The effect of experimentally induced chronic hyperglycaemia on serum and pancreatic insulin, pancreatic islet IGF-I and plasma and urinary ketones in the domestic cat (Felis felis)

General and Comparative Endocrinology

Volumn 188, Issue 1, 2013, Pages 269-281

  Link, Karl R J ^a,b   Allio, Ileana ^a   Rand, Jacqueline S ^b   Eppler, Elisabeth ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Diabetes; Feline; Glucagon; Glucose toxicity; IGF I; Insulin

Indexed keywords

3 HYDROXYBUTYRIC ACID; CHOLESTEROL; GLUCAGON; GLUCOSE; GLYCEROL; INSULIN; KETONE; LIPID; NEUTRAL INSULIN; SOMATOMEDIN C; TRIACYLGLYCEROL;

ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CAT; CONTROLLED STUDY; GLUCOSE INFUSION; HYPERGLYCEMIA; HYPERLIPIDEMIA; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN SYNTHESIS; KETONURIA; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TREATMENT OUTCOME;

EID: 84878898245     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1016/j.ygcen.2013.04.029     Document Type: Article

References (60)

1. Auer V.J., Janas E., Ninichuk V., Eppler E., Weiss T.S., Kirchner S., Otto A.M., Stangl M.J. Extracellular factors and immunosuppressive drugs influencing insulin secretion of murine islets. Clin. Exp. Immunol. 2012, 170:238-247.
2. Berishvili G., Shved N., Eppler E., Clota F., Baroiller J.F., Reinecke M. Organ-specific expression of IGF-I during early development of bony fish as revealed in the tilapia, Oreochromis niloticus, by in situ hybridization and immunohistochemistry: indication for the particular importance of local IGF-I. Cell Tissue Res. 2006, 325:287-301.
3. Berwert L., Segner H., Reinecke M. Ontogeny of IGF-1 and the classical islet hormones in the turbot Scophthalmus maximus. Peptides 1995, 16:113-122.
4. Boysen S.R. Fluid and electrolyte therapy in endocrine disorders: diabtes mellitus and hypoadrenocorticism. Vet. Clin. North Am. Small Anim. Pract. 2008, 38:699-717.
5. Clarenburg R. Carbohydrate metabolism, lipid metabolism. Physiological Chemistry of Domestic Animals 1992, 239-333. Mosby Year Book, Sydney. R.W. Reinhardt, M. Steube (Eds.).
6. Clemmons D.R. Metabolic actions of insulin-like growth factor-I in normal physiology and diabetes. Endocrinol. Metab. Clin. North Am. 2012, 41:425-443.
7. Cole T.G., Klotzsch S.G., McNamara J.R. Measurement of triglyceride concentration. Laboratory Measurement of Lipids, Lipoproteins and Apolipoporoteins 1994, 81-90. AACC Press, Washington DC. N. Rifai, G.R. Warwick (Eds.).
8. Dinarello C.A., Donath M.Y., Mandrup-Poulsen T. Role of IL-1β in type 2 diabetes. Curr. Opin. Endocrinol. 2010, 17:314-321.
9. Dohan F.C., Lukens F.D. Experimental diabetes produced by the administration of glucose. Endocrinology 1948, 42:244-262.
10. Donath M.Y., Böni-Schnetzler M. Cytokine production by islets in health and diabetes: cellular origin, regulation and function. Trends Endocrinol. Metab. 2010, 21:261-267.
11. Donath M.Y., Ehses J.A., Maedler K., Schumann D.M., Ellingsgaard H., Eppler E., Reinecke M. Mechanism of beta-cell death in type 2 diabetes. Diabetes 2005, 54:108-113.
12. Ehses J.A., Perren A., Eppler E., Ribaux P., Pospisilik J.A., Maor-Cahn R., Gueripel X., Ellingsgaard H., Schneider M.K., Biollaz G., Fontana A., Reinecke M., Homo-Delarche F., Donath M.Y. Increased number of islet-associated macrophages in type 2 diabetes. Diabetes 2007, 56:2356-2370.
13. Ehses J.A., Ellingsgaard H., Böni-Schnetzler M., Donath M.Y. Pancreatic islet inflammation in type 2 diabetes: from α and β cell compensationto dysfunction. Arch. Physiol. Biochem. 2009, 115:240-247.
14. Ellingsgaard H., Hauselmann I., Schuler B., Habib A.M., Baggio L.L., Meier D.T., Eppler E., Bouzakri K., Wueest S., Muller Y.D., Hansen A.M., Reinecke M., Konrad D., Gassmann M., Reimann F., Halban P.A., Gromada J., Drucker D.J., Gribble F.M., Ehses J.A., Donath M.Y. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat. Med. 2011, 17:1481-1489.
15. Feldman E.C., Nelson R.W. Diabetes mellitus. Canine and Feline Endocrinology and Reproduction 2004, 558-615. Saunders, Maryland Heights. third ed. E.C. Feldman, R.W. Nelson (Eds.).
16. Filippich L.J. Renal clearance studies in cats with chronic renal disease: dietary implications. J. Small Anim. Pract. 1992, 33:191-196.
