valenzuela, C.F.7    Hansel, C.8
  • 5
    • 0347717735 scopus 로고    scopus 로고
    • Phosphatidylinositol 3′-OH kinase and protein kinase A pathways mediate the anti-apoptotic effect of pituitary adenylyl cyclase-activating polypeptide in cultured cerebellar granule neurons: Modulation by ethanol
    • SV Bhave PL Hoffman 2004 Phosphatidylinositol 3'-OH kinase and protein kinase A pathways mediate the anti-apoptotic effect of pituitary adenylyl cyclase-activating polypeptide in cultured cerebellar granule neurons: modulation by ethanol J Neurochem 88 359 369 1:CAS:528:DC%2BD2cXntlSqtw%3D%3D 10.1046/j.1471-4159.2003.02167.x 14690524 (Pubitemid 38084552)
    • (2004) Journal of Neurochemistry , vol.88 , Issue.2 , pp. 359-369
    • Bhave, S.V.1    Hoffman, P.L.2
  • 6
    • 43049125784 scopus 로고    scopus 로고
    • Novel stable PACAP analogs with potent activity towards the PAC1 receptor
    • 1:CAS:528:DC%2BD1cXlvVClsLk%3D 10.1016/j.peptides.2008.01.022 18353507
    • S Bourgault D Vaudry B Botia A Couvineau M Laburthe H Vaudry A Fournier 2008 Novel stable PACAP analogs with potent activity towards the PAC1 receptor Peptides 29 919 932 1:CAS:528:DC%2BD1cXlvVClsLk%3D 10.1016/j.peptides.2008.01. 022 18353507
    • (2008) Peptides , vol.29 , pp. 919-932
    • Bourgault, S.1    Vaudry, D.2    Botia, B.3    Couvineau, A.4    Laburthe, M.5    Vaudry, H.6    Fournier, A.7
  • 7
    • 0032942438 scopus 로고    scopus 로고
    • Peptide transport and metabolism across the placenta
    • DOI 10.1016/S0169-409X (99)00006-X, PII S0169409X9900006X
    • GA Chandorkar C Ampasavate JF Stobaugh KL Audus 1999 Peptide transport and metabolism across the placenta Adv Drug Deliv Rev 38 59 67 1:CAS:528:DyaK1MXjs1ehtLk%3D 10.1016/S0169-409X(99)00006-X 10837746 (Pubitemid 29216953)
    • (1999) Advanced Drug Delivery Reviews , vol.38 , Issue.1 , pp. 59-67
    • Chandorkar, G.A.1    Ampasavate, C.2    Stobaugh, J.F.3    Audus, K.L.4
  • 8
    • 35548965042 scopus 로고    scopus 로고
    • Lead-induced alterations of apoptosis and neurotrophic factor mRNA in the developing rat cortex, hippocampus, and cerebellum
    • DOI 10.1002/jbt.20191
    • SL Chao JM Moss GJ Harry 2007 Lead-induced alterations of apoptosis and neurotrophic factor mRNA in the developing rat cortex, hippocampus, and cerebellum J Biochem Mol Toxicol 21 265 272 1:CAS:528:DC%2BD2sXht1KmsLbO 10.1002/jbt.20191 17912701 (Pubitemid 350006283)
    • (2007) Journal of Biochemical and Molecular Toxicology , vol.21 , Issue.5 , pp. 265-272
    • Chao, S.L.1    Moss, J.M.2    Harry, G.J.3
  • 9
    • 0032790449 scopus 로고    scopus 로고
    • Prenatal alcohol use among teenagers: Effects on neonatal outcomes
    • DOI 10.1111/j.1530-0277.1999.tb04284.x
    • MD Cornelius L Goldshmidt PM Taylor NL Day 1999 Prenatal alcohol use among teenagers: effects on neonatal outcomes Alcohol Clin Exp Res 23 1238 1244 1:STN:280:DyaK1MzntFGqsA%3D%3D 10.1111/j.1530-0277.1999.tb04284.x 10443992 (Pubitemid 29352813)
    • (1999) Alcoholism: Clinical and Experimental Research , vol.23 , Issue.7 , pp. 1238-1244
    • Cornelius, M.D.1    Goldshmidt, L.2    Taylor, P.M.3    Day, N.L.4
  • 11
    • 40949113125 scopus 로고    scopus 로고
    • D-JNKi, a peptide inhibitor of c-Jun N-terminal kinase, promotes functional recovery after transient focal cerebral ischemia in rats
    • 1:CAS:528:DC%2BD1cXjs1KqtLc%3D 10.1016/j.neuroscience.2007.12.036 18262367
