The phylogeny of the insulin-like growth factors

International Review of Cytology

Volumn 183, Issue , 1998, Pages 1-94

  Reinecke, Manfred ^a   Collet, Chris ^b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Binding proteins; Evolution; Genes; Insulin like growth factors; Invertebrates; Ligands; Receptors; Vertebrates

Indexed keywords

GROWTH FACTOR; LIGAND; SOMATOMEDIN;

CHORDATA; DEVELOPMENT; EVOLUTION; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; VERTEBRATE;

CHORDATA; INVERTEBRATA; MAMMALIA; VERTEBRATA;

EID: 0031949025     PISSN: 00747696     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0074-7696(08)60142-4     Document Type: Review

References (411)

1. Acerini, C. L., Clayton, K. L., Hintz, R., Baker, B., Watts, A., Holly, J. M. P., and Dunger, D. B. (1996). Serum insulin-like growth factor II levels in normal adolescents and those with insulin-dependent diabetes mellitus. Clin. Endocrinol. 45, 13-19.
2. Adachi, T., Takiya, S., Suzuki, Y., Iwami, M., Kawakami, A., Takahashi, S. Y., Ishizaki, H., Nagasawa, H., and Suzuki, A. (1989). cDNa structure and expression of bombyxin, an insulin-like brain secretory peptide of the silkmoth Bombyx mori. J. Biol. Chem. 264, 7681-7685.
3. Adams, S. O., Nissley, S. P., Handwerger, S., and Rechler, M. M. (1983). Developmental patterns of insulin-like growth factor I and II sythesis and regulation in rat fibroblasts. Nature 302, 150-153.
4. Adashi E. Y. (1994). Growth factors and ovarian function: The IGF-I paradigm. Horm. Res. 42, 44-48.
5. Adern, A. S., Jossan, S. S., D'Argy, R., Gillberg, P. G., Nordberg, A., Winblad, B., and Sara, V. R. (1989). Insulin-like growth factor 1 (IGF-1) receptors in the human brain: Quantitative autoradiographic localisation. Brain Res. 503, 299-303.
6. Alexandrides T. K., and Smith, R. J. (1989). A novel fetal insulin-like growth factor (IGF) I receptor. Mechanism for increased IGF I- and insulin-stimulated tyrosine kinase activity in fetal muscle. J. Biol. Chem. 264, 12922-12930.
7. Allander, S. V. (1995). "Organisation and Regulation of Insulin-like Growth Factor Binding Protein Genes." Ph.D. thesis. Karolinska Hospital, Stockholm.
8. Allander, S. V., Larsson, C., Ehrenborg, E., Suwanichkul, A., Weber, G., Morris, S. L., Bajalica, S., Kiefer, M. C., Luthman, H., and Powell, D. R. (1994). Characterisation of the chromosomal gene and promoter for human insulin-like growth factor binding protein-5. J. Biol. Chem. 269, 10891-10898.
9. Andersen, A. S., Kjeldsen, T., Wiberg, F. C., Christensen, P. M., Rasmussen, J. S., Norris, K., Moller, K. B., and Moller, N. P. H. (1990). Changing the insulin receptor to possess insulin-like growth factor I ligand specificity. Biochemistry 29, 7363-7366.
10. Anderson, T. A., and Matthews, S. J. (1995). Insulin like growth factors and their binding proteins in fish. Abstracts Proc. Endocrinol. Soc. Aust. 38, 64.
11. Anderson, T. A., Bennett, L. R., Conlon, M. A., and Owens, P. C. (1993). Immunoreactive and receptor-active insulin-like growth factor I (IGF-I) and IGF-binding protein in blood plasma from the freshwater fish Macquaria ambigua (golden perch). J. Endocrinol. 136, 191-198.
12. Andersson, I., Billig, H., Fryklund, L., Hansson, H.-A., Isaksson, O., Isgaard, J., Nilsson, A-, Rozell, B., Skottner, A., and Stemme, S. (1986). Localisation of IGF-I in adult rats. Immunohistochemical studies. Acta Physiol. Scand. 126, 311-312.
13. Andersson, I., Edwall, D., Norstedt, G., Rozell, B., Skottner, A., and Hansson, H.-A. (1988). Different expression of insulin-like growth factor I in the developing and adult rat brain. Acta Physiol. Scand. 132, 167-173.
14. Armstrong, D. G., and Hogg, C. O. (1996). Insulin-like growth factor I (IGF-I), IGF-II and type I IGF receptor gene expression in the ovary of the egg laying hen. J. Reprod. Fertil. 106, 101-106.
15. Armstrong, D. G., McKay, C. O., Morell, D. J., and Goddard, C. (1989). Insulin-like growth factor-I binding proteins in serum from domestic fowl. J. Endocrinol. 120, 373-378.
16. Asfari, M., DeNoel, W. M., Holthuizen, P. E., and Czernichow, P. (1995). Insulin-like growth factor-II gene expression in rat insulin-producing beta-cell line (INS-1) is regulated by glucose. Diabetologia 38, 927-935.
17. Bajalica, S., Vilhelmsdotter, S., Ehrenborg, E., Brodum-Nielsen, K., Luthman, H., and Larsson, C. (1992). Localisation of the human insulin-like growth factor-binding protein 4 gene to chromosomal region 17q12-21.1. Hum. Genet. 89, 234-236.
18. Ballard, F. J., Johnson, R. J., Owens, P. C., Francis, G. L., Upton, F. M., McMurtry, J. P., and Wallace, J. C. (1990). Chicken insulin-like growth factor-I: Amino acid sequence, radioimmunoassay, and plasma levels between strains and during growth. Gen. Comp. Endocrinol. 79, 459-468.
19. Barlow, D. P. (1995). Gametic imprinting in mammals. Science 270, 1610-1613.
20. Bautista, C. M., Mohan, S., and Baylink, D. J. (1990). Insulin-like growth factors I and II are present in the skeletal tissues of ten vertebrates. Metabolism 39, 96-100.
21. r 140,000 growth-hormone dependent insulin-like growth factor binding protein complex, determination by reconstitution and affinity-labelling. Proc. Natl. Acad. Sci. USA 86, 6898-6902.
22. Bayne, M. L., Cascieri, M. A., Kelder, B., Applebaum, J., Chicci, G., Shapiro, J. A., Pasleau, F., and Kopchick, J. J. (1987). The C of human insulin-like growth factor (IGF) I is required for high affinity binding to type 1 IGF receptor. J. Biol. Chem. 264, 11004-11008.
23. Beck, F., Samani, N. J., Penschow, J. D., Thorley, B., Tregear, G. W., and Coghlan, J. P. (1987). Histochemical localization of IGF-I and -II mRNA in the developing rat embryo. Development 101,175-184.
24. Beck, F., Samani, N. J., Byrne, S., Morgan, K., Gebhard, R., and Brammar, W. J. (1988). Histochemical localization of IGF-I and IGF-II mRNA in the rat between birth and adulthood. Development 104, 29-39.
25. Bell, G. I., Merryweather, J. P., Sanchez-Pescador, R., Stempien, M. M., Priestley, L., Scott, J., and Rail, L. B. (1984). Sequence of a cDNA clone encoding human preproinsulin-like growth factor II. Nature 310, 775-777.
26. Bell, G. I., Gerhard, D. S., Fong, N. M., Sanchez-Pescador, R., and Rail, L. B. (1985). Isolation of the human insulin-like growth factor genes, insulin-like growth factor II and insulin genes are contiguous. Proc. Natl. Acad. Sci. USA 82, 6450-6454.
27. Bell, G. I., Stempien, M. M., Fong, N. M., and Rail, L. B. (1986). Sequences of liver cDNAs encoding two different mouse insulin-like growth factor I precursors. Nucleic Acids Res. 14, 7873-7882.
28. Bermudez, I., Beadle, D. J., Trifilieff, E., Luu, B., and Hietter, H. (1991). Electrophysiological activity of the C-peptide of the Locusta insulin-related peptide. FEBS Lett. 293, 137-141.
29. Bern, H. A., McCormick, S. D., Kelley, K. M., Gray, E. S., Nishioka, R. S., Madsen, S. S., and Tsai, P. L. (1991). Insulin-like growth factors "under water": Role in growth and function of fish and other poikilothermic vertebrates. In "Modern Concepts of Insulin-like Growth Factors" (E. M. Spencer, ed.), pp. 85-96. Elsevier, New York.
30. Berson, S. A., and Yalow, R. S. (1959). Quantitative aspects of the reaction between insulin and insulin-binding antibody. J. Clin. Invest. 38, 1996-2016.
31. Berwert, L., Segner, H., and Reinecke, M. (1995). Ontogeny of IGF-I and the classical islet hormones in the turbot, Scophthalmus maximus. Peptides 16, 113-122.
32. Besnard, N., Pisselet, C, Zapf, J., Hornebeck, W., Monniaux, D., and Monget, P. (1996). Proteolytic activity is involved in changes in intrafollicular insulin-like growth factor-binding protein levels during growth and atresia of ovine ovarian follicles. Endocrinology 137,1599-1607.
33. Binkert, C., Landwehr, J., Mary, J. L., Schwander, J., and Heinrich, G. (1989). Cloning, sequence analysis and expression of a cDNA encoding a novel insulin-like growth factor binding protein (IGFBP-2). EMBO J. 7, 2417-2423.
34. Blaise, O., Weil, C., and Le Bail, P.-Y. (1995). Role of IGF-I in the control of GH secretion in rainbow trout (Oncorhynchus mykiss). Growth Regal. 5, 142-150.
35. Blundell, T. L., and Humbel, R. E. (1980). Hormone families: Pancreatic hormones and homologous growth factors. Nature 287, 781-787.
36. Bondy, C. A., and Lee, W.-H. (1993). Patterns of insulin-like growth factor and IGF receptor gene expression in the brain. Ann. NY Acad. Sci. 692, 33-43.
37. Bondy, C. A., Werner, H., Roberts, C., and LeRoith, D. (1990). Cellular pattern of insulin-like growth factor-I and type-I IGF receptor gene expression in early organogenesis; comparison with IGF-II gene expression. Mol. Endocrinol. 4, 1386-1398.
38. Bondy, C. A., Werner, H., Roberts, C., and LeRoith, D. (1992). Cellular patterns of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: Comparison with insulin-like growth factors I and II. Neuroscience 46, 909-923.
39. Bondy, C. A., Chin, E., and Zhou, J. (1994). Significant species differences in local IGF-I and IGF-II expression. In "Current Directions in Insulin-like Growth Factor Research" (D. LeRoith and M. K. Raizada, eds.), pp. 73-77. Plenum, New York.
40. Bork, P. (1993). The modular architecture of a new family of growth regulators related to connective tissue growth factor. FEBS Lett. 327, 125-130.
41. Botero, L. F., Roberts, C. T., Jr., LeRoith, D., Adashi, E. Y., and Hernandez, E. R. (1993). Insulin-like growth factor I gene expression by primary cultures of ovarian cells: Insulin and dexamethasone dependence. Endocrinology 132, 2703-2708.
42. Brewer, M. T., Stetler, G. L., Squires, C. H., Thompson, R. C., Busby, W. H., and Clemmons, D. R. (1987). Cloning, characterization and expression of a human insulin-like growth factor binding protein. Biochem. Biophys. Res. Commun. 152, 1289-1297.
43. Brissenden, J. E., Ullrich, A., and Francke, U. (1984). Human chromosomal mapping of genes for insulin-like growth factors I and II and epidermal growth factor. Nature 310, 781-784.
44. Bryson, J. M., Tuch, B. E., and Baxter, R. C. (1989). Production of insulin-like growth factor-II by human fetal pancreas in culture. J. Endocrinol. 121, 367-373.
45. Burch, W. M., Weir, S., and Van Wyk, J. J. (1986). Embryonic chick cartilage produces its own somatomedin-like peptide to stimulate cartilage growth in vitro. Endocrinology 119, 1370-1376.
46. Buyalos, R. P. (1995). Insulin-like growth factors: Clinical experience in ovarian function. Am. J. Med. 98 (Suppl. 1A), 55S-66S.
47. Calvaruso, G., Vento, R., Giuliano, M., Lauricella, M., Gerbino, E., and Tesoriere, G. (1996). Insulin-like growth factors in chick embryo retina during development. Regul. Pept. 61, 19-25.
48. Cannizzaro, L. A., Croce, C. M., Griffin, C. A., Simeone, A., Boncicelli, E., and Huebner, K. (1987). Human homeo-box containing genes located at chromosome regions 2q31-q37 and 12q12-q13. Am. J. Hum. Genet. 41, 1-15.
49. Cao, Q. P., Duguay, S. J., Plisetskaya, E., Steiner, D. F., and Chan, S. J. (1989). Nucleotide sequence and growth hormone-regulated expression of salmon insulin-like growth factor 1 mRNA. Mol. Endocrinol. 3, 2005-2010.