17. Furuzawa Y., Ohmori Y., Watanabe T. Immunohistochemical morphometry of pancreatic islets in the cat. J. Vet. Med. Sci. 1992, 54:1165-1173.
18. Hall D.G., Kelley L.C., Gray M.L., Glaus T.M. Lymphocytic inflammation of pancreatic islets in a diabetic cat. J. Vet. Diagn. Invest. 1997, 9:98-100.
19. Hill D.J., Petrik J., Arany E., McDonald T.J., Delovitch T.L. Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice. J. Endocrinol. 1999, 161:153-165.
20. Hu X.L., Zhu M.Y., Zhang Z.H., Hou R., Shen F.J., Li F.Z., Zhang A.J. Cloning, characterization and tissue specific expression of amur tiger (Panthera tigris altaica) IGF-1. Biosci. Biotech. Biochem. 2006, 70:1846-1854.
21. Imamura T., Koffler M., Helderman J.H., Prince D., Thirlby R., Inman L., Unger R.H. Severe diabetes induced in subtotally depancreatized dogs by sustained hyperglycemia. Diabetes 1988, 37:600-609.
22. Jevdjovic T., Maake C., Eppler E., Zoidis E., Reinecke M., Zapf J. Effects of insulin-like growth factor-I treatment on the endocrine pancreas of hypophysectomized rats: comparison with growth hormone replacement. Eur. J. Endocrinol. 2004, 151:223-231.
23. Jevdjovic T., Maake C., Zwimpfer C., Krey G., Eppler E., Zapf J., Reinecke M. The effect of hypophysectomy on pancreatic islet hormone and insulin-like growth factor I content and mRNA expression in rat. Histochem. Cell Biol. 2005, 123:179-188.
24. Larsen C.M., Faulenbach M., Vaag A., Vølund A., Ehses J.A., Seifert B., Mandrup-Poulsen T., Donath M.Y. Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N. Engl. J. Med. 2007, 356:1517-1526.
25. Link, K.R., 2001. Feline diabetes mellitus: Diagnostics and experimental modelling. PhD Thesis, The University of Queensland, Australia, THE16117=library Call Number, p. 340.
26. Link K.R., Rand J.S. Reference values for glucose tolerance and glucose tolerance status in cats. J. Am. Vet. Med. Assoc. 1998, 213:492-496.
27. Link K.R., Rand J.S. Changes in blood glucose concentration are associated with relatively rapid changes in circulating fructosamine concentrations in cats. J. Feline Med. Surg. 2008, 10:583-592.
28. Link K.R., Rand J.S., Hendrikz J.K. Evaluation of a simplified intravenous glucose tolerance test and a reflectance glucose meter for use in cats. Vet. Rec. 1997, 140:253-256.
29. Loffing-Cueni D., Schmid A.C., Graf H., Reinecke M. IGF-I in the bony fish Cottus scorpius: cDNA, expression and differential localization in brain and islets. Mol. Cell Endocrinol. 1998, 141:187-194.
30. Lutz T.A., Rand J.S. Comparison of five commercial radioimmunoassay kits for the measurement of feline insulin. Res. Vet. Sci. 1993, 55:64-69.
31. Lutz T.A., Rand J.S. Pathogenesis of feline diabetes mellitus. Vet. Clin. North Am. Small Anim. Pract. 1995, 25:527-552.
32. Maake C., Reinecke M. Immunohistochemical localization of insulin-like growth factor 1 and 2 in the endocrine pancreas of rat, dog, and man, and their coexistence with classical islet hormones. Cell Tissue Res. 1993, 273:249-259.
33. Maake C., Hanke W., Reinecke M. An immunohistochemical and morphometric analysis of insulin, insulin-like growth factor I, glucagon, somatostatin, and PP in the development of the gastro-entero-pancreatic system of Xenopus laevis. Gen. Comp. Endocrinol. 1998, 110:182-195.
34. Maedler K., Schumann D.M., Sauter N., Ellingsgaard H., Bosco D., Baertschiger R., Iwakura Y., Oberholzer J., Wollheim C.B., Gauthier B.R., Donath M.Y. Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets. Diabetes 2006, 55:2713-2722.
35. Marshall R.D., Rand J.S., Morton J.M. Treatment of newly diagnosed cats with glarginine insulin improves glycemic control and results in higher probability od remission than protamine zinc and lente insulins. J. Feline Med. Surg. 2009, 11:683-691.
36. Nosadini R., Avogaro A., Doria A., Fioretto P., Trevisan R., Morocutti A. Ketone body metabolism: a physiological and clinical overview. Diabetes Metab. Rev. 1989, 5:299-319.
37. O'Brien T.D., Hayden D.W., Johnson K.J., Fletcher T.F. Immunhistochemical morphometry of pancreatic endocrine cells in diabetic, normoglycaemic glucose-intolerant and normal cats. J. Comp. Pathol. 1986, 96:357-369.
38. Olson W.G., Link K.R.J., Otterby D.E., Stevens J.B. Assessment of sodium deficiency and polyuria/polydipsia in dairy cows. Bov. Pract. 1989, 24:126-133.
