PKC-δ inhibitors sustain self-renewal of mouse embryonic stem cells under hypoxia in vitro

Experimental and Molecular Medicine

Volumn 42, Issue 4, 2010, Pages 294-301

  Lee, Hyo Jong ^a   Jeong, Chul Ho ^b   Cha, Jong Ho ^a   Kim, Kyu Won ^a,c  

^a Seoul National University   (South Korea)

^b UNIVERSITY OF MINNESOTA   (United States)

^c Seoul National University   (South Korea)

Author keywords

Anoxia; Embryonic stem cells; Hypoxia inducible factor 1, Subunit; Protein kinase C ; Rottlerin

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LEUKEMIA INHIBITORY FACTOR RECEPTOR; PROTEIN KINASE C DELTA; PROTEIN KINASE C INHIBITOR; ROTTLERIN; STAT3 PROTEIN; LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA; LIFR PROTEIN, MOUSE; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL HYPOXIA; CELL RENEWAL; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; METABOLISM;

ANIMALS; CELL DIFFERENTIATION; CELL HYPOXIA; CELL LINE; CELL PROLIFERATION; DOWN-REGULATION; EMBRYONIC STEM CELLS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT; MICE; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; STAT3 TRANSCRIPTION FACTOR;

EID: 77951973499     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2010.42.4.028     Document Type: Article

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