50. Carlsson-Skwirut, C., Jörnvall, H., Holmgren, A., Andersson, C., Bergman, T., Lundquist, G., Sjögren, B., and Sara, V. R. (1986). Isolation and characterization of variant IGF-1 and IGF-2 from adult human brain. FEBS Lett. 201, 46-50.
51. Chan, S. J., Cao, Q.-P., and Steiner, D. F. (1990). Evolution of the insulin superfamily: Cloning of a hybrid insulin/insulin-like growth factor cDNA from amphioxus. Proc. Natl. Acad. Sci. USA 87, 9319-9323.
52. Chatelain, P., Naville, D., Avallet, O., Penhoat, A., Jaillard, C., Sanchez, P., and Saez, J. (1991). Paracrine and autocrine regulation of insulin-like growth factor I. Acta Pœdiatr. Scand. (Suppl.) 372, 92-95.
53. Chatelain, P. G., Avallet, M. O., Nicolino, M., Lejeune, H., Clark, A., Chuzel, F., Penhoat, and Saez, J. (1994). Insulin-like growth factor I actions on steroidogenesis. Acta Pœdiatr. Scand. 399, 176-177.
54. Chen, R. H., Sarnecki, C., and Blenis, J. (1992). Nuclear localization and regulation of erkand rsk-encoded protein kinases. Mol. Cell. Biol. 12, 915-927.
55. Cheng, H. L., Sullivan, K. A., and Feldman, E. L. (1996). Immunohistochemical localization of insulin-like growth factor binding protein-5 in the developing rat nervous system. Dev. Brain Res. 92, 211-218.
56. Chew, S. L., Lavender, Çlark, A. J. L., and Ross, R. J. M. (1995). An alternatively spliced human insulin-like growth factor I transcript with hepatic tissue expression that diverts away from mitogenic IBE1 peptide. Endocrinology 136, 1939-1944.
57. Chu, Y.-C., Hu, S.-Q., Zong, L., Burke, G. T., Gammeltoft, S., Chan, S. J., Steiner, D. F., and Katsoyannis, P. G. (1994). Insulin-like compounds related to amphioxus insulin-like peptide. Biochemistry 33, 11278-11285.
58. Clairmont, K. B., and Czech, M. P. (1989). Chicken and Xenopus mannose 6-phosphate receptors fail to bind insulin-like growth factor II. J. Biol. Chem. 264, 16390-16392.
59. Clemmons, D. R. (1992). IGF binding proteins: Regulation of cellular actions. Growth Regul. 2, 80-87.
60. Clemmons, D. R. (1993). IGF binding proteins and their functions. Mol. Reprod. Dev. 35, 368-375.
61. Clemmons, D. R., and Underwood, L. E. (1991). Nutritional regulation of IGF-I and IGF binding proteins. Annu. Rev. Nutr. 11, 393-412.
62. Collet, C., Candy, J., Richardson, N., and Sara, V. (1997). Organisation, sequence and expression of the gene encoding IGFII from barramundi (Teleosteii; Lates calcarifer). Biochem. Genetics 35, 211-224.
63. Collet, C., Candy, J., and Sara, V. (1998). Tyrosine hydroxylase and insulin-like growth factor II but not insulin are adjacent in the teleost species barramundi (Lates calcarifer). Submitted for publication.
64. Comings, D. E. (1972). The structure and function of chromatin. Adv. Hum. Genet. 3,237-431.
65. Conlon, J. M., Reinecke, M., Thorndyke, M. C., and Falkmer, S. (1988). Insulin and other islet hormones (somatostatin, glucagon and PP) in the neuroendocrine system of some lower vertebrates and that of invertebrates. Horm. Metab. Res. 20, 405-410.
66. Conti, F. G., Elliot, S. J., Striker, L. J., and Striker, G. E. (1989). Binding of insulin-like growth factor-I by glomerular endothelial and epithelial cells: Further evidence for IGF-1 action in the renal glomerulus. Biochem. Biophys. Res. Commun. 163, 952-958.
67. Crain, D. A., Gross, T. S., Cox, M. A., and Guilette, L. J. (1995a). Insulin-like growth factor-I in the plasma of two reptiles: Assay development and validations. Gen. Comp. Endocrinol. 98, 26-34.
68. Crain, D. A., Bolten, A. B., Bjorndal, K. A., Guilette, L. J., and Gross, T. S. (1995b). Size-dependent, sex-dependent, and seasonal changes in insulin-like growth factor I in the loggerhead sea turtle (Caretta caretta). Gen. Comp. Endocrinol. 98, 219-226.
69. Cutfield, J. F., Cutfield, S. M., Carne, A., Emdin, S. O., and Falkmer, S. (1986). The isolation, purification and amino-acid sequence of insulin from the teleost fish Cottus scorpius (daddy sculpin). Eur. J. Biochem. 158, 117-123.
70. Czech, M. P. (1985). The nature and regulation of the insulin receptor: Structure and function. Annu. Rev. Physiol. 47, 357-381.
71. Czech, M. P. (1989). Signal transmission by the insulin-like growth factors. Cell 59, 235-238.
72. Darling, D. C., and Brickell, P. M. (1996). Nucleotide sequence and genomic structure of the chicken insulin-like growth factor-II (IGF-II) coding region. Gen. Comp. Endocrinol. 102, 283-287.
73. Daughaday, W. H., and Rotwein, P. (1989). Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr. Rev. 10, 68-91.
74. Daughaday, W. H., Hall, K., Raben, M. S., Salmon, W. D., Jr., Van den Brande, J. L., and Van Wyk, J. J. (1972). Somatomedin: Proposed designation for sulphation factor. Nature 235, 107.
75. Daughaday, W. H., Kapadia, M., Yanow, C. E., Fabrick, K., and Mariz, I. K. (1985). Insulin-like growth factor 1 and II of nonmammalian sera. Gen. Comp. Endocrinol. 59, 316-325.
76. Daughaday, W. H., Hall, K., Salmon, W. D., Jr., Van den Brande, J. L., and Van Wyk, J. J. (1987). On the nomenclature of the somatomedins and insulin-like growth factors. J. Clin. Endocrinol. Metab. 65, 1075-1076.
77. De, W., Czernichow, P., and Asfari, M. (1996). Discordant regulation of insulin-like growth factor-II and insulin-like growth factor binding protein-2 gene expression in a rat b-cell line. Growth Regul. 6, 83-87.
78. De Loof, A., and Schoofs, L. (1990). Homologies between amino acid sequences of some vertebrate peptide hormones and peptides isolated from invertebrate sources. Comp. Biochem. Physiol. B 95, 459-468.
79. De Pablo, F., and de la Rosa, E. J. (1995). The developing CNS: A scenario for the action of proinsulin, insulin and insulin-like growth factors. Trends Neurosci. 18, 143-150.
80. De Pablo, F., Scott, L. A., and Roth, J. (1990). Insulin and insulin-like growth factor I in early development: Peptides, receptors and biological events. Endocr. Rev. 11, 558-577.
81. De Pablo, F., Robcis, H. L., Caldés, T., Alemany, J., Scavo, L., and Serrano, J. (1991). Insulin-like growth factor-I and insulin as growth and differentiation factors in chicken embryogenesis. Poultry Sci. 70, 1790-1796.
82. De Pablo, F., Pérez-Villamil, B., Serna, J., Gonzalez-Guerrero, P. R., Lopez-Carranza, A., de la Rosa, E., Alemany, J., and Caldéz, T. (1993). IGF-I and IGF-I receptor in development of nonmammalian vertebrates. Mol. Reprod. Dev. 35, 427-433.
83. De Pagter-Holthuizen, P., Jansen, M. M., van Schaik, F. M., van der Kammen, R., Oosterwijk, C., Van den Brande, J. L., and Sussenbach, J. S. (1987). The human insulin-like growth factor II gene contains two development-specific promoters. FEBS Lett. 214, 259-264.
84. D'Ercole, A. J., Stilles, A. D., and Underwood, L. E. (1984). Tissue concentrations of somatomedin C: Further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc. Natl. Acad. Sci. USA 81, 935-939.
85. D'Ercole, A. J., Ye, P., Calikoglu, A. S., and Gutierezospina, G. (1996). The role of the insulin-like growth factors in the central nervous system. Mol. Neurobiol. 13, 227-255.
86. Drakenberg, K., Sara, V. R., Lindahl, K. I., and Kewish, B. (1989). The study of insulin-like growth factors in Tilapia, Oreochromus mossambicus. Gen. Comp. Endocrinol. 74,173-180.
87. Drakenberg, K., Sara, V. R., Falkmer, S., Gammeltoft, S., Maake, C., and Reinecke, M. (1993). Identification of IGF-1 receptors in primitive vertebrates. Regul. Pept. 43, 73-82.
88. Drop, S. L. S., Schuller, A. G. P., Lindenbergh-Kortleve, D. J., Groffen, C., Brinkman, A., and Zwarthoff, E. C. (1992). Structural aspects of the IGFBP family. Growth Regul. 2,69-70.
89. 35S-sulphate uptake by mammalian insulin-like growth factors I and II in cultured cartilages of the Japanese eel, in cultured cartilages of the Japanese eel, Anguilla japonica. J. Exp. Zool. 256, 347-350.
90. Duan C., and Hirano, T. (1992). Effects of insulin-like growth factor 1 and insulin on the invitro uptake of sulphate by eel branchial cartilage: Evidence for the presence of independent hepatic and pancreatic sulphation factors. J. Endocrinol. 133, 211-219.
91. 33S]sulfate by ceratobranchial cartilages of the Japanese eel, Angidlla japonica. Gen. Comp. Endocrmol. 79, 320-325.
92. Duan C., and Plisetskaya, E. M. (1993). Nutritional regulation of insulin-like growth factor-I mRNA expression in salmon tissues. J. Endocrinol. 139, 243-252.
93. Duan, C., Duguay, S. J., and Plisetskaya, E. M. (1993). Insulin-like growth factor (IGF-I) mRNA expression in coho salmon, Oncorhynclnis kisutsch. Tissue distribution and effects of growth hormone/prolactin family proteins. Fish Physiol. Biochem. 11, 371-379.
94. Duan, C., Duguay, S. J., Swanson, P., Dickhoff, W. A., and Plisetskaya, E. M. (1994). Tissue-specific expression of insulin-like growth factor I messenger ribonucleic acids in salmonids: Developmental, hormonal, and nutritional regulation. In "Perspectives in Comparative Endocrinology" (K. G. Davey, S. S. Tobe, and D. E. Peter, eds.) pp. 365-372. National Research Council of Canada, Toronto.
95. Duan, C., Plisetskaya, E. M., and Dickhoff, W. W. (1995). Expression of insulin-like growth factor I in normally and abnormally developing coho salmon (Cncorhynchus kisutch). Endocrinology 136, 446-452.
96. Duguay, S. J., Park, L. K., Samadpour, M., and Dickhoff, W. W. (1992). Nucleotide sequence and tissue distribution of three insulin-like growth factor I prohormones in salmon. Mol. Endocrinol. 6, 1202-1210.
97. Duguay, S. J., Swanson, P., and Dickhoff, W. W. (1994). Differential expression and hormonal regulation of alternatively spliced IGF-I mRNA transcripts in salmon. J. Mol. Endocrinol. 12, 25-37.
98. Duguay, S. J., Chan, S. J., Mommsen, T. P., and Steiner, D. F. (1995). Divergence of insulin-like growth factors I and II in the elasmobranch Sqiialns acantliias. FEBS Lett. 371,69-72.
99. Duguay, S. J., Lai-Zhang, J., Steiner D. F., Funkenstein, B., and Chan, S. J. (1996). Developmental and tissue-regulated expression of IGF-I and IGF-II mRNAs in Sparus aurata. J. Mol. Endocrinol. 16, 123-132.
100. Dulak, N. C., and Temin, H. M. (1973). Multiplication-stimulating activity for chicken embryo fibroblasts from rat liver cell conditioned medium: A family of small peptides. J. Cell. Physiol. 81, 161-170.
101. Ebberink, R. H. M., Smith, A. B., and van Minnen, J. (1989). The insulin family. Evolution of structure and function in vertebrates and invertebrates. Biol. Bull. 177, 176-182.
102. Ehrenborg, E. (1994). "Genetic Characterization of Human Insulin-like Growth Factor Binding Proteins." Ph.D. thesis. Karolinska Institute, Stockholm.
103. Eizirik, D. L., Skottner, A., and Hellerström, G (1995). Insulin-like growth factor I does not inhibit secretion in adult human pancreatic islets in tissue culture. Eur. J. Endocrinol. 133, 248-250.
104. Elgar, G., Sandford, R., Aparicio, S., Macrae, A., Venkatesh, B., and Brenner, S. (1996). Small is beautiful - Comparative genomics with the pufferfish. Trends Genet. 12,145-150.
