Activation of p53 in cervical carcinoma cells by small molecules

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 15, 2000, Pages 8501-8506

  Hietanen, Sakari ^a,b   Lain, Sonia ^a   Krausz, Eberhard ^c   Blattner, Christine ^a   Lane, David P ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

^c CYCLACEL LTD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DACTINOMYCIN; LEPTOMYCIN B; MESSENGER RNA; PROTEIN P53; SMALL MOLECULE TRANSPORT AGENT;

ARTICLE; CANCER CELL CULTURE; DNA DAMAGE; ENZYME ACTIVITY; GENE ACTIVATION; GENE EXPRESSION; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; RISK FACTOR; RNA TRANSCRIPTION; TUMOR SUPPRESSOR GENE; UTERINE CERVIX CARCINOMA; WART VIRUS;

ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CELL NUCLEUS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DACTINOMYCIN; DNA-BINDING PROTEINS; DOWN-REGULATION; FATTY ACIDS, UNSATURATED; FEMALE; HELA CELLS; HUMANS; NEOPLASM PROTEINS; NUCLEAR PROTEINS; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRIDAE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UTERINE CERVICAL NEOPLASMS;

EID: 0034682468     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.15.8501     Document Type: Article

References (54)

1. zur Hausen, H. (1996) Biochim. Biophys. Acta 1288, F55-F78.
2. Park, D. J., Wilczynski, S. P., Paquette, R. L., Miller, C. W. & Koeffler, H. P. (1994) Oncogene 9, 205-210.
3. Scheffner, M. (1998) Pharmacol. Ther. 78, 129-139.
4. Scheffner, M., Werness, B. A., Huibregtse, J. M., Levine, A. J. & Howley, P. M. (1990) Cell 63, 1129-1136.
5. Kubbutat, M. H. & Vousden, K. H. (1998) Trends. Microbiol. 6, 173-175.
6. Rapp, L. & Chen, J. J. (1998) Biochim. Biophys. Acta 1378, F1-F19.
7. Bates, S. & Vousden, K. H. (1999) Cell Mol. Life Sci. 55, 28-37.
8. Haupt, Y., Maya, R., Kazaz, A. & Oren, M. (1997) Nature (London) 387, 296-299.
9. Kubbutat, M. H., Jones, S. N. & Vousden, K. H. (1997) Nature (London) 387, 299-303.
10. Midgley, C. A. & Lane, D. P. (1997) Oncogene 15, 1179-1189.
11. Kessis, T. D., Slebos, R. J., Nelson, W. G., Kastan, M. B., Plunkett, B. S., Han, S. M., Lorincz, A. T., Hedrick, L. & Cho, K. R. (1993) Proc. Natl. Acad. Sci. USA 90, 3988-3992.
12. Foster, S. A., Demers, G. W., Etscheid, B. G. & Galloway, D. A. (1994) J. Virol. 68, 5698-5705.
13. Liu, X., Han, S., Baluda, M. A. & Park, N. H. (1997) Oncogene 14, 2347-2353.
14. Butz, K., Shahabeddin, L., Geisen, C, Spitkovsky, D., Ullmann, A. & Hoppe-Seyler, F. (1995) Oncogene 10, 927-936.
15. Butz, K., Whitaker, N., Denk, C., Ullmann, A., Geisen, C. & Hoppe Seyler, F. (1999) Oncogene 18, 2381-2386.
16. von Knebel-Doeberitz, M., Rittmüller, C., Aengeneyndt, F., Jansen-Durr, P. & Spitkovsky, D. (1992) J. Virol. 51, 831-834.
17. Schaumberg, J. P., Hokanso, G. C. & French, J. C. (1984) J. Chem. Soc. Chem. Commun. 21. 1450-1452.
18. Fomerod, M., Ohno, M., Yoshida, M. & Mattaj, I. W. (1997) Cell 90, 1051-1060.
19. Roth, J., Dobbelstein, M., Freedman, D. A., Shenk, T. & Levine, A. J. (1998) EMBO J. 17, 554-564.
20. Freedman, D. A. & Levine, A. J. (1998) Mol. Cell. Biol. 18, 7288-7293.
21. Lain, S., Midgley, C., Sparks, A., Lane, E. B. & Lane, D. P. (1999) Exp. Cell Res. 248, 457-472.
