Dieckol, a SARS-CoV 3CLpro inhibitor, isolated from the edible brown algae Ecklonia cava

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 13, 2013, Pages 3730-3737

  Park, Ji Young ^a,b   Kim, Jang Hoon ^a   Kwon, Jung Min ^a   Kwon, Hyung Jun ^a   Jeong, Hyung Jae ^a   Kim, Young Min ^a   Kim, Doman ^b   Lee, Woo Song ^a   Ryu, Young Bae ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chonnam National University   (South Korea)

Author keywords

Dieckol; Ecklonia cava; Eckol; Phlorotannin; SARS CoV

Indexed keywords

2 PHLOROECKOL; 7 PHLOROECKOL; ANTIVIRUS AGENT; DIECKOL; DIOXINODEHYDROECKOL; ECKOL; FUCODIPHLOROETHOL G; PHLOROFUCOFUROECKOL; PHLOROGLUCINOL; TANNIN DERIVATIVE; TRIPHLORETOL; UNCLASSIFIED DRUG; BENZOFURAN DERIVATIVE; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR;

ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ECKLONIA CAVA; HYDROGEN BOND; NONHUMAN; STRUCTURE ACTIVITY RELATION; SURFACE PLASMON RESONANCE; BROWN ALGA; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR DOCKING; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME;

ECKLONIA CAVA; PHAEOPHYCEAE; SARS CORONAVIRUS;

ANTIVIRAL AGENTS; BENZOFURANS; CYSTEINE PROTEASES; CYSTEINE PROTEINASE INHIBITORS; HUMANS; MOLECULAR DOCKING SIMULATION; PHAEOPHYTA; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME;

EID: 84878584191     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.04.026     Document Type: Article

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