105. el-Roeiy, A., Chen, X., Roberts, V. J., Shimasakai, S., Ling, N., LeRoith, D., Roberts, C. T., Jr., and Yen, S. S. (1994). Expression of the genes encoding the insulin-like growth factors (IGF-I and IGF-II), the IGF and insulin receptors, and IGF-binding proteins-1-6 and the localization of their gene products in normal and polycsytic ovary syndrome ovaries. J. Clin. Endocrinol. Metab. 78, 1488-1496.
106. Eriksen, E. F., Kassem, M., and Langdahl, B. (1996). Growth hormone, insulin-like growth factors and bone remodelling. Eur. J. Clin. Invest. 26, 525-534.
107. Falkmer, S. (1995). Origin of the parenchymal cells of the endocrine pancreas. Some phylogenetic and ontogenetic aspects. In "Frontiers of Gastrointestinal Research 23" (M. Mignon and R. T. Jensen, eds.), pp. 2-29. Karger Verlag, Basel.
108. Fehmann, H. C., Jehle, P., Markus, U., and Goke, B. (1996). Functional active receptors for insulin-like growth factor-I (IGF-I and IGF-II on insulin-, glucagon-, and somatostatin-producing cells. Metabol. Clin. Exp. 45, 759-766.
109. Flier, J. S., Usher, P., and Moses, A. C. (1986). Monoclonal antibody to the type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis, clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblasts. Proc. Natl. Acad. Sci. USA 83, 664-668.
110. Flyvberg, A., and Ørskov, H. (1994). Insulin-like growth factors and the kidney. In "The Insulin-like Growth Factors and Their Regulatory Proteins" (R. C. Baxter, P. D. Gluckman, and R. G. Rosenfeld, eds.), pp. 417-425. Elsevier, Amsterdam/New York.
111. Frade, J. M., Marti, E., Bovolenta, P., Rodriguez-Pena, M. A., Pérez-Garcia, Rohrer, H., Edgar, D., and Rodriguez-TÉbar, A. (1996). Insulin-like growth factor-I stimulates neurogenesis in chick retina by regulating expression of the a6 integrin subunit. Development 122,2497-2506.
112. Frattali, A. L., Treadway, J. L., and Pessin, J. E. (1992). Transmembrane signalling by the human insulin receptor kinase. J. Biol. Chem. 267, 19521-19528.
113. Froesch, E. R., and Zapf, J. (1985). Insulin-like growth factors and insulin: Comparative aspects. Diabetologica 28, 485-493.
114. Froesch, E. R., Burgi, H., Ramseier, E. B., Bally, P., and Labhart, A. (1963). Antibody suppressible and non-suppressible insulin-like activities in human serum and their physiological significance. J. Clin. Invest. 42, 1816-1834.
115. Fukazawa, Y., Siharath, K., Iguchi, T., and Bern, H. A. (1995). In vitro secretion of insulin-like growth factor-binding proteins from liver of striped bass, Morone saxatilis. Gen. Comp. Endocrinol. 99, 239-247.
116. Funkenstein, B., Sibergeld, A., Cavari, B., and Laron, Z. (1989). Growth hormone increases plasma levels of insulin-like growth factor (IGF-I) in a teleost, the gilthead seabream, Spants aurata. J. Endocrinol. 120, R19-R21.
117. Garcia-Fernandez, J., and Holland, P. W. H. (1994). Archetypal organisation of the amphioxus Hox gene cluster. Nature 370, 563-566.
118. Germain-Lee, E. L., Janicot, M., Lammers, R., Ullrich, A., and Casells, S. J. (1992). Expression of a type I insulin-like growth factor receptor with low affinity for insulin-like growth factor II. Biochem. J. 281, 413-417.
119. Gluckman, P. D., Guan, J., Beilharz, E. J., Klempt, N. D., Miller, O., Sirimanne, E., Dragunow, M., and Williams, C. E. (1993). The role of the insulin-like growth factor system in neuronal rescue. Ann. NY Acad. Sci. 692, 138-148.
120. Gockerman, A., Prevelte, T., Jones, J. I., and Clemmons, D. R. (1995). Insulin-like growth factor (IGF)-binding proteins inhibit the smooth muscle cell migration responses to IGF-I and IGF-II. Endocrinology 136, 4168-4173.
121. Gray, E. S., and Kelley, K. M. (1991). Growth regulation in the gobiid teleost, Gillichthys mirabilis: Roles of growth hormone, hepatic growth hormone receptors and insulin-like growth factor I. J. Endocrinol. 131, 57-66.
122. Gray, E. S., Kelley, K. M., Law, S., Tsai, R., Young, G., and Bern, H. (1992). Regulation of hepatic growth hormone receptors in coho salomn (Oncorhynchus kisutch). Gen. Comp. Endocrinol. 88, 243-252.
123. Gröne, H.-J., Neumann, P., and Fuchs, E. (1992). Localization and characterization of IGF-I receptors in fetal and adult human kidneys. Miner. Electrolyte Metab. 18, 256-263.
124. Guillette, L. J., Cox, M. C., and Crain, D. A. (1997). Plasma insulin-like growth factor-I concentration during the reproductive cycle of the American alligator (Alligator mississipiensis). Gen. Comp. Endocrinol. 104, 116-122.
125. Guler, H. P., Schmid, C., Zapf, J., and Froesch, E. R. (1989). Effects of recombinant insulin-like growth factor I on insulin secretion and renal function in normal human subjects. Proc. Natl. Acad. Sci. USA 86, 2868-2872.
126. Gustafson, T. A., and Rutter, W. J. (1990). The cysteine-rich domains of the insulin and insulin-like growth factor I receptors are primary determinants of hormone binding specificity. J. Biol. Chem. 265, 18663-18667.
127. Guttiérrez, J., Parrizas, M., Carneiro, N., Maestro, J. L., Maestro, M. A., and Planas, J. (1993). Insulin and IGF-I receptors and tyrosine kinase activity in carp ovaries: Changes with reproductive cycle. Fish Physiol. Biochem. 11, 247-254.
128. Hagiwara, S., Sakurai, T., Tashiro, F., Hashimoto, Y., Matsuda, Y., Nonomura, Y., and Miyazaki, J. (1995). An inhibitory role for phosphatidylinositol 3-kinase in insulin secretion from pancreatic B cell line MIN6. Biochem. Biophys. Res. Commun. 214, 51-59.
129. Hainaut, P., Kowalski, A., Giorgetti, S., Baron, V., and Van Obberghen, E. (1991). Insulin and insulin-like-growth-factor I (IGF-I) receptors in Xenopus laevis oocytes. Biochem. J. 273, 673-678.
130. Hammerman, M. R. (1991). The renal growth hormone/insulin-like growth factor I axis. Am. J. Kidney Dis. 6, 644-646.
131. Han, V. K. M., D'Ercole, A. J., and Lund, P. K. (1987a). Cellular localization of somatomedin (insulin-like growth factor) messenger RNA in the human fetus. Science 236, 193-197.
132. Han, V. K. M., Hill, D. J., Strain, A. J., Towle, A. C., Lauder, J. M., Underwood, L. E., and D'Ercole, A. J. (1987b). Identification of somatomedin/insulin-like growth factor immunoreactive cells in the human fetus. Pediatr. Res. 22, 245-249.
133. Hansson, H.-A., Nilsson, A., Isgaard, J., Billig, H., Isaksson, O., Skottner, A., Andersson, I. K., and Rozell, B. (1988). Immunohistochemical localization of insulin-like growth factor I in the adult rat. Histochemistry 89, 403-410.
134. Haselbacher, G., Schwab, M. E., Pasi, A., and Humbel, R. E. (1985). Insulin-like growth factor II (IGF-II) in human brain: Regional distribution of IGF-II and higher molecular mass forms. Proc. Natl. Acad. Sci. USA 82, 2153-2157.
135. Halt, P. J., Liebon, C., Moriniere, M., Oberlander, H., and Porcheron, P. (1997). Activity of insulin growth factors and shrimp neurosecretory organ extracts on a lepidopteran cell line. Arch. Insect Biochem. Physiol. 34, 313-328.
136. Hepler, J. E., and Lund, P. K. (1990). Molecular biology of the insulin-like growth factors. Relevance to nervous system function. Mol. Neurobiol. 4, 93-127.
137. Hernandez, E. R. (1995). Regulation of the genes for insulin-like growth factor (IGF) I and II and their receptors by steroids and gonadotropins in the ovary. J. Steroid Biochem. Mol. Biol. 53, 219-221.
138. Hernandez-Sanchez, C., Lopez-Carranza, A., Alarcon, C., de la Rosa, E. J., and de Pablo, F. (1995). Autocrine/paracrine role of insulin-related growth factors in neurogenesis: Local expression and effects on cell proliferation and differentiation in retina. Proc. Natl. Acad. Sci. USA 92, 9834-9838.
139. Hetru, C., Li, K. W., Bulet, P., Lagueux, M., and Hoffmann, J. A. (1991). Isolation and structural characterization of an insulin-related molecule, a predominant neuropeptide from Locusta migratoria. Eur. J. Biochem. 201, 495-499.
140. Hietter, H., Van Dorsselaer, A., Green, B., Denoroy, L., Hoffmann, J., and Luu, B. (1990). Isolation and structure elucidation of a novel 5-kDa peptide from neurohaemal lobes of the corpora cardiaca of Locusta migratoria (Insecta, Orthoptera). Eur. J. Biochem. 187, 241-247.
141. Hill, D. J., and Hogg, J. (1991). Growth factor control of pancreatic B cell hyperplasia. Bailliere's Clin. Endocrinol. Metab. 5, 689-698.
142. Hill, D. J., Frazer, A., Swenne, I., and Milner, R. D. (1987). Somatomedin-C in human fetal pancreas. Cellular localization and release during organ culture. Diabetes 36, 465-471.
143. Hirschberg, R. (1994). The physiology and pathophysiology of IGF-I in the kidney. In "Current Directions in Insulin-like Growth Factor Research" (D. LeRoith and M. K. Raizada, eds.), pp. 345-366. Plenum, New York.
144. Hirschberg, R. (1996). Insulin-like growth factor I in the kidney. Miner. Electrolyte Metab. 22, 128-132.
145. Hogg, J., Hill, D. J., and Han, V. K. (1994). The ontogeny of insulin-like growth factor (IGF) and IGF-binding protein gene expression in the rat pancreas. J. Mol. Endocrinol. 13,49-58.
146. Holland, P. W. H., Garcia-Fernandez, J., Williams, N. A., and Sidow, A. (1994). Gene duplications and the origins of vertebrate development. Development 1994 Suppl. 125-133.
147. Holzenberger, M., Lapointe, F., Leibovici, M., and Lievre, C. C. (1996). The avian IGF type 1 receptor: cDNA analysis and in situ hybridization reveal conserved sequence elements and expression patterns relevant for the development of the nervous system. Brain Res. Dev. Brain Res. 97, 76-87.
148. Höög, A., Grimelius, L., Falkmer, S., and Sara, V. R. (1993). A high-molecular IGF-2-immunoreactive peptide (pro-IGF-2?) in the insulin cells of the islets of Langerhans of man and rat. Regul. Pept. 47, 275-283.
149. Hoppener, J. W., de Pagter-Holthuizen, P., Geurts van Kessel, A. H. M., Jansen, M., Kittur, S. D., Antonarakis, S. E., Lips, C. J. M., and Sussenbach, J. S. (1985). The human gene encoding insulin-like growth factor I is located on chromosome 12. Hum. Genet. 69,157-160.
150. Humbel, R. E. (1990). Insulin-like growth factors I and II. Eur. J. Biochem. 190, 445-462.
151. Hynes, M. A., Brooks, P. J., Van Wyke, J. J., and Lund, P. K. (1988). Insulin-like growth factor II messenger ribonucleic acids are synthesized in the choroid plexus of the rat brain. Mol. Endocrinol. 2, 47-54.
152. Isaksson, O. G. P., Nilsson, A., Isgaard, J., and Lindahl, A. (1990). Cartilage as a target tissue for growth hormone and insulin-like growth factor I. Acta Paediatr. Scand. Suppl. 367, 137-141.
153. Isaksson, O. G. P., Ohlsson, C., Nilsson, A., Isgaard, J., and Lindahl, A. (1991). Regulation of cartilage growth by growth hormone and insulin-like growth factor I. Pediatr. Nephrol. 5, 451-453.
154. 35S]sulphate by Xenopus cartilage: The influence of growth hormone and prolactin. Zool. Sci. 1, 609-615.
155. Ishizaki, H., Mizoguchi, A., Fujishita, M., Suzuki, A., Moriya, I., O'oka, H., Kataoka, H., Isogai, A., Nagasawa, H., Tamura, S., and Suzuki, A. (1983). Species specificity of the insect prothoracicotropic hormone (PTTH): The presence of Bombyx- and Samia-specific PTTHs in the brain of Bombyx mori. Dev. Growth Differ. 25, 593-600.