22. Smart, P., Lane, E. B., Lane, D. P., Midgley, C, Vojtesek, B. & Lain, S. (1999) Oncogene 18, 7378-7386.
23. Ljungman, M., Zhang, F., Chen, F., Rainbow, A. J. & McKay, B. C. (1999) Oncogene 18, 583-592.
24. Blattner, C., Sparks, A. & Lane, D. (1999) Mol. Cell. Biol. 19, 3704-3713.
25. Brown, J. M. & Wouters, B. G. (1999) Cancer Res. 59, 1391-1399.
26. Bunz, F., Hwang, P. M., Torrance, C., Waldman, T., Zhang, Y., Dillehay, L., Williams, J., Lengauer, C., Kinzler, K. W. & Vogelstein, B. (1999) J. Clin. Invest. 104, 263-269.
27. Shaulian, E., Haviv, I., Shaul, Y. & Oren, M. (1995) Oncogene 10, 671-680.
28. Böttger, A., Böttger, V., Sparks, A., Liu, W. L., Howard, S. F. & Lane, D. P. (1997) Curr. Biol. 7, 860-869.
29. Kern, S. E., Pietenpol, J. A., Thiagalingam, S., Seymour, A., Kinzler, K. W. & Vogelstein, B. (1992) Science 256, 827-830.
30. Renzing, J. & Lane, D. P. (1995) Oncogene 10, 1865-1868.
31. Fredersdorf, S., Milne, A. W., Hall, P. A. & Lu, X. (1996) Am. J. Pathol. 148, 825-835.
32. Chen, J., Marechal, V. & Levine, A. J. (1993) Mol. Cell. Biol. 13, 4107-4114.
33. Rahmsdorf, H. J., Schonthal, A., Angel, P., Litfin, M., Ruther, U. & Herrlich, P. (1987) Nucleic Acids Res. 15, 1643-1659.
34. Smotkin, D. & Wettstein, F. O. (1986) Proc. Natl. Acad. Sci. USA 83, 4680-4684.
35. Pim, D., Massimi, P. & Banks, L. (1997) Oncogene 15, 257-264.
36. Prabhu, N. S., Somasundaram, K., Satyamoorthy, K., Herlyn, M. & el-Deiry, W. S. (1998) Int. J. Oncol. 13, 5-9.
37. D'Amours, D., Desnoyers, S., D'Silva, I. & Poirier, G. G. (1999) Biochem. J. 342, 249-268.
38. Dowhanick, J. J., Mcbride, A. A. & Howley, P. M. (1995) J. Virol. 69, 7791-7799.
39. Hwang, E. S., Naeger, L. K. & DiMaio, D. (1996) Oncogene 12, 795-803.
40. Steele, C, Cowsert, L. M. & Shillitoe, E. J. (1993) Cancer Res. 53, 2330-2337.
41. Lohrum, M. & Scheidtmann, K. H. (1996) Oncogene 13, 2527-2539.
42. An, W. G., Chuman, Y., Fojo, T. & Blagosklonny, M. V. (1998) Exp. Cell Res. 244, 54-60.
43. Weinberg, W. C., Azzoli, C. G., Chapman, K., Levine, A. J. & Yuspa, S. H. (1995) Oncogene 10, 2271-2279.
44. Jimenez, G. S., Khan, S. H., Stommel, J. M. & Wahl, G. M. (1999) Oncogene 18, 7656-7665.
45. Meek, D. W. (1999) Oncogene 18, 7666-7675.
46. Kudo, N., Taoka, H., Toda, T., Yoshida, M. & Horinouchi, S. (1999) J Biol. Chem. 274, 15151-15158.
47. Rodriguez, M. S., Thompson, J., Hay, R. T. & Dargemont, C. (1999) J Biol. Chem. 274, 9108-9115.
48. Daniels, P. R., Sanders, C. M. & Maitland, N. J. (1998) J. Gen. Virol. 79, 489-499.
49. Mantovani, F. & Banks, L. (1999) Oncogene 18, 3309-3315.
50. Kaghad, M., Bonnet, H., Yang, A., Creancier, L., Biscan, J. C., Valent, A., Minty, A., Chalon, P., Lelias, J. M., Dumont, X., et al. (1997) Cell 90, 809-819.
51. Gong, J. G., Costanzo, A., Yang, H. Q., Melino, G., Kaelin, W. G., Jr., Levrero, M. & Wang, J. Y. (1999) Nature (London) 399, 806-809.
52. Agami, R., Blandino, G., Oren, M. & Shaul, Y. (1999) Nature (London) 399, 809-813.
53. Yuan, Z. M., Shioya, H., Ishiko, T., Sun, X., Gu, J., Huang, Y. Y., Lu, H., Kharbanda, S., Weichselbaum, R. & Kufe, D. (1999) Nature (London) 399, 814-817.
54. Davison, T. S., Vagner, C., Kaghad, M., Ayed, A., Caput, D. & Arrowsmith, C. H. (1999) J. Biol. Chem. 274, 18709-18714.