-
1
-
-
0026488079
-
Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study
-
Magnusson I, Rothman DL, Katz LD, Shulman RG, Shulman GI, (1992) Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study. J Clin Invest 90: 1323-1327.
-
(1992)
J Clin Invest
, vol.90
, pp. 1323-1327
-
-
Magnusson, I.1
Rothman, D.L.2
Katz, L.D.3
Shulman, R.G.4
Shulman, G.I.5
-
2
-
-
0035181809
-
Quantitative contributions of gluconeogenesis to glucose production during fasting in type 2 diabetes mellitus
-
Wajngot A, Chandramouli V, Schumann WC, Ekberg K, Jones PK, et al. (2001) Quantitative contributions of gluconeogenesis to glucose production during fasting in type 2 diabetes mellitus. Metabolism 50: 47-52.
-
(2001)
Metabolism
, vol.50
, pp. 47-52
-
-
Wajngot, A.1
Chandramouli, V.2
Schumann, W.C.3
Ekberg, K.4
Jones, P.K.5
-
3
-
-
0141866862
-
Measurement of fractional whole-body gluconeogenesis in humans from blood samples using 2H nuclear magnetic resonance spectroscopy
-
Kunert O, Stingl H, Rosian E, Krssak M, Bernroider E, et al. (2003) Measurement of fractional whole-body gluconeogenesis in humans from blood samples using 2H nuclear magnetic resonance spectroscopy. Diabetes 52: 2475-2482.
-
(2003)
Diabetes
, vol.52
, pp. 2475-2482
-
-
Kunert, O.1
Stingl, H.2
Rosian, E.3
Krssak, M.4
Bernroider, E.5
-
4
-
-
78649449365
-
Glycogen storage disease type I and G6Pase-beta deficiency: etiology and therapy
-
Chou JY, Jun HS, Mansfield BC, (2010) Glycogen storage disease type I and G6Pase-beta deficiency: etiology and therapy. Nat Rev Endocrinol 6: 676-688.
-
(2010)
Nat Rev Endocrinol
, vol.6
, pp. 676-688
-
-
Chou, J.Y.1
Jun, H.S.2
Mansfield, B.C.3
-
5
-
-
84863526545
-
Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
-
Wang B, Hsu SH, Frankel W, Ghoshal K, Jacob ST, (2012) Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. Hepatology 56: 186-197.
-
(2012)
Hepatology
, vol.56
, pp. 186-197
-
-
Wang, B.1
Hsu, S.H.2
Frankel, W.3
Ghoshal, K.4
Jacob, S.T.5
-
6
-
-
80054776840
-
Promoter hypermethylation mediated downregulation of FBP1 in human hepatocellular carcinoma and colon cancer
-
Chen M, Zhang J, Li N, Qian Z, Zhu M, et al. (2011) Promoter hypermethylation mediated downregulation of FBP1 in human hepatocellular carcinoma and colon cancer. PLoS One 6: e25564.
-
(2011)
PLoS One
, vol.6
-
-
Chen, M.1
Zhang, J.2
Li, N.3
Qian, Z.4
Zhu, M.5
-
7
-
-
21144443890
-
Hepatocellular carcinoma in glycogen storage disease type Ia: a case series
-
Franco LM, Krishnamurthy V, Bali D, Weinstein DA, Arn P, et al. (2005) Hepatocellular carcinoma in glycogen storage disease type Ia: a case series. J Inherit Metab Dis 28: 153-162.
-
(2005)
J Inherit Metab Dis
, vol.28
, pp. 153-162
-
-
Franco, L.M.1
Krishnamurthy, V.2
Bali, D.3
Weinstein, D.A.4
Arn, P.5
-
8
-
-
0030987931
-
Hepatocellular adenomas in glycogen storage disease type I and III: a series of 43 patients and review of the literature
-
Labrune P, Trioche P, Duvaltier I, Chevalier P, Odievre M, (1997) Hepatocellular adenomas in glycogen storage disease type I and III: a series of 43 patients and review of the literature. J Pediatr Gastroenterol Nutr 24: 276-279.
-
(1997)
J Pediatr Gastroenterol Nutr
, vol.24
, pp. 276-279
-
-
Labrune, P.1
Trioche, P.2
Duvaltier, I.3
Chevalier, P.4
Odievre, M.5
-
9
-
-
0036387417
-
Glycogen storage disease type I: diagnosis, management, clinical course and outcome. Results of the European Study on Glycogen Storage Disease Type I (ESGSD I)
-
Rake JP, Visser G, Labrune P, Leonard JV, Ullrich K, et al. (2002) Glycogen storage disease type I: diagnosis, management, clinical course and outcome. Results of the European Study on Glycogen Storage Disease Type I (ESGSD I). Eur J Pediatr 161Suppl 1: S20-34.