156. Iwami, M., Furuya, I., and Kataoka, H. (1996a). Bombyxin-related peptides: cDNA structure and expression in the brain of the hornworm Agrius convoluvidi. Insect. Biochem. Mol. Biol. 26, 25-32.
157. Iwami, M., Tanaka, A., Hano, N., and Sakurai, S. (1996b). Bombyxin gene expression in tissues other than brain detected by reverse transcription polymerase chain reaction (RT-PCR) and in-situ hybridization. Experientia 52, 882-887.
158. James, P. L., Jones, S. B., Busby, W. H., Clemmons, D. R., and Rotwein, P. (1993). A highly-conserved insulin-like growth factor-binding protein (IGFBP-5) is expressed during myoblast differentiation. J. Biol. Chem. 268, 22305-22312.
159. Janicot, M., Flores-Riveros, J. R., and Lane, M. D. (1991). The insulin-like growth factor 1 (IGF-1) receptor is responsible for mediating the effects of insulin, IGF-1, and IGF-2 in Xenopus laevis oocytes. J. Biol. Chem. 266, 9382-9391.
160. Jansen, M., van Schaik, F. M., Ricker, T., Bullock, B., Woods, D. E., Gabbay, K. H., Nussbaum, A. L., Sussenbach, J. S., and Van den Brande, J. L. (1983). Sequence of cDNA encoding human insulin-like growth factor I precursor. Nature 306, 609-611.
161. Jansen, M., van Schaik, F. M. A., van Toi, H., Van den Brande, J. L., and Sussenbach, J. S. (1985). Nucleotide sequences of cDNAs encoding precursors of human insulin-like growth factor II (IGF-II) and an IGF-II variant. FEBS Lett. 179, 243-246.
162. Jhun, B. H., Rose, D. W., Seely, B. L., Rameh, L., Cantley, L., Saltiel, A. R., and Olefsky, J. M. (1994). Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidyl-inositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression. Mol. Cell. Biol. 14, 7466-7475.
163. Jones, J. I., and Clemmons, D. R. (1995). Insulin-like growth factors and their binding proteins: Biological actions. Endocr. Rev. 16, 3-34.
164. Jones, J. I., Gockerman, A., Busby, W. H., Wright, G., and Clemmons, D. R. (1993). Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the 5 1 integrin by means of its Arg-Gly-Asp sequence. Proc. Natl. Acad. Sci. USA 90, 10553-10557.
165. Kaaawa, H., Kobayashi, M., Hasegawa, Y., and Aida, K. (1994). Insulin and insulin-like growth factors I and II induce final maturation of oocytes of red seabream, Pagrns major, in vitro. Gen. Comp. Endocrinol. 95, 293-300.
166. Kagawa, H., Moriyama, S., and Kawauchi, H. (1995). Immunocytochemical localization of IGF-I in the ovary of the red seabream, Pagrus major. Gen. Comp. Endocrinol. 99,307-315.
167. Kajimoto, Y., and Rotwein, P. (1989). Structure and expression of a chicken insulin-like growth factor I precursor. Mol. Endocrinol. 3, 1907-1913.
168. Kajimoto, Y., and Rotwein, P. (1990). Evolution of insulin-like growth factor I (IGF-I): Structure and expression of an IGF-I precursor from Xenopns laevis. Mol. Endocrinol. 4, 217-226.
169. Kajimoto, Y., and Rotwein, P. (1991). Structure of the chicken insulin-like growth factor I gene reveals conserved promotor elements. J. Biol. Chem. 266, 9724-9731.
170. Kato, M. V., Sato, H., Tsukada, T., Ikawa, Y., Aizawa, S., and Nagayoshi, M. (1996). A follistatin-Iike gene, mac25, may act as a growth suppressor of osteosarcoma cells. Oncogene 12, 1361-1364.
171. Kavsan, V. M., Koval, A. P., Grebenjuk, V. A., Chan, S. J., Steiner, D. F., Roberts C. T., Jr., and Le Roith, D. (1993). Structure of the chum salmon insulin-like growth factor I gene. DNA Cell Biol. 12, 729-737.
172. Kavsan, V. M., Grebenjuk, V. A., Koval, A. P., Skorokhod, A. S., Roberts C. T., Jr., and Le Roith, D. (1994). Isolation of a second non-allelic insulin-like growth factor I gene from the salmon genome. DNA Cell Biol. 13, 555-559.
173. Kawai, K., Suzuki, S., Takano, K., Hizuka, N., Watanabe, Y., and Yamashita, K. (1990). Effects of insulin-like growth factor-I on insulin and glucagon release from isolated perfused rat pancreas. Endocrinol. Jpn. 37, 867-874.
174. Kawakami, A., Iwami, M., Nagasawa, H., Suzuki, A., and Ishizaki, H. (1989). Structure and organization of four clustered genes that encode bombyxin, an insulin-related brain secretory peptide of the silkmoth Bombyx mon. Proc. Natl. Acad. Sci. USA 86, 6843-6847.
175. Kelley, K. M., Siharath, K., and Bern, H. A. (1992). Identification of insulin-like growth factor-binding proteins in the circulation of four teleost fish species. J. Exp. Zool. 263, 220-224.
176. Kelley, K. M., Gray, E. S., Siharath, K., and Bern, H. A. (1993). Experimental diabetes mellitus in a teleost fish. II. Roles of insulin, growth hormone (GH), insulin-like growth factor-I, and hepatic GH receptors in diabetic growth inhibition in the goby, Giltichthys mirabilis. Endocrinology 132, 2696-2702.
177. Kelley, K. M., Oh, Y., Gargorsky, S. E., Gucey, Z., Matsumoto, T., Hwa, V., Ng, L., Simpson, D. M., and Rosenfeld, R. G. (1996). Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics. Int. J. Biochem. Cell Biol. 28, 619-637.
178. Kikuchi, K., Buonomo, F. C, Kajimoto, Y., and Rotwein, P. (1991). Expression of insulin-like growth factor-I during chicken development. Endocrinology 128, 1323-1328.
179. Kimura-Kawakami, M., Iwami, M., Kawakami, A., Nagasawa, H., Suzuki, A., and Ishizaki, H. (1992). Structure and expression of bombyxin-related peptide genes of the moth Samia cynthia ricini. Gen. Comp. Endocrinol. 86, 257-268.
180. Kinhult, A. (1994). Barramundi (Lates calcarifer) IGF-I: Characterization of cDNA, genomic sequence, and regulation of mRNA expression. Ph.D. Thesis, Queensland University of Technology, Brisbane, Australia.
181. Kita, K., Tomas, F. M., Owens, P. C., Knowles, S. E., Forbes, B. E., Upton, Z., Hughes, R., and Ballard, F. J. (1996). Influence of nutrition on hepatic IGF-I mRNA levels and plasma concentrations of IGF-I and IGF-II in meat-type chicken. J. Endocrinol. 149, 181-190.
182. Kittur, S., Hoppener, J. W. M., Antonarakanis, S. E., Daniels, J. D. J., Meyers, D. A., Maestri, N. E., Jansen, M., Korneluk, R. G., Nelkin, B. D., and Kazazian, H. H., Jr. (1985). Linkage map of the short arm of human chromosome 11, Location of the genes for catalase, calcitonin, and insulin-like growth factor. Proc. Natl. Acad. Sci. USA 82, 5064-5067.
183. Komourdjian, M. P., and Idler, D. R. (1978). Hepatic mediation of hormonal and nutritional factors influencing the in vitro sulfur uptake by rainbow trout bone. Gen. Comp. Endocrinol. 36, 33-39.
184. Kornfeld, S. (1992). Structure and function of the mannose-6-phosphate/insulin-like growth factor II receptors. Annu. Rev. Biochem. 61, 307-330.
185. Kou, K., James, P. L., Clemmons, D. R., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., and Rotwein, P. (1994a). Identification of two clusters of mouse insulin-like growth factor binding protein genes on chromosomes 1 and 11. Genomics 21, 653-655.
186. Kou, K., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., and Rotwein, P. (1994b). Organisation, expression and chromosomal location of the mouse insulin-like growth factor binding protein 5 gene. Genomics 20, 412-418.
187. Krieg, R. J., Santos, F., and Chan, J. C. M. (1995). Growth hormone, insulin-like growth factor and the kidney. Kidney Int. 48, 321-336.
188. Lagueux, M., Lwoff, L., Meister, M., Goltzené, F., and Hoffmann, J. A. (1990). cDNAs from neurosecretory cells of brains of Locusta migratoria (Insecta, Orthoptera) encoding a novel member of the superfamily of insulins. Eur. J. Biochem. 187, 249-254.
189. Lau, M. M. H., Stewart, C. E. H., Liu, Z., Bhatt, H., Rotwein, P., and Stewart, C. L. (1994). Loss of imprinted IGF2/cation-independent mannose-6-phosphate receptor results in fetal overgrowth and perinatal lethality. Genes Dev. 8, 2953-2963.
190. Leahy, J. L., and Vandekerkhove, K. M. (1990). Insulin-like growth factor-I at physiological concentrations is a potent inhibitor of insulin secretion. Endocrinology 126, 1593-1598.
191. Ledley, F. D., DiLella, A. G., Kwok, S. C., and Woo. S. L. (1985). Homology between phenylalanine and tyrosine hydroxylases reveals common structural and functional domains. Biochemistry 24, 3389-3394.
192. Lee, W.-H., Michels, K. M., and Bondy, C. A. (1993). Localization of insulin-like growth factor binding protein-2 messenger RNA during postnatal brain development: Correlation with insulin-like growth factors I and II. Neuroscience 53, 251-265.
193. Leeuwenberg, B. R., Hudson, N. L., Moore, I. G., Hurst, P. R., and McNatty, K. P. (1996). Peripheral and ovarian IGF-I concentrations during the ovine oestrous cycle. J. Endocrinol. 148, 281-289.
194. Le Gac, F., Ollitrault, M., Loir, M., and Le Bail, P.-Y. (1992). Evidence for binding and action of growth hormone in trout testis. Biol. Reprod. 46, 949-957.
195. Le Gac, F., Loir, M., Le Bail, P.-Y., and Ollitrault, M. (1996). Insulin-like growth factor I (IGF-I) mRNA and IGF-I receptor in trout testis and in isolated spermatogenic and Sertoli cells. Mol. Reprod. Dev. 44, 23-35.
196. Leibush, B., Parrizas, M., Navarro, I., Lappova, Y., Maestro, M. A., Encinas, M., Plisetskaya, E. M., and Gutiérrez, J. (1996). Insulin and insulin-like growth factor-I receptors in fish brain. Regul. Pept. 61, 155-161.
197. Leong, S. R., Baxter, R. C., Camerato, T., Dai, J., and Wood, W. I. (1992). Structure and functional expression of the acid-labile subunit of the insulin-like growth factor binding protein complex. Mol. Endocrinol. 6, 870-876.
198. LeRoith, D. (1997). Insulin-like growth factors. N. Engl. J. Med. 336, 633-640.
199. LeRoith, D., Adamo, M., Werner, H., and Roberts, C. T., Jr. (1991). Insulin-like growth factors and their receptors as regulators in normal physiology and pathologic states. Trends Electron Microsc. 2, 134-139.
200. Levy, M. J., Hernandez, E. R., Adashi, E. Y., Stillman, R. J., Roberts C. T., Jr., and LeRoith, D. (1992). Expression of the insulin-like growth factor (IGF)-I and -II and the IGF-I and -II receptor genes during postnatal development of the rat ovary. Endocrinology 131,1202-1206.
201. Li K. W., and Geraerts, W. P. M. (1992). Isolation and chemical characterization of a novel insulin-related neuropeptide from the freshwater snail, Lymnaea stagnaus. Eur. J. Biochem. 205, 675-678.
202. Loffing-Cueni, D., Schmid, A., Graf, H., and Reinecke, M. (1998). IGF-I in the bony fish Coitus scorpins: cDNA, expression and differential localization in brain and islets. Molec. Cell. Endocrinol. (in press).
203. Lowe, W. L., Lasky, S. R., LeRoith, D., and Roberts, C. T., Jr. (1988). Distribution and regulation of rat insulin-like growth factor I messenger ribonucleic acids encoding alternative carboxyterminal E-peptides, evidence for differential processing and regulation in liver. Mol. Endocrinol. 2, 528-535.
204. Lu-Kuo, J., Ward, D. C., and Spritz, R. A. (1993). Fluoresence in situ hybridisation mapping of 25 markers on distal human chromosome 2q surrounding human Waardenburg syndrome, type I (WS1) locus (PAX3 gene). Genomics 16, 173-179.
