The synergistic therapeutic effect of cisplatin with Human papillomavirus E6/E7 short interfering RNA on cervical cancer cell lines in vitro and in vivo

International Journal of Cancer

Volumn 130, Issue 8, 2012, Pages 1925-1936

  Jung, Hun Soon ^a   Erkin, Ozgur Cem ^a   Kwon, Mi Jeong ^a   Kim, Seok Hyung ^b   Jung, Jae In ^c   Oh, Yu Kyoung ^a   Her, Song Wook ^c   Ju, Woong ^d   Choi, Yoon La ^b   Song, Sang Yong ^b   Kim, Joong Kyu ^e   Kim, Young Deug ^a   Shim, Ga Yong ^f   Shin, Young Kee ^a  

^a Seoul National University   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Korea Basic Science Institute (KBSI)   (South Korea)

^d Ewha Womans University School of Medicine   (South Korea)

^e EGen Biotech Co Ltd   (South Korea)

^f Korea University   (South Korea)

Author keywords

cervical carcinoma; chemosensitizer; cisplatin (CDDP) chemotherapy; HPV E6 E7 siRNA; human papillomavirus

Indexed keywords

CISPLATIN; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; FEMALE; HELA CELL; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 18; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; SENESCENCE; SPECIES DIFFERENCE; UTERINE CERVIX CANCER; VIRUS ONCOGENE; WART VIRUS;

ALPHAPAPILLOMAVIRUS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; CISPLATIN; COMBINED MODALITY THERAPY; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; MICE; MICE, NUDE; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRUS E7 PROTEINS; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; TUMOR BURDEN; UTERINE CERVICAL NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84857507756     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26197     Document Type: Article

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