-
(2002)
Eur J Pediatr
, vol.161
-
-
Rake, J.P.1
Visser, G.2
Labrune, P.3
Leonard, J.V.4
Ullrich, K.5
-
10
-
-
0028147648
-
Glycogen storage disease in adults
-
Talente GM, Coleman RA, Alter C, Baker L, Brown BI, et al. (1994) Glycogen storage disease in adults. Ann Intern Med 120: 218-226.
-
(1994)
Ann Intern Med
, vol.120
, pp. 218-226
-
-
Talente, G.M.1
Coleman, R.A.2
Alter, C.3
Baker, L.4
Brown, B.I.5
-
11
-
-
79951672283
-
Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas
-
Mutel E, Abdul-Wahed A, Ramamonjisoa N, Stefanutti A, Houberdon I, et al. (2011) Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas. J Hepatol 54: 529-537.
-
(2011)
J Hepatol
, vol.54
, pp. 529-537
-
-
Mutel, E.1
Abdul-Wahed, A.2
Ramamonjisoa, N.3
Stefanutti, A.4
Houberdon, I.5
-
12
-
-
0030691794
-
Early bioenergetic changes in hepatocarcinogenesis: preneoplastic phenotypes mimic responses to insulin and thyroid hormone
-
Bannasch P, Klimek F, Mayer D, (1997) Early bioenergetic changes in hepatocarcinogenesis: preneoplastic phenotypes mimic responses to insulin and thyroid hormone. J Bioenerg Biomembr 29: 303-313.
-
(1997)
J Bioenerg Biomembr
, vol.29
, pp. 303-313
-
-
Bannasch, P.1
Klimek, F.2
Mayer, D.3
-
13
-
-
79951962147
-
CREB and the CRTC co-activators: sensors for hormonal and metabolic signals
-
Altarejos JY, Montminy M, (2011) CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nat Rev Mol Cell Biol 12: 141-151.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 141-151
-
-
Altarejos, J.Y.1
Montminy, M.2
-
14
-
-
79959962745
-
Hormonal regulation of hepatic glucose production in health and disease
-
Lin HV, Accili D, (2011) Hormonal regulation of hepatic glucose production in health and disease. Cell Metab 14: 9-19.
-
(2011)
Cell Metab
, vol.14
, pp. 9-19
-
-
Lin, H.V.1
Accili, D.2
-
15
-
-
20644460348
-
Factors that control the tissue-specific transcription of the gene for phosphoenolpyruvate carboxykinase-C
-
Chakravarty K, Cassuto H, Reshef L, Hanson RW, (2005) Factors that control the tissue-specific transcription of the gene for phosphoenolpyruvate carboxykinase-C. Crit Rev Biochem Mol Biol 40: 129-154.
-
(2005)
Crit Rev Biochem Mol Biol
, vol.40
, pp. 129-154
-
-
Chakravarty, K.1
Cassuto, H.2
Reshef, L.3
Hanson, R.W.4
-
16
-
-
0034712818
-
What is a cAMP response unit?
-
Roesler WJ, (2000) What is a cAMP response unit? Mol Cell Endocrinol 162: 1-7.
-
(2000)
Mol Cell Endocrinol
, vol.162
, pp. 1-7
-
-
Roesler, W.J.1
-
17
-
-
28144439406
-
The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements
-
Vander Kooi BT, Onuma H, Oeser JK, Svitek CA, Allen SR, et al. (2005) The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements. Mol Endocrinol 19: 3001-3022.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 3001-3022
-
-
Vander Kooi, B.T.1
Onuma, H.2
Oeser, J.K.3
Svitek, C.A.4
Allen, S.R.5
-
18
-
-
0030613787
-
The role of HNF1alpha, HNF3gamma, and cyclic AMP in glucose-6-phosphatase gene activation
-
Lin B, Morris DW, Chou JY, (1997) The role of HNF1alpha, HNF3gamma, and cyclic AMP in glucose-6-phosphatase gene activation. Biochemistry 36: 14096-14106.
