SMRT compounds abrogate cellular phenotypes of ataxia telangiectasia in neural derivatives of patient-specific hiPSCs

Nature Communications

Volumn 4, Issue , 2013, Pages

  Lee, Peiyee ^a   Martin, Nathan T ^b   Nakamura, Kotoka ^b   Azghadi, Soheila ^a   Amiri, Mandana ^b   Ben David, Uri ^c   Perlman, Susan ^b   Gatti, Richard A ^a,b   Hu, Hailiang ^b   Lowry, William E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CELL DNA; NEW DRUG; SMALL MOLECULE READ THROUGH COMPOUND; UNCLASSIFIED DRUG;

CELL ORGANELLE; DISEASE PREVALENCE; GENETIC ANALYSIS; IDENTIFICATION METHOD; MUTATION; NEUROLOGY; NUMERICAL MODEL; PATHOLOGY; PHENOTYPE;

ARTICLE; ATAXIA TELANGIECTASIA; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FIBROBLAST; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL; NERVE CELL DIFFERENTIATION; NONSENSE MUTATION; PHENOTYPE; PLURIPOTENT STEM CELL;

ATAXIA TELANGIECTASIA; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CELL LINE; DNA DAMAGE; DNA REPAIR; FIBROBLASTS; HISTONES; HUMANS; INDUCED PLURIPOTENT STEM CELLS; NEURAL STEM CELLS; NEURONS; NUCLEAR REPROGRAMMING; PHENOTYPE; PHOSPHORYLATION; RADIATION, IONIZING; SMALL MOLECULE LIBRARIES;

ATAXIA TELANGIECTASIA; MURINAE;

EID: 84878545143     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2824     Document Type: Article

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