205. Lund, P. K. (1994). Insulin-like growth factor I: Molecular biology and relevance to tissue specific expression and action. Recent Prog. Harm. Res. 49, 125-148.
206. Lund, P. K., Moats-Staats, B. M., Hynes, M. A., Simmons, J. G., Jansen, M., D'Ercole, A. J., and Van Wyk, J. J. (1986). SomatomedinC/insuIin-like growth factor-I and insulin-like growth factor-II mRNAs in rat fetal and adult tissues. J. Biol. Chem. 261, 14539-14544.
207. Lundin. L. (1993). Evolution of the vertebrate genome as reflected in paralogous chromosomal regions in man and the house mouse. Genomics 16, 1-19.
208. Luyten, F. P., Hascall, V. C., Nissley, S. P., Morales, T. L., and Reddi, A. H. (1988). IGFs maintain steady state metabolism of proteoglycans in bovine cartilage explants. Arch. Biochem. Biophys. 267, 416-425.
209. Maake, C., and Reinecke, M. (1993). Immunohistochemical localization of insulin-like growth factor 1 and 2 in the endocrine pancreas of rat, dog and man and their coexistence with classical islet hormones. Cell Tissue Res. 273, 249-259.
210. MacDonald, R. G., Pfeffer, M. A., Coussens, L., Tepper, M. A., Brocklebank, C. M., Mole, J. E., Anderson, J. K., Chen, E., Czech, M. P., and Ullrich, A. (1988). A single receptor binds both insulin-like growth factor and mannose-6-phosphate. Science 239, 1134-1137.
211. Mack, A. F., Bait, S. L., Fernald, R. D. (1995). Localization and expression of insulin-like growth factor in the teleost retina. Visual Neurosci. 12, 457-461.
212. +-ATPase in coho salmon, Oncorhynchus kisutch. J. Endocrinol. 138, 23-30.
213. Margot, J. B., Binkert, C., Mary, J. L., Landwehr, J., Heinrich, G., and Schwander, J. (1989). A low molecular weight insulin-like growth factor binding protein from rat, cDNA cloning and tissue distribution of its messenger RNA. Mol. Endocrinol. 3, 1053-1060.
214. Mason, H. D., Cwyfan-Hughes, S. C., Heinrich, G., Franks, S., and Holly, J. M. (1996). Insulin-like growth factor (IGF) I and II, IGF-binding proteins, and IGF-binding protein proteases are produced by theca and stroma of normal and polycystic human ovaries. J. Clin. Endocrinol. Metab. 81, 276-284.
215. Massaque, J., and Czech, M. P. (1982). The subunit structures of two distinct receptors for insulin-like growth factors 1 and 2 and their relationship to the insulin receptor. J. Biol. Chem. 257, 5038-5046.
216. Matejka, G. L., and Jennische, E. (1992). IGF-I binding and IGF-I mRNA expression in the post-ischemic regenerating rat kidney. Kidney Int. 42, 1113-1123.
217. Matejka, G. L., Eriksson, P. S., Carlsson, B., and Jennische, E. (1992). Distribution of IGF-I mRNA and IGF-I binding sites in the rat kidney. Histochemistry 97, 173-180.
218. Mathews, L. S., Norstedt, G., and Palmiter, R. D. (1986). Regulation of insulin-like growth factor I gene expression by growth hormone. Proc. Natl. Acad. Sci. USA 83, 9343-9347.
219. Mauras, N., Rogol, A. D., Haymond, M. W., and Veldhuis. J. D. (1996). Sex steroids, growth hormone, insulin-like growth factor-1-Neuroendocrine and metabolic regulation in puberty, Horm. Res. 45, 74-80.
220. McCarthy, T. L., Centrella, M., and Canalis, E. (1989). Parathoroid hormone enhances the transcript and polypeptide levels of insulin-like growth factor I in osteoblast-enriched cultures from fetal rat bone. Endocrinology 12-4, 1247-1253.
221. McCormick, S. D., Sakamoto, T., Hasegawa, S., and Hirano, T. (1991). Osmoregulatory actions of insulin-like growth factor-I in rainbow trout (Oncorhynchus mykiss). J. Endocrinol. 130, 87-92.
222. McCormick, S. D., Kelly, K. M., Young, G., Nishioka, R. S., and Bern, H. A. (1992a). Stimulation of coho salmon growth by insulin-like growth factor I. Gen. Com. Endocrinol. 86, 398-406.
223. McCormick, S. D., Tsai, P. I., Kelly, K. M., Nishioka, R. S., and Bern, H. A. (1992b). Hormonal control of sulfate uptake by branchial cartilage of coho salmon: Role of IGF-I. J Exp. Zool. 262, 166-171.
224. McFarland, D. C. Ferrin, N. H., Gilkerson, K. K., and Pesall, J. E. (1992). Tissue distribution of insulin-like growth factor receptors in the turkey. Com. Biochem. Physiol. B 103, 601-607.
225. McRory, J. E., and Sherwood, N. M. (1994). Catfish expresses two forms of insulin-like growth factor-I (IGF-I) in the brain. J. Biol. Chem. 269, 18588-18592.
226. Meester, I., Ramkema, M. D., van Minnen, J., and Boer, H. H. (1992). Differential expression of four genes encoding molluscan insulin-related peptides in the central nervous system of the pond snail Lymnaea stagnalis. Cell Tissue Res. 269, 183-188.
227. Melmed, S., Yamashita, S., Yamasaki, H., Fagin, J., Namba, H., Yamamoto, H., Weber, M., Morita, S., Webster, J., and Prager, D. (1996). IGF-I receptor signalling: Lessons from the somatotroph. Recent Prog. Harm. Res. 51, 189-215.
228. Miettinen, P. J., Otonkoski, T., and Voutilainen, R. (1993). Insulin-like growth factor-II and transforming growth factor-alpha in developing human fetal pancreatic islets. J. Endocrinol. 138, 127-136.
229. Mohan, S., and Baylink, D. J. (1990). Autocrine-paracrine aspects of bone metabolism. Growth Genet. Horm. 6, 1-9.
230. Monget, P., and Monniaux, D. (1995). Growth factors and the control of folliculogenesis. J. Reprod. Fertil. Suppl. 49, 321-333.
231. Moore, A., and Morris, I. D. (1993). The involvement of insulin-like growth factor-I in local control of steroidogenesis and DNA synthesis of Leydig and non-Leydig cells in the rat testicular interstitium. J. Endocrinol. 138, 107-114.
232. Moore, A., Chen, C.-L. C., Davis, J. R. E., and Morris, I. D. (1993). Insulin-like growth factor- I mRNA expression in the interstitial cells of the rat testis. J. Mol. Endocrinol. 11, 319-324.
233. Morgan, D. O., Edman, J. C., Standring, D. N., Fried, V. A., Smith, M. C., Roth, R. A., and Rutter, W. J. (1987). Insulin-like growth factor II receptor as a multifunctional binding protein. Nature 329, 301-307.
234. Moxham, C. P., Duronio, V., and Jacobs, S. (1989). Insulin-like growth factor I receptor b-subunit heterogeneity. J. Biol Chem. 264, 13238-13244.
235. Murphy, L. J., Bell, G. I., and Friesen, H. G. (1987). Tissue distribution of insulin-like growth factor I and II messenger ribonucleid acid in the adult rat. Endocrinology 120, 1279-1282.
236. Murphy, M., Pykett, M. J., Harnish, P., Zang K. D., and George, D. L. (1993). Identification and characterization of genes differentially expressed in meningiomas. Cell Growth Differ. 4, 715-722.
237. Myers, M. G., Jr., Backer, J. M., Sun, X. J., Shoelson, S., Hu, P., Schlessinger, J., Yoakim, M., Schaffhausen, B., and White, F. M. (1992). IRS-1 activates phosphatidylinositol 3′-kinase by associating with src homology 2 domains of p85. Proc. Natl. Acad. Sci. USA 89, 10350-10354.
238. Nagamatsu, S., Chan, S. J., Falkmer, S., and Steiner, D. F. (1991). Evolution of the insulin gene super family. Sequence of a preproinsulin-like growth factor cDNA from the Atlantic hagfish. J. Biol. Chem. 266, 2397-2402.
239. Nagasawa, H., Kataoka, H., Isogai, A., Tamura, S., Suzuki, A., Mizoguchi, A., Fujiwara, Y., Suzuki, A.,Takahashi, S. Y., and Ishizaki, H. (1986). Amino acid sequence of a prothoracicotropic hormone of the silkworm Bombyx mori. Proc. Natl. Acad. Sci. USA 83, 5840-5843.
240. Kelson, J. S. (1984). "Fishes of the World," 2nd Ed. Wiley, New York.
241. Nilsson, A., Isgaard, J., Lindahl, A., Dahlström, A., Skottner, A., and Isaksson, O. G. P. (1986). Regulation by growth hormone of number of chondrocytes containing IGF-I in rat growth plate. Science 233, 571-574.
242. Nilsson, C., Hultberg, B. M., and Gammeltoft, S. (1996). Autocrine role of insulin-like growth factor II secretion by rat choroid plexus. Eur. J. Neurosci. 8, 629-635.
243. Nissley, S. P., Kiess, W., and Sklar, M. M. (1991). The IGF-II/mannose-6-phosphate receptor. In "IGFs, Molecular and Cellular Aspects" (D. LeRoith, ed.), pp. 111-150. CRC Press, Boca Raton, FL.
244. Niu, P.-D., and Le Bail, P.-Y. (1993). Presence of insulin-like growth factor binding protein (IGF-BP) in rainbow trout (Oncorhynchus mykiss) serum. J. Exp. Zool. 265, 627-636.
245. Niu, P.-D., Perez-Sanchez, J., and Le Bail, P.-Y. (1993). Development of a protein binding assay for teleost insulin-like growth factor (IGF)-Iike: Relationship between growth hormone (GH) and IGF-like in the blood of the rainbow trout (Oncorhyncluis mykiss). Fish Pliysiol. Biocliem. 11, 1-6.
246. Oh, Y., Muller, H. L., Neely, E. K., Lamson, G., and Rosenfeld, R. G. (1993). New concepts in insulin-like growth factor receptor physiology. Growth Regul. 3, 113-123.
247. Oh, Y., Nagalla, S. R., Yamanaka, Y., Kim, H. S., Wilson, E., and Rosenfeld, R. G. (1996). Synthesis and characterization of insulin-like growth factor-binding protein (IGF-BP)-7. J. Biol. Chem. 271, 30322-30325.
248. Ohno, S. (1970). "Evolution by Gene Duplication." Springer-Verlag, Heidelberg.
249. Okada, T., Kawanom, Y., Sekakibara, T., Hazeki, O., and Ui, M. (1994). Essential role of PI-3 kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. J. Biol. Chem. 269, 3568-3573.
250. O'Malley, K. L., and Rotwein, P. (1988). Human tyrosine hydroxylase and insulin genes are contiguous on chromosome 11. Nucleic Acids Res. 16, 4437-4446.
251. Onagbesan, O. M., and Peddie, M. J. (1995). Effects of insulin-like growth factor I and interactions transforming growth factor a and LH on the proliferation of chicken granulosa cells and production of progesteron in culture. J. Reprod. Fertil. 104, 259-265.
252. O'Neill, I. E., Houston, B., and Goddard, C. (1990). Stimulation of insulin-like growth factor I production in primary cultures of chicken hepatocytes by chicken growth hormone. Mol. Cell. Endocrinol. 70, 41-47.
253. Palamarchuk, A. Y., Nektrutenko, A. Y., Gritzenko, O. B., and Kavsan, V. M. (1996). Organization and sequence of the chum salmon IGF-II gene. GenBank Accession No. X97225.
254. Pancak-Roessler, M. K., and Lee, P. D. K. (1990). Insulin-like growth factor-I and insulin-like growth factor-binding protein in the toad, Bufo woodhousei. Gen. Comp. Endocrinol. 78, 263-272.
255. Pardrigde, W. M. (1993). Transport of insulin-related peptides and glucose across the bloodbrain barrier. Ann. NY Acad. Sci. 692, 126-137.
256. Park, G. H., and Buetow, D. E. (1991). Genes for insulin-like growth factors I and I are expressed in senescent rat tissues. Gerontology 37, 310-316.
257. Pashmforoush, M., Chan, S. J., and Steiner, D. (1996). Structure and expression of the insulin-like peptide receptor from amphioxus. Mol. Endocrinol. 10, 857-866.
258. Pendelton, J. W., Nagai, B. K., Murtha, M. T., and Ruddle, F. H. (1993). Expansion of the Hox gene family and the evolution of chordates. Proc. Natl. Acad. Sci. USA 90,6300-6304.
259. Perez-Sanchez, J., Weil, C., Le Bail, P.-Y. (1992). Effects of human insulin-like growth factor-I on release of growth hormone by rainbow trout (Oncorhynchus mykiss) pituitary cells. J. Exp. Zool. 262, 287-290.