39. Onda M. Fluorescence histochemical study of the pancreas in the cat. Gastroenterol. Jpn. 1976, 11:246-261.
40. Palin K., Bluthé R.M., McCusker R.H., Moos F., Dantzer R., Kelley K.W. TNFalpha induced sickness behavior in mice with functional 55 kD TNF receptors is blocked by central IGF-I. J. Neuroimmunol. 2007, 187:55-60.
41. Park S.-E., Dantzer R., Kelley K.W., McCusker R.H. Central administration of insulin-like growth factor I decreases depressive-like behavior and brain cytokine expression in mice. J. Neuroinflammat. 2011, 8:12.
42. Petkov P.E. Histochimie du pancreas du chat avec discussion du tissue Langerhansien endocrine. Histochemie 1967, 11:305-318.
43. Rand J.S. Pathogenesis of feline diabetes. Vet. Clin. North Am. Small Anim. Pract. 2013, 10.1016/j.ccsm.2013.01.03.
44. Reinecke M., Collet C. The phylogeny of the insulin-like growth factors. Int. Rev. Cytol. 1998, 183:1-94.
45. Reinecke M., Maake C., Falkmer S., Sara V.R. The branching of insulin-like growth factor 1 and insulin: an immunohistochemical analysis during phylogeny. Regul. Pept. 1993, 48:65-76.
46. Reinecke M., Broger I., Brun R., Zapf J., Maake C. Immunohistochemical localization of insulin-like growth factor I and II in the endocrine pancreas of birds, reptiles, and amphibia. Gen. Comp. Endocrinol. 1995, 100:385-396.
47. Reinecke M., Schmid A., Ermatinger R., Loffing-Cueni D. Insulin-like growth factor I in the teleost Oreochromis mossambicus, the tilapia: gene sequence, tissue expression, and cellular localization. Endocrinology 1997, 138:3613-3619.
48. Reusch C.E., Kley S., Casella M., Nelson R.W., Mol J., Zapf J. Measurements of growth hormone and insulin-like growth factor 1 in cats with diabetes mellitus. Vet. Rec. 2006, 158:195-200.
49. Roomp K., Rand J.S. Intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine. J. Feline Med. Surg. 2009, 11:668-682.
50. Shapiro A.M., Lakey J.R., Ryan E.A., Korbutt G.S., Toth E., Warnock G.L., Kneteman N.M., Rajotte R.V. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N. Engl. J. Med. 2000, 343:230-238.
51. Shved N., Berishvili G., Mazel P., Baroiller J.-F., Eppler E. Growth hormone (GH) treatment acts on the endocrine and autocrine/paracrine GH/IGF-axis and on TNF-a expression in bony fish pituitary and immune organ. Fish Shellfish Immunol. 2011, 31:944-952.
52. Spinas G.A., Palmer J.B., Mandrup-Poulsen T., Andersen H., Nielsen J.H., Nerup J. The bimodal effect of interleukin-1 on rat pancreatic beta-cells - stimulation followed by inhibition - depends upon dose, duration of exposure, and ambient glucose concentration. Acta Endocrinol. (Copenh.) 1988, 119:307-311.
53. Tai M.M. A mathematical model for the determination of total area under glucose tolerance and other metabolic curves. Diabetes Care 1994, 17:152-154.
54. Toreson W.E. Glycogen infiltration (so-called hydropic degeneration) in the pancreas in human and experimental diabetes mellitus. Am. J. Pathol. 1951, 27:327-347.
55. Tschuor F., Zini E., Schellenberg S., Wenger M., Boretti F.S., Reusch C.E. Evaluation of four methods used to measure plasma insulin-like growth factor 1 concentrations in healthy cats and cats with diabetes mellitus or other diseases. Am. J. Vet. Res. 2012, 73:1925-1931.
56. Uronen-Hansson H., Allen M.L., Lichtarowicz-Krynska E., Aynsley-Green A., Cole T.J., Höiden-Guthenberg I., et al. Growth hormone enhances proinflammatory cytokine production by monocytes in whole blood. Growth Horm. IGF Res. 2003, 13:282-286.
57. Whitney M.S. Diagnostic approach to hyperlipidemia. Consultations in Feline Internal Medicine 1994, 177-182. W.B. Saunders, Sydney. J.R. August (Ed.).
58. Wieczorek G., Pospichil A., Perentes E. A comparative immunohistochemical study of pancreatic islets in laboratory animals (rats, dogs, minipigs, nonhuman primates). Exp. Toxicol. Pathol. 1998, 50:151-172.
59. Zapf J., Waldvogel M. Protein kinase and cyclic AMP-binding activities in liver and adipose tissue of normal, streptozotocin-diabetic and adrenalectomized rats. FEBS Lett. 1973, 36:253-256.
60. Zini E., Osto M., Franchini M., Guscetti F., Donath M.Y., Perren A., Heller R.S., Linscheid P., Bouwman M., Ackermann M., Lutz T.A., Reusch C.E. Hyperglycaemia but not hyperlipidaemia causes beta cell dysfunction and beta cell loss in the domestic cat. Diabetologia 2009, 52:336-346.