    • E Esneault V Castagne P Moser C Bonny M Bernaudin 2008 D-JNKi, a peptide inhibitor of c-Jun N-terminal kinase, promotes functional recovery after transient focal cerebral ischemia in rats Neuroscience 152 308 320 1:CAS:528:DC%2BD1cXjs1KqtLc%3D 10.1016/j.neuroscience.2007.12.036 18262367
    • (2008) Neuroscience , vol.152 , pp. 308-320
    • Esneault, E.1    Castagne, V.2    Moser, P.3    Bonny, C.4    Bernaudin, M.5
  • 12
    • 9744245931 scopus 로고    scopus 로고
    • Opposite regulation of the mitochondrial apoptotic pathway by C2-ceramide and PACAP through a MAP-kinase-dependent mechanism in cerebellar granule cells
    • DOI 10.1111/j.1471-4159.2004.02810.x
    • A Falluel-Morel N Aubert D Vaudry M Basille M Fontaine A Fournier H Vaudry BJ Gonzalez 2004 Opposite regulation of the mitochondrial apoptotic pathway by C2-ceramide and PACAP through a MAP-kinase-dependent mechanism in cerebellar granule cells J Neurochem 91 1231 1243 1:CAS:528:DC%2BD2cXhtFSitr%2FN 10.1111/j.1471-4159.2004.02810.x 15569266 (Pubitemid 39587461)
    • (2004) Journal of Neurochemistry , vol.91 , Issue.5 , pp. 1231-1243
    • Falluel-Morel, A.1    Aubert, N.2    Vaudry, D.3    Basille, M.4    Fontaine, M.5    Fournier, A.6    Vaudry, H.7    Gonzalez, B.J.8
  • 14
    • 4644337361 scopus 로고    scopus 로고
    • 2, Bad and Bax mRNA occurs in the rat cerebellum within hours after ethanol exposure on postnatal day 4 but not on postnatal day 9
    • DOI 10.1016/j.molbrainres.2004. 06.034, PII S0169328X04003134
    • Y Ge SM Belcher DR Pierce KE Light 2004 Altered expression of Bcl2, Bad and Bax mRNA occurs in the rat cerebellum within hours after ethanol exposure on postnatal day 4 but not on postnatal day 9 Mol Brain Res 129 124 134 1:CAS:528:DC%2BD2cXotlCksL0%3D 10.1016/j.molbrainres.2004.06.034 15469889 (Pubitemid 39304256)
    • (2004) Molecular Brain Research , vol.129 , Issue.1-2 , pp. 124-134
    • Ge, Y.1    Belcher, S.M.2    Pierce, D.R.3    Light, K.E.4
  • 15
    • 0031562366 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide promotes cell survival and neurite outgrowth in rat cerebellar neuroblasts
    • DOI 10.1016/S0306-4522(96) 00617-3, PII S0306452296006173
    • BJ Gonzalez M Basille D Vaudry A Fournier H Vaudry 1997 Pituitary adenylate cyclase-activating polypeptide promotes cell survival and neurite outgrowth in rat cerebellar neuroblasts Neuroscience 78 419 430 1:CAS:528:DyaK2sXjtFCntrk%3D 10.1016/S0306-4522(96)00617-3 9145799 (Pubitemid 27170334)
    • (1997) Neuroscience , vol.78 , Issue.2 , pp. 419-430
    • Gonzalez, B.J.1    Basille, M.2    Vaudry, D.3    Fournier, A.4    Vaudry, H.5
  • 16
    • 0036619408 scopus 로고    scopus 로고
    • Mechanisms involved in central nervous system dysfunctions induced by prenatal ethanol exposure
    • 1:CAS:528:DC%2BD38Xntl2ksLo%3D 10.1080/1029842021000010884 12829422
    • C Guerri 2002 Mechanisms involved in central nervous system dysfunctions induced by prenatal ethanol exposure Neurotox Res 4 327 335 1:CAS:528: DC%2BD38Xntl2ksLo%3D 10.1080/1029842021000010884 12829422
    • (2002) Neurotox Res , vol.4 , pp. 327-335
    • Guerri, C.1
  • 17
    • 33645231716 scopus 로고    scopus 로고
    • Ethanol induces cell death by activating caspase-3 in the rat cerebral cortex
    • 1:CAS:528:DC%2BD2MXht1KqsL7P 16267392
    • JY Han Y Joo YS Kim YK Lee HJ Kim GJ Cho WS Choi SS Kang 2005 Ethanol induces cell death by activating caspase-3 in the rat cerebral cortex Mol Cells 20 189 195 1:CAS:528:DC%2BD2MXht1KqsL7P 16267392
    • (2005) Mol Cells , vol.20 , pp. 189-195
    • Han, J.Y.1    Joo, Y.2    Kim, Y.S.3    Lee, Y.K.4    Kim, H.J.5    Cho, G.J.6    Choi, W.S.7    Kang, S.S.8
