Postconditioning attenuates cardiomyocyte apoptosis via inhibition of JNK and p38 mitogen-activated protein kinase signaling pathways

Apoptosis

Volumn 11, Issue 9, 2006, Pages 1583-1593

  Sun, He Ying ^a   Wang, Ning Ping ^a   Halkos, Michael ^a   Kerendi, Faraz ^a   Kin, Hajime ^a   Guyton, Robert A ^a   Vinten Johansen, Jakob ^a   Zhao, Zhi Qing ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiomyocytes; Hypoxia reoxygenation; JNK; p38; Postconditioning; TNF

Indexed keywords

ANISOMYCIN; CASPASE 3; CASPASE 8; LUCIGENIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; OXYGEN; PROTEIN BAX; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL HYPOXIA; CHEMOLUMINESCENCE; CONTROLLED STUDY; ENZYME MECHANISM; HEART MUSCLE CELL; ISCHEMIC PRECONDITIONING; NEWBORN; NONHUMAN; OXYGEN SUPPLY; POSTCONDITIONING; PRIORITY JOURNAL; RAT; REOXYGENATION; SIGNAL TRANSDUCTION;

ANIMALS; ANOXIA; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; DNA FRAGMENTATION; ISCHEMIC PRECONDITIONING, MYOCARDIAL; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33747437290     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-006-9037-8     Document Type: Article

References (42)

