Factors that limit positron emission tomography imaging of P-glycoprotein density at the blood-brain barrier

Molecular Pharmaceutics

Volumn 10, Issue 6, 2013, Pages 2222-2229

  Kannan, Pavitra ^a,b   Pike, Victor W ^a   Halldin, Christer ^b   Langer, Oliver ^c,d   Gottesman, Michael M ^e   Innis, Robert B ^a   Hall, Matthew D ^e  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c AIT AUSTRIAN INSTITUTE OF TECHNOLOGY   (Austria)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

ABC transporters; blood brain barrier; density; imaging; inhibitors; positron emission tomography (PET)

Indexed keywords

LIGAND; MULTIDRUG RESISTANCE PROTEIN;

ANIMAL TISSUE; BLOOD BRAIN BARRIER; BRAIN; BRAIN CAPILLARY; CALCULATION; DENSITY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAT; REVIEW;

ATP-BINDING CASSETTE TRANSPORTERS; BLOOD-BRAIN BARRIER; BRAIN; HUMANS; P-GLYCOPROTEIN; POSITRON-EMISSION TOMOGRAPHY;

EID: 84878653022     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400011g     Document Type: Review

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