  • 19
    • 0034635370 scopus 로고    scopus 로고
    • Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome
    • DOI 10.1126/science.287.5455.1056
    • C Ikonomidou P Bittigau MJ Ishimaru DF Wozniak C Koch K Genz MT Price V Stefovska F Horster T Tenkova K Dikranian JW Olney 2000 Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome Science 287 1056 1060 1:CAS:528:DC%2BD3cXhtFyqur4%3D 10.1126/science.287.5455.1056 10669420 (Pubitemid 30094364)
    • (2000) Science , vol.287 , Issue.5455 , pp. 1056-1060
    • Ikonomidou, C.1    Bittigau, P.2    Koch, C.3    Genz, K.4    Stefovska, V.5    Horster, F.6
  • 20
    • 0015918403 scopus 로고
    • Pattern of malformation in offspring of chronic alcoholic mothers
    • 1:STN:280:DyaE3s3lvFSltA%3D%3D 10.1016/S0140-6736(73)91291-9 4126070
    • KL Jones DW Smith CN Ulleland P Streissguth 1973 Pattern of malformation in offspring of chronic alcoholic mothers Lancet 1 1267 1271 1:STN:280:DyaE3s3lvFSltA%3D%3D 10.1016/S0140-6736(73)91291-9 4126070
    • (1973) Lancet , vol.1 , pp. 1267-1271
    • Jones, K.L.1    Smith, D.W.2    Ulleland, C.N.3    Streissguth, P.4
  • 21
    • 0032519658 scopus 로고    scopus 로고
    • Distinct modes of neuronal migration in different domains of developing cerebellar cortex
    • H Komuro P Rakic 1998 Distinct modes of neuronal migration in different domains of developing cerebellar cortex J Neurosci 18 1478 1490 1:CAS:528:DyaK1cXptlyjtA%3D%3D 9454856 (Pubitemid 28082432)
    • (1998) Journal of Neuroscience , vol.18 , Issue.4 , pp. 1478-1490
    • Komuro, H.1    Rakic, P.2
  • 22
    • 0031014623 scopus 로고    scopus 로고
    • Differential alteration of hippocampal synaptic strength induced by pituitary adenylate cyclase activating polypeptide-38 (PACAP-38)
    • DOI 10.1016/S0304-3940(96) 13323-1, PII S0304394096133231
    • T Kondo T Tominaga M Ichikawa T Iijima 1997 Differential alteration of hippocampal synaptic strength induced by pituitary adenylate cyclase activating polypeptide-38 (PACAP-38) Neurosci Lett 221 189 192 1:CAS:528: DyaK2sXns1egsA%3D%3D 10.1016/S0304-3940(96)13323-1 9121696 (Pubitemid 27049230)
    • (1997) Neuroscience Letters , vol.221 , Issue.2-3 , pp. 189-192
    • Kondo, T.1    Tominaga, T.2    Ichikawa, M.3    Iijima, T.4
  • 23
    • 0028846049 scopus 로고
    • Effects of intracerebroventricular administration of pituitary adenylate cyclase-activating polypeptide (PACAP) on the motor activity and reserpine-induced hypothermia in murines
    • 1:CAS:528:DyaK2MXpvVyktb8%3D 10.1016/0006-8993(95)00978-Y 8624713
    • Y Masuo J Noguchi S Morita Y Matsumoto 1995 Effects of intracerebroventricular administration of pituitary adenylate cyclase-activating polypeptide (PACAP) on the motor activity and reserpine-induced hypothermia in murines Brain Res 700 219 226 1:CAS:528:DyaK2MXpvVyktb8%3D 10.1016/0006-8993(95) 00978-Y 8624713
    • (1995) Brain Res , vol.700 , pp. 219-226
    • Masuo, Y.1    Noguchi, J.2    Morita, S.3    Matsumoto, Y.4
  • 25
    • 0033165994 scopus 로고    scopus 로고
    • NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus
    • T Miyata T Maeda JE Lee 1999 NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus Genes Dev 13 1647 1652 1:CAS:528:DyaK1MXkvVCku78%3D 10.1101/gad.13.13.1647 10398678 (Pubitemid 29325870)
    • (1999) Genes and Development , vol.13 , Issue.13 , pp. 1647-1652
    • Miyata, T.1    Maeda, T.2    Lee, J.E.3
  • 26
    • 34548380454 scopus 로고    scopus 로고