-
(1997)
Biochemistry
, vol.36
, pp. 14096-14106
-
-
Lin, B.1
Morris, D.W.2
Chou, J.Y.3
-
19
-
-
33846675889
-
Insulin represses phosphoenolpyruvate carboxykinase gene transcription by causing the rapid disruption of an active transcription complex: a potential epigenetic effect
-
Hall RK, Wang XL, George L, Koch SR, Granner DK, (2007) Insulin represses phosphoenolpyruvate carboxykinase gene transcription by causing the rapid disruption of an active transcription complex: a potential epigenetic effect. Mol Endocrinol 21: 550-563.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 550-563
-
-
Hall, R.K.1
Wang, X.L.2
George, L.3
Koch, S.R.4
Granner, D.K.5
-
20
-
-
84864027402
-
The histone demethylase Jhdm1a regulates hepatic gluconeogenesis
-
Pan D, Mao C, Zou T, Yao AY, Cooper MP, et al. (2012) The histone demethylase Jhdm1a regulates hepatic gluconeogenesis. PLoS Genet 8: e1002761.
-
(2012)
PLoS Genet
, vol.8
-
-
Pan, D.1
Mao, C.2
Zou, T.3
Yao, A.Y.4
Cooper, M.P.5
-
21
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, et al. (2004) Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119: 941-953.
-
(2004)
Cell
, vol.119
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
Mulligan, P.4
Whetstine, J.R.5
-
22
-
-
0035852637
-
CoREST is an integral component of the CoREST- human histone deacetylase complex
-
You A, Tong JK, Grozinger CM, Schreiber SL, (2001) CoREST is an integral component of the CoREST- human histone deacetylase complex. Proc Natl Acad Sci U S A 98: 1454-1458.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 1454-1458
-
-
You, A.1
Tong, J.K.2
Grozinger, C.M.3
Schreiber, S.L.4
-
23
-
-
0242669199
-
Coordinated histone modifications mediated by a CtBP co-repressor complex
-
Shi Y, Sawada J, Sui G, Affar el B, Whetstine JR, et al. (2003) Coordinated histone modifications mediated by a CtBP co-repressor complex. Nature 422: 735-738.
-
(2003)
Nature
, vol.422
, pp. 735-738
-
-
Shi, Y.1
Sawada, J.2
Sui, G.3
El Affar, B.4
Whetstine, J.R.5
-
24
-
-
68749108259
-
LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer
-
Wang Y, Zhang H, Chen Y, Sun Y, Yang F, et al. (2009) LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell 138: 660-672.
-
(2009)
Cell
, vol.138
, pp. 660-672
-
-
Wang, Y.1
Zhang, H.2
Chen, Y.3
Sun, Y.4
Yang, F.5
-
25
-
-
84862123313
-
The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells
-
Harris WJ, Huang X, Lynch JT, Spencer GJ, Hitchin JR, et al. (2012) The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells. Cancer Cell 21: 473-487.
-
(2012)
Cancer Cell
, vol.21
, pp. 473-487
-
-
Harris, W.J.1
Huang, X.2
Lynch, J.T.3
Spencer, G.J.4
Hitchin, J.R.5
-
26
-
-
84856962477
-
Enhancer decommissioning by LSD1 during embryonic stem cell differentiation
-
Whyte WA, Bilodeau S, Orlando DA, Hoke HA, Frampton GM, et al. (2012) Enhancer decommissioning by LSD1 during embryonic stem cell differentiation. Nature 482: 221-225.
-
(2012)
Nature
, vol.482
, pp. 221-225
-
-
Whyte, W.A.1
Bilodeau, S.2
Orlando, D.A.3
Hoke, H.A.4
Frampton, G.M.5
-
27
-
-
79957884078
-
LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells
-
Adamo A, Sese B, Boue S, Castano J, Paramonov I, et al. (2011) LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells. Nat Cell Biol 13: 652-659.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 652-659
-
-
Adamo, A.1
Sese, B.2
Boue, S.3
Castano, J.4
Paramonov, I.5
-
28
-
-
58149156264
-
The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation
-
Wang J, Hevi S, Kurash JK, Lei H, Gay F, et al. (2009) The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nat Genet 41: 125-129.
-
(2009)
Nat Genet
, vol.41
, pp. 125-129
-
-
Wang, J.1
Hevi, S.2
Kurash, J.K.3
Lei, H.4
Gay, F.5
-
29
-
-
34247348215
-
Opposing LSD1 complexes function in developmental gene activation and repression programmes
-
Wang J, Scully K, Zhu X, Cai L, Zhang J, et al. (2007) Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature 446: 882-887.
-
(2007)
Nature
, vol.446
, pp. 882-887
-
-
Wang, J.1
Scully, K.2
Zhu, X.3
Cai, L.4
Zhang, J.5
-
30
-
-
84862777766
-
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
-
Schenk T, Chen WC, Gollner S, Howell L, Jin L, et al. (2012) Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia. Nat Med 18: 605-611.
