Increased expression of tissue inhibitor of metalloproteinases type I (TIMP-I) in a more tumourigenic colon cancer cell line

Journal of Pathology

Volumn 192, Issue 4, 2000, Pages 455-459

  Hewitt, Robert E ^a,c   Brown, Kevin E ^b   Corcoran, Marta ^a   Stetler Stevenson, William G ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

Cell line; Colon; Differential display; Metastasis

Indexed keywords

GENE PRODUCT; MESSENGER RNA; PROTEIN CC3; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UNCLASSIFIED DRUG;

ARTICLE; CANCER INVASION; COLON CARCINOGENESIS; COLON CARCINOMA; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

BLOTTING, NORTHERN; BLOTTING, WESTERN; COLONIC NEOPLASMS; DISEASE PROGRESSION; GENE EXPRESSION; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; PROTEASE INHIBITORS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TISSUE INHIBITOR OF METALLOPROTEINASE-3; TUMOR CELLS, CULTURED;

EID: 0033675417     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH777>3.0.CO;2-E     Document Type: Article

References (32)

1. Validation of a model of colon cancer progression
2. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
3. Immunodetection of the presence or absence of full-length APC gene product in human colonic tissues
4. Lessons from hereditary colorectal cancer
5. Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer
6. Mutations in the p53 gene occur in diverse human tumour types
7. Correlations between S and G2 arrest and the cytotoxicity of camptothecin in human colon carcinoma cells
8. Detection of ras oncogenes by analysis of p21 proteins in human tumor cell lines
9. Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea
10. Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine
11. Loss of heterozygosity and base substitution at the APRT locus in mismatch-repair-proficient and -deficient colorectal carcinoma cell lines
12. Classification of human colorectal adenocarcinoma cell lines
13. Molecular cloning of five messenger RNAs differentially expressed in preneoplastic or neoplastic JB6 mouse epidermal cells: One is homologous to human tissue inhibitor of metalloproteinases-3
14. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
15. Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in rumor cell lines and human tumor tissues
16. Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family
17. A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma
18. The tissue inhibitor of metalloproteinases-3 gene in breast carcinoma: Identification of multiple polyadenylation sites and a stromal pattern of expression
19. Down-regulation of vascular endothelial growth factor in human colon carcinoma cell lines by antisense transfection decreases endothelial cell proliferation
20. Metastasis of human colon tumor cells in vivo: Correlation with the overexpression of plasminogen activators and 72 kDa gelatinase
21. In vivo and in vitro invasion in relation to phenotypic characteristics of human colorectal carcinoma cells
22. Modulation of matrilysin levels in colon carcinoma cell lines affects tumorigenicity in vivo
23. Transforming growth factor alpha and beta expression in human colon cancer lines: Implications for an autocrine model
24. Modulation of EGF receptor expression by differentiating agents in human colon carcinoma cell lines
25. Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium
26. Role of integrins and evidence for two distinct mechanisms mediating human colorectal carcinoma cell interaction with peritoneal mesothelial cells and extracellular matrix
27. Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion
28. Distribution of collagenase and tissue inhibitor of metalloproteinases (TIMP) in colorectal tumours
29. Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis
30. High levels of tissue inhibitor of metalloproteinases (TIMP-1) in colorectal cancer, as determined by enzyme linked immunosorbent assay (ELISA) correlate with poor outcome
31. Growth-promoting activity of tissue inhibitor of metalloproteinases-1 (TIMP-1) for a wide range of cells. A possible new growth factor in serum
32. In vitro suppression of programmed cell death of B cells by tissue inhibitor of metalloproteinases-1