Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components

Proteomics

Volumn 13, Issue 10-11, 2013, Pages 1672-1686

  Ji, Hong ^a   Greening, David W ^a   Barnes, Thomas W ^b   Lim, Justin W ^b,d   Tauro, Bow J ^a,b   Rai, Alin ^a   Xu, Rong ^a   Adda, Christopher ^a   Mathivanan, Suresh ^a   Zhao, Wei ^c   Xue, Yanhong ^c   Xu, Tao ^c   Zhu, Hong Jian ^b   Simpson, Richard J ^a  

^a LA TROBE UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c INSTITUTE OF BIOPHYSICS   (China)

^d AB SCIEX (Distribution)   (Singapore)

Author keywords

Cancer; Cell biology; Exosomes; Metastasis; Protein complex; Secretome

Indexed keywords

ALIX PROTEIN; CALGRANULIN A; CALGRANULIN B; CAV1 PROTEIN; CD63 ANTIGEN; CLDN7 PROTEIN; EPHRIN B2; EPITHELIAL CELL ADHESION MOLECULE; FLOTILLIN 1; FLOTILLIN 2; JAGGED1; PROM1 PROTEIN; PROTEIN TYROSINE KINASE; RAP2A PROTEIN; SCATTER FACTOR RECEPTOR; TENASCIN; TNIK PROTEIN; TUMOR MARKER; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; ELECTRON MICROSCOPY; EXOSOME; HUMAN; HUMAN CELL; LIPID RAFT; METASTATIC COLORECTAL CANCER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEOMICS; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM-BINDING PROTEINS; CALGRANULIN A; CALGRANULIN B; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; ENDOTHELIAL CELLS; EPHRIN-B2; EXOSOMES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; MICE; NEOPLASM METASTASIS; PROTEIN-SERINE-THREONINE KINASES; PROTEOME; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TENASCIN;

EID: 84878630476     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201200562     Document Type: Article

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