-
(2012)
Nat Med
, vol.18
, pp. 605-611
-
-
Schenk, T.1
Chen, W.C.2
Gollner, S.3
Howell, L.4
Jin, L.5
-
31
-
-
25144519737
-
An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation
-
Lee MG, Wynder C, Cooch N, Shiekhattar R, (2005) An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. Nature 437: 432-435.
-
(2005)
Nature
, vol.437
, pp. 432-435
-
-
Lee, M.G.1
Wynder, C.2
Cooch, N.3
Shiekhattar, R.4
-
32
-
-
33745187327
-
Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications
-
Lee MG, Wynder C, Schmidt DM, McCafferty DG, Shiekhattar R, (2006) Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications. Chem Biol 13: 563-567.
-
(2006)
Chem Biol
, vol.13
, pp. 563-567
-
-
Lee, M.G.1
Wynder, C.2
Schmidt, D.M.3
McCafferty, D.G.4
Shiekhattar, R.5
-
33
-
-
34147173308
-
trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1
-
Schmidt DM, McCafferty DG, (2007) trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1. Biochemistry 46: 4408-4416.
-
(2007)
Biochemistry
, vol.46
, pp. 4408-4416
-
-
Schmidt, D.M.1
McCafferty, D.G.2
-
34
-
-
33748463364
-
NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism
-
Pei L, Waki H, Vaitheesvaran B, Wilpitz DC, Kurland IJ, et al. (2006) NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism. Nat Med 12: 1048-1055.
-
(2006)
Nat Med
, vol.12
, pp. 1048-1055
-
-
Pei, L.1
Waki, H.2
Vaitheesvaran, B.3
Wilpitz, D.C.4
Kurland, I.J.5
-
35
-
-
57149089662
-
Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease
-
Chopra AR, Louet JF, Saha P, An J, Demayo F, et al. (2008) Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science 322: 1395-1399.
-
(2008)
Science
, vol.322
, pp. 1395-1399
-
-
Chopra, A.R.1
Louet, J.F.2
Saha, P.3
An, J.4
Demayo, F.5
-
36
-
-
0034667597
-
Characterization of the human liver fructose-1,6-bisphosphatase gene promoter
-
Herzog B, Waltner-Law M, Scott DK, Eschrich K, Granner DK, (2000) Characterization of the human liver fructose-1,6-bisphosphatase gene promoter. Biochem J 351 Pt 2: 385-392.
-
(2000)
Biochem J
, vol.351
, Issue.Pt 2
, pp. 385-392
-
-
Herzog, B.1
Waltner-Law, M.2
Scott, D.K.3
Eschrich, K.4
Granner, D.K.5
-
37
-
-
75149159101
-
Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis
-
Liu X, Wang X, Zhang J, Lam EK, Shin VY, et al. (2010) Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis. Oncogene 29: 442-450.
-
(2010)
Oncogene
, vol.29
, pp. 442-450
-
-
Liu, X.1
Wang, X.2
Zhang, J.3
Lam, E.K.4
Shin, V.Y.5
-
38
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, et al. (2007) High-resolution profiling of histone methylations in the human genome. Cell 129: 823-837.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
-
39
-
-
70349272130
-
KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints
-
Ciccone DN, Su H, Hevi S, Gay F, Lei H, et al. (2009) KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature 461: 415-418.
-
(2009)
Nature
, vol.461
, pp. 415-418
-
-
Ciccone, D.N.1
Su, H.2
Hevi, S.3
Gay, F.4
Lei, H.5
-
40
-
-
63049083734
-
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death
-
Saijo K, Winner B, Carson CT, Collier JG, Boyer L, et al. (2009) A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell 137: 47-59.
-
(2009)
Cell
, vol.137
, pp. 47-59
-
-
Saijo, K.1
Winner, B.2
Carson, C.T.3
Collier, J.G.4
Boyer, L.5
-
41
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
-
Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, et al. (2004) Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell 119: 121-135.
-
(2004)
Cell
, vol.119
, pp. 121-135
-
-
Lin, J.1
Wu, P.H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
-
42
-
-
70350331125
-
Establishment and characterization of a novel method for evaluating gluconeogenesis using hepatic cell lines, H4IIE and HepG2
-
Okamoto T, Kanemoto N, Ban T, Sudo T, Nagano K, et al. (2009) Establishment and characterization of a novel method for evaluating gluconeogenesis using hepatic cell lines, H4IIE and HepG2. Arch Biochem Biophys 491: 46-52.
-
(2009)
Arch Biochem Biophys
, vol.491
, pp. 46-52
-
-
Okamoto, T.1
Kanemoto, N.2
Ban, T.3
Sudo, T.4
Nagano, K.5
|