Plasmid-based E6-specific siRNA and co-expression of wild-type p53 suppresses the growth of cervical cancer in vitro and in vivo

Cancer Letters

Volumn 335, Issue 1, 2013, Pages 242-250

  Li, Xin ^a   Li, Yang ^a   Hu, Jiadi ^b   Wang, Bo ^a   Zhao, Lijing ^a   Ji, Kun ^a   Guo, Baofeng ^a   Yin, Di ^a   Du, Yanwei ^a   Kopecko, Dennis J ^c   Kalvakolanu, Dhananjaya V ^d   Zhao, Xuejian ^a   Xu, Deqi ^e   Zhang, Ling ^a  

^a Basic Medical College   (China)

^b UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e New Vaccine National Engineering Research Center   (China)

Author keywords

Attenuated Salmonella typhimurium; Cervical cancer; E6; Gene therapy; P53

Indexed keywords

PROTEIN E6; PROTEIN P53; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GENE THERAPY; CANCER INHIBITION; CONTROLLED STUDY; E6 GENE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; P53 GENE; PLASMID; PRIORITY JOURNAL; UTERINE CERVIX CANCER;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; FEMALE; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GENETIC THERAPY; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRUS INFECTIONS; PLASMIDS; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; SALMONELLA TYPHIMURIUM; TRANSFORMATION, BACTERIAL; TUMOR BURDEN; TUMOR SUPPRESSOR PROTEIN P53; UTERINE CERVICAL NEOPLASMS;

HUMAN PAPILLOMAVIRUS TYPE 16; SALMONELLA TYPHIMURIUM;

EID: 84878468438     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.02.034     Document Type: Article

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