Delphinidin prevents hypoxia-induced mouse embryonic stem cell apoptosis through reduction of intracellular reactive oxygen species-mediated activation of JNK and NF-κB, and Akt inhibition

Apoptosis

Volumn 18, Issue 7, 2013, Pages 811-824

  Seo, Bit Na ^a   Ryu, Jung Min ^a   Yun, Seung Pil ^a   Jeon, Ji Hoon ^a   Park, Su Shin ^a   Oh, Keon Bong ^b   Park, Jin Ki ^b   Han, Ho Jae ^a  

^a Seoul National University   (South Korea)

^b National Institute of Animal Science   (South Korea)

Author keywords

Apoptosis; Delphinidin; Embryonic stem cells; Hypoxia

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; DELPHINIDIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; PROCASPASE 3; PROCASPASE 9; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL HYPOXIA; CELL PROTECTION; CYTOSOL; DOSE RESPONSE; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ACETYLCYSTEINE; ANIMALS; ANTHOCYANINS; ANTHRACENES; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL HYPOXIA; CELL LINE; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; MAP KINASE KINASE 4; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; NF-KAPPA B; OXYGEN; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84878709370     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-013-0838-2     Document Type: Article

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