Toll Like Receptor 3 Plays a Critical Role in the Progression and Severity of Acetaminophen-Induced Hepatotoxicity

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Cavassani, Karen A ^a   Moreira, Ana Paula ^a   Habiel, David ^a   Ito, Toshihiro ^a   Coelho, Ana Lucia ^a   Allen, Ron M ^a   Hu, Bin ^b   Raphelson, Janna ^a   Carson IV, William F ^a   Schaller, Matthew A ^a   Lukacs, Nicholas W ^a   Omary, M Bishr ^b   Hogaboam, Cory M ^a   Kunkel, Steven L ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND; GLYCOPROTEIN P 15095; PARACETAMOL; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; FEMALE; IMMUNOREACTIVITY; LIVER CELL; LIVER FAILURE; LIVER TOXICITY; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

ACETAMINOPHEN; ANIMALS; ANTIBODIES, NEUTRALIZING; CHEMOKINES; DISEASE PROGRESSION; DRUG-INDUCED LIVER INJURY; ENZYME ACTIVATION; FEMALE; HEPATOCYTES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIGANDS; LIVER; MICE; MICE, INBRED C57BL; NEUTRALIZATION TESTS; PHOSPHORYLATION; TOLL-LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 84878812959     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065899     Document Type: Article

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