Alzheimer's disease-associated polymorphisms in human OGG1 alter catalytic activity and sensitize cells to DNA damage

Free Radical Biology and Medicine

Volumn 63, Issue , 2013, Pages 115-125

  Jacob, Kimberly D ^a   Hooten, Nicole Noren ^a   Tadokoro, Takashi ^a   Lohani, Althaf ^a   Barnes, Janice ^a   Evans, Michele K ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

8 Oxoguanine; 8 Oxoguanine DNA glycosylase; Alzheimer's disease; Base excision repair; DNA damage; DNA repair; Free radicals; Oxidative stress

Indexed keywords

8 HYDROXYGUANINE; 8 OXOGUANINE DNA GLYCOSYLASE; DNA BASE; DNA GLYCOSYLTRANSFERASE; FREE RADICAL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; UNCLASSIFIED DRUG; XRCC1 PROTEIN;

ALZHEIMER DISEASE; ARTICLE; BRAIN TISSUE; CATALYSIS; CELL SURVIVAL; CELLULAR DISTRIBUTION; COLONY FORMATION; CONTROLLED STUDY; DISSOCIATION CONSTANT; DNA DAMAGE; DNA POLYMORPHISM; DNA PROTEIN COMPLEX; DNA REPAIR; EXCISION REPAIR; HELA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LOCALIZATION; THERMOSTABILITY;

EID: 84878691763     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.05.010     Document Type: Article

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