Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 11, 2000, Pages 6097-6101

  Leib, David A ^a   Machalek, Michael A ^a   Williams, Bryan R G ^b   Silverman, Robert H ^b   Virgin, Herbert W ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DOUBLE STRANDED RNA; PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE TARGETING; HERPES SIMPLEX VIRUS 1; HOST RESISTANCE; KNOCKOUT GENE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; VIRUS ATTENUATION; VIRUS CELL INTERACTION; VIRUS GENE; VIRUS MUTANT; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS VIRULENCE;

ANIMALS; EIF-2 KINASE; GENE TARGETING; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; IMMUNITY, NATURAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; VIRAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

EID: 0034705049     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.100415697     Document Type: Article

References (29)

1. Stark, G., Kerr, L., Williams, B. R. G., Silverman, R. H. & Schreiber, R. (1998) Annu. Rev. Biochem. 67, 27-64.
2. Vilcek, J. & Sen, G. C. (1996) in Virology, ed. Fields, B. N. (Lippencott-Raven, Philadelphia), pp. 375-399.
3. Muller, U., Steinhoff, U., Reis, L. F., Hemmi, S., Pavlovic, J., Zinkernagel, R. M. & Aguet, M. (1994) Science 264, 1918-1921.
4. Chou, J., Chen, J. J., Gross, M. & Roizman, B. (1995) Proc. Natl. Acad. Sci. USA 92, 10516-10520.
5. He, B., Gross, M. & Roizman, B. (1997) Proc. Natl. Acad. Sci. USA 94, 843-848.
6. Chou, J. & Roizman, B. (1994) Proc. Natl. Acad. Sci. USA 91, 5247-5251.
7. Chou, J., Kern, E. R., Whitley, R. J. & Roizman, B. (1990) Science 250, 1262-1266.
8. Bolovan, C. A., Sawtell, N. M. & Thompson, R. L. (1994) J. Virol. 68, 48-55.
9. Roberts, W. K., Hovanessian, A., Brown, R. E., Clemens, M. J. & Kerr, I. M. (1976) Nature (London) 264, 477-480.
10. Gale, M. & Katze, M. G. (1998) Pharmacol. Ther. 78, 29-46.
11. Kumar, A., Yang, Y.-L., Flati, V., Der, S., Kadereit, S., Haque, J., Deb, A., Reis, L., Weismann, C. & Williams, B. R. G. (1997) EMBO J. 16, 406-416.
12. He, B., Gross, M. & Roizman, B. (1998) J. Biol. Chem. 273, 20737-20743.
13. Leib, D. A., Harrison, T. E., Laslo, K. M., Machalek, M. A., Moorman, M. J. & Virgin, H. W. (1999) J. Exp. Med. 189, 663-672.
14. Rader, K. A., Ackland-Berglund, C., Miller, J., Repose, J. & Leib, D. A. (1993) J. Gen. Virol. 74, 1859-1869.
15. Strelow, L. I. & Leib, D. A. (1995) J. Virol. 69, 6779-6786.
16. Kaplitt, M. G., Tjuvajev, J. G., Leib, D. A., Berk, J., Pettigrew, K. D., Posner, J. B., Pfaff, D. W., Rabkin, S. D. & Blasberg, R. G. (1994) J. Neuro-Oncol. 19, 137-147.
17. Thompson, R. L. & Sawtell, N. M. (2000) J. Virol. 74, 965-974.
18. Yang, Y. L., Reis, L. F., Pavlovic, J., Aguzzi, A., Schafer, R., Kumar, A., Williams, B. R., Aguet, M. & Weissmann, C. (1995) EMBO J. 14, 6095-6106.
19. Simpson, E. M., Linder, C. C., Sargent, E. E., Davisson, M. T., Mobraaten, L. E. & Sharp, J. J. (1997) Nat. Genet. 6, 19-27.
20. Zhou, A., Paranjape, J., Brown, T. L., Nie, H., Naik, S., Dong, B., Chang, A., Trapp, B., Fairchild, R., Colmenares, C., et al. (1997) EMBO J. 16, 6355-6363.
21. Clemens, M. & Williams, B. R. G. (1978) Cell 13, 565-572.
22. Zhou, A., Paranjape, J. M., Der, S. D., Williams, B. R. & Silverman, R. H. (1999) Virology 258, 435-440.
23. Whitley, R. J., Kern, E. R., Chatterjee, S., Chou, J. & Roizman, B. (1993) J. Clin. Invest. 91, 2837-2843.
24. Perng, G. C., Ghiasi, H., Slanina, S. M., Nesburn, A. B. & Wechsler, S. L. (1996) J. Virol. 70, 2883-2893.
25. Krmpotic, A., Messerle, M., Crnkovic-Mertens, I., Polic, B., Jonjic, S. & Koszinowski, U. H. (1999) J. Exp. Med. 190, 1285-1296.
26. Crnkovic-Mertens, I., Messerle, M., Milotic, I., Szepan, U., Kucic, N., Krmpotic, A., Jonjic, S. & Koszinowski, U. H. (1998) J. Virol. 72, 1377-1382.
27. Farrell, H. E., Vally, H., Lynch, D. M., Fleming, P., Shellam, G. R., Scalzo, A. A. & Davis-Poynter, N. J. (1997) Nature (London) 386, 510-514.
28. Goldsmith, K., Chen, W., Johnson, D. C. & Hendricks, R. L. (1998) J. Exp. Med. 187, 341-348.
29. Lubinski, J., Wang, L., Mastellos, D., Sahu, A., Lambris, J. D. & Friedman, H. M. (1999) J. Exp. Med. 190, 1637-1646.