260. Perfetti, R., Scott, L. A., and Shuldiner, A. R. (1994). The two nonallelic insulin-like growth factor-I genes in Xenopus laevis are differentially regulated during development. Endocrinology 135, 2037-2044.
261. Perks, C. M., Denning-Kendall, P. A., Gilmour, R. S., and Wathes, D. C. (1995). Localization of messenger ribonucleic acids for insulin-like growth factor I (IGF-I), IGF-II and the type I IGF-I receptor in the ovine ovary throughout the oestrous cycle. Endocrinology 136, 5266-5273.
262. Plisetskaya, E. M. (19S9). Pancreatic peptides. In "The Comparative Physiology of Regulatory Peptides" (S. Holmgren, ed.), pp. 174-202. Chapman & Hall, London.
263. Plisetskaya, E. M., Bondareva, V. M., Duan, C., and Duguay, S. J. (1993). Does salmon brain produce insulin? Gen. Coinp. Endocrinol. 91, 74-80.
264. Quin, J. D. (1992). The insulin-like growth factors. Q. J. Med. 82, 81-90.
265. Rail, L. B., Scott, J., and Bell, G. I. (1987). Human insulin-like growth factor I and II messenger RNA: Isolation of complimentary DNA and analysis of expression. Methods Enzymol. 146, 239-248.
266. Ralphs, J. R., Wyle, L., and Hill, D. J. (1990). Distribution of insulin-like growth factor peptides in the developing chick embryo. Development 109, 51-58.
267. Rechler, M. M., and Brown, A. L. (1990). Insulin-like growth factor binding proteins, gene structure and expression. Growth Regul. 2, 55-68.
268. Reinecke, M. (1981). Immunohistochemical localization of polypeptide hormones in endocrine cells of the digestive tract of Brancliiostonm lanceolalwn. Cell Tissue Res. 219, 445-456.
269. Reinecke, M. (1997). Insulin-like growth factor I in bony fish. In "Neuroendocrinology. Retrospect and Perspectives" (H.-W. Korf and K.-H. Usadel, eds.), pp. 177-192. Springer Verlag, Berlin.
270. Reinecke, M., and Forssmann, W. G. (1984). Why do we study phylogeny of neuropeptidehormones? In "Evolution and Tumour Pathology of the Neuroendocrine System" (S. Falkmer, R. Hakanson, and F. Sundler, eds.), pp. 1-5. Elsevier, Amsterdam.
271. Reinecke, M., Drakenberg, K., Falkmer, S., and Sara, V. R. (1991). Presence of IGF-1-like peptides in the neuroendocrine system of the Atlantic Hagfish, Myxine glutinosa (Cyclostomata): Evidence derived by chromatography, radioimmunoassay and immunohistochemistry. Histochemistry 96, 191-196.
272. Reinecke, M., Drakenberg, K., Falkmer, S., and Sara, V. R. (1992). Peptides related to insulin-like growth factor 1 in the gastro-entero-pancreatic system of bony and cartilaginous fish. Regnl. Pept. 37, 155-165.
273. Reinecke, M., Betzler, D., Drakenberg, K., Falkmer, S., and Sara, V. R. (1993a). Occurrence of members of the insulin superfamily in central nervous system and digestive tract of protochordates. Histochemistry 99, 277-285.
274. Reinecke, M., Maake, C., Falkmer, S., and Sara, V. R. (1993b). The branching of insulin-like growth factor 1 and insulin: An immunohistochemical analysis during phylogeny. Regul. Pept. 48, 65-76.
275. Reinecke, M., Weimar, E., Maake, C., Drakenberg, K., Falkmer, S., and Sara, V. R. (1994). IGF-2-like peptides are present in insulin cells of the elasmobranchian endocrine pancreas: An immunohistochemical and Chromatographie study. Histochemistry 102, 365-371.
276. Reinecke, M., Broger, L., Brun, R., Zapf, J., and Maake, C. (1995). Immunohistochemical localization of insulin-like growth factor I and II in the endocrine pancreas of birds, reptiles and amphibia. Gen. Comp. Endocrinol. 100, 385-396.
277. Reinecke, M., Müller, C., and Segner, H. (1997a). An immunohistochemical analysis of the ontogeny, distribution and coexistence of 12 regulatory peptides and serotonin in endocrine cells and nerve fibers of the digestive tract of the turbot, Scophlhalimts maximus (Teleostei). Anat. Embryol. 195, 87-101.
278. Reinecke, M., Schmid, A., Ermatinger, R., and Loffing-Cueni, D. (1997b). Insulin-like growth factor I in the teleost Oreochromis mossambicus, the tilapia: Gene sequence, tissue expression and cellular localization. Endocrinology 138, 3613-3619.
279. Richardson, N. A., Anderson, A. J., Rimmer, M. A. and Sara, V. R. (1995). Localization of insulin-like growth factor-I immunoreactivity in larval and juvenile Barramundi (Lates calcarifer). Gen. Comp. Endocrinol. 100, 282-292.
280. Rinderknecht, E., and Humbel, R. E. (1976). Polypeptides with nonsupprcssible insulin-like and cell promoting activity in human serum: Isolation, chemical characterization and some biological properties. Proc. Natl. Acad. Sci. USA 73, 2365-2369.
281. Rinderknecht, E., and Humbel, R. E. (1978a). The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. J. Biol. Chem. 253, 2769-2776.
282. Rinderknecht, E., and Humbel, R. E. (1978b). Primary structure of human insulin-like growth factor II. FEBS Lett. 89, 283-286.
283. Roberts, C. T., Jr., Brown, A. L., Graham, D. E., Seelig, S., Berry, S., Gabbay, K. H., and Rechler, M. M. (1986). Growth hormone regulates the abundance of insulin like growth factor I RNA in adult rat liver. J. Biol. Chem. 261, 10025-10028.
284. Roberts, C. T., Jr., Lasky, S. R., Lowe, W. L., Jr., Seaman, W. T., and Le Roith, D. (1987a). Molecular cloning of rat insulin-like growth factor I complementary deoxyribonucleic acids, differential messenger ribonucleic acid processing and regulation by growth hormone in extrahepatic tissues. Mol. Endocrinol. 1, 243-248.
285. Roberts, C. T., Jr., Lasky, S. R., Lowe, W. L., Jr., Seaman, W. T., and Le Roith, D. (1987b). Rat IGF-I cDNA's contain multiple 5′-untranslated regions. Biocliein. Biophys. Res. Commun. 146, 1154-1159.
286. Roberts, R. D., Sharp, P. J., Burt, D. W., and Goddard, C. (1994). Insulin-like growth factor I in the ovary of the egg laying hen: Gene expression and biological actions on granulosa and theca cells. Gen. Comp. Endocrinol. 93, 327-336.
287. Romanus, J. A., Rabinovitch, A., and Rechter, M. W. (1985). Neonatal rat islet cell cultures synthesize insulin-like growth factor I. Diabetes 34, 696-702.
288. Romer, A. S. (1971). "The Vertebrate Body," 4th Ed. Saunders, Philadelphia.
289. Rosen, C. J., Donahue, L. R., and Hunter, S. J. (1994). Insulin-like growth factors and bone: The osteoporosis connection. Proc. Soc. Exp. Biol. Med. 206, 83-102.
290. Rosenfeld, R. G., Conover, C. A., Hodges, D., Lee, P. D., Misra, P., Hintz, R. L., and Li, C. H. (1987). Heterogeneity of insulin-like growth factor I affinity for the insulin-like growth factor II receptor: Comparison of natural, synthetic and recombinant DNA-derived insulinlike growth factor I. Biochem. Biophys. Res. Commun. 143, 199-205.
291. Rosselot, G., Reginato, A. M., and Leach, R. M. (1992). Development of a serum free system to study the effect of growth hormone and insulin-like growth factor-I on cultured postembryonic growth plate chondrocytes. In Vitro Cell. Dev. Biol. 28A, 235-244.
292. Rosselot, G., Vasilatos-Younken, R., and Leach, R. M. (1994). Effect of growth hgrmone, insulin-like growth factor I, basic fibroblast growth factor, and transforming growth factor on cell proliferation and proteoglycan synthesis by avian postembryonic growth plate chondrocytes. J. Bone Miner. Res. 9, 431-439.
293. Rosselot, G., McMurtry, J. P., Vasilatos-Younken, R., and Czerwinski, S. (1995). Effect of exogenous chicken growth hormone (cGH) administration on insulin-like growth factor-I (IGF-I) gene expression in domatic fowl. Mol. Cell. Endocrinol. 114, 157-166.
294. Roth, R. A. (1988). Structure of the receptor for insulin-like growth factor II: The puzzle amplified. Science 239, 1269-1271.
295. Roth, R. A., Steele-Perkins, G., Hari, J., Stover, C., Pierce, S., Turner, J., Edman, J. C., and Rutter, W. J. (1988). Insulin and insulin-like growth factor receptors and responses. Cold Spring Harbor Syntp. Quant. Biol. 53, 537-543.
296. Rotwein, P. (1986). Two insulin-like growth factor I messenger RNAs are expressed in human liver. Proc. Natl. Acad. Sci. USA 83, 77-81.
297. Rotwein, P. (1991). Structure, evolution, expression and regulation of insulin-like growth factors I and II. Growth Factors 5, 3-18.
298. Rotwein, P., and Hall, L. J. (1990). Evolution of insulin-like growth factor II: Characterization of the mouse IGF-I1 gene and identification of two pseudo-exons. DNA Cell Biol. 9, 725-735.
299. Rotwein, P., Pollock, K. M., Didier, D. K., and Krivi, G. G. (1986). Organization and sequence of the human insulin-like growth factor I gene: Alternative RNA processing produces two insulin-like growth factor I precursor peptides. J. Biol. Chem. 261, 4828-4832.
300. Rotwein, P., Folz, R. J., and Gordon, J. I. (1987). Biosynthesis of human insulin-like growth factor I (IGF-I). J. Biol. Chem. 262, 11807-11812.
301. Rotwein, P., Burgess, S. G., Milbrandt, J. D., and Krause, J. E. (1988). Differential expression of insulin-like growth factor genes in rat central nervous system. Proc. Natl. Acad. Sci. USA 85, 265-269.
302. Rotwein, P., Bichell, D. P., and Kikuchi, K. (1993). Multifactorial regulation of the IGF-I gene expression. Mol. Reprod. Dev. 35, 358-364.
303. Sakamoto, T., and Hirano, T. (1993). Expression of insulin-like growth factor I gene in osmoregulatory organs during seawater adaption of the salmonid fish: Possible mode of osmoregulatory action of growth hormone. Proc. Natl. Acad. Sci. USA 90, 1912-1916.
304. Salmon, W. D., and Daughaday, W. H. (1957). A hormonally controlled serum factor which stimulates sulphate incorporation by cartilage in vitro. J. Lab. Clin. Med. 49, 825-836.
305. Sara, V. R., and Hall, K. (1990). The insulin-like growth factors and their binding proteins. Physiol. Rev. 70, 591-614.
306. Sara, V. R., Uvnas-Moberg, K., Uvnas, B., Hall, K., Wetterberg, L., Posloncec, B., and Goiny, M. (1982). The distribution of somatomedins in the nervous system of the cat and their release following neural stimulation. Acta Physiol. Scand. 115, 467-470.
307. Sara, V. R., Carlsson-Skwirut, C., Andersson, C., Hall, E., Sjögren, B., Holmgren, A., and Jornvall, H. (1986). Characterization of somatomedins from human fetal brain: Identification of a variant form of insulin-like growth factor I. Proc. Natl. Acad. Sci. USA 83, 4904-4907.
308. Sara, V. R., Carlsson-Skwirut, C., Drakenberg, K., Giacobini, M. B., Hakanson, L., Mirmiran, M., Nordberg, A., Olson, L., Reinecke, M., Stahlbom, P. A., and Sandberg Nordquist, A. C. (1993). The biological role of truncated IGF-1 and the tripeptide OPE in the CNS. Ann NY Acad. Sci. 692, 183-191.
309. Sasaoka, T., Rose, D. W., Jhun, B. H., Saltiel, A. R., Draznin, B., and Olefsky, J. M. (1994). Evidence for a functional role of She proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor. J. Biol. Chem. 269, 13689-13694.
310. Scavo, L., Alemany, J., Roth, J., and De Pablo, F. (1989). Insulin-like growth factor I is stored in the yolk of the avian egg. Biochem. Biophys. Res. Commun. 162, 1167-1173.
311. Scavo, L., Shuldiner, A. R., Serrano, J., Dashner, R., Roth, J., and DePablo, F. (1991). Genes encoding receptors for insulin and insulin-like growth factor I are expressed in Xenopus oocytes and embryos. Proc. Natl. Acad. Sci. USA 88, 6214-6218.
