Mutational inactivation of herpes simplex virus 1 MicroRNAs identifies viral mRNA targets and reveals phenotypic effects in culture

Journal of Virology

Volumn 87, Issue 12, 2013, Pages 6589-6603

  Flores, Omar ^a   Nakayama, Sanae ^b   Whisnant, Adam W ^a   Javanbakht, Hassan ^c   Cullen, Bryan R ^a   Bloom, David C ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MICRORNA; MICRORNA H1 3P; MICRORNA H1 5P; MICRORNA H11 3P; MICRORNA H13 5P; MICRORNA H2 3P; MICRORNA H2 5P; MICRORNA H3 3P; MICRORNA H3 5P; MICRORNA H4 3P; MICRORNA H4 5P; MICRORNA H5 3P; MICRORNA H5 5P; MICRORNA H6 3P; MICRORNA H6 5P; MICRORNA H7 3P; MICRORNA H7 5P; MICRORNA H8 3P; MICRORNA H8 5P; RNA INDUCED SILENCING COMPLEX; UNCLASSIFIED DRUG; VIRUS RNA;

ANIMAL CELL; ARTICLE; BIOASSAY; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENE INACTIVATION; GENE INTERACTION; GENE LOSS; GENE MAPPING; GENE MUTATION; GENE TARGETING; HERPES SIMPLEX VIRUS 1; ICP0 GENE; ICP34.5 GENE; NERVE CELL; NONHUMAN; NUCLEOTIDE BINDING SITE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ANALYSIS; VIRUS CULTURE; VIRUS GENE; VIRUS REPLICATION;

ANIMALS; BINDING SITES; CELL LINE; FIBROBLASTS; GENE EXPRESSION REGULATION, VIRAL; HEK293 CELLS; HERPESVIRUS 1, HUMAN; HUMANS; IMMEDIATE-EARLY PROTEINS; MICE; MICRORNAS; MUTATION; NEURONS; NIH 3T3 CELLS; PHENOTYPE; RABBITS; RNA, MESSENGER; RNA, VIRAL; RNA-INDUCED SILENCING COMPLEX; UBIQUITIN-PROTEIN LIGASES; VIRAL PROTEINS; VIRUS REPLICATION;

HUMAN HERPESVIRUS 1;

EID: 84878537894     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00504-13     Document Type: Article

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