    • Cerebellar information processing and visuospatial functions
    • DOI 10.1080/14734220701230870, PII 772825097
    • M Molinari MG Leggio 2007 Cerebellar information processing and visuospatial functions Cerebellum 6 214 220 10.1080/14734220701230870 17786817 (Pubitemid 47360069)
    • (2007) Cerebellum , vol.6 , Issue.3 , pp. 214-220
    • Molinari, M.1    Leggio, M.G.2
  • 27
    • 0032479939 scopus 로고    scopus 로고
    • Expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the postnatal and adult rat cerebellar cortex
    • HS Nielsen J Hannibal J Fahrenkrug 1998 Expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the postnatal and adult rat cerebellar cortex Neuroreport 9 2639 2642 1:CAS:528:DyaK1cXlvVCltL8%3D 10.1097/00001756-199808030-00039 9721947 (Pubitemid 28387163)
    • (1998) NeuroReport , vol.9 , Issue.11 , pp. 2639-2642
    • Nielsen, H.S.1    Hannibal, J.2    Fahrenkrug, J.3
  • 28
    • 0031681412 scopus 로고    scopus 로고
    • The cerebellum in the spatial problem solving: A co-star or a guest star?
    • DOI 10.1016/S0301-0082(98) 00036-7, PII S0301008298000367
    • L Petrosini MG Leggio M Molinari 1998 The cerebellum in the spatial problem solving: a co-star or a guest star? Prog Neurobiol 56 191 210 1:STN:280:DyaK1cvjtlCisg%3D%3D 10.1016/S0301-0082(98)00036-7 9760701 (Pubitemid 28432565)
    • (1998) Progress in Neurobiology , vol.56 , Issue.2 , pp. 191-210
    • Petrosini, L.1    Leggio, M.G.2    Molinari, M.3
  • 30
    • 0242330832 scopus 로고    scopus 로고
    • Ethanol-Induced Oxidative Stress Precedes Mitochondrially Mediated Apoptotic Death of Cultured Fetal Cortical Neurons
    • DOI 10.1002/jnr.10767
    • V Ramachandran LT Watts SK Maffi J Chen S Schenker G Henderson 2003 Ethanol-induced oxidative stress precedes mitochondrially mediated apoptotic death of cultured fetal cortical neurons J Neurosci Res 74 577 588 1:CAS:528:DC%2BD3sXovVyht7c%3D 10.1002/jnr.10767 14598302 (Pubitemid 37352080)
    • (2003) Journal of Neuroscience Research , vol.74 , Issue.4 , pp. 577-588
    • Ramachandran, V.1    Watts, L.T.2    Maffi, S.K.3    Chen, J.4    Schenker, S.5    Henderson, G.I.6
  • 31
    • 0028817392 scopus 로고
    • Alcohol selectively attenuates stress-induced c-fos expression in rat hippocampus
    • 1:CAS:528:DyaK2MXjtFeqsLg%3D 7823175
    • AE Ryabinin KR Melia M Cole FE Bloom MC Wilson 1995 Alcohol selectively attenuates stress-induced c-fos expression in rat hippocampus J Neurosci 15 721 730 1:CAS:528:DyaK2MXjtFeqsLg%3D 7823175
    • (1995) J Neurosci , vol.15 , pp. 721-730
    • Ryabinin, A.E.1    Melia, K.R.2    Cole, M.3    Bloom, F.E.4    Wilson, M.C.5
  • 32
    • 0032519872 scopus 로고    scopus 로고
    • Neuronal basic helix-loop-helix proteins (NEX, neuroD, NDRF): Spatiotemporal expression and targeted disruption of the NEX gene in transgenic mice
    • MH Schwab S Druffel-Augustin M Jung M Klugmann A Bartholomae MJ Rossner KA Nave 1998 Neuronal basic helix-loop-helix proteins (NEX, neuroD, NDRF): spatiotemporal expression and targeted disruption of the NEX gene in transgenic mice J Neurosci 18 1408 1418 1:CAS:528:DyaK1cXptlyjsg%3D%3D 9454850 (Pubitemid 28082426)
    • (1998) Journal of Neuroscience , vol.18 , Issue.4 , pp. 1408-1418
    • Schwab, M.H.1    Druffel-Augustin, S.2    Gass, P.3    Jung, M.4    Klugmann, M.5    Bartholomae, A.6    Rossner, M.J.7    Nave, K.-A.8
  • 33
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH 0034
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH 0034
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 34