312. Schalch, D. S., Heinrich, U. E., Draznin, B., Johnson, C. J., and Miller, L. L. (1979). Role of the liver in regulating somatomedin activity: Hormonal effects on the synthesis and release of insulin-like growth factor and its carrier protein by the isolated perfused rat liver. Endocrinology 104, 1143-1151.
313. Scharfmann, R., Corvol, M., and Czernichow, P. (1989). Characterization of insulin-like growth factor I produced by fetal rat pancreatic islet cells. Diabetes 38, 686-690.
314. Scheper, W., Holthuizen, P. E., and Sussenbach, J. S. (1996). Growth-condition-dependent regulation of insulin-like growth factor II mRNA stability. Biochem. J. 318, 195-201.
315. Schneider, A., and Hanke, W. (1996). Influence of insulin-like growth factors and insulin on the [35S]sulfate uptake by cartilage of the Axolotl (Ainbystonia mexicainim). Gen. Comp. Endocrinol. 104, 92-102.
316. Schober, D. A., Simmen, F. A., Hadsell, D. L., and Baumrucker, C. R. (1990). Perinatal expression of type I IGF receptors in porcine small intestine. Endocrinology 126, 1125-1132.
317. Schoen, T. J., Bondy, C. A., Zhou, J., Dhawan, R., Mazuruk, K., Arnold, D. R., Rodriguez, I. R., Waldbillig, R. J., Beebe, D. C., and Chader, G. J. (1995). Differential temporal and spatial expression of insulin-like growth factor binding protein-2 in developing chick ocular tissues. Invest. Ophthalmol. Visual Sci. 36, 2652-2662.
318. Schoen, T. J., Mazuruk, K., Potts, J., Waldbillig, R. J., Beebe, D., and Rodriguez, I. R. (1996). Cloning and characterization of a chick embryo cDNA and gene for insulin-like growth factor binding protein-2. Genbank Accession No. U150S6.
319. Schuller, A. G. P., Zwarthoff, E. C., and Drop, S. L. S. (1993). Gene expression of the six insulin-like growth factor binding proteins in the mouse conceptus during mid- and late-gestation. Endocrinology 132, 2544-2550.
320. Schuller, A. G. P., Groffen, C., van Neck, J. W., Zwarthoff, E. C., and Drop, S. L. S. (1994). cDNA cloning and mRNA expression of the six mouse insulin-like growth factor binding proteins. Mol. Cell. Endocrinol. 104, 57-66.
321. Schumacher, R., Soos, M. A., Schlessinger, J., Brandenburg, D., Siddle, K., and Ullrich, A. (1993). Signaling-competent receptor chimeras allow mapping of major insulin receptor binding domain determinants. J. Biol. Chem. 268, 1087-1094.
322. Schwander, J. C., Hauri, C., Zapf, J., and Froesch, E. R. (1983). Synthesis and secretion of insulin-like growth factor and its binding protein by the perfused rat liver: Dependence on growth hormone status. Endocrinology 113, 297-305.
323. Serrano, J., Shuldiner, A. R., Roberts, C. T., Le Roith, D., Jr., and De Pablo, F. (1990). The insulin-like growth factor I (IGF-I) gene is expressed in chick embryos. Endocrinology 127, 1547-1549.
324. Sevala, V. M., Sevala, V. L., and Loughton, B. G. (1993). Insulin-like molecules in the beetle Tenebrio molitor. Cell Tissue Res. 273, 71-77.
325. Shamblott, M. J., and Chen, T. T. (1992). Identification of a second insulin-like growth factor in a fish species. Proc. Nail. Acad. Sci. USA 89, 8913-8917.
326. Shamblott, M. J., and Chen, T. T. (1993). Age-related and tissue-specific levels of five forms of insulin-like growth factor mRNA in a teleost. Mol. Mar. Biol. Biotechnol. 2, 351-361.
327. Shamblott, M. J., Cheng, C. M., Bolt, D., and Chen, T. T. (1995). Appearance of insulin-like growth factor mRNA in the liver and pyloric caeca of a teleost in response to exogenous growth hormone. Proc. Natl. Acad. Sci. USA 92, 6943-6949.
328. Shapiro, B., and Pimstone, B. L. (1977). A phylogenetic study of sulphation factor activity in 26 species. J. Endocrinol. 74, 129-135.
329. Shen, S.-J., Daimon, M., Wang, C.-Y., Jansen M., and Ilan, J. (1988). Isolation of an insulin-like growth factor II cDNA with a unique 5-prime untranslated region from human placenta. Proc. Natl. Acad. Sci. USA 85, 1947-1951.
330. Shepherd, B. S., Sakamoto, T., Nishioka, R. S., Richman, N. H., III, Mori, I., Madsen, S. S., Chen, T. T., Hirano, T., Bern, H. A., and Grau, E. G. (1997). Somatotrophic actions of homologous growth hormone and prolactins in the euryhyaline teleost, the tilapia, Orcochromis inossambicus. Proc. Natl. Acad. Sci. USA 94, 2068-2072.
331. Shimasaki, S., and Ling, N. (1991). Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5, and -6). Growth Factor Res. 3, 243-266.
332. Shimasaki, S., Koba, A., Mercado, M., Shimonaka, M., and Ling, N. (1989). Complementary DNA structure of the high molecular weight rat insulin-like growth factor binding protein (IGF-BP3) and tissue distribution of its mRNA. Biochem. Biophys. Res. Commun. 165, 907-912.
333. Shimasaki, S., Shimonaka, M., Ui, M., Inouye, S., Shibata, F., and Ling, N. (1990a). Structural characterization of a follicle-stimulating hormone action inhibitor in porcine ovarian follicular fluid. J. Biol. Chem. 265, 2198-2202.
334. Shimasaki, S., Uchiyama, F., Shimonaka, M., and Ling, N. (1990b). Molecular cloning of the cDNAs encoding a novel insulin-like growth factor-binding protein from rat and human. Mol. Endocrinol. 4, 1451-1458.
335. Shimasaki, S., Gao, L., Shimonaka, M., and Ling, N. (1991a). Isolation and molecular cloning of insulin-like growth factor-binding protein-6. Mol. Endocrinol. 5, 938-948.
336. Shimasaki, S., Shimonaka, M., Zhang, H.-P., and Ling, N. (1991b). Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human. J. Biol. Chem. 266, 10646-10653.
337. Shimatsu, A., and Rotwein, P. (1987a). Mosaic evolution of the insulin-like growth factors. Organization, sequence, and expression of the rat insulin-like growth factor I gene. J. Biol. Chem. 262, 7894-7900.
338. Shimatsu, A., and Rotwein, P. (1987b). Sequence of two rat insulin-like growth factor I mRNAs differing within the 5′untranslated region. Nucleic Acids Res. 15, 7196.
339. Shuldiner, A. R., Nirula, A., Scott, L. A., and Roth, J. (1990). Evidence that Xenopus laevis contains two different nonallelic insulin-like growth factor I genes. Biochem. Biophys. Res. Commun. 166, 223-230.
340. Siegfried, J. M., Kasprzyk, P. G., Treston, A. M., Mulshine, J. L., Quinn, K. A., and Cuttitta, F. (1992). A mitogenic peptide amide encoded within the E peptide domain of the insulin-like growth factor 1B prohormone. Proc. Natl. Acad. Sci. USA 89, 8107-8111.
341. Sieradzki, J., Fleck, H., Chatterjee, A. K., and Schatz, H. (1988). Stimulatory effect of insulin-like growth factor-I on (3H) thymidine incorporation, DNA content and insulin biosynthesis and secretion of isolated pancreatic islets. J. Endocrinol. 117, 59-62.
342. Siharath, K., and Bern, H. A. (1993). The physiology of insulin-like growth factors (IGFs) and its bindings proteins in teleost fishes. Proc. Zool. Soc. Calcutta Haldanc Comm. Vol. 113-124.
343. Siharath, K., Nishioka, R. S., and Bern, H. A. (1995). In vitro production of IGF-binding proteins (IGF-BP) by various organs of the striped bass, Morone saxatalis. Aquaculture 135, 195-202.
344. Siharath, K., Kelley, K. M., and Bern, H. A. (1996). A low-molecular-weight (25 kDa) IGF-binding protein is increased with growth inhibition in the fasting striped bass Morone saxatalis. Gen. Comp. Endocrinol. 102, 307-316.
345. Sinclair, A. H., and Graves, J. A. M. (1991). Gene mapping in marsupials: Detection of an ancient gene cluster. Genomics 9, 581-586.
346. Skolnik, E. Y., Batzer, A., Li, N., Lee, C. H., Lowenstein, E., Mohammadi, M., Margolis, B., and Schlessinger, J. (1993). The function of GRB2 in linking the insulin receptor to Ras signaling pathways. Science 260, 1953-1955.
347. Skyrud, T., Andersen, Ø., Alestrom, P., and Gautvik, K. M. (1989). Effects of recombinant growth hormone and insulin-like growth factor 1 on body growth and blood metabolites in brook trout (Salvelinus fontinalis). Gen. Comp. Endocrinol. 75, 247-255.
348. Slootweg, M. C., Hoogerbrugge, C. M., de Poorter, T. L., Duursma, S. A., and van Buul Offers, S. C. (1990). The presence of classical IGF type 1 and type 2 receptors in mouse osteoblasts: Autocrine/paracrine growth of IGFs? J. Endocrinol. 125, 271-277.
349. Smit, A. B., Vreugdenhil, E., Ebberink, R., Geraerts, W. P. M., Klootwijk, J., and Joosse, J. (1988). Growth controlling molluscan neurones produce the precursor of an insulin-related peptide. Nature 331, 335-338.
350. Smit, A. B., Geraerts, W. P. M., Meester, I., van Heerikhuizen, H., and Joosse, J. (1991). Characterization of a cDNA clone encoding molluscan insulin-related poptide II of Lymnaea stagnate. Eur. J. Biochem. 199, 699-703.
351. Smit, A. B., Thijsen, S. F. T., Geraerts, W. P. M., Meester, I., van Heerikhuizen, H., and Joosse, J. (1992). Characterization of a cDNA clone encoding molluscan insulin-related peptide V of Lymnaea stagnalis. Mol. Brain Res. 14, 7-12.
352. Smit, A. B., van Marie, M., van Elk, R., van Heerikhuizen, H., and Geraerts, W. P. M. (1993). Evolutionary conservation of the insulin gene structure in invertebrates: cloning of the gene encoding molluscan insulin-related peptide III from Lymnaea stagnalis. J. Mol. Endocrinol. 11, 103-113.
353. Smit, A. B., Spijker, S., van Minnen, J., Burke, J. F., de Winter, F., van Elk, R., and Geraerts, W. P. M. (1996). Expression and characterization of molluscan insulin-related peptide VII from the mollusc Lymnaea stagnalis. Neuroscience 70, 589-596.
354. Soares, M. B., Turken, A., Ishii, D., Mills, L., Episkopou, V., Cotter, S., Zeitlin, S., and Efstratiadis, A. (1986). Rat insulin-like growth factor II gene. A single gene with two promoters expressing a multitranscript family. J. Mol. Biol. 192, 737-752.
355. Söder, O., Bang, P., Wahab, A., and Parvinen, M. (1992). Insulin-like growth factors selectively stimulate spermatogonial, but not meiotic, deoxyribonucleic acid synthesis during rat spermatogenesis. Endocrinology 131, 2344-2350.
356. Sonetti, D., van Heumen, W. R. A., and Roubos, E. W. (1992). Light- and electron-microscopic immunohistochemistry of a molluscan insulin-related peptide in the central nervous system of Planorbarins corneus. Cell Tissue Res. 267, 473-481.
357. Soos, M. A., Field, C. E., and Siddle, K. (1993). Purified hybrid insulin/insulin-like growth factor I receptors bind insulin-like growth factor I but not insulin, with high affinity. Biochem. J. 290, 419-426.
358. Spiteri-Grech, J., and Nieschlag, E. (1992). The role of growth hormone and insulin-like growth factor I in the regulation of male reproductive function. Harm. Res. 38(Suppl. 1), 22-27.
359. Steele-Perkins, G., Turner, J., Edman, J., Hari, J., Pierce, S. B., Stover, C., Rutter, W., and Roth, R. (1988). Expression and characterization of a functional human insulin-like growth factor I receptor. J. Biol. Chem. 263, 11486-11492.
360. Steiner, D. F., Chan, S. J., Docherty, K., Emdin, S. O., Dodson, G. G., and Falkmer, S. (1985). Evolution of polypeptide hormones and their precursor processing mechanisms. In "Evolution and Tumor Pathology of the Neuroendocrine System" (S. Falkmer, R. Hakanson, and F. Sundler, eds.), pp. 203-223. Elsevier, Amsterdam.
361. Stewart, C. E. H., and Rotwein, P. (1996). Growth, differentiation and survival. Multiple physiological functions for insulin-like growth factors. Physiol. Rev. 76, 1005-1026.
