MicroRNA expression in response to controlled exposure to diesel exhaust: Attenuation by the antioxidant N-acetylcysteine in a randomized crossover study

Environmental Health Perspectives

Volumn 121, Issue 6, 2013, Pages 670-675

  Yamamoto, Masatsugu ^a,b   Singh, Amrit ^a,c   Sava, Francesco ^a,b   Pui, Mandy ^a,b   Tebbutt, Scott J ^a,c   Carlsten, Christopher ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b VANCOUVER GENERAL HOSPITAL   (Canada)

^c Prevention of Organ Failure Centre of Excellence   (Canada)

Author keywords

Air pollution; Asthma; Controlled diesel exhaust exposure; Hsa miR 144; MicroRNA; N acetylcysteine; Nanostring ncounter assay; NRF2; Oxidative stress; Peripheral blood

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACETYLCYSTEINE; ANTIOXIDANT; METHACHOLINE; MICRORNA; MICRORNA 144; MICRORNA 21; MICRORNA 215; MICRORNA 30E; PLACEBO; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ASTHMA; BLOOD SAMPLING; CD3+ T LYMPHOCYTE; COMPARATIVE STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; ELISA KIT; ENVIRONMENTAL EXPOSURE; EXHAUST GAS; GENE EXPRESSION; HUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; VALIDATION PROCESS;

ACETYLCYSTEINE; ADULT; ANTIGENS, CD3; ANTIOXIDANTS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; HUMANS; MICRORNAS; NF-E2-RELATED FACTOR 2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VEHICLE EMISSIONS;

EID: 84878443918     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1205963     Document Type: Article

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