    • 0028181651 scopus 로고
    • 6 subunit mRNA in granule cells of the cerebellar cortex and cochlear nuclei: Expression in developing and mutant mice
    • DOI 10.1002/cne.903390304
    • L Varecka CH Wu A Rotter A Frostholm 1994 GABAA/benzodiazepine receptor alpha 6 subunit mRNA in granule cells of the cerebellar cortex and cochlear nuclei: expression in developing and mutant mice J Comp Neurol 339 341 352 1:CAS:528:DyaK2cXhsFCntrw%3D 10.1002/cne.903390304 8132866 (Pubitemid 24012947)
    • (1994) Journal of Comparative Neurology , vol.339 , Issue.3 , pp. 341-352
    • Varecka, L.1    Wu, C.-H.2    Rotter, A.3    Frostholm, A.4
  • 36
    • 0034700111 scopus 로고    scopus 로고
    • The neuroprotective effect of pituitary adenylate cyclase-activating polypeptide on cerebellar granule cells is mediated through inhibition of the CED3-related cysteine protease caspase-3/CPP32
    • 1:CAS:528:DC%2BD3cXosVOjsL4%3D 10.1073/pnas.97.24.13390 11087878
    • D Vaudry BJ Gonzalez M Basille TF Pamantung M Fontaine A Fournier H Vaudry 2000 The neuroprotective effect of pituitary adenylate cyclase-activating polypeptide on cerebellar granule cells is mediated through inhibition of the CED3-related cysteine protease caspase-3/CPP32 Proc Natl Acad Sci USA 97 13390 13395 1:CAS:528:DC%2BD3cXosVOjsL4%3D 10.1073/pnas.97.24.13390 11087878
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13390-13395
    • Vaudry, D.1    Gonzalez, B.J.2    Basille, M.3    Pamantung, T.F.4    Fontaine, M.5    Fournier, A.6    Vaudry, H.7
  • 39
    • 0031027331 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway
    • M Villalba J Bockaert L Journot 1997 Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway J Neurosci 17 83 90 1:CAS:528:DyaK2sXmsFWk 8987738 (Pubitemid 27008852)
    • (1997) Journal of Neuroscience , vol.17 , Issue.1 , pp. 83-90
    • Villalba, M.1    Bockaert, J.2    Journot, L.3
  • 41
    • 0027209577 scopus 로고
    • Developmental expression of the α6 GABA(A) receptor subunit mRNA occurs only after cerebellar granule cell migration
    • DOI 10.1016/0165-3806(93)90068-L
    • T Zheng MR Santi P Bovolin LN Marlier DR Grayson 1993 Developmental expression of the alpha 6 GABAA receptor subunit mRNA occurs only after cerebellar granule cell migration Dev Brain Res 75 91 103 1:CAS:528: DyaK3sXms1eju74%3D 10.1016/0165-3806(93)90068-L (Pubitemid 23265091)
    • (1993) Developmental Brain Research , vol.75 , Issue.1 , pp. 91-103
    • Zheng, T.1    Santi, M.-R.2    Bovolin, P.3    Marlier, L.N.J.-L.4    Grayson, D.R.5
  • 42
    • 0037928769 scopus 로고    scopus 로고
    • The role of dipeptidyl peptidase IV in the cleavage of glucagon family peptides: In vivo metabolism of pituitary adenylate cyclase-activating polypeptide-(1-38)
    • DOI 10.1074/jbc.M212355200
    • L Zhu C Tamvakopoulos D Xie J Dragovic X Shen JE Fenyk-Melody K Schmidt A Bagchi PR Griffin NA Thornberry R Sinha Roy 2003 The role of dipeptidyl peptidase IV in the cleavage of glucagon family peptides: in vivo metabolism of pituitary adenylate cyclase activating polypeptide-(1-38) J Biol Chem 278 22418 22423 1:CAS:528:DC%2BD3sXksF2isL0%3D 10.1074/jbc.M212355200 12690116 (Pubitemid 36830293)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.25 , pp. 22418-22423
    • Zhu, L.1    Tamvakopoulos, C.2    Xie, D.3    Dragovic, J.4    Shen, X.5    Fenyk-Melody, J.E.6    Schmidt, K.7    Bagchi, A.8    Griffin, P.R.9    Thornberry, N.A.10    Roy, R.S.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.