1. Zhao Z-Q, Corvera JS, Halkos ME et al (2003) Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol (Heart Circ Physiol) 285:579-588
2. Kin H, Zhao Z-Q, Sun H-Y et al (2004) Postconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting events in the early minutes of reperfusion. Cardiovasc Res 62:74-85
3. 2+ overload. Am J Phy 288:H1900-H1908
4. Yang X-M, Proctor JB, Cui L, Krieg T, Downey JM, Cohen MV (2004) Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways. J Am Coll Card 44:1103-1110
5. Darling CE, Jiang R, Maynard M, Whittaker P, Vinten-Johansen J, Przyklenk K (2005) Postconditioning via stuttering reperfusion limits myocardial infarct size in rabbit hearts: role of ERK1/2. Am J Physiol (Heart Circ Physiol) 289:H1618-H1626
6. Tsang A, Hausenloy DJ, Mocanu MM, Yellon DM (2004) Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway. Circul Res 95:230-232
7. Laskey WK (2005) Brief repetitive balloon occlusions enhance reperfusion during percutaneous coronary intervention for acute myocardial infarction: a pilot study. Catheteriz Cardiovasc Interven 65:361-367
8. Staat P, Rioufol G, Piot C et al (2005) Postconditioning the human heart. Circulation 112:2143-2148
9. Mackay K, Mochly-Rosen D (1999) An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia. J Biol Chem 274:6272-6279
10. Meldrum DR, Dinarello CA, Cleveland JC, Jr et al (1998) Hydrogen peroxide induces tumor necrosis factor alpha-mediated cardiac injury by a P38 mitogen-activated protein kinase-dependent mechanmism. Surgery 124:291-297
11. Klein JB, Wang GW, Zhou Z, Buridi A, Kang YJ (2002) Inhibition of tumor necrosis factor-alpha-dependent cardiomyocyte apoptosis by metallothionein. Cardiovasc Toxicol 2:209-218
12. Lee MW, Park SC, Yang YG , et al (2002) The involvement of reactive oxygen species (ROS) and p38 mitogen-activated protein (MAP(kinase in TRAIL/Apo2L-induced apoptosis. FEBS Letters 512:313-318
13. Osone S, Hosoi H, Kuwahara Y, Matsumoto Y, Iehara T, Sugimoto T (2004) Fenretinide induces sustained-activation of JNK/p38 MAPK and apoptosis in a reactive oxygen species-dependent manner in neuroblastoma cells. Int J Cancer 112:219-224
14. Yoshizumi M, Tsuchiya K, Tamaki T (2001) Signal transduction of reactive oxygen species and mitogen-activated protein kinases in cardiovascular disease. J Invest Med 48:11-24
15. Marczin N, Bundy RE, Hoare GS, Yacoub M (2003) Redox regulation following cardiac ischemia and reperfusion. Coron Artery Dis 14:123-133
16. Hahn RA, MacDonald BR, Morgan E et al (1992) Evaluation of LY203647 on cardiovascular leukotriene D4 receptors and myocardial reperfusion injury. Journal of Pharmacol Experim Therap 260:979-989
17. Gao F, Yue T-L, Shi D-W, et al (2002) p38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation. Cardiovasc Res 53:414-422
18. Clanachan AS, Jaswal JS, Gandhi M et al (2003) Effects of inhibition of myocardial extracellular-responsive kinase and p38 mitogen-activated protein kinase on mechanical function of rat hearts after prolonged hypothermic ischemia. Transplant 75:173-180
19. Cicconi S, Ventura N, Pastore D et al (2003) Characterization of apoptosis signal transduction pathways in HL-5 cardiomyocytes exposed to ischemia/reperfusion oxidative stress model. J Cell Physiol 195:27-37
20. Fan H, Sun B, Gu Q, Lafond-Walker A, Cao S, Becker LC (2002) Oxygen radicals trigger activation of NF-κB and AP-1 and upregulation of ICAM-1 in reperfused canine heart. Am J Physiol (Heart Circ Physiol) 282:H1778-H1786
21. Wang T, Zhang X, Li J-J (2002) The role of NF-κB in the regulation of cell stress responses. Intern Immunopharm 2:1509-1520
22. Meldrum DR (1998) Tumor necrosis factor in the heart. Am J Physiol 274:R577-R595
23. Zhao Z-Q, Vinten-Johansen J (2002) Myocardial apoptosis and ischemic preconditioning. Cardiovasc Res 55:438-455
24. + exchanger in hypoxia/re-oxygenation-induced neonatal rat cardiomyocyte apoptosis. Euro J Pharmacol 486:121-131
25. Laderoute KR, Webster KA (1997) Hypoxia/reoxygenation stimulates jun kinase activity through redox signaling in cardiac myocytes. Circul Res 80:336-344
26. Yang X-M, Philipp S, Downey JM, Cohen MV (2005) Postconditioning's protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3-kinase and guanylyl cyclase activation. Basic Res Cardiol 100:57-63
27. Kin H, Zatta AJ, Lofye MT et al (2005) Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine. Cardiovasc Res 67:124-133
28. Nakano A, Cohen MV, Critz SD, Downey JM (2000) SB 203580, an inhibitor of p38 MAPK, abolishes infarct-limiting effect of iscehmic preconditioning in isolated rabbit hearts. Basic Res Cardiol 95:466-471
29. Weinbrenner C, Liu GS, Cohen MV, Downey JM (1997) Phosphorylation of Tyrosine 182 of p38 mitogen activated protein kinase correlates with the protection of preconditioning in the rabbit heart. J Molec Cell Cardiol 29:2383-2391
30. Kaiser RA, Bueno OF, Lips DJ et al (2004) Targeted inhibition of p38 mitogen-activated protein kinase antagonizes cardiac injury and cell death following ischemia-reperfusion in vivo. J Biolog Chem 279:15524-15530
31. Ferrandi C, Ballerio R, Gaillard P et al (2004) Inhibition of c-Jun N-terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats. British J Pharmacol 142:953-960
32. Ballard-Croft C, White DJ, Maass DL, Hybki DP, Horton JW (2001) Role of p38 mitogen-activated protein kinase in cardiac myocyte seretion of the inflammatory cytokine TNF-alpha. Am J Physiol (Heart Circ Physiol) 280:H1970-H1981
33. Brown M, McGuinness M, Wright T et al (2005) Cardiac-specific blockade of NF-kappaB in cardiac pathophysiology: differences between acute and chronic stimuli in vivo. Am J Physiol (Heart Circ Physiol) 289:H466-H476
34. Haunstetter A, Izumo S (1998) Apoptosis. Basic mechanisms and implications for cardiovascular disease. Circulation Research 82:1111-1129
35. Ma X-L, Kumar S, Gao F , et al (1999) Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion. Circulation 99:1685-1691
36. Maekawa N, Wada H, Kanda T et al (2002) Improved myocardial ischemia/reperfusion injury in mice lacking tumor necrosis factor-alpha. J Am Coll Cardiol 39:1229-1235
37. Chandra J, Samali A, Orrenius S (2000) Triggering and modulation of apoptosis by oxidative stress. Free Radic Biol Medi 29:323-333
38. Esposti MD, Dive C (2003) Mitochondrial membrane permeabilisation by Bax/Bak. Biochem & Biophys Res Comm 304:455-461
39. Kuwana T, Newmeyer DD (2003) Bcl-2-family proteins and the role of mitochondria in apoptosis. Curr Opin Cell Biol 15:691-699
40. Halestrap AP, Kerr PM, Javadov S, Woodfield KY (1998) Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. Biochim Biophys Acta 1366:79-94
41. Kim JS, He L, Lemasters JJ (2003) Mitochondrial permeability transition: a common pathway to necrosis and apoptosis. Biochem & Biophys Res Comm 304:463-470
42. Sun K, Liu ZS, Sun Q (2004) Role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion injury and protective effect of ischemic postconditioning. World J Gastroenterol 10:1934-1938