362. Stylianopoulou, F., Efstratiadis, A., Herbert, J., and Pintar, J. (1988). Patterns of the insulin-like growth factor II gene expression during rat embryogenesis. Development 103, 497-506.
363. Sussenbach, J. S., Steeburgh, P. H., Jansen, E., Meinsma, D., van Dijk, M. A., Holthuizen, P., de Moor, C. H., Jansen, M., and Van den Brande, J. L. (1991). Structure and post-transcriptional regulation of expression of the human IGF-I and -II genes. In "Modern Concepts of Insulin-like Growth Factors" (E. M. Spencer, ed.), pp. 639-654. Elsevier, Amsterdam/New York.
364. Svrzic, D., and Schubert, D. (1990). Insulin-like growth factor 1 supports embryonic nerve survival. Biochem. Biophys. Res. Commun. 172, 54-60.
365. Swisshelm, K., Ryan, K., Tsuchiya, K., and Sager, R. (1995). Enhanced expression of an insulin growth factor-like binding protein (mac25) in senescent human mammary epithelial cells and induced expression with retinoic acid. Proc. Natl. Acad. Sci. USA 92, 4472-4476.
366. Takenaka, A., Mori, M., Yamada, S., Ohgane J., Takahashi, S., and Noguchi, T. (1996). Nutritional regulation of gene expression of insulin-like growth factor-binding proteins and the acid-labile subunit in various tissues of rats. J. Endocrinol. 150, 33-41.
367. Tally, M., Enberg, G., Li, C. H., and Hall, K. (1987). Specifity of the human IGF-2 receptor. Biochem. Biophys. Res. Commun. 147, 1206-1212.
368. Tanaka, M., Hayashida, Y., Sakaguchi, K., Ohkubo, T., Wakita, M., Hoshino, S., and Nakashima, K. (1996). Growth hormone-independent expression of insulin-like growth factor I messenger ribonucleid acid in extrahepatic tissues of the chicken. Endocrinology 137, 30-34.
369. Thissen, J.-P., Ketelslegers, J.-M., and Underwood, L. E. (1994). Nutrional regulation of the insulin-like growth factors. Endocr. Rev. 15, 80-101.
370. Thorndyke, M. C., Purvis, D., and Plisetskaya, E. M. (1989). Insulin-like immunoreactivity in the brain of two hagfishes. Eptalretus stouti and Myxine glutinosa. Gen. Comp. Endocrinol. 76, 371-381.
371. Todd, S., Yoshida, M. C., Fang, X. E., McDonald, L., Jacobs, J., Heinrich, G., Bell, G. L., Naylor, S. L., and Sakaguchi, A. Y. (1985). Genes for insulin I and II, parathyroid hormone, and calcitonin are on rat chromosome I. Biochem. Biophys. Res. Commun. 131, 1175-1180.
372. Tonin, P., Ehrenborg, E., Lenoir, G., Feunteun, J., Lynch, H., Morgan, K., Zazzi, H., Vivier, A., Pollack, M., Huynh, H., Luthman, H., Larsson, G., and Narod, S. (1993). The human insulin-like growth factor binding protein 4 gene maps to chromosome region 17q12-21.1 and is close to the gene for hereditary breast-ovarian cancer. Genomics 18, 414-417.
373. Toretsky, J. A., and Helman, L. J. (1996). Involvement of IGF-II in human cancer. J. Endocrinol. 149, 367-372.
374. Ullrich, A., Berman, C. H., Dull, T. J., Gray, A., and Lee, J. M. (1984). Isolation of the human insulin-like growth factor I gene using a single synthetic DNA probe. EMBO J. 3, 361-364.
375. Ullrich, A., Gray, A., Tam, A. W., Yang-Feng, T., Tsubokawa M., Collins, C., Henzel, W., Le Bon, T., Kathuria, S., Chen, E., Jacobs, S., Francke, U., Ramahandran, J., and Fujita-Yamaguchi, Y. (1986). Insulin-like growth factor I receptor primary structure, comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J. 5, 2503-2512.
376. Underwood, L. E., Thissen, J.-P., Ketelslegers, J.-M., and Clemmons, D. R. (1994). Hormonal and nutritional regulation of IGF-I and its binding proteins. Harm. Res. 42, 145-151.
377. Upton, F. Z., Szabo, L., Wallace, J. G., and Ballard, F. J. (1990). Characterisation and cloning of a bovine insulin-like growth factor-binding protein. J. Mol. Endocrinol. 5, 77-84.
378. Upton, F. Z., Chan, S. J., Steiner, D. F., Wallace, J. G., and Ballard, F. J. (1993). Evolution of insulin-like growth factor binding proteins. Growth Regul. 3, 29-32.
379. Upton, F. Z., Francis, G. L., Chan, S. J., Steiner, D. F., Wallace, J. G., and Ballard, F. J. (1997). Evolution of the insulin-like growth factor (IGF) function-Production and characterization of recombinant hagfish IGF. Gen. Comp. Endocrinol. 105, 79-90.
380. Van Buul-Offers, S. C., De Haan, K., Reijnen-Gresnigt, M. G., Meinsma, D., Jansen, M., Oei, S. L., Bonte, E. J., Sussenbach, J. S., and Van Den Brande, J. L. (1995). Overexpression of human insulin-like growth factor-II in transgenic mice causes increased growth of the thymus. J. Endocrinol. 144, 491-502.
381. Vannelli, B. G., Barni, T., Orlando, C., Natali, A., Serio, M., and Balboni, G. C. (1988). Insulin-like growth factor I (IGF-I) and IGF-I receptor in humen testis: An immunohistochemical study. Fertil. Steril. 49, 666-669.
382. Van Schravendijk, C. F. H., Heylen, L., Van den Brande, J. L., and Pipeleers, D. G. (1987). Evidence for the presence of type I insulin-like growth factor receptors on rat pancreatic A and B cells. Endocrinology 121, 1784-1788.
383. Van Schravendijk, C. F. H., Foriers, A., Van den Brande, J. L., and Pipeleers, D. G. (1990). Direct effect of insulin and insulin-like growth factor on the secretory activity of rat pancreatic beta cells. Diabetologica 33, 649-653.
384. Vasilatos-Younken, R., Cravener, T. L., Cogburn, L. A., Mast, M. G., and Wellenreiter, R. H. (1988). Effect of pattern of administration on the response to exogenous pituitary-derived chicken growth hormone by broiler-strain pullets. Gen. Comp. Endocrinol. 71, 268-283.
385. Verhaert, P. D. E. M., Downer, R. G. H., Huybrechts, R., and De Loof, A. (1989). A substance resembling somatomedin C in the American cockroach. Regul. Pept. 25, 99-110.
386. Voutilainen, R., and Miller, W. L. (1988). Developmental and hormonal regulation of mRNAs for insulin-like growth factor II and steroidogenic enzymes in human fetal adrenals and gonads. DNA 1, 9-15.
387. Waldbillig, R. J., Arnold, D. R., Fletcher, T., and Chader, G. J. (1991). Insulin and IGF-I in developing chick neural retina and pigment epithelium: A characterization of binding and structural differences. Exp. Eye Res. 53, 13-22.
388. Wallis, A. E., and Devlin, R. H. (1993). Duplicate insulin-like growth factor I genes in salmon display alternative splicing pathways. Mol. Endocrinol. 7, 409-422.
389. Wang, E., Wang, J., Chin, E., Zhou, J., and Bondy, C. A. (1995). Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis. Endocrinology 136, 2741-2751.
390. Ward, A., Bates, P., Fisher, R., Richardson, L., and Graham, C. F. (1994). Disproportionate growth in mice with igf-2 transgenes. Proc. Natl. Acad. Sci. USA 91, 10365-10369.
391. Wathes, D. C., Perks, C. M., Davis, A. J., and Denning-Kendall, P. A. (1995). Regulation of insulin-like growth factor-I and progesterone synthesis by insulin and growth hormone in the ovine ovary. Biol. Reprod. 53, 882-889.
392. Wente, S. R., and Rosen, O. M. (1990). Insulin-receptor approaches to studying protein kinase domain. Diabetes Care 13, 280-287.
393. Werner, H., Woloschack, M., Adamo, M., Shen-Orr, Z., Roberts, C. T., Jr., and LeRoith, D. (1989). Developmental regulation of the rat insulin-like growth factor I receptor gene. Proc. Natl. Acad. Sci. USA 86, 7451-7455.
394. Werner, H., Hernandez-Sanchez, C., Karnieli, E., and LeRoith, D. (1995). The regulation of IGF-I receptor gene expression. Int. J. Biochem. Cell Biol. 27, 987-994.
395. Werther, G. A., Russo, V., Cheesma, H., and Edmondson, S. (1994). IGF-I as a paracrine growth factor in developing rat brain. In "The Insulin-like Growth Factors and Their Regulatory Proteins" (R. C. Baxter, P. D. Gluckman, and R. G. Rosenfeld, eds.), pp. 291-294. Elsevier, Amsterdam/New York.
396. Westlund, B., Dahms, N. M., and Korfield, S. (1991). The bovine mannose-6-phosphate/ insulin-like growth factor II receptor. Localization of mannose-6-phosphate binding sites to domains 1-3 and 7-11 of the extracytoplasmic region. J. Biol. Chem. 266, 23233-23239.
397. Wolf, E., Kramer, R., Blum, W. F., Foil, J., and Brem, G. (1994). Consequences of postnatally elevated insulin-like growth factor-II in transgenic mice: Endocrine changes and effects on body and irgan growth. Endocrinology 135, 1877-1896.
398. Woo, S. L. C., Lidsky, A., Law, M., and Kao, F. T. (1984). Regional mapping of the human phenylalanine hydroxylase gene and PKU locus to 12q21-qter. Am. J. Hum. Genet. 36, 210S.
399. Wood, T. L. (1995). Gene targeting and transgenic approaches to IGF and IGF binding protein function. Am. J. Physiol. E. 269, 613-622.
400. Yang, H., Adamo, M. L., Koval, A. P., McGuinness, M. C., Ben-Hur, H., Yang, Y., LeRoith, D., and Roberts, C. T. (1995). Alternative leader sequences in insulin-like growth factor I mRNAs modulate translational efficiency and encode multiple signal peptides. Mol. Endocrinol. 9, 1380-1395.
401. Yoshimura, Y., Iwashita, M., Karube, M., Oda, T., Akiba, M., Shiokawa, S., Ando, M., Yoshinaga, A., and Nakamura, Y. (1994). Growth hormone stimulates follicular development by stimulating ovarian production of insulin-like growth factor I. Endocrinology 135, 887-894.
402. Zackenfels, K., Oppenheim, R. W., and Rohrer, H. (1995). Evidence for an important role of IGF-I and IGF-II for the early development of chick sympathetic neurons. Neuron 14, 731-741.
403. Zapf, J. (1995). Physiological role of the insulin-like growth factor binding proteins. Eur. J. Endocrinol. 132, 645-654.
404. Zapf, J., Morrell, B., Walter, H., Laron, Z., and Froesch, E. R. (1980). Serum levels of insulin-like growth factor (IGF) and its carrier protein in various metabolic disorders. Acta Endocrinol. 95, 505-517.
405. Zenobi, P. D., Graf, S., Ursprung, H., and Froesch, E. R. (1992). Effects of insulin-like growth factor-I on glucose tolerance, insulin levels, and insulin secretion. J. Clin. Invest. 89, 1908-1913.
406. Zhang, Q., Tally, M., Larsson, O., Kennedy, R. T., Huang, L., Hall, K., and Berggren, P.-O. (1997). Insulin-like growth factor II signaling through the insulin-like growth factor II/ mannose-6-phosphate receptor promotes exocytosis in insulin-secreting cells. Proc. Natl. Acad. Sci. USA 94, 6232-6237.
407. Zhao, A. Z., Zhao, H., Teague, J., Fujimoto, W., and Beavo, J. A. (1997). Attenuation of insulin secretion by insulin-like growth factor 1 is mediated through activation of phosphodiesterase 3B. Proc. Natl. Acad. Sci. USA 94, 3223-3228.
408. Zhou, J., and Bondy, C. (1993). Anatomy of the insulin-like growth factor system in the human testis. Fertil. Steril. 60, 897-904.
409. Zumbrunn, J., and Trueb, B. (1996). Primary structure of a putitative serine protease specific for IGF-binding proteins. FEBS Lett. 398, 187-192.
410. Zumkeller, W., and Schofield, P. N. (1992). The role of insulin-like growth factors and IGF-binding-proteins in the physiological and pathological processes of the kidney. Virchows Arch. B 62, 207-220.
411. Zumstein, P. P., Lüthi, C., and Humbel, R. E. (1985). Amino acid sequence of a variant proform of insulin-like growth factor II. Proc. Natl. Acad. Sci. USA 82, 3169-3172.